Abstract: In this article, we propose an Intelligent Medical
Diagnostic System (IMDS) accessible through common
web-based interface, to on-line perform initial screening for
osteoporosis. The fundamental approaches which construct the
proposed system are mainly based on the fuzzy-neural theory,
which can exhibit superiority over other conventional technologies
in many fields. In diagnosis process, users simply answer
a series of directed questions to the system, and then they
will immediately receive a list of results which represents the
risk degrees of osteoporosis. According to clinical testing results,
it is shown that the proposed system can provide the general
public or even health care providers with a convenient, reliable,
inexpensive approach to osteoporosis risk assessment.
Abstract: Concerning the inpatient care the present situation is
characterized by intense charges of medical technology into the
clinical daily routine and an ever stronger integration of special
techniques into the clinical workflow. Medical technology is by now
an integral part of health care according to consisting general
accepted standards. Purchase and operation thereby represent an
important economic position and both are subject of everyday
optimisation attempts. For this purpose by now exists a huge number
of tools which conduce more likely to a complexness of the problem
by a comprehensive implementation. In this paper the advantages of
an integrative information-workflow on the life-cycle-management in
the region of medical technology are shown.
Abstract: Heart failure is the most common reason of death
nowadays, but if the medical help is given directly, the patient-s life
may be saved in many cases. Numerous heart diseases can be
detected by means of analyzing electrocardiograms (ECG). Artificial
Neural Networks (ANN) are computer-based expert systems that
have proved to be useful in pattern recognition tasks. ANN can be
used in different phases of the decision-making process, from
classification to diagnostic procedures. This work concentrates on a
review followed by a novel method.
The purpose of the review is to assess the evidence of healthcare
benefits involving the application of artificial neural networks to the
clinical functions of diagnosis, prognosis and survival analysis, in
ECG signals. The developed method is based on a compound neural
network (CNN), to classify ECGs as normal or carrying an
AtrioVentricular heart Block (AVB). This method uses three
different feed forward multilayer neural networks. A single output
unit encodes the probability of AVB occurrences. A value between 0
and 0.1 is the desired output for a normal ECG; a value between 0.1
and 1 would infer an occurrence of an AVB. The results show that
this compound network has a good performance in detecting AVBs,
with a sensitivity of 90.7% and a specificity of 86.05%. The accuracy
value is 87.9%.
Abstract: The incidence of oral cancer in Taiwan increased year
by year. It replaced the nasopharyngeal as the top incurrence among
head and neck cancers since 1994. Early examination and earlier
identification for earlier treatment is the most effective medical
treatment for these cancers. Although the government fully subsidized
the expenses with tremendous promotion program for oral cancer
screening, the citizen-s participation remained low. Purpose of this
study is to understand the factors affecting the citizens- behavior
intensions of taking an oral cancer screening. Based on the Theory of
Planned Behavior, this study adopted four distinctive variables in
explaining the captioned behavior intentions.700 questionnaires were
dispatched with 500 valid responses or 71.4% returned by the citizens
with an age 30 or above from the eastern counties of Taiwan. Test
results has shown that attitude toward, subjective norms of, and
perceived behavioral control over the oral cancer screening varied
from some demographic factors to another. The study proofed that
attitude toward, subjective norms of, and perceived behavioral control
over the oral cancer screening had positive impacts on the
corresponding behavior intention. The test concluded that the theory
of planned behavior was appropriate as a theoretical framework in
explaining the influencing factors of intentions of taking oral cancer
screening. This study suggested the healthcare professional should
provide high accessibility of screening services other than just
delivering knowledge on oral cancer to promote the citizens-
intentions of taking the captioned screening. This research also
provided a practical implication to the healthcare professionals when
formulating and implementing promotion instruments for lifting the
screening rate of oral cancer.
Abstract: Sensors possess several properties of physical
measures. Whether devices that convert a sensed signal into an
electrical signal, chemical sensors and biosensors, thus all these
sensors can be considered as an interface between the physical and
electrical equipment. The problem is the analysis of the multitudes of
saved settings as input variables. However, they do not all have the
same level of influence on the outputs. In order to identify the most
sensitive parameters, those that can guide users in gathering
information on the ground and in the process of model calibration
and sensitivity analysis for the effect of each change made.
Mathematical models used for processing become very complex.
In this paper a fuzzy rule-based system is proposed as a solution
for this problem. The system collects the available signals
information from sensors. Moreover, the system allows the study of
the influence of the various factors that take part in the decision
system. Since its inception fuzzy set theory has been regarded as a
formalism suitable to deal with the imprecision intrinsic to many
problems. At the same time, fuzzy sets allow to use symbolic models.
