Abstract: MicroRNAs are small non-coding RNA found in
many different species. They play crucial roles in cancer such as
biological processes of apoptosis and proliferation. The identification
of microRNA-target genes can be an essential first step towards to
reveal the role of microRNA in various cancer types. In this paper,
we predict miRNA-target genes for lung cancer by integrating
prediction scores from miRanda and PITA algorithms used as a
feature vector of miRNA-target interaction. Then, machine-learning
algorithms were implemented for making a final prediction. The
approach developed in this study should be of value for future studies
into understanding the role of miRNAs in molecular mechanisms
enabling lung cancer formation.
Abstract: By using an adequate thermal barrier coating in
buildings the energy saving will be happened. In this study, a range
of wall paints with different absorption coefficient in different
climates has been investigated. In order to study these effects, heating
and cooling loads of a common building with different ordinary
paints and paint with mineral coating have been calculated. The
effect of building paint in different climatic condition was studied
and comparison was done between ordinary paints and paint with
mineral insulators in temperate climate to obtain optimized energy
consumption. The results have been shown that coatings with
inorganic micro particles as insulation reduce the energy
consumption of buildings around 14%.
Abstract: In order to understand whether there is a better than the
learning function of learning methods and improve the CAD Courses
for enterprise’s design human resource development, this research is
applied in learning practical learning computer graphics software. In
this study, Revit building information model for learning content,
design of two different modes of learning curriculum to learning,
learning functions, respectively, and project learning. Via a post-test,
questionnaires and student interviews, etc., to study the effectiveness
of a comparative analysis of two different modes of learning. Students
participate in a period of three weeks after a total of nine-hour course,
and finally written and hands-on test. In addition, fill in the
questionnaire response by the student learning, a total of fifteen
questionnaire title, problem type into the base operating software,
application software and software-based concept features three
directions. In addition to the questionnaire, and participants were
invited to two different learning methods to conduct interviews to
learn more about learning students the idea of two different modes.
The study found that the ad hoc short-term courses in learning, better
learning outcomes. On the other hand, functional style for the whole
course students are more satisfied, and the ad hoc style student is
difficult to accept the ad hoc style of learning.
Abstract: In this paper, an attempt has been made to analyze the effect of wall window orientation on Daylight Illuminance Ratio (DIR) and energy saving in a building known as “SODHA BERS COMPLEX (SBC)” at Varanasi, UP, India. The building has been designed incorporating all passive concepts for thermal comfort as well daylighting concepts to maximize the use of natural daylighting for the occupants in the day to day activities. The annual average DIR and the energy saving has been estimated by using the DIR model for wall window with different orientations under clear sky condition. It has been found that for south oriented window the energy saving per square meter is more compared to the other orientations due to the higher level of solar insolation for the south window in northern hemisphere whereas energy saving potential is minimum for north oriented wall window. The energy saving potential was 26%, 81% and 51% higher for east, south and west oriented window in comparison to north oriented window. The average annual DIR has same trends of variation as the annual energy saving and it is maximum for south oriented window and minimum for north oriented window.
Abstract: The effectiveness of microchannels in enhancing heat
transfer has been demonstrated in the semiconductor industry. In
order to tap the microscale heat transfer effects into macro
geometries, overcoming the cost and technological constraints,
microscale passages were created in macro geometries machined
using conventional fabrication methods. A cylindrical insert was
placed within a pipe, and geometrical profiles were created on the
outer surface of the insert to enhance heat transfer under steady-state
single-phase liquid flow conditions. However, while heat transfer
coefficient values of above 10 kW/m2·K were achieved, the heat
transfer enhancement was accompanied by undesirable pressure drop
increment. Therefore, this study aims to address the high pressure
drop issue using Constructal theory, a universal design law for both
animate and inanimate systems. Two designs based on Constructal theory were developed to study
the effectiveness of Constructal features in reducing the pressure drop
increment as compared to parallel channels, which are commonly
found in microchannel fabrication. The hydrodynamic and heat
transfer performance for the Tree insert and Constructal fin (Cfin)
insert were studied using experimental methods, and the underlying
mechanisms were substantiated by numerical results. In technical
terms, the objective is to achieve at least comparable increment in
both heat transfer coefficient and pressure drop, if not higher
increment in the former parameter. Results show that the Tree insert improved the heat transfer
performance by more than 16 percent at low flow rates, as compared
to the Tree-parallel insert. However, the heat transfer enhancement
reduced to less than 5 percent at high Reynolds numbers. On the
other hand, the pressure drop increment stayed almost constant at 20
percent. This suggests that the Tree insert has better heat transfer
performance in the low Reynolds number region. More importantly,
the Cfin insert displayed improved heat transfer performance along
with favourable hydrodynamic performance, as compared to Cfinparallel
insert, at all flow rates in this study. At 2 L/min, the
enhancement of heat transfer was more than 30 percent, with 20
percent pressure drop increment, as compared to Cfin-parallel insert.
