Abstract: Co-crystal is believed to improve the solubility and
dissolution rates and thus, enhanced the bioavailability of poor water
soluble drugs particularly during the oral route of administration.
With the existing of poorly soluble drugs in pharmaceutical industry,
the screening of co-crystal formation using carbamazepine (CBZ) as
a model drug compound with dicarboxylic acids co-crystal formers
(CCF) namely fumaric (FA) and succinic (SA) acids in ethanol has
been studied. The co-crystal formations were studied by varying the
mol ratio values of CCF to CBZ to access the effect of CCF
concentration on the formation of the co-crystal. Solvent evaporation,
slurry and cooling crystallization which representing the solution
based method co-crystal screening were used. Based on the
differential scanning calorimetry (DSC) analysis, the melting point of
CBZ-SA in different ratio was in the range between 188oC-189oC.
For CBZ-FA form A and CBZ-FA form B the melting point in
different ratio were in the range of 174oC-175oC and 185oC-186oC
respectively. The product crystal from the screening was also
characterized using X-ray powder diffraction (XRPD). The XRPD
pattern profile analysis has shown that the CBZ co-crystals with FA
and SA were successfully formed for all ratios studied. The findings
revealed that CBZ-FA co-crystal were formed in two different
polymorphs. It was found that CBZ-FA form A and form B were
formed from evaporation and slurry crystallization methods
respectively. On the other hand, in cooling crystallization method,
CBZ-FA form A was formed at lower mol ratio of CCF to CBZ and
vice versa. This study disclosed that different methods and mol ratios
during the co-crystal screening can affect the outcome of co-crystal
produced such as polymorphic forms of co-crystal and thereof. Thus,
it was suggested that careful attentions is needed during the screening
since the co-crystal formation is currently one of the promising
approach to be considered in research and development for
pharmaceutical industry to improve the poorly soluble drugs.
Abstract: Today, the pollution due to non-degradable material
such as plastics, has led to studies about the development of
environmental-friendly material. Because of biodegradability
obtained from natural sources, polylactid acid (PLA) and ijuk fiber
are interesting to modify into a composite. This material is also
expected to reduce the impact of environmental pollution. Surface
modification of ijuk fiber through alkalinization with 0.25 M NaOH
solution for 30 minutes was aimed to enhance its compatibility to
PLA, in order to improve properties of the composite such as the
mechanical properties. Alkalinization of the ijuk fibers annihilates
some surface components such as lignin, wax and hemicelloluse, so
the pore on the surface clearly appeared, decreasing of the density
and diameter of the ijuk fibers. The change of the ijuk fiber properties
leads to increase the mechanical properties of PLA composites
reinforced the ijuk fibers through strengthening of the mechanical
interlocking with the PLA matrix. An addition to enhance the
distribution of the fibers in the PLA matrix, the stirring during DCM
solvent evaporation from the mixture of the ijuk fibers and the
dissolved-PLA can reduce amount of the trapped-voids and fibers
pull-out phenomena, which can decrease the mechanical properties of
the composite.
Abstract: Future flood can be predicted using the probable
maximum flood (PMF). PMF is calculated using the historical
discharge or rainfall data considering the other climatic parameters
remaining stationary. However climate is changing globally and the
key climatic variables are temperature, evaporation, rainfall and sea
level rise are likely to change. To develop scenarios to a basin or
catchment scale these important climatic variables should be
considered. Nowadays scenario based on climatic variables is more
suitable than PMF. Six scenarios were developed for a large Fitzroy
basin and presented in this paper.
Abstract: Wet scrubbers have found widespread use in cleaning
contaminated gas streams because of their ability to remove
particulates and based on the applications of scrubbing of marine
engine exhaust gases by spraying sea-water. In order to examine the
flow characteristics inside the scrubber, the model is designated with
flow properties of hot air and water sprayer. The flow dynamics of
evaporation of hot air by the injection of water droplets is the key
factor considered in this paper. The flow behavior inside the scrubber
was investigated from the previous works and to sum up the
evaporation rate with respect to the concentration of water droplets are
predicted to bring out the competent modelling. The numerical
analysis using CFD facilitates in understanding the problem better and
empathies the behavior of the model over its entire operating envelope.
