Abstract: Background: Breast milk may impact early brain
development, with potentially important biological, medical and
social implications. There is an important discussion on which is the
adequate breastfeeding extension to the development consolidation
and how the children breastfeeding affects their psychomotor
development, in the first year of life, and in following periods as
well. Some special fats (LC PUFA) contained in breast milk play a
key role in the brain’s maturation and cognitive development or
social skills. These capacities created during breastfeeding time
would be unfolded throughout all lifespan. Aim of the study: In our research, we have studied the effect of
breastfeeding in preschooler's psychomotor assessment.
Method: This study was conducted in a sample of 158 preschool
children in Vlorë, Albania. We have measured the psychometric
parameters of preschoolers with ASQ-3 (Age&Stage Questionnaires-
3). The studied sample was divided in three groups according to their
breastfeeding duration (3, 6 and 12 months). Results: Children breastfed for only 3 months have definitely
lower psychometric scores compared to the ones with 6 or more
months of breastfeeding (respectively 217 to 239 ASQ-3 scores). Six
and twelvemonth breastfed children have progressively more odds to
have high levels of psychomotor development comparing to those
with only 3 months of breastfeeding. The most affected psychometric
domains by shortness of breastfeeding are Communication and
Global motor. Conclusion: This leads to conclusion that to ensure high
psychomotor parameters during childhood is necessary breastfeeding
for at least 6 months.
Abstract: In the vicinity of red sea about 15 fungi species were
isolated from oil contaminated sites. On the basis of aptitude to
degrade the crude oil and DCPIP assay, two fungal isolates were
selected amongst 15 oil degrading strains. Analysis of ITS-1, ITS-2
and amplicon pyrosequencing studies of fungal diversity revealed
that these strains belong to Penicillium and Aspergillus species. Two
strains that proved to be the most efficient in degrading crude oil was
Aspergillus niger (54%) and Penicillium commune (48%) Subsequent
to two weeks of cultivation in BHS medium the degradation rate
were recorded by using spectrophotometer and GC-MS. Hence, it is
cleared that these fungal strains has capability of degradation and can
be utilize for cleaning the Saudi Arabian environment.
Abstract: The floor beams of steel buildings, cold-formed steel
floor joists in particular, often require large web openings, which may
affect their shear capacities. A cost effective way to mitigate the
detrimental effects of such openings is to weld/fasten reinforcements.
A difficulty associated with an experimental investigation to establish
suitable reinforcement schemes for openings in shear zone is that
moment always coexists with the shear, and thus, it is impossible to
create pure shear state in experiments, resulting in moment
influenced results. However, Finite Element Method (FEM) based
analysis can be conveniently used to investigate the pure shear
behaviour of webs including webs with reinforced openings. This
paper presents the details associated with the finite element analysis
of thick/thin-plates (representing the web of hot-rolled steel beam,
and the web of a cold-formed steel member) having a large
reinforced opening. The study considered simply-supported
rectangular plates subjected to in-plane shear loadings until failure
(including post-buckling behaviour). The plate was modelled using
geometrically non-linear quadrilateral shell elements, and non-linear
stress-strain relationship based on experiments. Total Langrangian
with large displacement/small strain formulation was used for such
analyses. The model also considered the initial geometric
imperfections. This study considered three reinforcement schemes,
namely, flat, lip, and angle reinforcements. This paper discusses the
modelling considerations and presents the results associated with the
various reinforcement schemes under consideration.
Abstract: Lateral Geniculate Nucleus (LGN) is the relay center
in the visual pathway as it receives most of the input information
from retinal ganglion cells (RGC) and sends to visual cortex. Low
threshold calcium currents (IT) at the membrane are the unique
indicator to characterize this firing functionality of the LGN neurons
gained by the RGC input. According to the LGN functional
requirements such as functional mapping of RGC to LGN, the
morphologies of the LGN neurons were developed. During the
neurological disorders like glaucoma, the mapping between RGC and
LGN is disconnected and hence stimulating LGN electrically using
deep brain electrodes can restore the functionalities of LGN. A
computational model was developed for simulating the LGN neurons
with three predominant morphologies each representing different
functional mapping of RGC to LGN. The firings of action potentials
at LGN neuron due to IT were characterized by varying the
stimulation parameters, morphological parameters and orientation. A
wide range of stimulation parameters (stimulus amplitude, duration
and frequency) represents the various strengths of the electrical
stimulation with different morphological parameters (soma size,
dendrites size and structure). The orientation (0-1800) of LGN
neuron with respect to the stimulating electrode represents the angle
at which the extracellular deep brain stimulation towards LGN
neuron is performed. A reduced dendrite structure was used in the
model using Bush–Sejnowski algorithm to decrease the
computational time while conserving its input resistance and total
surface area. The major finding is that an input potential of 0.4 V is
required to produce the action potential in the LGN neuron which is
placed at 100 μm distance from the electrode. From this study, it can
be concluded that the neuroprostheses under design would need to
consider the capability of inducing at least 0.4V to produce action
potentials in LGN.
