Abstract: In the recent past, discussing about sex among
children and youths was frowned at by traditional norms and as such
sexual discussions and behavior were approached with great respect.
Things are actually falling apart with the increasing number of young
people that engage in premarital sex. Due to lack of experience and
sex education, many young people are becoming increasingly
exposed to the risk of HIV infection. In the light of the above, this
study discussed premarital sex, HIV, and use of condom among
youths in Nigeria. Data for this study came from 2013 Nigeria
Demographic and Health Survey and other secondary data. The
survey revealed that only 18.5 percent of young women that had sex
in the 12 months preceding the survey used condom. Out of 3306
never-married sexually active men and women, 1728 representing 52
percent live in urban areas and 43 percent of them did not use
condom during sexual intercourse in the 12 months preceding the
survey. This study concludes that for there to be reduction in
prevalence of HIV/AIDS among Nigerian youths, there is need for
concerted effort to be made towards educating youths on the
expedient of the use of condom during sexual intercourse.
Abstract: Lateral Geniculate Nucleus (LGN) is the relay center
in the visual pathway as it receives most of the input information
from retinal ganglion cells (RGC) and sends to visual cortex. Low
threshold calcium currents (IT) at the membrane are the unique
indicator to characterize this firing functionality of the LGN neurons
gained by the RGC input. According to the LGN functional
requirements such as functional mapping of RGC to LGN, the
morphologies of the LGN neurons were developed. During the
neurological disorders like glaucoma, the mapping between RGC and
LGN is disconnected and hence stimulating LGN electrically using
deep brain electrodes can restore the functionalities of LGN. A
computational model was developed for simulating the LGN neurons
with three predominant morphologies each representing different
functional mapping of RGC to LGN. The firings of action potentials
at LGN neuron due to IT were characterized by varying the
stimulation parameters, morphological parameters and orientation. A
wide range of stimulation parameters (stimulus amplitude, duration
and frequency) represents the various strengths of the electrical
stimulation with different morphological parameters (soma size,
dendrites size and structure). The orientation (0-1800) of LGN
neuron with respect to the stimulating electrode represents the angle
at which the extracellular deep brain stimulation towards LGN
neuron is performed. A reduced dendrite structure was used in the
model using Bush–Sejnowski algorithm to decrease the
computational time while conserving its input resistance and total
surface area. The major finding is that an input potential of 0.4 V is
required to produce the action potential in the LGN neuron which is
placed at 100 μm distance from the electrode. From this study, it can
be concluded that the neuroprostheses under design would need to
consider the capability of inducing at least 0.4V to produce action
potentials in LGN.
Abstract: This paper describes the development of a DNA-based
nanobiosensor to detect the dengue virus in mosquito using
electrically active magnetic (EAM) nanoparticles as concentrator and
electrochemical transducer. The biosensor detection encompasses
two sets of oligonucleotide probes that are specific to the dengue
virus: the detector probe labeled with the EAM nanoparticles and the
biotinylated capture probe. The DNA targets are double hybridized to
the detector and the capture probes and concentrated from
nonspecific DNA fragments by applying a magnetic field.
Subsequently, the DNA sandwiched targets (EAM-detector probe–
DNA target–capture probe-biotin) are captured on streptavidin
modified screen printed carbon electrodes through the biotinylated
capture probes. Detection is achieved electrochemically by measuring
the oxidation–reduction signal of the EAM nanoparticles. Results
indicate that the biosensor is able to detect the redox signal of the
EAM nanoparticles at dengue DNA concentrations as low as 10
ng/μl.
Abstract: Diets high in processed foods have been found to lack
essential micro-nutrients for optimum human development and
overall health. Some micro-nutrients such as copper (Cu) have been
found to enhance the inflammatory response through its oxidative
functions, thereby having a role in cardiovascular disease, metabolic
syndrome, diabetes and related complications. This research study
was designed to determine if food crops could be bio-fortified with
micro-nutrients by growing sprouts on mineral fortified fiber mats. In
the feasibility study described in this contribution, recycled cellulose
fibers and clay, saturated with either micro-nutrient copper ions or
copper nanoparticles, were converted to a novel mineral-cellulose
fiber carrier of essential micro-nutrient and of antimicrobial
properties. Seeds of Medicago sativa (alfalfa), purchased from a
commercial, organic supplier were germinated on engineered
cellulose fiber mats. After the appearance of the first leaves, the
sprouts were dehydrated and analyzed for Cu content. Nutrient
analysis showed ~2 increase in Cu of the sprouts grown on the fiber
mats with copper particles, and ~4 increase on mats with ionic copper
as compared to the control samples. This study illustrates the
potential for the use of engineered mats as a viable way to increase
the micro-nutrient composition of locally-grown food crops and the
need for additional research to determine the uptake, nutritional
implications and risks of micro-nutrient bio-fortification.