Furthermore, comparable increment in both heat transfer coefficient
and pressure drop was observed at 8 L/min. In other words, the Cfin
insert successfully achieved the objective of this study. Analysis of the results suggests that bifurcation of flows is
effective in reducing the increment in pressure drop relative to heat
transfer enhancement. Optimising the geometries of the Constructal
fins is therefore the potential future study in achieving a bigger stride
in energy efficiency at much lower costs.
Abstract: Digital technologies offer many opportunities in the
design and implementation of brand communication and advertising.
Augmented reality (AR) is an innovative technology in marketing
communication that focuses on the fact that virtual interaction with a
product ad offers additional value to consumers. AR enables
consumers to obtain (almost) real product experiences by the way of
virtual information even before the purchase of a certain product.
Aim of AR applications in relation with advertising is in-depth
examination of product characteristics to enhance product knowledge
as well as brand knowledge. Interactive design of advertising
provides observers with an intense examination of a specific
advertising message and therefore leads to better brand knowledge.
The elaboration likelihood model and the central route to persuasion
strongly support this argumentation. Nevertheless, AR in brand
communication is still in an initial stage and therefore scientific
findings about the impact of AR on information processing and brand
attitude are rare. The aim of this paper is to empirically investigate
the potential of AR applications in combination with traditional print
advertising. To that effect an experimental design with different
levels of interactivity is built to measure the impact of interactivity of
an ad on different variables o advertising effectiveness.
Abstract: In this paper, a desiccant solar unit for air
conditioning and desalination is presented first. Secondly, a dynamic
modelling study of the desiccant wheel is developed. After that, a
simulation study and an experimental investigation of the behaviour
of desiccant wheel are developed. The experimental investigation is
done in the chamber of commerce in Freiburg-Germany. Indeed, the
variations of calculated and measured temperatures and specific
humidity of dehumidified and rejected air are presented where a good
agreement is found when comparing the model predictions with
experimental data under the considered range of operating conditions.
Finally, the study of the compartments of desalination and water
condensation shows that the unit can produce an acceptable quantity
of water at the same time of the air conditioning operation.
Abstract: Historic paths in today's cities are facing the pressure
of the urban development due to the rapid urban growth. Every new
development is tearing the old urban fabric and the socio-economic
character of the historic paths. Furthermore, in some cases historic
paths suffer from negligence and decay. Kom El Dekka historic path
was one of those deteriorated paths in the city of Alexandria, Egypt,
in spite of its high heritage and socio-economic value. Therefore,
there was a need to develop urban regeneration strategies as a part of
a wider sustainable development vision, to handle the situation and
revitalize the path as a livable space in the heart of the city. This
study aims to develop a comprehensive assessment methodology to
evaluate the different values of the path and to create community-oriented
and economic-based analysis methodology for its socio-economic
values. These analysis and assessments provide strategies
for any regeneration action plan for Kom El Dekka historic path.
Abstract: This article considers the problems of economic growth
and Russian energy strategy. Also in this paper, the issues related to
the economic growth prospects of Russian were discussed. Russian
energy strategy without standing Russia`s stature in global energy
markets, at the current production and extraction rates, will not be able
to sustain its own production as well as fulfil its energy strategy.
Indeed, Russia’s energy sector suffers from a chronic lack of
investments which are necessary to modernize its energy supply
system. In recent years, especially since the international financial
crisis, Russia-EU energy cooperation has made substantive progress.
Recently the break-through progress has been made, resulting mainly
from long-term contributing factors between the countries and recent
international economic and political situation changes. Analytical
material presented in the article is intended for a more detailed or
substantive analysis related to foreign economic relations of the
countries and Russia as well.
