Abstract: This study aimed to assess the in vitro effects of different concentrations of the Viscum album extract on the motility, viability, and reactive oxygen species (ROS) production by rabbit spermatozoa during different time periods (0, 2, and 8h). Spermatozoa motility was assessed by using the CASA (Computer aided sperm analysis) system. Cell viability was evaluated by using the metabolic activity MTT assay, and the luminol-based luminometry was applied to quantify the ROS formation. The CASA analysis revealed that low Viscum concentrations were able to prevent a rapid decline of spermatozoa motility, especially in the case of concentrations ranging between 1 and 5 µg/mL (P
Abstract: Land-cover maps were important for many scientific, ecological and land management purposes and during the last decades, rapid decrease of soil fertility was observed to be due to land use practices such as rice cultivation. High-precision land-cover maps are not yet available in the area which is important in an economy management. To assure accurate mapping of land cover to provide information, remote sensing is a very suitable tool to carry out this task and automatic land use and cover detection. The study did not only provide high precision land cover maps but it also provides estimates of rice production area that had undergone chemical degradation due to fertility decline. Land-cover were delineated and classified into pre-defined classes to achieve proper detection features. After generation of Land-cover map, of high intensity of rice cultivation, soil fertility degradation assessment in rice production area due to fertility decline was created to assess the impact of soils used in agricultural production. Using Simple spatial analysis functions and ArcGIS, the Land-cover map of Municipality of Quezon in Nueva Ecija, Philippines was overlaid to the fertility decline maps from Land Degradation Assessment Philippines- Bureau of Soils and Water Management (LADA-Philippines-BSWM) to determine the area of rice crops that were most likely where nitrogen, phosphorus, zinc and sulfur deficiencies were induced by high dosage of urea and imbalance N:P fertilization. The result found out that 80.00 % of fallow and 99.81% of rice production area has high soil fertility decline.
Abstract: The abiotic elicitation is one of the methods for
increasing the secondary metabolites production in plant tissue
cultures and it seems to be more effective than traditional strategies.
This study verified the use of silver nitrate as elicitor to enhance
flavonolignans and flavonoid taxifolin production in suspension
culture of Sylibum marianum (L.) Gaertn. Silver nitrate in various
concentrations (5.887.10-3 mol/L, 5.887.10-4 mol/L, 5.887.10-5
mol/L) was used as elicitor. The content of secondary metabolites in
cell suspension cultures was determined by high performance liquid
chromatography. The samples were taken after 6, 12, 24, 48, 72 and
168 hours of treatment. The highest content of taxifolin production
(2.2 mg.g-1) in cell suspension culture of Silybum marianum (L.)
Gaertn. was detected after silver nitrate (5.887.10-4 mol/L) treatment
and 72 h application. Flavonolignans such as silybinA, silybin B,
silydianin, silychristin, isosilybin A, isosilybin B were not produced
by cell suspension culture of S. marianum after elicitor treatment.
Our results show that the secondarymetabolites could be released
from S. marianum cells into the nutrient medium by changed
permeability of cell wall.
Abstract: Experiments were performed to investigate the effects of roughness on the reattachment and redevelopment regions over a 12 mm forward facing step (FFS) in an open channel flow. The experiments were performed over an upstream smooth wall and a smooth FFS, an upstream wall coated with sandpaper 36 grit and a smooth FFS and an upstream rough wall produced from sandpaper 36 grit and a FFS coated with sandpaper 36 grit. To investigate only the wall roughness effects, Reynolds number, Froude number, aspect ratio and blockage ratio were kept constant. Upstream profiles showed reduced streamwise mean velocities close to the rough wall compared to the smooth wall, but the turbulence level was increased by upstream wall roughness. The reattachment length for the smooth-smooth wall experiment was 1.78h; however, when it is replaced with rough-smooth wall the reattachment length decreased to 1.53h. It was observed that the upstream roughness increased the physical size of contours of maximum turbulence level; however, the downstream roughness decreased both the size and magnitude of contours in the vicinity of the leading edge of the step. Quadrant analysis was performed to investigate the dominant Reynolds shear stress contribution in the recirculation region. The Reynolds shear stress and turbulent kinetic energy profiles after the reattachment showed slower recovery compared to the streamwise mean velocity, however all the profiles fairly collapse on their corresponding upstream profiles at x/h = 60. It was concluded that to obtain a complete collapse several more streamwise distances would be required.