Abstract: Nature constantly changes as a result of human
necessities. This change mostly feels in natural water sources which
are reconstructed with an effect of dams and motorways. In other
respects, visual quality of the landscape gets a new and different
character during and after the construction of dams and motorways.
Changing and specialization new landscapes will be very important
to protection-usage balance to explore sustainable usage facilities.
The main cause of the selection of Artvin city is that it has very
important geographical location and one of the most attraction points
in the World with its biodiversity, conservation areas and natural
landscape characteristics. Many hydroelectric station and 7 dams are
situated, 3 of them have already been built on the Çoruh River in the
province of Artvin. As a result of dams, motorways route were reshaped
and the ways which have already changed because of
elevation is directly affected several of natural destruction. In
contrast, many different reservoirs in Coruh Basin provide new vista
point that has high visual quality. In this study, we would like to
evaluate with sustainable landscape design in 76 km river corridor,
which is mainly based on Deriner, Borçka and Muratlı Dams and
determination of their basin-lakes recreational potential and
opportunities. Lastly, we are going to give some suggestion about the
potential of the corridor.
Abstract: Iranian architects had creative ways for constructing
the buildings in each climate. Some of these architectural elements
were made under the ground. Shovadan is one of these underground
spaces in hot-humid regions in Dezfoul and Shoushtar city that had
special functions and characteristics. In this paper some subjects such
as the history of Shovadan, its elements and effective factors in the
formation of Shovadan in Dezfool city are discussed.
Abstract: The current statuses of lifetime test of LaB6 hollow
cathode at the Lanzhou Institute of Physics (LIP), China, was
described. 5A LaB6 hollow cathode was design for LIPS-200 40mN
Xenon ion thruster, and it could be used for LHT-100 80 mN Hall
thruster, too. Life test of the discharge and neutralizer modes of LHC-5
hollow cathode were stared in October 2011, and cumulative operation
time reached 17,300 and 16,100 hours in April 2015, respectively. The
life of cathode was designed more than 11,000 hours. Parameters of
discharge and key structure dimensions were monitored in different
stage of life test indicated that cathodes were health enough. The test
will continue until the cathode cannot work or operation parameter is
not in normally. The result of the endurance test of cathode
demonstrated that the LaB6 hollow cathode is satisfied for the required
of thruster in life and performance.
Abstract: The objective of this work is to carryout critical
comparison of different actuation mechanisms like electrostatic,
thermal, piezoelectric, and magnetic with reference to a micro
cantilever. The relevant parameters like force generated,
displacement are compared in actuation methods. With these results,
helps in choosing the best actuation method for a particular
application. In this study, Comsol/Multiphysics software is used.
Modeling and simulation is done by considering the micro cantilever
of same dimensions as an actuator using all the above mentioned
actuation techniques. In addition to their small size, micro actuators
consume very little power and are capable of accurate results. In this
work, a comparison of actuation mechanisms is done to decide the
efficient system in micro domain.
Abstract: Routing in adhoc networks is a challenge as nodes are
mobile, and links are constantly created and broken. Present ondemand
adhoc routing algorithms initiate route discovery after a path
breaks, incurring significant cost to detect disconnection and
establish a new route. Specifically, when a path is about to be broken,
the source is warned of the likelihood of a disconnection. The source
then initiates path discovery early, avoiding disconnection totally. A
path is considered about to break when link availability decreases.
This study modifies Adhoc On-demand Multipath Distance Vector
routing (AOMDV) so that route handoff occurs through link
availability estimation.