Abstract: This paper describes the development of a DNA-based
nanobiosensor to detect the dengue virus in mosquito using
electrically active magnetic (EAM) nanoparticles as concentrator and
electrochemical transducer. The biosensor detection encompasses
two sets of oligonucleotide probes that are specific to the dengue
virus: the detector probe labeled with the EAM nanoparticles and the
biotinylated capture probe. The DNA targets are double hybridized to
the detector and the capture probes and concentrated from
nonspecific DNA fragments by applying a magnetic field.
Subsequently, the DNA sandwiched targets (EAM-detector probe–
DNA target–capture probe-biotin) are captured on streptavidin
modified screen printed carbon electrodes through the biotinylated
capture probes. Detection is achieved electrochemically by measuring
the oxidation–reduction signal of the EAM nanoparticles. Results
indicate that the biosensor is able to detect the redox signal of the
EAM nanoparticles at dengue DNA concentrations as low as 10
ng/μl.
Abstract: Nature constantly changes as a result of human
necessities. This change mostly feels in natural water sources which
are reconstructed with an effect of dams and motorways. In other
respects, visual quality of the landscape gets a new and different
character during and after the construction of dams and motorways.
Changing and specialization new landscapes will be very important
to protection-usage balance to explore sustainable usage facilities.
The main cause of the selection of Artvin city is that it has very
important geographical location and one of the most attraction points
in the World with its biodiversity, conservation areas and natural
landscape characteristics. Many hydroelectric station and 7 dams are
situated, 3 of them have already been built on the Çoruh River in the
province of Artvin. As a result of dams, motorways route were reshaped
and the ways which have already changed because of
elevation is directly affected several of natural destruction. In
contrast, many different reservoirs in Coruh Basin provide new vista
point that has high visual quality. In this study, we would like to
evaluate with sustainable landscape design in 76 km river corridor,
which is mainly based on Deriner, Borçka and Muratlı Dams and
determination of their basin-lakes recreational potential and
opportunities. Lastly, we are going to give some suggestion about the
potential of the corridor.
Abstract: The objective of this work is to carryout critical
comparison of different actuation mechanisms like electrostatic,
thermal, piezoelectric, and magnetic with reference to a micro
cantilever. The relevant parameters like force generated,
displacement are compared in actuation methods. With these results,
helps in choosing the best actuation method for a particular
application. In this study, Comsol/Multiphysics software is used.
Modeling and simulation is done by considering the micro cantilever
of same dimensions as an actuator using all the above mentioned
actuation techniques. In addition to their small size, micro actuators
consume very little power and are capable of accurate results. In this
work, a comparison of actuation mechanisms is done to decide the
efficient system in micro domain.
Abstract: Numerical study of the static response of
homogeneous clay stratum considering a wide range of cohesion and
subject to foundation loads is presented. The linear elastic–perfectly
plastic constitutive relation with the von Mises yield criterion were
utilised to develop a numerically cost effective finite element model
for the soil while imposing a rigid body constrain to the foundation
footing. From the analyses carried out, estimate of the bearing
capacity factor, Nc as well as the ultimate load-carrying capacities of
these soils, effect of cohesion on foundation settlements, stress fields
and failure propagation were obtained. These are consistent with
other findings in the literature and hence can be a useful guide in
design of safe foundations in clay soils for buildings and other
structure.
Abstract: This paper is concerned with the ways in which
Assisted Reproductive Technologies (ARTs) affect women’s lives
and perceptions regarding their infertility, contraception and
reproductive health. The paper is based on a qualitative feminist
survey study to explore and analyze issues arising from the use of
ARTs by women in New Delhi, the capital of India. A rapid growth in
the number of fertility clinics has been noticed recently. A critical
analysis of interviews revealed that these technologies are used and
developed for making profits at the cost of women’s lives. In this
way, these technologies are influencing and changing the traditional
patterns of motherhood requiring a rethinking about new ways of
reproduction introduced through the use of ARTs.