Abstract: Learning outcomes of a course (CLOs) and the abilities at the time of graduation referred to as Student Outcomes (SOs) are required to be assessed for ABET accreditation. A question in an assessment must target a CLO as well as an SO and must represent a required level of competence. This paper presents the idea of an Expert System (ES) to select a proper question to satisfy ABET accreditation requirements. For ES implementation, seven attributes of a question are considered including the learning outcomes and Bloom’s Taxonomy level. A database contains all the data about a course including course content topics, course learning outcomes and the CLO-SO relationship matrix. The knowledge base of the presented ES contains a pool of questions each with tags of the specified attributes. Questions and the attributes represent expert opinions. With implicit rule base the inference engine finds the best possible question satisfying the required attributes. It is shown that the novel idea of such an ES can be implemented and applied to a course with success. An application example is presented to demonstrate the working of the proposed ES.
Abstract: The effect of upstream surface roughness over a
smooth forward facing step in an open channel was investigated
using a particle image velocimetry technique. Three different
upstream surface topographies consisting of hydraulically smooth
wall, sandpaper 36 grit and sand grains were examined. Besides the
wall roughness conditions, all other upstream flow characteristics
were kept constant. It was also observed that upstream roughness
decreased the approach velocity by 2% and 10% but increased the
turbulence intensity by 14% and 35% at the wall-normal distance
corresponding to the top plane of the step compared to smooth
upstream. The results showed that roughness decreased the
reattachment lengths by 14% and 30% compared to smooth upstream.
Although the magnitudes of maximum positive and negative
Reynolds shear stress in separated and reattached region were 0.02Ue
for all the cases, the physical size of both the maximum and
minimum contour levels were decreased by increasing upstream
roughness.
Abstract: We present an approach to triangle mesh simplification
designed to be executed on the GPU. We use a quadric error metric
to calculate an error value for each vertex of the mesh and order all
vertices based on this value. This step is followed by the parallel
removal of a number of vertices with the lowest calculated error
values. To allow for the parallel removal of multiple vertices we use
a set of per-vertex boundaries that prevent mesh foldovers even when
simplification operations are performed on neighbouring vertices. We
execute multiple iterations of the calculation of the vertex errors,
ordering of the error values and removal of vertices until either a
desired number of vertices remains in the mesh or a minimum error
value is reached. This parallel approach is used to speed up the
simplification process while maintaining mesh topology and avoiding
foldovers at every step of the simplification.
Abstract: The right to basic sanitation, was elevated to the
category of fundamental right by the Constitution of 1988 to protect
the ecologically balanced environment, ensuring social rights to
health and adequate housing and put the dignity of the human person
as the foundation of the Brazilian Democratic State. Before their
essentiality to humans, this article seeks to understand why universal
access to basic sanitation is a goal so difficult to achieve in Brazil.
Therefore, this research uses the deductive and analytical method.
Given the nature of the research literature, research techniques were
centered in specialized books on the subject, journals, theses and
dissertations, laws, relevant law case and raising social indicators
relating to the theme. The relevance of the topic stems, among other
things, the fact that sanitation services are essential for a dignified
life, i.e., everyone is entitled to the maintenance of the necessary
existence conditions are satisfied. However, the effectiveness of this
right is undermined in society, since Brazil has huge deficit in
sanitation services, denying thus a worthy life to most of the
population. Thus, it can be seen that the provision of water and
sewage services in Brazil is still characterized by a large imbalance,
since the municipalities with lower population index have greater
disability in the sanitation service. The truth is that the precariousness
of water and sewage services in Brazil is still very concentrated in the
North and Northeast regions, limiting the effective implementation of
the Law 11.445/2007 in the country. Therefore, there is urgent need
for a positive service by the State in the provision of sanitation
services in order to prevent and control disease, improve quality of
life and productivity of individuals, besides preventing contamination
of water resources. More than just social and economic necessity,
there is a government duty to implement such services. In this sense,
given the current scenario, to achieve universal access to basic
sanitation imposes many hurdles. These are mainly in the field of
properly formulated and implemented public policies, i.e., it requires
an excellent institutional organization, management services,
strategic planning, social control, in order to provide answers to
complex challenges.