Abstract: Liposome plays an important role in medical and
pharmaceutical science as e.g. nano scale drug carriers. Liposomes
are vesicles of varying size consisting of a spherical lipid bilayer and
an aqueous inner compartment. Magnet-driven liposome used for the
targeted delivery of drugs to organs and tissues. These liposome
preparations contain encapsulated drug components and finely
dispersed magnetic particles.
Liposomes are vesicles of varying size consisting of a spherical
lipid bilayer and an aqueous inner compartment that are generated in
vitro. These are useful in terms of biocompatibility, biodegradability,
and low toxicity, and can control biodistribution by changing the size,
lipid composition, and physical characteristics. Furthermore,
liposomes can entrap both hydrophobic and hydrophilic drugs and are
able to continuously release the entrapped substrate, thus being useful
drug carriers. Magnetic liposomes (MLs) are phospholipid vesicles
that encapsulate magneticor paramagnetic nanoparticles. They are
applied as contrast agents for magnetic resonance imaging (MRI).
The biological synthesis of nanoparticles using plant extracts plays
an important role in the field of nanotechnology. Green-synthesized
magnetite nanoparticles-protein hybrid has been produced by treating
Iron (III) / Iron (II) chloride with the leaf extract of Datura inoxia.
The phytochemicals present in the leaf extracts act as a reducing as
well stabilizing agents preventing agglomeration, which include
flavonoids, phenolic compounds, cardiac glycosides, proteins and
sugars.
The magnetite nanoparticles-protein hybrid has been trapped
inside the aqueous core of the liposome prepared by reversed phase
evaporation (REV) method using oleic and linoleic acid which has
been shown to be driven under magnetic field confirming the
formation magnetic liposome (ML). Chemical characterization of
stealth magnetic liposome has been performed by breaking the
liposome and release of magnetic nanoparticles. The presence iron
has been confirmed by colour complex formation with KSCN and
UV-Vis study using spectrophotometer Cary 60, Agilent.
This magnet driven liposome using nanoparticles-protein hybrid
can be a smart vesicles for the targeted drug delivery.
Abstract: This paper presents the application of the Discrete
Component Model for heating and evaporation to multi-component
biodiesel fuel droplets in direct injection internal combustion engines.
This model takes into account the effects of temperature gradient,
recirculation and species diffusion inside droplets. A distinctive
feature of the model used in the analysis is that it is based on the
analytical solutions to the temperature and species diffusion
equations inside the droplets. Nineteen types of biodiesel fuels are
considered. It is shown that a simplistic model, based on the
approximation of biodiesel fuel by a single component or ignoring
the diffusion of components of biodiesel fuel, leads to noticeable
errors in predicted droplet evaporation time and time evolution of
droplet surface temperature and radius.
Abstract: In oases, the surface water resources are becoming
increasingly scarce and groundwater resources, which generally have
a poor quality due to the high levels of salinity, are often
overexploited. Water saving have therefore become imperative for
better oases sustainability. If drip irrigation is currently recommended
in Morocco for saving water and valuing, its use in the sub-desert
areas does not keep water safe from high evaporation rates. An
alternative to this system would be the use of subsurface drip
irrigation. This technique is defined as an application of water under
the soil surface through drippers, which deliver water at rates
generally similar to surface drip irrigation. As subsurface drip
irrigation is a recently introduced in Morocco, a better understanding
of the infiltration process around a buried source, in local conditions,
and its impact on plant growth is necessarily required. This study
aims to contribute to improving the water use efficiency by testing
the performance of subsurface irrigation system, especially in areas
where water is a limited source. The objectives of this research are
performance evaluation in arid conditions of the subsurface drip
irrigation system for young date palms compared to the surface drip.