Abstract: Various nanomaterials can be used as a drug delivery
vehicles in nanomedicine, called nanocarriers. They can either be
organic or inorganic, synthetic or natural-based. Although synthetic
nanocarriers are easier to produce, they can often be toxic for the
organism and thus not suitable for use in treatment. From naturalbased
nanocarriers, the most commonly used are protein cages or
viral capsids. In this work, virus bacteriophage λ was used for
delivery of different cytotoxic drugs (cisplatin, carboplatin,
oxaliplatin and doxorubicin). Large quantities of phage λ were
obtained from phage λ-producing strain of E. coli cultivated in
medium with 0.2% maltose. After killing of E. coli with chloroform
and its removal by centrifugation, the phage was concentrated by
ultracentrifugation at 130 000×g and 4°C for 3 h. The encapsulation
of the drugs was performed by infusion method and four different
concentrations of the drugs were encapsulated (200; 100; 50; 25
μg·mL-1). Free drug molecules were removed by filtration. The
encapsulation was verified using the absorbance for doxorubicin and
atomic absorption spectrometry for platinum cytostatics. The amount
of encapsulated drug linearly increased with the increasing
concentration of applied drug with the determination coefficient
R2=0.989 for doxorubicin; R2=0.967 for cisplatin; R2=0.989 for
carboplatin and R2=0.996 for oxaliplatin. The overall encapsulation
efficiency was calculated as 50% for doxorubicin; 8% for cisplatin;
6% for carboplatin and 10% for oxaliplatin.
Abstract: Chatter vibrations, occurring during cutting process,
cause vibration between the cutting tool and workpiece, which
deteriorates surface roughness and reduces tool life. The purpose of
this study is to investigate the influence of cutting parameters and
tool construction on surface roughness and vibration in turning of
aluminum alloy AA2024. A new design of cutting tool is proposed,
which is filled up with epoxy granite in order to improve damping
capacity of the tool. Experiments were performed at the lathe using
carbide cutting insert coated with TiC and two different cutting tools
made of AISI 5140 steel. Taguchi L9 orthogonal array was applied to
design of experiment and to optimize cutting conditions. By the help
of signal-to-noise ratio and analysis of variance the optimal cutting
condition and the effect of the cutting parameters on surface
roughness and vibration were determined. Effectiveness of Taguchi
method was verified by confirmation test. It was revealed that new
cutting tool with epoxy granite has reduced vibration and surface
roughness due to high damping properties of epoxy granite in
toolholder.
Abstract: A geoelectric survey was carried out in some parts of
Angwan Gwari, an outskirt of Lapai Local Government Area on
Niger State which belongs to the Nigerian Basement Complex, with
the aim of evaluating the soil corrosivity, aquifer transmissivity and
protective capacity of the area from which aquifer characterisation
was made. The G41 Resistivity Meter was employed to obtain fifteen
Schlumberger Vertical Electrical Sounding data along profiles in a
square grid network. The data were processed using interpex 1-D
sounding inversion software, which gives vertical electrical sounding
curves with layered model comprising of the apparent resistivities,
overburden thicknesses, and depth. This information was used to
evaluate longitudinal conductance and transmissivities of the layers.
The results show generally low resistivities across the survey area
and an average longitudinal conductance variation from
0.0237Siemens in VES 6 to 0.1261Siemens in VES 15 with almost
the entire area giving values less than 1.0 Siemens. The average
transmissivity values range from 96.45 Ω.m2 in VES 4 to 299070
Ω.m2 in VES 1. All but VES 4 and VES14 had an average
overburden greater than 400 Ω.m2, these results suggest that the
aquifers are highly permeable to fluid movement within, leading to
the possibility of enhanced migration and circulation of contaminants
in the groundwater system and that the area is generally corrosive.
Abstract: Recently, many users have begun to frequently share
their opinions on diverse issues using various social media. Therefore,
numerous governments have attempted to establish or improve
national policies according to the public opinions captured from
various social media. In this paper, we indicate several limitations of
the traditional approaches to analyze public opinion on science and
technology and provide an alternative methodology to overcome these
limitations. First, we distinguish between the science and technology
analysis phase and the social issue analysis phase to reflect the fact that
public opinion can be formed only when a certain science and
technology is applied to a specific social issue. Next, we successively
apply a start list and a stop list to acquire clarified and interesting
results. Finally, to identify the most appropriate documents that fit
with a given subject, we develop a new logical filter concept that
consists of not only mere keywords but also a logical relationship
among the keywords. This study then analyzes the possibilities for the
practical use of the proposed methodology thorough its application to
discover core issues and public opinions from 1,700,886 documents
comprising SNS, blogs, news, and discussions.