Abstract: Comparing with prior studies mainly focused on the
effect of a certain event (it may be the initial announcement of bad
news or the repeated announcements of identical bad news) on stock
price, the aim of this study is to explore how investors react to
subsequent bad news with identical content. Empirical results show
that as a result of behavioral pitfalls, investors underreact to the initial
announcement of the bad news (i.e., unknown bad news) and overreact
to the repeated announcements of the identical bad news (i.e., known
bad news).
Abstract: The combination of the properties of graphene oxide
(OG) and PVDF homopolymer makes their combined composite
materials as multifunctional systems with great potential. Knowledge
of the molecular structure is essential for better use. In this work, the
degradation of PVDF polymer exposed to gamma irradiation in
oxygen atmosphere in high dose rate has been studied and compared
to degradation of PVDF/OG composites. The samples were irradiated
with a Co-60 source at constant dose rate, with doses ranging from
100 kGy to 1,000 kGy. In FTIR data shown that the formation of
oxidation products was at the both samples with formation of
carbonyl and hydroxyl groups amongst the most prevalent products
in the pure PVDF samples. In the other hand, the composites samples
exhibit less presence of degradation products with predominant
formation of carbonyl groups, these results also seen in the UV-Vis
analysis. The results show that the samples of composites may have
greater resistance to the irradiation process, since they have less
degradation products than pure PVDF samples seen by spectroscopic
techniques.
Abstract: Elastic scattering of α-particles from 9Be and 11B
nuclei at different alpha energies have been analyzed. Optical model
parameters (OMPs) of α-particles elastic scattering by these nuclei at
different energies have been obtained. In the present calculations, the
real part of the optical potential are derived by folding of nucleonnucleon
(NN) interaction into nuclear matter density distribution of
the projectile and target nuclei using computer code FRESCO. A
density-dependent version of the M3Y interaction (CDM3Y6), which
is based on the G-matrix elements of the Paris NN potential, has been
used. Volumetric integrals of the real and imaginary potential depth
(JR, JW) have been calculated and found to be energy dependent.
Good agreement between the experimental data and the theoretical
predictions in the whole angular range. In double folding (DF)
calculations, the obtained normalization coefficient Nr is in the range
0.70–1.32.
Abstract: Community living adjacent to forests and Protected
Areas, especially in South Asian countries, have a common practice
in extracting resources for their living and livelihoods. This
extraction of resources, because the way it is done, destroys the biophysical
features of the area. Deforestation, wildlife poaching, illegal
logging, unauthorized hill cutting etc. are some of the serious issues
of concern for the sustainability of the natural resources that has a
direct impact on environment and climate as a whole. To ensure
community involvement in conservation initiatives of the state,
community based forest management, commonly known as Comanagement,
has been in practice in 6 South Asian countries. These
are -India, Nepal, Sri Lanka, Pakistan, Bhutan and Bangladesh.
Involving community in forestry management was initiated first in
Bangladesh in 1979 and reached as an effective co-management
approach through a several paradigm shifts. This idea of Comanagement
has been institutionalized through a Government Order
(GO) by the Ministry of Environment and Forests, Government of
Bangladesh on November 23, 2009. This GO clearly defines the
structure and functions of Co-management and its different bodies.
Bangladesh Forest Department has been working in association with
community to conserve and manage the Forests and Protected areas
of Bangladesh following this legal document. Demographically
young people constitute the largest segment of population in
Bangladesh. This group, if properly sensitized, can produce valuable
impacts on the conservation initiatives, both by community and
government. This study traced the major factors that motivate
community youths to work effectively with different tiers of comanagement
organizations in conservation of forests and Protected
Areas of Bangladesh. For the purpose of this study, 3 FGDs were
conducted with 30 youths from the community living around the
Protected Areas of Cox’s bazar, South East corner of Bangladesh,
who are actively involved in Co-management organizations. KII were
conducted with 5 key officials of Forest Department stationed at
Cox’s Bazar. 2 FGDs were conducted with the representatives of 7
Co-management organizations working in Cox’s Bazar region and
approaches of different community outreach activities conducted for
forest conservation by 3 private organizations and Projects have been
reviewed. Also secondary literatures were reviewed for the history
and evolution of Co-management in Bangladesh and six South Asian
countries. This study found that innovative community outreach
activities that are financed by public and private sectors involving
youths and community as a whole have played a pivotal role in
conservation of forests and Protected Areas of the region. This
approach can be replicated in other regions of Bangladesh as well as
other countries of South Asia where Co-Management exists in
practice.
