Abstract: Using the quantum hydrodynamic (QHD) model the
nonlinear properties of ion-acoustic waves in are lativistically
degenerate quantum plasma is investigated by deriving a nonlinear
Spherical Kadomtsev–Petviashvili (SKP) equation using the
standard reductive perturbation method equation. It was found that
the electron degeneracy parameter significantly affects the linear
and nonlinear properties of ion-acoustic waves in quantum plasma.
Abstract: This article proposes a new method for application in
communication circuit systems that increase efficiency, PAE, output
power and gain in the circuit. The proposed method is based on a
combination of switching class-E and class-J and has been termed
class-EJ. This method was investigated using both theory and
simulation to confirm ∼72% PAE and output power of >39dBm. The
combination and design of the proposed power amplifier accrues gain
of over 15dB in the 2.9 to 3.5GHz frequency bandwidth. This circuit
was designed using MOSFET and high power transistors. The loadand
source-pull method achieved the best input and output networks
using lumped elements. The proposed technique was investigated for
fundamental and second harmonics having desirable amplitudes for
the output signal.
Abstract: The potential neuroprotective effect of Phyllantus
nuriri against Fe2+ and sodium nitroprusside (SNP) induced oxidative
stress in mitochondria of rats brain was evaluated. Cellular viability
was assessed by MTT reduction, reactive oxygen species (ROS)
generation was measured using the probe 2,7-dichlorofluoresce
indiacetate (DCFH-DA). Glutathione content was measured using
dithionitrobenzoic acid (DTNB). Fe2+ (10μM) and SNP (5μM)
significantly decreased mitochondrial activity, assessed by MTT
reduction assay, in a dose-dependent manner, this occurred in parallel
with increased glutathione oxidation, ROS production and lipid
peroxidation end-products (thiobarbituric acid reactive substances,
TBARS). The co-incubation with methanolic extract of Phyllantus
nuriri (10-200 μg/ml) reduced the disruption of mitochondrial
activity, gluthathione oxidation, ROS production as well as the
increase in TBARS levels caused by both Fe2+ and SNP in a dose
dependent manner. HPLC analysis of the extract revealed the
presence of gallic acid (20.540.01), caffeic acid (7.930.02), rutin
(25.310.05), quercetin (31.280.03) and kaemferol (14.360.01).
This result suggests that these phytochemicals account for the
protective actions of P. niruri against Fe2+ and SNP -induced
oxidative stress. Our results show that P. nuriri consist important
bioactive molecules in the search for an improved therapy against the
deleterious effects of Fe2+, an intrinsic producer of reactive oxygen
species (ROS), that leads to neuronal oxidative stress and
neurodegeneration.
Abstract: This paper investigates the benefits of deliberately
unbalancing both operation time means (MTs) and unreliability
(failure and repair rates) for non-automated production lines. The
lines were simulated with various line lengths, buffer capacities,
degrees of imbalance and patterns of MT and unreliability imbalance.
Data on two performance measures, namely throughput (TR) and
average buffer level (ABL) were gathered, analyzed and compared to
a balanced line counterpart. A number of conclusions were made
with respect to the ranking of configurations, as well as to the
relationships among the independent design parameters and the
dependent variables. It was found that the best configurations are a
balanced line arrangement and a monotone decreasing MT order,
coupled with either a decreasing or a bowl unreliability configuration,
with the first generally resulting in a reduced TR and the second
leading to a lower ABL than those of a balanced line.
Abstract: The present study was carried out to investigate the
effect of alloying elements and thermo-mechanical treatment (TMT)
i.e. hot rolling and forging with different reduction ratios on the
hardness (HV) and impact toughness (J) of heat-treated low alloy
steels. An understanding of the combined effect of TMT and alloying
elements and by measuring hardness, impact toughness, resulting
from different heat treatment following TMT of the low alloy steels,
it is possible to determine which conditions yielded optimum
mechanical properties and high strength to weight ratio.
Experimental Correlations between hot work reduction ratio,
hardness and impact toughness for thermo-mechanically heat treated
low alloy steels are analyzed quantitatively, and both regression and
mathematical hardness and impact toughness models are developed.
Abstract: This paper proposes techniques like MT CMOS,
POWER GATING, DUAL STACK, GALEOR and LECTOR to
reduce the leakage power. A Full Adder has been designed using
these techniques and power dissipation is calculated and is compared
with general CMOS logic of Full Adder.