Abstract: In this paper, the unstable angle of attack of a
FOXTROT aircraft is controlled by using Genetic Algorithm based
flight controller and the result is compared with the conventional
techniques like Tyreus-Luyben (TL), Ziegler-Nichols (ZN) and
Interpolation Rule (IR) for tuning the PID controller. In addition, the
performance indices like Mean Square Error (MSE), Integral Square
Error (ISE), and Integral Absolute Time Error (IATE) etc. are
improved by using Genetic Algorithm. It was established that the
error by using GA is very less as compared to the conventional
techniques thereby improving the performance indices of the
dynamic system.
Abstract: Given the increase in the number of e-commerce sites,
the number of competitors has become very important. This means
that companies have to take appropriate decisions in order to meet the
expectations of their customers and satisfy their needs. In this paper,
we present a case study of applying LRFM (length, recency,
frequency and monetary) model and clustering techniques in the
sector of electronic commerce with a view to evaluating customers’
values of the Moroccan e-commerce websites and then developing
effective marketing strategies. To achieve these objectives, we adopt
LRFM model by applying a two-stage clustering method. In the first
stage, the self-organizing maps method is used to determine the best
number of clusters and the initial centroid. In the second stage, kmeans
method is applied to segment 730 customers into nine clusters
according to their L, R, F and M values. The results show that the
cluster 6 is the most important cluster because the average values of
L, R, F and M are higher than the overall average value. In addition,
this study has considered another variable that describes the mode of
payment used by customers to improve and strengthen clusters’
analysis. The clusters’ analysis demonstrates that the payment method is
one of the key indicators of a new index which allows to assess the
level of customers’ confidence in the company's Website.
Abstract: Numerical study of the static response of
homogeneous clay stratum considering a wide range of cohesion and
subject to foundation loads is presented. The linear elastic–perfectly
plastic constitutive relation with the von Mises yield criterion were
utilised to develop a numerically cost effective finite element model
for the soil while imposing a rigid body constrain to the foundation
footing. From the analyses carried out, estimate of the bearing
capacity factor, Nc as well as the ultimate load-carrying capacities of
these soils, effect of cohesion on foundation settlements, stress fields
and failure propagation were obtained. These are consistent with
other findings in the literature and hence can be a useful guide in
design of safe foundations in clay soils for buildings and other
structure.
Abstract: Broiler slaughter waste has become a major source of
pollution throughout the world. Utilization of broiler slaughter waste
by dry rendering process produced Rendered Chicken Oil (RCO), a
cheap raw material for biodiesel production and Carcass Meal a feed
ingredient for pets and fishes. Conversion of RCO into biodiesel may
open new vistas for generating wealth from waste besides controlling
the major havoc of environmental pollution. A two-step process to
convert RCO to good quality Biodiesel was invented. Acid catalysed
esterification of FFA followed by base catalysed transesterification of
triglycerides was carried out after meticulously standardizing the
methanol molar ratio, catalyst concentration, reaction temperature,
and reaction time to obtain the maximum biodiesel yield of 97.62%
and lowest glycerol yield of 6.96%. RCO biodiesel blend was tested
in a CRDI diesel engine. The results revealed that the blending of
commercial diesel with 20% RCO biodiesel (B20) lead to less engine
wear, a quieter engine and better fuel economy. The better lubricating
qualities of RCO B20 prevented over heating of engine, which
prolongs the engine life. RCO B20 can reduce the import of crude oil
and substantially reduce the engine emissions as proved by
significantly lower smoke levels, thus mitigating climatic changes.
Abstract: The main cause of Alzheimer disease (AD) was
believed to be mainly due to the accumulation of free radicals owing
to oxidative stress (OS) in brain tissue. The mechanism of the
neurotoxicity of Aluminum chloride (AlCl3) induced AD in
hippocampus Albino wister rat brain tissue, the curative & the
protective effects of Lipidium sativum group (LS) water extract were
assessed after 8 weeks by attenuated total reflection spectroscopy
ATR-IR and histologically by light microscope. ATR-IR results
revealed that the membrane phospholipid undergo free radical
attacks, mediated by AlCl3, primary affects the polyunsaturated fatty
acids indicated by the increased of the olefinic -C=CH sub-band area
around 3012 cm-1 from the curve fitting analysis. The narrowing in
the half band width (HBW) of the sνCH2 sub-band around 2852 cm-1
due to Al intoxication indicates the presence of trans form fatty acids
rather than gauch rotomer. The degradation of hydrocarbon chain to
shorter chain length, increasing in membrane fluidity, disorder, and
decreasing in lipid polarity in AlCl3 group indicated by the detected
changes in certain calculated area ratios compared to the control.