Abstract: Solar water heating is a thermodynamic process of
heating water using sunlight with the help of solar water heater. Thus,
solar water heater is a device used to harness solar energy. In this
paper, a modified solar water heating system (MSWHS) has been
proposed over flat plate collector (FPC) and Evacuated tube collector
(ETC). The modifications include selection of materials other than
glass, and glass wool which are conventionally used for fabricating
FPC and ETC. Some modifications in design have also been
proposed. Its collector is made of double layer of semi-cylindrical
acrylic tubes and fibre reinforced plastic (FRP) insulation base. Water
tank is made of double layer of acrylic sheet except base and north
wall. FRP is used in base and north wall of the water tank. A concept
of equivalent thickness has been utilised for calculating the
dimensions of collector plate, acrylic tube and tank. A thermal model for the proposed design of MSWHS is developed
and simulation is carried out on MATLAB for the capacity of 200L
MSWHS having collector area of 1.6 m2, length of acrylic tubes of
2m at an inclination angle 25° which is taken nearly equal to the
latitude of the given location. Latitude of Allahabad is 24.45° N. The
results show that the maximum temperature of water in tank and tube
has been found to be 71.2°C and 73.3°C at 17:00hr and 16:00hr
respectively in March for the climatic data of Allahabad. Theoretical performance analysis has been carried out by varying
number of tubes of collector, the tank capacity and climatic data for
given months of winter and summer.
Abstract: HMS Industrial Networks AB has been recognized as
one of the most innovative companies in the industrial
communication industry worldwide. The creation of their Anybus
innovation during the 1990s contributed considerably to the
company’s success. From inception, HMS’ employees were
innovating for the purpose of creating new business (the creation
phase). After the Anybus innovation, they began the process of
internationalization (the commercialization phase), which in turn led
them to concentrate on cost reduction, product quality, delivery
precision, operational efficiency, and increasing growth (the growth
phase). As a result of this transformation, performing new radical
innovations have become more complicated. The purpose of our research was to explore the dynamics of
innovation at HMS from the aspect of key actors, activities, and
events, over the three phases, in order to understand what led to the
creation of their Anybus innovation, and why it has become
increasingly challenging for HMS to create new radical innovations
for the future. Our research methodology was based on a longitudinal,
retrospective study from the inception of HMS in 1988 to 2014, a
single case study inspired by the grounded theory approach. We
conducted 47 interviews and collected 1 024 historical documents for
our research. Our analysis has revealed that HMS’ success in creating the
Anybus, and developing a successful business around the innovation,
was based on three main capabilities – cultivating customer relations
on different managerial and organizational levels, inspiring business
relations, and balancing complementary human assets for the purpose
of business creation. The success of HMS has turned the management’s attention away
from past activities of key actors, of their behavior, and how they
influenced and stimulated the creation of radical innovations.
Nowadays, they are rhetorically focusing on creativity and
innovation. All the while, their real actions put emphasis on growth,
cost reduction, product quality, delivery precision, operational
efficiency, and moneymaking. In the process of becoming an
international company, HMS gradually refocused. In so doing they
became profitable and successful, but they also forgot what made
them innovative in the first place. Fortunately, HMS’ management
has come to realize that this is the case and they are now in search of
recapturing innovation once again. Our analysis indicates that HMS’ management is facing several
barriers to innovation related path dependency and other lock-in
phenomena. HMS’ management has been captured, trapped in their
mindset and actions, by the success of the past. But now their future has to be secured, and they have come to realize that moneymaking is
not everything. In recent years, HMS’ management have begun to
search for innovation once more, in order to recapture their past
capabilities for creating radical innovations. In order to unlock their
managerial perceptions of customer needs and their counter-innovation
driven activities and events, to utilize the full potential of
their employees and capture the innovation opportunity for the future.