In this study an example was applied for resolving variety of
physiological parameters that define human health state. The
application system was done for medical diagnosis help. The inputs
are the signals expressed the cardiovascular system parameters, blood
pressure, Respiratory system paramsystem was done, it will be able
to predict the state of patient according any input values.
Abstract: In recent years, several severe large-scale influenza
outbreaks happened in many countries, such as SARS in 2005 or
H1N1 in 2009. Those influenza Epidemics have greatly impacts not
only on people-s life and health, but medical systems in different
countries. Although severe diseases are more experienced, they are not
fully controlled. Governments have different policies to control the
spreads of diseases. However, those policies have both positive and
negative social or economical influence on people and society.
Therefore, it is necessary and essential to develop an appropriate
model for evaluations of policies. Consequently, a proper measure can
be implemented to confront the diseases. The main goal of this study is
to develop a SIR-based model for the further evaluations of the
candidate policies during the influenza outbreaks.
Abstract: Engineered nanoparticles’ usage rapidly increased in
various applications in the last decade due to their unusual properties.
However, there is an ever increasing concern to understand their
toxicological effect in human health. Particularly, metal and metal
oxide nanoparticles have been used in various sectors including
biomedical, food and agriculture. But their impact on human health is
yet to be fully understood. In this present investigation, we assessed
the toxic effect of engineered nanoparticles (ENPs) including Ag,
MgO and Co3O4 nanoparticles (NPs) on human mesenchymal stem
cells (hMSC) adopting cell viability and cellular morphological
changes as tools The results suggested that silver NPs are more toxic
than MgO and Co3O4NPs. The ENPs induced cytotoxicity and
nuclear morphological changes in hMSC depending on dose. The cell
viability decreases with increase in concentration of ENPs. The
cellular morphology studies revealed that ENPs damaged the cells.
These preliminary findings have implications for the use of these
nanoparticles in food industry with systematic regulations.
Abstract: Pattern recognition is the research area of Artificial Intelligence that studies the operation and design of systems that recognize patterns in the data. Important application areas are image analysis, character recognition, fingerprint classification, speech analysis, DNA sequence identification, man and machine diagnostics, person identification and industrial inspection. The interest in improving the classification systems of data analysis is independent from the context of applications. In fact, in many studies it is often the case to have to recognize and to distinguish groups of various objects, which requires the need for valid instruments capable to perform this task. The objective of this article is to show several methodologies of Artificial Intelligence for data classification applied to biomedical patterns. In particular, this work deals with the realization of a Computer-Aided Detection system (CADe) that is able to assist the radiologist in identifying types of mammary tumor lesions. As an additional biomedical application of the classification systems, we present a study conducted on blood samples which shows how these methods may help to distinguish between carriers of Thalassemia (or Mediterranean Anaemia) and healthy subjects.
Abstract: This paper describes the Multilingual Virtual Simulated Patient framework. It has been created to train the social skills and testing the knowledge of primary health care medical students. The framework generates conversational agents which perform in serveral languages as virtual simulated patients that help to improve the communication and diagnosis skills of the students complementing their training process.
Abstract: Aloe vera has been used worldwide both for
pharmaceutical, food, and cosmetic industries due to the plethora of
biological activities of some of its metabolites. The aim of this study
was to evaluate the antifungal and antioxidant activities of the leaf
extract. The antifungal activity was determined by the agar-well
diffusion method against plant and human fungal pathogens. The
methanol and ethanol portions of the extracts studied were more
bioactive than ethyl acetate portion. It was also observed that the
activity was more pronounced on plant pathogen than human
pathogen except Candida albicans. This is an indication that the
extract has the potential to treat plant fungal infections. The Aloe
extract showed the significant antioxidant activity by the DPPH
radical scavenging method. Therefore, the Aloe extract provided as
natural antioxidant has been used in health foods for medical and
preservative purposes.
Abstract: Recent advancements in sensor technologies and
Wireless Body Area Networks (WBANs) have led to the
development of cost-effective healthcare devices which can be used
to monitor and analyse a person-s physiological parameters from
remote locations. These advancements provides a unique opportunity
to overcome current healthcare challenges of low quality service
provisioning, lack of easy accessibility to service varieties, high costs
of services and increasing population of the elderly experienced
globally. This paper reports on a prototype implementation of an
architecture that seamlessly integrates Wireless Body Area Network
(WBAN) with Web services (WS) to proactively collect
physiological data of remote patients to recommend diagnostic
services. Technologies based upon WBAN and WS can provide
ubiquitous accessibility to a variety of services by allowing
distributed healthcare resources to be massively reused to provide
cost-effective services without individuals physically moving to the
locations of those resources. In addition, these technologies can
reduce costs of healthcare services by allowing individuals to access
services to support their healthcare. The prototype uses WBAN body
sensors implemented on arduino fio platforms to be worn by the
patient and an android smart phone as a personal server. The
physiological data are collected and uploaded through GPRS/internet
to the Medical Health Server (MHS) to be analysed. The prototype
monitors the activities, location and physiological parameters such as
SpO2 and Heart Rate of the elderly and patients in rehabilitation.