In this context, an experimental test is installed at a farmer’s field in
the area of Erfoud (Errachidia Province, southeastern Morocco),
using the subsurface drip irrigation system in comparison with the
classic drip system for young date palms. Flow measurement to
calculate the uniformity of the application of water was done through
two methods: a flow measurement of drippers above the surface and
another one underground. The latter method has also helped us to
estimate losses through evaporation for both irrigation techniques. In
order to compare the effect of two irrigation modes, plants were
identified for each type of irrigation to monitor certain agronomic
parameters (cumulative numbers of palms and roots development).
Experimentation referred to a distribution uniformity of about 88%;
considered acceptable for subsurface drip irrigation while it is around
80% for the surface drip irrigation. The results also show an increase
in root development and in the number of palm, as well as a
substantial water savings due to lower evaporation losses compared
to the classic drip irrigation.
The results of this study showed that subsurface drip irrigation is
an efficient technique, which allows sustainable irrigation in arid
areas.
Abstract: Oases are complex and fragile agro-ecosystems. They
have always existed in environments characterized by an arid climate,
scarcity of rainfall, high temperatures and high evaporation. These
palms have grown up despite the severity of the physical
characteristics thanks to the water's existence and irrigation practice.
The oases are generally spread along non-perennial rivers (wadis),
shallow water table or deep artesian groundwater. However, the
sustainability of oasis system is threatened by water scarcity and
declining of water table levels particularly in arid areas. Located in
the southern east area of Morocco, Tafilalet plain encompasses one of
the largest palm groves in the kingdom. In recent years, this area has
become increasingly threatened by water shortage and has seen a
sharp deterioration under the effect of several combined
anthropogenic and climatic factors. The Bayoud disease, successive
years of drought, Hassan Addakhil dam construction etc are all
factors that have affected both water and phoenicicole heritage of the
area. The objective of this study is to understand the interaction
between qualitative and quantitative degradation of groundwater
resources, and the palm grove dynamics, while reviewing the
assumption that groundwater resources contribute in a direct way to
the conservation of this oasis agroecosystem. A historical analysis
tracing both the oasis dynamics and the groundwater evolution has
been established. Data were collected from satellite images, surveys
with different actors (farmers, Regional Office for Agricultural
Development, Basin agency...). They were complemented by a
synthesis of numerous technical reports in the area. The results
showed that within 40 years, the thickness of the groundwater table
has dropped in 50 %. Along with this, there has been a downsizing of
date palm by 50 %. Areas with higher groundwater level were the
least affected by the downsizing. So we can say that the shallow
groundwater contribute significantly and directly to the water supply
of date palm through its root system, and largely ensures the oasis
ecosystem sustainability.
Abstract: Climate change will affect the hydrological cycle in
many different ways such as increase in evaporation and rainfalls.
There have been growing interests among researchers to identify the
nature of trends in historical rainfall data in many different parts of
the world. This paper examines the trends in annual maximum
rainfall data from 30 stations in New South Wales, Australia by using
two non-parametric tests, Mann-Kendall (MK) and Spearman’s Rho
(SR). Rainfall data were analyzed for fifteen different durations
ranging from 6 min to 3 days. It is found that the sub-hourly
durations (6, 12, 18, 24, 30 and 48 minutes) show statistically
significant positive (upward) trends whereas longer duration (subdaily
and daily) events generally show a statistically significant
negative (downward) trend. It is also found that the MK test and SR
test provide notably different results for some rainfall event durations
considered in this study. Since shorter duration sub-hourly rainfall
events show positive trends at many stations, the design rainfall data
based on stationary frequency analysis for these durations need to be
adjusted to account for the impact of climate change. These shorter
durations are more relevant to many urban development projects
based on smaller catchments having a much shorter response time.
Abstract: This paper is concerning the issues of behaviour of
lightweight expanded clay aggregates concrete exposed to high
temperature. Lightweight aggregates from expanded clay are
produced by firing of row material up to temperature 1050°C.