Abstract: In this paper, we provided a literature survey on the
artificial stock problem (ASM). The paper began by exploring the
complexity of the stock market and the needs for ASM. ASM
aims to investigate the link between individual behaviors (micro
level) and financial market dynamics (macro level). The variety of
patterns at the macro level is a function of the AFM complexity. The
financial market system is a complex system where the relationship
between the micro and macro level cannot be captured analytically.
Computational approaches, such as simulation, are expected to
comprehend this connection. Agent-based simulation is a simulation
technique commonly used to build AFMs. The paper proceeds by
discussing the components of the ASM. We consider the roles
of behavioral finance (BF) alongside the traditionally risk-averse
assumption in the construction of agent’s attributes. Also, the
influence of social networks in the developing of agents interactions is
addressed. Network topologies such as a small world, distance-based,
and scale-free networks may be utilized to outline economic
collaborations. In addition, the primary methods for developing
agents learning and adaptive abilities have been summarized.
These incorporated approach such as Genetic Algorithm, Genetic
Programming, Artificial neural network and Reinforcement Learning.
In addition, the most common statistical properties (the stylized facts)
of stock that are used for calibration and validation of ASM are
discussed. Besides, we have reviewed the major related previous
studies and categorize the utilized approaches as a part of these
studies. Finally, research directions and potential research questions
are argued. The research directions of ASM may focus on the macro
level by analyzing the market dynamic or on the micro level by
investigating the wealth distributions of the agents.
Abstract: Evidence shows that start-ups success is positively
correlated with the launch of the first product. However, new ventures
are seldom able to acquire abundant resources for new product
development (NPD), which means that entrepreneurs may depend on
personal creativity instead of physical investments to achieve and
accelerate innovation speed. This study accentuates the role of
entrepreneurial bricolage, which defined as making do by applying
combinations of the resources at hand to new problems and
opportunities, in the relations of creative self-efficacy and innovation
speed. This study uses the multiple regression analysis to test the
hypotheses in a sample of 203 start-ups operating in various creative
markets in Taiwan. Results reveal that creative self-efficacy is
positively and directly associated with innovation speed, whereas
entrepreneurial bricolage plays a full mediator. These findings offer
important theoretical and practical implications.
Abstract: Knowledge of bone mechanical properties is important
for bone substitutes design and fabrication, and more efficient
prostheses development. The aim of this study is to characterize the
viscoelastic behavior of bone specimens, through stress relaxation
and fatigue tests performed to trabecular bone samples from bovine
femoral heads. Relaxation tests consisted on preloading the samples
at five different magnitudes and evaluate them for 1020 seconds,
adjusting the results to a KWW mathematical model. Fatigue tests
consisted of 700 load cycles and analyze their status at the end of the
tests. As a conclusion we have that between relaxation stress and
each preload there is linear relation and for samples with initial
Young´s modulus greater than 1.5 GPa showed no effects due fatigue
test loading cycles.
Abstract: In the present work, Electrochemical Impedance
Spectrocopy (EIS) is applied to study the transport of different metal
cations through a cation-exchange membrane. This technique enables
the identification of the ionic-transport characteristics and to
distinguish between different transport mechanisms occurring at
different current density ranges. The impedance spectra are
dependent on the applied dc current density, on the type of cation and
on the concentration.