Medical practitioners would have real time access to the uploaded
information through a web application.
Abstract: The zero inflated models are usually used in modeling
count data with excess zeros where the existence of the excess zeros
could be structural zeros or zeros which occur by chance. These type
of data are commonly found in various disciplines such as finance,
insurance, biomedical, econometrical, ecology, and health sciences
which involve sex and health dental epidemiology. The most popular
zero inflated models used by many researchers are zero inflated
Poisson and zero inflated negative binomial models. In addition, zero
inflated generalized Poisson and zero inflated double Poisson models
are also discussed and found in some literature. Recently zero
inflated inverse trinomial model and zero inflated strict arcsine
models are advocated and proven to serve as alternative models in
modeling overdispersed count data caused by excessive zeros and
unobserved heterogeneity. The purpose of this paper is to review
some related literature and provide a variety of examples from
different disciplines in the application of zero inflated models.
Different model selection methods used in model comparison are
discussed.
Abstract: The Siemens Healthcare Sector is one of the world's
largest suppliers to the healthcare industry and a trendsetter in
medical imaging and therapy, laboratory diagnostics, medical
information technology, and hearing aids.
Siemens offers its customers products and solutions for the entire
range of patient care from a single source – from prevention and
early detection to diagnosis, and on to treatment and aftercare. By
optimizing clinical workflows for the most common diseases,
Siemens also makes healthcare faster, better, and more cost effective.
The optimization of clinical workflows requires a
multidisciplinary focus and a collaborative approach of e.g. medical
advisors, researchers and scientists as well as healthcare economists.
This new form of collaboration brings together experts with deep
technical experience, physicians with specialized medical knowledge
as well as people with comprehensive knowledge about health
economics.
As Charles Darwin is often quoted as saying, “It is neither the
strongest of the species that survive, nor the most intelligent, but the
one most responsive to change," We believe that those who can
successfully manage this change will emerge as winners, with
valuable competitive advantage.
Current medical information and knowledge are some of the core
assets in the healthcare industry. The main issue is to connect
knowledge holders and knowledge recipients from various
disciplines efficiently in order to spread and distribute knowledge.
Abstract: This paper proposes a novel architecture for At-
Home medical care which enables senior citizens, patients
with chronic ailments and patients requiring post- operative
care to be remotely monitored in the comfort of their homes.
This architecture is implemented using sensors and wireless
networking for transmitting patient data to the hospitals,
health- care centers for monitoring by medical professionals.
Patients are equipped with sensors to measure their
physiological parameters, like blood pressure, pulse rate etc.
and a Wearable Data Acquisition Unit is used to transmit the
patient sensor data. Medical professionals can be alerted to
any abnormal variations in these values for diagnosis and
suitable treatment. Security threats and challenges inherent to
wireless communication and sensor network have been
discussed and a security mechanism to ensure data
confidentiality and source authentication has been proposed.
Symmetric key algorithm AES has been used for encrypting
the data and a patent-free, two-pass block cipher mode CCFB
has been used for implementing semantic security.
Abstract: The hospital and the health-care center of a
community, as a place for people-s life-care and health-care settings,
must provide more and better services for patients or residents. After
Establishing Electronic Medical Record (EMR) system -which is a
necessity- in the hospital, providing pervasive services is a further
step. Our objective in this paper is to use pervasive computing in a
case study of healthcare, based on EMR database that coordinates
application services over network to form a service environment for
medical and health-care. Our method also categorizes the hospital
spaces into 3 spaces: Public spaces, Private spaces and Isolated
spaces. Although, there are many projects about using pervasive
computing in healthcare, but all of them concentrate on the disease
recognition, designing smart cloths, or provide services only for
patient. The proposed method is implemented in a hospital. The
obtained results show that it is suitable for our purpose.
Abstract: Data Mining aims at discovering knowledge out of
data and presenting it in a form that is easily comprehensible to
humans. One of the useful applications in Egypt is the Cancer
management, especially the management of Acute Lymphoblastic
Leukemia or ALL, which is the most common type of cancer in
children.