Simulation results show the validity of the proposed techniques is
effective to save power dissipation and to increase the speed of
operation of the circuits to a large extent.
Abstract: This study is about the structural transformations of
aluminium examining with the Dynamic Mechanical Thermal
Analyzer (DMTA). It is a faster and simpler measuring method to
make consequence about the metal’s structural transformations. The
device measures the changing of the mechanical characteristics
depending on the heating rate, and concludes certain transformations.
This measuring method fast and shows clean-cut results comparing
the conventional ways.
Applying polymer measuring devices for metal investigations is
not widespread method. One of the adaptable ways is shown in this
study. The article compares the results of the small specimen test and
the DMTA method, considering the temperature and the forming
dependence of recrystallization temperature.
Abstract: Machining of hard materials is a recent technology for
direct production of work-pieces. The primary challenge in
machining these materials is selection of cutting tool inserts which
facilitates an extended tool life and high-precision machining of the
component. These materials are widely for making precision parts for
the aerospace industry. Nickel-based alloys are typically used in
extreme environment applications where a combination of strength,
corrosion resistance and oxidation resistance material characteristics
are required. The present paper reports the theoretical and
experimental investigations carried out to understand the influence of
machining parameters on the response parameters. Considering the
basic machining parameters (speed, feed and depth of cut) a study has
been conducted to observe their influence on material removal rate,
surface roughness, cutting forces and corresponding tool wear.
Experiments are designed and conducted with the help of Central
Composite Rotatable Design technique. The results reveals that for a
given range of process parameters, material removal rate is favorable
for higher depths of cut and low feed rate for cutting forces. Low feed
rates and high values of rotational speeds are suitable for better finish
and higher tool life.
Abstract: Interaction of Schiff base complexes of Iron and
Manganese: Iron [N, N’ Bis (5- (triphenyl phosphonium methyl)
salicylidene) -1, 2 ethanediamine) chloride, [Fe Salen]Cl; Manganese
[N, N’ Bis (5- (triphenyl phosphonium methyl) salicylidene) -1, 2
ethanediamine) acetate, were investigated by spectroscopic and
isothermal titration calorimetry techniques (ITC).
The absorbance spectra of complexes have shown hyper and
hypochromism in the presence of DNA that is indication of
interaction of complexes with DNA. The linear dichroism (LD)
measurements confirmed the bending of DNA in the presence of
complexes.
Furthermore, Isothermal titration calorimetry experiments
approved that complexes bound to DNA on the base of both
electrostatic and hydrophobic interactions. More, ITC profile exhibits
the existence of two binding phases for the complexes. Antibacterial
activity of ligand and complexes were tested in vitro to evaluate their
activity against the gram positive and negative bacteria.
Abstract: The object of the present paper is to investigate several
general families of bilinear and bilateral generating functions with
different argument for the Gauss’ hypergeometric polynomials.
Abstract: The ultrasound imaging is very popular to diagnosis
the disease because of its non-invasive nature. The ultrasound
imaging slowly produces low quality images due to the presence of
spackle noise and wave interferences. There are several algorithms to
be proposed for the segmentation of ultrasound carotid artery images
but it requires a certain limit of user interaction. The pixel in an
image is highly correlated so the spatial information of surrounding
pixels may be considered in the process of image segmentation which
improves the results further. When data is highly correlated, one pixel
may belong to more than one cluster with different degree of
membership. There is an important step to computerize the evaluation
of arterial disease severity using segmentation of carotid artery lumen
in 2D and 3D ultrasonography and in finding vulnerable
atherosclerotic plaques susceptible to rupture which can cause stroke.
Abstract: Social Media (SM) is websites increasingly popular
and built to allow people to express themselves and to interact
socially with others. Most SMT are dominated by youth particularly
College students. The proliferation of popular social media tools,
which can accessed from any communication devices has become
pervasive in the lives of today’s student life. Connecting traditional
education to social media tools are a relatively new era and any
collaborative tool could be used for learning activities. This study
focuses (i) how the social media tools are useful for the learning
activities of the students of faculty of medicine in King Khalid
University (ii) whether the social media affects the collaborative
learning with interaction among students, among course instructor,
their engagement, perceived ease of use and perceived ease of
usefulness (TAM) (iii) overall, the students satisfy with this
collaborative learning through Social media.