Abstract: The rapid growth of the human population and the
environmental degradation associated with increased consumption of
resources raises concerns on sustainability. Social sustainability
constitutes one of the three dimensions of sustainability together with
environmental and economic dimensions. Even though there is not an
agreement on what social sustainability consists of, it is a well known
fact that it necessitates user participation. The fore, this study aims to
observe and analyze the role of user participation on social
sustainability. In this paper, the links between user participation and indicators of
social sustainability have been searched. In order to achieve this, first
of all a literature review on social sustainability has been done;
accordingly, the information obtained from researches has been used
in the evaluation of the projects conducted in the developing
countries considering user participation. These examples are taken as
role models with pros and cons for the development of the checklist
for the evaluation of the case studies. Furthermore, a case study over
the post earthquake residential settlements in Turkey have been
conducted. The case study projects are selected considering different building
scales (differing number of residential units), scale of the problem
(post-earthquake settlements, rehabilitation of shanty dwellings) and
the variety of users (differing socio-economic dimensions). Decisionmaking,
design, building and usage processes of the selected projects
and actors of these processes have been investigated in the context of
social sustainability. The cases include: New Gourna Village by
Hassan Fathy, Quinta Monroy dwelling units conducted in Chile by
Alejandro Aravena and Beyköy and Beriköy projects in Turkey
aiming to solve the problem of housing which have appeared after the
earthquake happened in 1999 have been investigated. Results of the
study possible links between social sustainability indicators and user
participation and links between user participation and the
peculiarities of place. Results are compared and discussed in order to find possible
solutions to form social sustainability through user participation.
Results show that social sustainability issues depend on communities'
characteristics, socio-economic conditions and user profile but user
participation has positive effects on some social sustainability
indicators like user satisfaction, a sense of belonging and social
stability.
Abstract: Strategic investment decisions are characterized by
high innovation potential and long-term effects on the
competitiveness of enterprises. Due to the uncertainty and risks
involved in this complex decision making process, the need arises for
well-structured support activities. A method that considers cost and
the long-term added value is the cost-benefit effectiveness estimation.
One of those methods is the “profitability estimation focused on
benefits – PEFB”-method developed at the Institute of Management
Cybernetics at RWTH Aachen University. The method copes with
the challenges associated with strategic investment decisions by
integrating long-term non-monetary aspects whilst also mapping the
chronological sequence of an investment within the organization’s
target system. Thus, this method is characterized as a holistic
approach for the evaluation of costs and benefits of an investment.
This participation-oriented method was applied to business
environments in many workshops. The results of the workshops are a
library of more than 96 cost aspects, as well as 122 benefit aspects.
These aspects are preprocessed and comparatively analyzed with
regards to their alignment to a series of risk levels. For the first time,
an accumulation and a distribution of cost and benefit aspects
regarding their impact and probability of occurrence are given. The
results give evidence that the PEFB-method combines precise
measures of financial accounting with the incorporation of benefits.
Finally, the results constitute the basics for using information
technology and data science for decision support when applying
within the PEFB-method.
Abstract: The study was meant to identify the impediments to
female sports management and participation in the selected colleges.
Seven colleges of education in the south west parts of the country
were selected for the study. A total of one hundred and five subjects
were sampled to supply data. Only one hundred adequately
completed and returned, copies of the questionnaire were used for
data analysis. The collected data were analysed descriptively. The
result of the study showed that inadequate fund, personnel, facilities
equipment, supplies, management of sports, supervision and coaching
were some of the impediments to female sports management and
participation. Athletes were not encouraged to participate. Based on
the findings, it was recommended that the government should come
to the aid of the colleges by providing fund and other needs that will
make sports attractive for enhanced participation.
Abstract: The layered structure LiNi1/3Co1/3Mn1/3-xAlxO2 (x = 0 ~
0.04) series cathode materials were synthesized by a carbonate
co-precipitation method, followed by a high temperature calcination
process. The influence of Al substitution on the microstructure and
electrochemical performances of the prepared materials was
investigated by X-Ray diffraction (XRD), scanning electron
microscopy (SEM), and galvanostatic charge/discharge test. The
results show that the LiNi1/3Co1/3Mn1/3-xAlxO2 has a well-ordered
hexagonal α-NaFeO2 structure. Although the discharge capacity of
Al-doped samples decreases as x increases,
LiNi1/3Co1/3Mn1/3-0.02Al0.02O2 exhibits superior capacity retention at
high voltage (4.6 V). Therefore, LiNi1/3Co1/3Mn1/3-0.02Al0.02O2 is a
promising material for “green” vehicles.
Abstract: Recently developed cooperative diversity scheme
enables a terminal to get transmit diversity through the support of other
terminals. However, most of the introduced cooperative schemes have
a common fault of decreased transmission rate because the destination
should receive the decodable compositions of symbols from the source
and the relay. In order to achieve high data rate, we propose a
cooperative scheme that employs hierarchical modulation. This
scheme is free from the rate loss and allows seamless cooperative
communication.