Lightweight aggregates have suitable properties in terms of volume
stability, when exposed to temperatures up to 1050°C, which could
indicate their suitability for construction applications with higher risk
of fire. The test samples were exposed to heat by using the standard
temperature-time curve ISO 834. Negative changes in resulting
mechanical properties, such as compressive strength, tensile strength,
and flexural strength were evaluated. Also visual evaluation of the
specimen was performed. On specimen exposed to excessive heat, an
explosive spalling could be observed, due to evaporation of
considerable amount of unbounded water from the inner structure of
the concrete.
Abstract: Because of high thermal efficiency and low CO2
emission, diesel engines are being used widely in many industrial
fields although it makes many PM and NOx which give both human
health and environment a negative effect. NOx regulations for diesel
engines, however, are being strengthened and it is impossible to meet
the emission standard without NOx reduction devices such as SCR
(Selective Catalytic Reduction), LNC (Lean NOx Catalyst), and LNT
(Lean NOx Trap). Among the NOx reduction devices, urea-SCR
system is known as the most stable and efficient method to solve the
problem of NOx emission. But this device has some issues associated
with the ammonia slip phenomenon which is occurred by shortage of
evaporation and thermolysis time, and that makes it difficult to achieve
uniform distribution of the injected urea in front of monolith.
Therefore, this study has focused on the mixing enhancement between
urea and exhaust gases to enhance the efficiency of the SCR catalyst
equipped in catalytic muffler by changing inlet gas temperature and
spray conditions to improve the spray uniformity of the urea water
solution. Finally, it can be found that various parameters such as inlet
gas temperature and injector and injection angles significantly affect
the evaporation and mixing of the urea water solution with exhaust
gases, and therefore, optimization of these parameters are required.
Abstract: The climate change is a main parameter which affects the element of hydrological cycle especially runoff. Then, the purpose of this study is to determine the impact of the climate change on surface runoff using land use map on 2008 and daily weather data during January 1, 1979 to September 30, 2010 for SWAT model. SWAT continuously simulate time model and operates on a daily time step at basin scale. The results present that the effect of temperature change cannot be clearly presented on the change of runoff while the rainfall, relative humidity and evaporation are the parameters for the considering of runoff change. If there are the increasing of rainfall and relative humidity, there is also the increasing of runoff. On the other hand, if there is the increasing of evaporation, there is the decreasing of runoff.
Abstract: Qatar’s primary source of fresh water is through
seawater desalination. Amongst the major processes that are
commercially available on the market, the most common large scale
techniques are Multi-Stage Flash distillation (MSF), Multi Effect
distillation (MED), and Reverse Osmosis (RO). Although commonly
used, these three processes are highly expensive down to high energy
input requirements and high operating costs allied with maintenance
and stress induced on the systems in harsh alkaline media. Beside that
cost, environmental footprint of these desalination techniques are
significant; from damaging marine eco-system, to huge land use, to
discharge of tons of GHG and huge carbon footprint.
Other less energy consuming techniques based on membrane
separation are being sought to reduce both the carbon footprint and
operating costs is membrane distillation (MD).
Emerged in 1960s, MD is an alternative technology for water
desalination attracting more attention since 1980s. MD process
involves the evaporation of a hot feed, typically below boiling point
of brine at standard conditions, by creating a water vapor pressure
difference across the porous, hydrophobic membrane. Main
advantages of MD compared to other commercially available
technologies (MSF and MED) and specially RO are reduction of
membrane and module stress due to absence of trans-membrane
pressure, less impact of contaminant fouling on distillate due to
transfer of only water vapor, utilization of low grade or waste heat
from oil and gas industries to heat up the feed up to required
temperature difference across the membrane, superior water quality,
and relatively lower capital and operating cost.
To achieve the objective of this study, state of the art flat-sheet
cross-flow DCMD bench scale unit was designed, commissioned, and
tested. The objective of this study is to analyze the characteristics and
morphology of the membrane suitable for DCMD through SEM
imaging and contact angle measurement and to study the water
quality of distillate produced by DCMD bench scale unit.