Administration of LS was greatly improved these parameters
compared to the AlCl3 group. Al influences the Aβ aggregation and
plaque formation, which in turn interferes to and disrupts the
membrane structure. The results also showed a marked increase in
the β-parallel and antiparallel structure, that characterize the Aβ
formation in Al-induced AD hippocampal brain tissue, indicated by
the detected increase in both amide I sub-bands around 1674, 1692
cm-1. This drastic increase in Aβ formation was greatly reduced in the
curative and protective groups compared to the AlCl3 group and
approached nearly the control values. These results supported too by
the light microscope. AlCl3 group showed significant marked
degenerative changes in hippocampal neurons. Most cells appeared
small, shrieked and deformed. Interestingly, the administration of LS
in curative and protective groups markedly decreases the amount of
degenerated cells compared to the non-treated group. In addition, the
intensity of congo red stained cells was decreased. Hippocampal
neurons looked more/or less similar to those of control. This study showed a promising therapeutic effect of Lipidium
sativum group (LS) on AD rat model that seriously overcome the
signs of oxidative stress on membrane lipid and restore the protein
misfolding.
Abstract: Lagos urban mini bus drivers play a critical role in the
transportation sector. The current major mode of transportation
within Lagos metropolis remains road transportation and this
confirms the relevance of urban mini-bus drivers in transporting the
populace to their various destinations. Other modes of transportation
such as the train and waterways are currently inadequate. Various
threats to the well-being of urban bus drivers include congested
traffic typical of modern day lifestyles, dwindling financial returns
due to long hours in traffic, fewer hours of sleep, inadequate diet,
time pressure, and assaults related to fare disputes. Several healthrelated
problems have been documented to be associated with urban
bus driving. For instance, greater rates of hypertension, obesity and
cholesterol level have been reported. Research studies are yet to
identify the influence of age and marital status on the well-being of
urban mini-bus drivers in Lagos metropolis. A study of this nature is
necessary as it is culturally perceived in Nigeria that older and
married people are especially influenced by family affiliation and
would behave in ways that would project positive outcomes. The
study sample consisted of 150 urban mini-bus drivers who were
conveniently sampled from six (6) different terminuses where their
journey begins and terminates. The well-being questionnaire was
administered to participants. The criteria for inclusion in the study
included the ability to read in English language and the confirmation
that interested participants were on duty and suited to be driving
mini-buses. Due to the nature of the job of bus driving, the researcher
administered the questionnaires on participants who were free and
willing to respond to the survey. All participants were males of
various age groups and of different marital statuses. Results of
analyses conducted revealed no significant influence of age and
marital status on the well-being of urban mini-bus drivers. This
indicates that the well-being of urban mini bus drivers is not
influenced by age or marital status. The findings of this study have
cultural implications. It negates the popularly held belief that older
and married people care more about their well-being than younger
and single people. It brings to fore the need to also identify and
consider other factors when certifying people for the job of urban bus
driving.
Abstract: This study was aimed to measure effective transverse
relaxation rates (R2*) in the liver and muscle of normal New Zealand
White (NZW) rabbits. R2* relaxation rate has been widely used in
various hepatic diseases for iron overload by quantifying iron contents
in liver. R2* relaxation rate is defined as the reciprocal of T2*
relaxation time and mainly depends on the constituents of tissue.
Different tissues would have different R2* relaxation rates. The signal
intensity decay in Magnetic resonance imaging (MRI) may be
characterized by R2* relaxation rates. In this study, a 1.5T GE Signa
HDxt whole body MR scanner equipped with an 8-channel high
resolution knee coil was used to observe R2* values in NZW rabbit’s
liver and muscle. Eight healthy NZW rabbits weighted 2 ~ 2.5 kg were
recruited. After anesthesia using Zoletil 50 and Rompun 2% mixture,
the abdomen of rabbit was landmarked at the center of knee coil to
perform 3-plane localizer scan using fast spoiled gradient echo
(FSPGR) pulse sequence. Afterwards, multi-planar fast gradient echo
(MFGR) scans were performed with 8 various echo times (TEs) to
acquire images for R2* measurements. Regions of interest (ROIs) at
liver and muscle were measured using Advantage workstation.