This paper discusses the process of designing a prototype that can
help in the management of childhood ALL, which has a great
significance in the health care field. Besides, it has a social impact
on decreasing the rate of infection in children in Egypt. It also
provides valubale information about the distribution and
segmentation of ALL in Egypt, which may be linked to the possible
risk factors.
Undirected Knowledge Discovery is used since, in the case of this
research project, there is no target field as the data provided is
mainly subjective. This is done in order to quantify the subjective
variables. Therefore, the computer will be asked to identify
significant patterns in the provided medical data about ALL. This
may be achieved through collecting the data necessary for the
system, determimng the data mining technique to be used for the
system, and choosing the most suitable implementation tool for the
domain.
The research makes use of a data mining tool, Clementine, so as to
apply Decision Trees technique. We feed it with data extracted from
real-life cases taken from specialized Cancer Institutes. Relevant
medical cases details such as patient medical history and diagnosis
are analyzed, classified, and clustered in order to improve the disease
management.
Abstract: Privacy issues commonly discussed among
researchers, practitioners, and end-users in pervasive healthcare.
Pervasive healthcare systems are applications that can support
patient-s need anytime and anywhere. However, pervasive healthcare
raises privacy concerns since it can lead to situations where patients
may not be aware that their private information is being shared and
becomes vulnerable to threat. We have systematically analyzed the
privacy issues and present a summary in tabular form to show the
relationship among the issues. The six issues identified are medical
information misuse, prescription leakage, medical information
eavesdropping, social implications for the patient, patient difficulties
in managing privacy settings, and lack of support in designing
privacy-sensitive applications. We narrow down the issues and chose
to focus on the issue of 'lack of support in designing privacysensitive
applications' by proposing a privacy-sensitive architecture
specifically designed for pervasive healthcare monitoring systems.
Abstract: Environment today is featured with aging population,
increasing prevalence of chronic disease and complex of medical
treatment. Safe use of pharmaceutics relied very much on the efforts
made by both the health- related organizations and as well as the
government agencies. As far as the specialization concern in providing
health services to the patients, the government actively issued and
implemented the divisions of medical treatment and pharmaceutical to
improve the quality of care and to reduce medication errors and ensure
public health. Pharmaceutical sub-sector policy has been implemented
for 13 years. This study attempts to explore the factors that affect the
patients- behavior intention of refilling a prescription from a NHIB
pharmacy. Samples were those patients refilling their prescriptions
with the case NHIB pharmacies. A self-administered questionnaire
was used to collect respondents- information while the patients or
family members visit the pharmacy for the refilling. 1,200
questionnaires were dispatched in 37 pharmacies that randomly
selected from Pingtung City, Dongkang, Chaozhou, Hengchun areas.
732 responses were gained with 604 valid samples for further analyses.
Results of data analyses indicated that respondents- attitude,
subjective norm, perceived behavior control and behavior intentions
toward refilling behavior varied from some demographic variables to
another. This research also suggested adding actual behavior, either by
a self-report or observed, into the research.
Abstract: Visible Light Communication (VLC) offers advantages of low energy consumption, licence free and RF interference free operation. One application area for VLC is in the provision of health centred services circumventing issues of interference with any biomedical device within the environment. VLC performamce is affected by natural light restricting systems avilability and relibility. The paper presents an analysis of the performance of VLC systems under different meteorological conditions. The evaluation considered the impact of natural light as a function of different reflection surfaces in different room sizes.
Abstract: Thailand-s health system is challenged by the rising
number of patients and decreasing ratio of medical
practitioners/patients, especially in rural areas. This may tempt
inexperienced GPs to rush through the process of anamnesis with the
risk of incorrect diagnosis. Patients have to travel far to the hospital
and wait for a long time presenting their case. Many patients try to
cure themselves with traditional Thai medicine. Many countries are
making use of the Internet for medical information gathering,
distribution and storage. Telemedicine applications are a relatively
new field of study in Thailand; the infrastructure of ICT had
hampered widespread use of the Internet for using medical
information. With recent improvements made health and technology
professionals can work out novel applications and systems to help
advance telemedicine for the benefit of the people. Here we explore
the use of telemedicine for people with health problems in rural areas
in Thailand and present a Telemedicine Diagnosis System for Rural
Thailand (TEDIST) for diagnosing certain conditions that people
with Internet access can use to establish contact with Community
Health Centers, e.g. by mobile phone. The system uses a Web-based
input method for individual patients- symptoms, which are taken by
an expert system for the analysis of conditions and appropriate
diseases. The analysis harnesses a knowledge base and a backward
chaining component to find out, which health professionals should be
presented with the case. Doctors have the opportunity to exchange
emails or chat with the patients they are responsible for or other
specialists. Patients- data are then stored in a Personal Health Record.