Comparison with available literature data is undertaken where
appropriate and laboratory data is used to compare a DCMD distillate
quality with that of other desalination techniques and standards.
Membrane SEM analysis showed that the PTFE membrane used
for the study has contact angle of 127º with highly porous surface
supported with less porous and bigger pore size PP membrane. Study
on the effect of feed solution (salinity) and temperature on water
quality of distillate produced from ICP and IC analysis showed that
with any salinity and different feed temperature (up to 70ºC) the
electric conductivity of distillate is less than 5 μS/cm with 99.99%
salt rejection and proved to be feasible and effective process capable
of consistently producing high quality distillate from very high feed
salinity solution (i.e. 100000 mg/L TDS) even with substantial
quality difference compared to other desalination methods such as
RO and MSF.
Abstract: A variety of routing techniques are available to develop surface runoff hydrographs from rainfall. The selection of runoff routing method is very vital as it is directly related to the type of watershed and the required degree of accuracy. There are different modelling softwares available to explore the rainfall-runoff process in urban areas. XPSTORM, a link-node based, integrated stormwater modelling software, has been used in this study for developing surface runoff hydrograph for a Golf course area located in Rockhampton in Central Queensland in Australia. Four commonly used methods, namely SWMM runoff, Kinematic wave, Laurenson, and Time-Area are employed to generate runoff hydrograph for design storm of this study area. In runoff mode of XPSTORM, the rainfall, infiltration, evaporation and depression storage for subcatchments were simulated and the runoff from the subcatchment to collection node was calculated. The simulation results are presented, discussed and compared. The total surface runoff generated by SWMM runoff, Kinematic wave and Time-Area methods are found to be reasonably close, which indicates any of these methods can be used for developing runoff hydrograph of the study area. Laurenson method produces a comparatively less amount of surface runoff, however, it creates highest peak of surface runoff among all which may be suitable for hilly region. Although the Laurenson hydrograph technique is widely acceptable surface runoff routing technique in Queensland (Australia), extensive investigation is recommended with detailed topographic and hydrologic data in order to assess its suitability for use in the case study area.
Abstract: In order to investigate the effect of drought stress and row spacing on grain yield and associated traits of Mungbean, an experiment was conducted as a factorial in based on randomized complete block design with three replications in Ilam station, Iran during 2008-2009 growing season. This experiment was conducted in four stages on one kind of Mungbean named Gohar. The experimental factors including (80, 110 and 140mm cumulative evaporation from class A pan) and row spacing (25, 50, and 75cm) were selected. The results of the experiment showed that the varieties affected by the treatment showed significant differences. The highest total yield was obtained in the condition in which evaporation of water was 80mm. Of course some traits such as grain yield did not show a significant difference between the conditions in which evaporation of the irrigation water was 80 and 110mm. The traits under study also showed a significant difference to different raw spacing. Row spacing of 50cm had a higher total yield compared to other raw spaces. It was due to the higher number of pods per plant and grain weight. The interaction of drought stress and row spacing showed that in the condition in which the row space is 50 cm and the evaporation of the irrigation water is 80mm, the highest number of grain is achieved.