Abstract: Although, arsenic trioxide has been the subject of
toxicological research, in vitro cytotoxicity and genotoxicity studies
using relevant cell models and uniform methodology are not well
elucidated. Hence, the aim of the present study was to evaluate the
cytotoxicity and genotoxicity induced by arsenic trioxide in human
keratinocytes (HaCaT) using the MTT [3-(4, 5-dimethylthiazol-2-yl)-
2,5-diphenyltetrazolium bromide] and alkaline single cell gel
electrophoresis (Comet) assays, respectively. Human keratinocytes
were treated with different doses of arsenic trioxide for 4 h prior to
cytogenetic assessment. Data obtained from the MTT assay indicated
that arsenic trioxide significantly reduced the viability of HaCaT cells
in a dose-dependent manner, showing an IC50 value of 34.18 ± 0.6
μM. Data generated from the comet assay also indicated a significant
dose-dependent increase in DNA damage in HaCaT cells associated
with arsenic trioxide exposure. We observed a significant increase in
comet tail length and tail moment, showing an evidence of arsenic
trioxide -induced genotoxic damage in HaCaT cells. This study
confirms that the comet assay is a sensitive and effective method to
detect DNA damage caused by arsenic.
Abstract: Background: The effectiveness of mirror therapy
(MT) has been investigated in acute hemiplegia. The present study
examines whether MT, given during chronic stroke, was more
effective in promoting motor recovery of the lower extremity and
walking speed than standard rehabilitation alone. Methods: The study
enrolled 30 patients with chronic stroke. Fifteen patients each were
assigned to the treatment group and the control group. All patients
received a conventional rehabilitation program for a 4-week period.
In addition to this rehabilitation program, patients in the treatment
group received mirror therapy for 4 weeks, 5 days a week. Main
measures: Passive ankle joint dorsiflexion range of motion, gait
speed, Brunnstrom stages of motor recovery, plantar flexor muscle
tone by Modified Ashworth Scale. Results: No significant difference
was found in the outcome measures among groups before treatment.
When compared with standard rehabilitation, mirror therapy
improved Ankle ROM, Brunnstrom stages and waking speed
(p < 0.05). However, there were no significant differences between
two groups on MAS (P > 0.05).Conclusion: Mirror therapy combined
with a conventional stroke rehabilitation program enhances lowerextremity
motor recovery and walking speed in chronic stroke
patients.
Abstract: The investigation in the present paper is to obtain
certain types of relations for the well known hypergeometric functions
by employing the technique of fractional derivative and integral.
Abstract: This paper presents the details of a numerical study of
buckling and post buckling behaviour of laminated carbon fiber
reinforced plastic (CFRP) thin-walled cylindrical shell under axial
compression using asymmetric meshing technique (AMT) by
ABAQUS. AMT is considered to be a new perturbation method to
introduce disturbance without changing geometry, boundary
conditions or loading conditions. Asymmetric meshing affects both
predicted buckling load and buckling mode shapes. Cylindrical shell
having lay-up orientation [0^o/+45^o/-45^o/0^o] with radius to thickness
ratio (R/t) equal to 265 and length to radius ratio (L/R) equal to 1.5 is
analysed numerically. A series of numerical simulations
(experiments) are carried out with symmetric and asymmetric
meshing to study the effect of asymmetric meshing on predicted
buckling behaviour. Asymmetric meshing technique is employed in
both axial direction and circumferential direction separately using
two different methods, first by changing the shell element size and
varying the total number elements, and second by varying the shell
element size and keeping total number of elements constant. The
results of linear analysis (Eigenvalue analysis) and non-linear
analysis (Riks analysis) using symmetric meshing agree well with
analytical results. The results of numerical analysis are presented in
form of non-dimensional load factor, which is the ratio of buckling
load using asymmetric meshing technique to buckling load using
symmetric meshing technique. Using AMT, load factor has about 2%
variation for linear eigenvalue analysis and about 2% variation for
non-linear Riks analysis. The behaviour of load end-shortening curve
for pre-buckling is same for both symmetric and asymmetric meshing
but for asymmetric meshing curve behaviour in post-buckling
becomes extraordinarily complex. The major conclusions are:
different methods of AMT have small influence on predicted
buckling load and significant influence on load displacement curve
behaviour in post buckling; AMT in axial direction and AMT in
circumferential direction have different influence on buckling load
and load displacement curve in post-buckling.