Finally, the R2* was obtained by a linear regression of ln(sı) on TE.
The results showed that the longer the echo time, the smaller the signal
intensity. The R2* values of liver and muscle were 44.8 ± 10.9 s-1 and
37.4 ± 9.5 s-1, respectively. It implies that the iron concentration of
liver is higher than that of muscle. In conclusion, the more the iron
contents in tissue, the higher the R2*. The correlations between R2*
and iron content in NZW rabbits might be valuable for further
exploration.
Abstract: This paper is concerned with the ways in which
Assisted Reproductive Technologies (ARTs) affect women’s lives
and perceptions regarding their infertility, contraception and
reproductive health. The paper is based on a qualitative feminist
survey study to explore and analyze issues arising from the use of
ARTs by women in New Delhi, the capital of India. A rapid growth in
the number of fertility clinics has been noticed recently. A critical
analysis of interviews revealed that these technologies are used and
developed for making profits at the cost of women’s lives. In this
way, these technologies are influencing and changing the traditional
patterns of motherhood requiring a rethinking about new ways of
reproduction introduced through the use of ARTs.
Abstract: Various nanomaterials can be used as a drug delivery
vehicles in nanomedicine, called nanocarriers. They can either be
organic or inorganic, synthetic or natural-based. Although synthetic
nanocarriers are easier to produce, they can often be toxic for the
organism and thus not suitable for use in treatment. From naturalbased
nanocarriers, the most commonly used are protein cages or
viral capsids. In this work, virus bacteriophage λ was used for
delivery of different cytotoxic drugs (cisplatin, carboplatin,
oxaliplatin and doxorubicin). Large quantities of phage λ were
obtained from phage λ-producing strain of E. coli cultivated in
medium with 0.2% maltose. After killing of E. coli with chloroform
and its removal by centrifugation, the phage was concentrated by
ultracentrifugation at 130 000×g and 4°C for 3 h. The encapsulation
of the drugs was performed by infusion method and four different
concentrations of the drugs were encapsulated (200; 100; 50; 25
μg·mL-1). Free drug molecules were removed by filtration. The
encapsulation was verified using the absorbance for doxorubicin and
atomic absorption spectrometry for platinum cytostatics. The amount
of encapsulated drug linearly increased with the increasing
concentration of applied drug with the determination coefficient
R2=0.989 for doxorubicin; R2=0.967 for cisplatin; R2=0.989 for
carboplatin and R2=0.996 for oxaliplatin. The overall encapsulation
efficiency was calculated as 50% for doxorubicin; 8% for cisplatin;
6% for carboplatin and 10% for oxaliplatin.
Abstract: Recovering resources from water purification sludge
(WPS) have been gradually stipulated in environmental protection
laws and regulations in many nations. Hence, reusing the WPS is
becoming an important topic, and recovering alum from WPS is one of
the many practical alternatives. Most previous research efforts have
been conducted on studying the amphoteric characteristic of aluminum
hydroxide for investigating the optimum pH range to dissolve the
Al(III) species from WPS, but it has been lack of reaction kinetics or
mechanisms related discussion. Therefore, in this investigation, water
purification sludge (WPS) solution was broken by ultrasound to make
particle size of reactants smaller, specific surface area larger.
According to the reaction kinetics, these phenomena let the dissolved
aluminum salt quantity increased and the reaction rate go faster.
Abstract: The practical efficient approach is suggested for
estimation of the seismoacoustic sources energy in C-OTDR
monitoring systems. This approach is represents the sequential plan
for confidence estimation both the seismoacoustic sources energy, as
well the absorption coefficient of the soil. The sequential plan
delivers the non-asymptotic guaranteed accuracy of obtained
estimates in the form of non-asymptotic confidence regions with
prescribed sizes. These confidence regions are valid for a finite
sample size when the distributions of the observations are unknown.
Thus, suggested estimates are non-asymptotic and nonparametric,
and also these estimates guarantee the prescribed estimation accuracy
in form of prior prescribed size of confidence regions, and prescribed
confidence coefficient value.