Abstract: L-asparagine admixture Paranitrophenol (LAPNP) single crystals were grown successfully by solution method with slow evaporation technique at room temperature. Crystals of size 12mm×5 mm×3mm have been obtained in 15 days. The grown crystals were Brown color and transparent. The solubility of the grown samples has been found out at various temperatures. The lattice parameters of the grown crystals were determined by X-ray diffraction technique. The reflection planes of the sample were confirmed by the powder X-ray diffraction study and diffraction peaks were indexed. Fourier transform infrared (FTIR) studies were used to confirm the presence of various functional groups in the crystals. UV–visible absorption spectrum was recorded to study the optical transparency of grown crystal. The nonlinear optical (NLO) property of the grown crystal was confirmed by Kurtz–Perry powder technique and a study of its second harmonic generation efficiency in comparison with potassium dihydrogen phosphate (KDP) has been made. The mechanical strength of the crystal was estimated by Vickers hardness test. The grown crystals were subjected to thermo gravimetric and differential thermal analysis (TG/DTA). The dielectric behavior of the sample was also studied
Abstract: The aim of present work was to optimize the effect of Ethyl Cellulose (EC) and Polyvinyl Pyrrolidone (PVP) concentration in extended release solid dispersion of Glibenclamide using combination of hydrophilic and hydrophobic polymers such as Polyvinyl Pyrrolidone and Ethyl cellulose. The advantage of solid dispersion technique provides a unique approach to particle size reduction and increased rates of dissolution. The compatibility studies of the drug and polymers were studied by TLC and results suggested no interaction between drug and polymers. Solid dispersions of Glibenclamide were prepared by common solvent evaporation method using Polyvinyl Pyrrolidone and Ethyl cellulose. The results indicated that homogeneous or heterogeneous conditions during the preparation methods employed governed the internal structures of the polymer matrices while retaining the drug in an amorphous form. F2 formulation prepared by solid dispersion method, displayed extended drug release followed by Higuchi matrix model indicating diffusion release of GLB from polymer matrices.
Abstract: This paper describes the research carried out to develop a process to increase the NaCl percentage of crude salt which is obtained from the conventional solar evaporation process. In this study refined salt was produced from crude solar salt by a chemico-physical method which consists of coagulation, precipitation and filtration. Initially crude salt crystals were crushed and dissolved in water. Optimum amounts of calcium hydroxide, sodium carbonate and Polyaluminiumchloride (PAC) were added to the solution respectively.
Refined NaCl solution was separated out by a filtration process. The solution was tested for Total Suspended Solids, SO42-, Mg2+, Ca2+. With optimum dosage of reagents, the results showed that a level of 99.60% NaCl could be achieved. Further this paper discusses the economic viability of the proposed process. A 83% profit margin can be achieved by this process and it is an increase of 112.3% compared to the traditional process.
Abstract: These studies have been carried out on the behavior of pesticides in aquatic environments of marshes to monitoring water and sediment. A total of 25 water and 25 sediment samples were collected at five sampling station during April, June and September. 2013 the levels of organochlorine (OCP) pesticide as a case study to find out the extent of pesticide contamination and accumulation, in water was the concentration of OCPs (0.02, 0.066, 0.7, 0.8, 0.072, 0.058) ppb. In sediment was the concentration of OCPs (5.897, 10.987, 0.089, 0.096, 7.897, and 12.389) ppb respectively in DDT, DDE, Chlordane, Heptachlor, Lindane, and Endosulfan. There is a relationship between pesticides and sediment and water with physical properties because the concentrations of pesticide in water and sediment are not always in equilibrium Furthermore, when sediments are smaller, the rate of deposition is slower. There the wetlands of pesticides due to factors of high temperature and evaporation but used in the control of pesticides in water and sediment also there still exist a variety of organochlorine pesticide residues in water and sediments of wetlands.
Abstract: Physical vapor deposition under conditions of an obliquely incident flux results in a film formation with an inclined columnar structure. These columns will be oriented toward the vapor source because of the self-shadowing effect, and they are homogenously distributed on the substrate surface because of the limited surface diffusion ability of ad-atoms when there is no additional substrate heating.
In this work, the oblique angle electron beam evaporation technique is used to fabricate thin films containing inclined nanorods. The results demonstrate that depending on the thin film composition, the morphology of the nanorods is changed as well. The galvanostatic analysis of these thin film anodes reveals that a composite CuSn nanorods having approximately 900mAhg-1 of initial discharge capacity, performs higher electrochemical performance compared to pure Sn nanorods containing anode material. The long cycle life and the advanced electrochemical properties of the nanostructured composite electrode might be attributed to its improved mechanical tolerance and enhanced electrical conductivity depending on the Cu presence in the nanorods.