When the applied dc current density increases, the diameter of the
impedance spectra loops increases because all the components of
membrane system resistance increase. The diameter of the impedance
plots decreases in the order of Na(I), Ni(II) and Cr(III) due to the
increased interactions between the negatively charged sulfonic
groups of the membrane and the cations with greater charge. Nyquist
plots are shifted towards lower values of the real impedance, and its
diameter decreases with the increase of concentration due to the
decrease of the solution resistance.
Abstract: Pipa is one of the most important Chinese traditional
plucked instruments, but its directivity has never been measured
systematically. In western, directivity of loudness for western
instruments is deeply researched through analysis of sound pressure
level, whereas the directivity of timbre is seldom studied. In this paper,
a new method for directivity of timbre was proposed, and horizontal
directivity patterns of loudness and timbre of Pipa were measured.
Directivity of Pipa radiation was measured in an anechoic room. The
sound of Pipa played by a musician was recorded simultaneously by
32 microphones with Pipa in the center. The measuring results were
examined through listening test. According to the measurement of
Pipa directivity radiation, we put forward the best localization of Pipa
in the Chinese traditional orchestra and the optimal recording region.
Abstract: This work introduces a simple device designed to
perform in-situ direct shear and sinkage tests on granular materials
as sand, clays, or regolith. It consists of a box nested within a larger
box. Both have open bottoms, allowing them to be lowered into the
material. Afterwards, two rotating plates on opposite sides of the
outer box will rotate outwards in order to clear regolith on either
side, providing room for the inner box to move relative to the plates
and perform a shear test without the resistance of the surrounding
soil. From this test, Coulomb parameters, including cohesion and
internal friction angle, as well as, Bekker parameters can be inferred.
This device has been designed for a laboratory setting, but with few
modifications, could be put on the underside of a rover for use in
a remote location. The goal behind this work is to ultimately create
a compact, but accurate measuring tool to put onto a rover or any
kind of exploratory vehicle to test for regolith properties of celestial
bodies.
Abstract: Chemical Reaction Optimization (CRO) is an
optimization metaheuristic inspired by the nature of chemical
reactions as a natural process of transforming the substances from
unstable to stable states. Starting with some unstable molecules with
excessive energy, a sequence of interactions takes the set to a state of
minimum energy. Researchers reported successful application of the
algorithm in solving some engineering problems, like the quadratic
assignment problem, with superior performance when compared with
other optimization algorithms. We adapted this optimization
algorithm to the Printed Circuit Board Drilling Problem (PCBDP)
towards reducing the drilling time and hence improving the PCB
manufacturing throughput. Although the PCBDP can be viewed as
instance of the popular Traveling Salesman Problem (TSP), it has
some characteristics that would require special attention to the
transactions that explore the solution landscape. Experimental test
results using the standard CROToolBox are not promising for
practically sized problems, while it could find optimal solutions for
artificial problems and small benchmarks as a proof of concept.
Abstract: The Smart Help for persons with disability (PWD) is a
part of the project SMARTDISABLE which aims to develop relevant
solution for PWD that target to provide an adequate workplace
environment for them. It would support PWD needs smartly through
smart help to allow them access to relevant information and
communicate with other effectively and flexibly, and smart editor
that assist them in their daily work. It will assist PWD in knowledge
processing and creation as well as being able to be productive at the
work place. The technical work of the project involves design of a
technological scenario for the Ambient Intelligence (AmI) - based
assistive technologies at the workplace consisting of an integrated
universal smart solution that suits many different impairment
conditions and will be designed to empower the Physically disabled
persons (PDP) with the capability to access and effectively utilize the
ICTs in order to execute knowledge rich working tasks with
minimum efforts and with sufficient comfort level. The proposed
technology solution for PWD will support voice recognition along
with normal keyboard and mouse to control the smart help and smart
editor with dynamic auto display interface that satisfies the
requirements for different PWD group. In addition, a smart help will
provide intelligent intervention based on the behavior of PWD to
guide them and warn them about possible misbehavior. PWD can
communicate with others using Voice over IP controlled by voice
recognition. Moreover, Auto Emergency Help Response would be
supported to assist PWD in case of emergency. This proposed
technology solution intended to make PWD very effective at the
work environment and flexible using voice to conduct their tasks at
the work environment. The proposed solution aims to provide
favorable outcomes that assist PWD at the work place, with the
opportunity to participate in PWD assistive technology innovation
market which is still small and rapidly growing as well as upgrading
their quality of life to become similar to the normal people at the
workplace. Finally, the proposed smart help solution is applicable in
all workplace setting, including offices, manufacturing, hospital, etc.