Abstract: At a global level, water stewardship, water stress and
water security are crucial factors in tourism planning and
development considerations. Challenges associated with water is of
particular concern to the Maldives as there is limited availability of
freshwater, high dependency on desalinated water, and high unit cost
associated with desalinating water. While the Maldives is promoted
as an example of sustainable tourism, a key sustainability challenge
facing tourism dependent communities is the efficient use and
management of available water resources. A water crisis event in the
capital island of Maldives highlighted how precarious water related
issues are in this tourism dependent destination. Applying
netnography, the focus of this working paper is to present community
perceptions of how government policies addressed Malé Water and
Sewerage Company (MWSC) water crisis event.
Abstract: This paper presents a case study of using STATCOM to enhance the performance of Al-Qatraneh 33-kV transmission line. The location of the STATCOM was identified by maintaining minimum voltage drops at the 110 load nodes. The transmission line and the 110 load nodes have been modeled by MATLAB/Simulink. The suggested STATCOM and its location will increase the transmission capability of this transmission line and overcome the overload expected in the year 2020. The annual percentage loading rise has been considered as 14.35%. A graphical representation of the line-to-line voltages and the voltage drops at different load nodes is illustrated.
Abstract: Non-linear dynamic time history analysis is
considered as the most advanced and comprehensive analytical
method for evaluating the seismic response and performance of
multi-degree-of-freedom building structures under the influence of
earthquake ground motions. However, effective and accurate
application of the method requires the implementation of advanced
hysteretic constitutive models of the various structural components
including masonry infill panels. Sophisticated computational research
tools that incorporate realistic hysteresis models for non-linear
dynamic time-history analysis are not popular among the professional
engineers as they are not only difficult to access but also complex and
time-consuming to use. In addition, commercial computer programs
for structural analysis and design that are acceptable to practicing
engineers do not generally integrate advanced hysteretic models
which can accurately simulate the hysteresis behavior of structural
elements with a realistic representation of strength degradation,
stiffness deterioration, energy dissipation and ‘pinching’ under cyclic
load reversals in the inelastic range of behavior. In this scenario,
push-over or non-linear static analysis methods have gained
significant popularity, as they can be employed to assess the seismic
performance of building structures while avoiding the complexities
and difficulties associated with non-linear dynamic time-history
analysis. “Push-over” or non-linear static analysis offers a practical
and efficient alternative to non-linear dynamic time-history analysis
for rationally evaluating the seismic demands. The present paper is
based on the analytical investigation of the effect of distribution of
masonry infill panels over the elevation of planar masonry infilled
reinforced concrete [R/C] frames on the seismic demands using the
capacity spectrum procedures implementing nonlinear static analysis
[pushover analysis] in conjunction with the response spectrum
concept. An important objective of the present study is to numerically
evaluate the adequacy of the capacity spectrum method using
pushover analysis for performance based design of masonry infilled
R/C frames for near-field earthquake ground motions.
Abstract: Paper deals with the modeling and simulation of energy consumption and GHG production of two different modes of regional passenger transport – road and railway. These two transport modes use the same type of fuel – diesel. Modeling and simulation of the energy consumption in transport is often used due to calculation satisfactory accuracy and cost efficiency. Paper deals with the calculation based on EN standards and information collected from technical information from vehicle producers and characteristics of tracks. Calculation included maximal theoretical capacity of bus and train and real passenger’s measurement from operation. Final energy consumption and GHG production is calculated by using software simulation. In evaluation of the simulation is used system “well to wheel”.
Abstract: Targeted drug delivery is a method of delivering
medication to a patient in a manner that increases the concentration
of the medication in some parts of the body relative to others.