Abstract: Complexation of anthocyanins to mimic natural
copigmentation process was investigated. Cyanidin-rich extracts from
Zea mays L. ceritina Kulesh. and delphinidin-rich extracts from
Clitoria ternatea L. were used to form 4 anthocyanin complexes,
AC1, AC2, AC3 and AC4, in the presence of several polyphenols and
a trace metal. Characterizations of the ACs were conducted by UV,
FTIR, DSC/TGA and morphological observations. Bathochromic
shifts of the UV spectra of 4 formulas of ACs were observed at peak
wavelengths of about 510-620 nm by 10 nm suggesting complex
formation. FTIR spectra of the ACs indicate shifts of peaks from
1,733 cm-1 to 1,696 cm-1 indicating interactions and a decrease in the
peak areas within the wavenumber of 3,400-3,500 cm-1 indicating
changes in hydrogen bonding. Thermal analysis of all of the ACs
suggests increases in melting temperature after complexation. AC
with the highest melting temperature was morphologically observed
by SEM and TEM to be crystal-like particles within a range of 50 to
200 nm. Particle size analysis of the AC by laser diffraction gave a
range of 50-600 nm, indicating aggregation. This AC was shown to
have no cytotoxic effect on cultured HGEPp0.5 and HGF (all p>
0.05) by MTT. Therefore, complexation of anthocyanins was simple
and self-assembly process, potentially resulting in nanosized particles
of anthocyanin complex.
Abstract: Anthocyanins are natural pigments with effective UV
protection but their topical use could be limited due to their
physicochemical characteristics. An attempt to overcome such
limitations by complexation of 2 major anthocyanin-rich sources, C.
ternatea and Z. mays, has potentiated its use as topical antiinflammatory.
Cell studies indicate no cytotoxicity of the
anthocyanin complex (AC) up to 1 mg/ml tested in HaCaT and
human fore head fibroblasts by MTT. Croton oil-induced ear edema
in Wistar rats suggests an effective dose of 5 mg/cm2 of AC as a
topical anti-inflammatory in comparison to 0.5 mg/cm2 of
fluocinolone acetonide. Niosomal encapsulation of the AC
significantly prolonged the anti-inflammatory activity particularly at
8 h after topical application (p = 0.0001). The AC was not cytotoxic
and its anti-inflammatory and activity was dose-dependent and
prolonged by niosomal encapsulation. It has also shown to promote
collagen type 1 production in cell culture. Thus, AC could be a
potential candidate for topical anti-inflammatory agent from natural
resources.
Abstract: Vertical Handover(VHO) among different
communication technologies ensuring uninterruption and service
continuity is one of the most important performance parameter in
Heterogenous networks environment. In an integrated Universal
Mobile Telecommunicatin System(UMTS) and Wireless Local
Area Network(WLAN), WLAN is given an inherent priority over
UMTS because of its high data rates with low cost. Therefore
mobile users want to be associated with WLAN maximum of the
time while roaming, to enjoy best possible services with low cost.
That encourages reduction of number of VHO. In this work the
reduction of number of VHO with respect to varying number of
WLAN Access Points(APs) in an integrated UMTS and WLAN
network is investigated through simulation to provide best possible
cost effective service to the users. The simulation has been carried
out for an area (7800 × 9006)m2 where COST-231 Hata model
and 3GPP (TR 101 112 V 3.1.0) specified models are used for
WLAN and UMTS path loss models respectively. The handover
decision is triggered based on the received signal level as compared
to the fade margin. Fade margin gives a probabilistic measure of
the reliability of the communication link. A relationship between
number of WLAN APs and the number of VHO is also established
in this work.
Abstract: The Roma (Gypsies) is a transnational minority with a
high degree of consanguineous marriages. Similar to other
genetically isolated founder populations, the Roma harbor a number
of unique or rare genetic disorders. This paper discusses about a rare
form of Charcot-Marie-Tooth disease – type 4G (CMT4G), also
called Hereditary Motor and Sensory Neuropathy type Russe, an
autosomal recessive disease caused by mutation private to Roma
characterized by abnormally increased density of non-myelinated
axons. CMT4G was originally found in Bulgarian Roma and in 2009
two putative causative mutations in the HK1 gene were identified.
Since then, several cases were reported in Roma families mainly
from Bulgaria and Spain. Here we present a Slovak Roma family in
which CMT4G was diagnosed on the basis of clinical examination
and genetic testing. This case is a further proof of the role of the HK1
gene in pathogenesis of the disease. It confirms that mutation in the
HK1 gene is a common cause of autosomal recessive CMT disease in
Roma and should be considered as a common part of a diagnostic
procedure.