Abstract: Children are more susceptible to medication errors
than adults. Medication administration process is the last stage in the
medication treatment process and most of the errors detected in this
stage. Little research has been undertaken about medication errors in
children in the Middle East countries. This study was aimed to
evaluate how the paediatric nurses adhere to the medication
administration policy and also to identify any medication preparation
and administration errors or any risk factors. An observational,
prospective study of medication administration process from when
the nurses preparing patient medication until administration stage
(May to August 2014) was conducted in Saudi Arabia. Twelve
paediatric nurses serving 90 paediatric patients were observed. 456
drug administered doses were evaluated. Adherence rate was variable
in 7 steps out of 16 steps. Patient allergy information, dose
calculation, drug expiry date were the steps in medication
administration with lowest adherence rates. 63 medication
preparation and administration errors were identified with error rate
13.8% of medication administrations. No potentially life-threating
errors were witnessed. Few logistic and administrative factors were
reported. The results showed that the medication administration
policy and procedure need an urgent revision to be more sensible for
nurses in practice. Nurses’ knowledge and skills regarding to the
medication administration process should be improved.
Abstract: Anultra-low power capacitor less low-dropout voltage
regulator with improved transient response using gain enhanced feed
forward path compensation is presented in this paper. It is based on a
cascade of a voltage amplifier and a transconductor stage in the feed
forward path with regular error amplifier to form a composite gainenhanced
feed forward stage. It broadens the gain bandwidth and thus
improves the transient response without substantial increase in power
consumption. The proposed LDO, designed for a maximum output
current of 100 mA in UMC 180 nm, requires a quiescent current of
69 )A. An undershot of 153.79mV for a load current changes from
0mA to 100mA and an overshoot of 196.24mV for current change of
100mA to 0mA. The settling time is approximately 1.1 )s for the
output voltage undershooting case. The load regulation is of 2.77
)V/mA at load current of 100mA. Reference voltage is generated by
using an accurate band gap reference circuit of 0.8V.The costly
features of SOC such as total chip area and power consumption is
drastically reduced by the use of only a total compensation
capacitance of 6pF while consuming power consumption of 0.096
mW.
Abstract: Although several factors that affect learning to
program have been identified over the years, there continues to be no
indication of any consensus in understanding why some students learn
to program easily and quickly while others have difficulty. Seldom
have researchers considered the problem of how to help the students
enhance the programming learning outcome. The research had been
conducted at a high school in Taiwan. Students participating in the
study consist of 330 tenth grade students enrolled in the Basic
Computer Concepts course with the same instructor. Two types of
training methods-instruction-oriented and exploration-oriented were
conducted. The result of this research shows that the
instruction-oriented training method has better learning performance
than exploration-oriented training method.
Abstract: Lawsone is a pigment that occurs naturally in plants.
It has been used as a skin and hair dye for a long time. Moreover, its
different biological activities have been reported. The present study
focused on the effect of lawsone on a plant cell model represented by
tobacco BY-2 cell suspension culture, which is used as a model
comparable with the HeLa cells. It has been shown that lawsone
inhibits the cell growth in the concentration-dependent manner. In
addition, changes in DNA methylation level have been determined.
We observed decreasing level of DNA methylation in the presence of
increasing concentrations of lawsone. These results were
accompanied with overproduction of reactive oxygen species (ROS).
Since epigenetic modifications can be caused by different stress
factors, there could be a connection between the changes in the level
of DNA methylation and ROS production caused by lawsone.