Targeted drug delivery seeks to concentrate the medication in the
tissues of interest while reducing the relative concentration of the
medication in the remaining tissues. This improves efficacy of the
while reducing side effects. In the present work, we investigate the
effect of magnetic field, flow rate and particle concentration on the
capturing of magnetic particles transported in a stent implanted
fluidic channel. Iron oxide magnetic nanoparticles (Fe3O4)
nanoparticles were synthesized via co-precipitation method. The
synthesized Fe3O4 nanoparticles were added in the de-ionized (DI)
water to prepare the Fe3O4 magnetic particle suspended fluid. This
fluid is transported in a cylindrical tube of diameter 8 mm with help
of a peristaltic pump at different flow rate (25-40 ml/min). A
ferromagnetic coil of SS 430 has been implanted inside the
cylindrical tube to enhance the capturing of magnetic nanoparticles
under magnetic field. The capturing of magnetic nanoparticles was
observed at different magnetic magnetic field, flow rate and particle
concentration. It is observed that capture efficiency increases from
47-67% at magnetic field 2-5kG, respectively at particle
concentration 0.6mg/ml and at flow rate 30 ml/min. However, the
capture efficiency decreases from 65 to 44% by increasing the flow
rate from 25 to 40 ml/min, respectively. Furthermore, it is observed
that capture efficiency increases from 51 to 67% by increasing the
particle concentration from 0.3 to 0.6 mg/ml, respectively.
Abstract: This paper focuses on the orbit avoidance strategy of
the optical remote sensing satellite. The optical remote sensing
satellite, moving along the Sun-synchronous orbit, is equipped with
laser warning equipment to alert CCD camera from laser attacks. This
paper explores the strategy of satellite avoidance to protect the CCD
camera and also the satellite. The satellite could evasive to several
target points in the orbital coordinates of virtual satellite. The so-called
virtual satellite is a passive vehicle which superposes the satellite at the
initial stage of avoidance. The target points share the consistent cycle
time and the same semi-major axis with the virtual satellite, which
ensures the properties of the satellite’s Sun-synchronous orbit remain
unchanged. Moreover, to further strengthen the avoidance capability
of satellite, it can perform multi-target-points avoid maneuvers. On
occasions of fulfilling the satellite orbit tasks, the orbit can be restored
back to virtual satellite through orbit maneuvers. There into, the avoid
maneuvers adopts pulse guidance. In addition, the fuel consumption is
optimized. The avoidance strategy discussed in this article is
applicable to optical remote sensing satellite when it is encountered
with hostile attack of space-based laser anti-satellite.
Abstract: Introduction: The process to build a better safety
culture, methods of error analysis, and preventive measures, starts
with an understanding of the effects when human factors engineering
refer to remote microscopic diagnosis in surgery and specially in
organ transplantation for the remote evaluation of the grafts. It has
been estimated that even in well-organized transplant systems an
average of 8% to 14% of the grafts (G) that arrive at the recipient
hospitals may be considered as diseased, injured, damaged or
improper for transplantation. Digital microscopy adds information on
a microscopic level about the grafts in Organ Transplant (OT), and
may lead to a change in their management. Such a method will
reduce the possibility that a diseased G, will arrive at the recipient
hospital for implantation. Aim: Ergonomics of Digital Microscopy
(DM) based on virtual slides, on Telemedicine Systems (TS) for
Tele-Pathological (TPE) evaluation of the grafts (G) in organ
transplantation (OT). Material and Methods: By experimental
simulation, the ergonomics of DM for microscopic TPE of Renal
Graft (RG), Liver Graft (LG) and Pancreatic Graft (PG) tissues is
analyzed. In fact, this corresponded to the ergonomics of digital
microscopy for TPE in OT by applying Virtual Slide (VS) system for
graft tissue image capture, for remote diagnoses of possible
microscopic inflammatory and/or neoplastic lesions. Experimentation
included: a. Development of an OTE-TS similar Experimental
Telemedicine System (Exp.-TS), b. Simulation of the integration of
TS with the VS based microscopic TPE of RG, LG and PG applying
DM. Simulation of the DM based TPE was performed by 2
specialists on a total of 238 human Renal Graft (RG), 172 Liver Graft
(LG) and 108 Pancreatic Graft (PG) tissues digital microscopic
images for inflammatory and neoplastic lesions on four electronic
spaces of the four used TS. Results: Statistical analysis of specialist‘s
answers about the ability to diagnose accurately the diseased RG, LG
and PG tissues on the electronic space among four TS (A,B,C,D)
showed that DM on TS for TPE in OT is elaborated perfectly on the
ES of a Desktop, followed by the ES of the applied Exp.-TS. Tablet
and Mobile-Phone ES seem significantly risky for the application of
DM in OT (p