Abstract: Lateral Geniculate Nucleus (LGN) is the relay center
in the visual pathway as it receives most of the input information
from retinal ganglion cells (RGC) and sends to visual cortex. Low
threshold calcium currents (IT) at the membrane are the unique
indicator to characterize this firing functionality of the LGN neurons
gained by the RGC input. According to the LGN functional
requirements such as functional mapping of RGC to LGN, the
morphologies of the LGN neurons were developed. During the
neurological disorders like glaucoma, the mapping between RGC and
LGN is disconnected and hence stimulating LGN electrically using
deep brain electrodes can restore the functionalities of LGN. A
computational model was developed for simulating the LGN neurons
with three predominant morphologies each representing different
functional mapping of RGC to LGN. The firings of action potentials
at LGN neuron due to IT were characterized by varying the
stimulation parameters, morphological parameters and orientation. A
wide range of stimulation parameters (stimulus amplitude, duration
and frequency) represents the various strengths of the electrical
stimulation with different morphological parameters (soma size,
dendrites size and structure). The orientation (0-1800) of LGN
neuron with respect to the stimulating electrode represents the angle
at which the extracellular deep brain stimulation towards LGN
neuron is performed. A reduced dendrite structure was used in the
model using Bush–Sejnowski algorithm to decrease the
computational time while conserving its input resistance and total
surface area. The major finding is that an input potential of 0.4 V is
required to produce the action potential in the LGN neuron which is
placed at 100 μm distance from the electrode. From this study, it can
be concluded that the neuroprostheses under design would need to
consider the capability of inducing at least 0.4V to produce action
potentials in LGN.
Abstract: This paper describes the development of a DNA-based
nanobiosensor to detect the dengue virus in mosquito using
electrically active magnetic (EAM) nanoparticles as concentrator and
electrochemical transducer. The biosensor detection encompasses
two sets of oligonucleotide probes that are specific to the dengue
virus: the detector probe labeled with the EAM nanoparticles and the
biotinylated capture probe. The DNA targets are double hybridized to
the detector and the capture probes and concentrated from
nonspecific DNA fragments by applying a magnetic field.
Subsequently, the DNA sandwiched targets (EAM-detector probe–
DNA target–capture probe-biotin) are captured on streptavidin
modified screen printed carbon electrodes through the biotinylated
capture probes. Detection is achieved electrochemically by measuring
the oxidation–reduction signal of the EAM nanoparticles. Results
indicate that the biosensor is able to detect the redox signal of the
EAM nanoparticles at dengue DNA concentrations as low as 10
ng/μl.
Abstract: Concurrent planning of project scheduling and
material ordering can provide more flexibility to the project
scheduling problem, as the project execution costs can be enhanced.
Hence, the issue has been taken into account in this paper. To do so, a
mixed-integer mathematical model is developed which considers the
aforementioned flexibility, in addition to the materials quantity
discount and space availability restrictions. Moreover, the activities
duration has been treated as decision variables. Finally, the efficiency
of the proposed model is tested by different instances. Additionally,
the influence of the aforementioned parameters is investigated on the
model performance.
Abstract: Nature constantly changes as a result of human
necessities. This change mostly feels in natural water sources which
are reconstructed with an effect of dams and motorways. In other
respects, visual quality of the landscape gets a new and different
character during and after the construction of dams and motorways.
Changing and specialization new landscapes will be very important
to protection-usage balance to explore sustainable usage facilities.
The main cause of the selection of Artvin city is that it has very
important geographical location and one of the most attraction points
in the World with its biodiversity, conservation areas and natural
landscape characteristics. Many hydroelectric station and 7 dams are
situated, 3 of them have already been built on the Çoruh River in the
province of Artvin. As a result of dams, motorways route were reshaped
and the ways which have already changed because of
elevation is directly affected several of natural destruction. In
contrast, many different reservoirs in Coruh Basin provide new vista
point that has high visual quality. In this study, we would like to
evaluate with sustainable landscape design in 76 km river corridor,
which is mainly based on Deriner, Borçka and Muratlı Dams and
determination of their basin-lakes recreational potential and
opportunities. Lastly, we are going to give some suggestion about the
potential of the corridor.
Abstract: This paper concentrates on the sustainable traditional
architecture and urban planning in hot-humid regions of Iran. In a
vast country such as Iran with different climatic zones traditional
builders have presented series of logical solutions for human comfort.
The aim of this paper is to demonstrate traditional architecture in hothumid
climate of Iran as a sample of sustainable architecture. Iranian
traditional architecture has been able to response to environmental
problems for a long period of time. Its features are based on climatic
factors, local construction materials of hot-humid regions and culture.
This paper concludes that Iranian traditional architecture can be
addressed as a sustainable architecture.
Abstract: The current statuses of lifetime test of LaB6 hollow
cathode at the Lanzhou Institute of Physics (LIP), China, was
described. 5A LaB6 hollow cathode was design for LIPS-200 40mN
Xenon ion thruster, and it could be used for LHT-100 80 mN Hall
thruster, too. Life test of the discharge and neutralizer modes of LHC-5
hollow cathode were stared in October 2011, and cumulative operation
time reached 17,300 and 16,100 hours in April 2015, respectively. The
life of cathode was designed more than 11,000 hours. Parameters of
discharge and key structure dimensions were monitored in different
stage of life test indicated that cathodes were health enough. The test
will continue until the cathode cannot work or operation parameter is
not in normally. The result of the endurance test of cathode
demonstrated that the LaB6 hollow cathode is satisfied for the required
of thruster in life and performance.
Abstract: The objective of this work is to carryout critical
comparison of different actuation mechanisms like electrostatic,
thermal, piezoelectric, and magnetic with reference to a micro
cantilever. The relevant parameters like force generated,
displacement are compared in actuation methods. With these results,
helps in choosing the best actuation method for a particular
application. In this study, Comsol/Multiphysics software is used.
Modeling and simulation is done by considering the micro cantilever
of same dimensions as an actuator using all the above mentioned
actuation techniques. In addition to their small size, micro actuators
consume very little power and are capable of accurate results. In this
work, a comparison of actuation mechanisms is done to decide the
efficient system in micro domain.
Abstract: The paper discusses the problem of load transport
using farm tractors and road tractor units. This type of carriage of
goods is often done with farm vehicles. The tests were performed
with the PEMS equipment (Portable Emission Measurement System)
under actual traffic conditions. The vehicles carried a load of 20000
kg. This research method is one of the most desired because it
provides reliable information on the actual vehicle emissions and fuel
consumption (carbon balance method). For the tests, a route was
selected that simulated a trip from a small town to a food-processing
facility located in a city. The analysis of the obtained results gave a
clear answer as to what vehicles need to be used for carriage of this
type of cargo in terms of exhaust emissions and fuel consumption.
Abstract: Routing in adhoc networks is a challenge as nodes are
mobile, and links are constantly created and broken. Present ondemand
adhoc routing algorithms initiate route discovery after a path
breaks, incurring significant cost to detect disconnection and
establish a new route. Specifically, when a path is about to be broken,
the source is warned of the likelihood of a disconnection. The source
then initiates path discovery early, avoiding disconnection totally. A
path is considered about to break when link availability decreases.
This study modifies Adhoc On-demand Multipath Distance Vector
routing (AOMDV) so that route handoff occurs through link
availability estimation.
Abstract: Within Rapid Prototyping technologies are used many
types of materials. Many of them are recyclable but there are still as
plastic like, so practically they do not degrade in the landfill.
Polylactic acid (PLA) is one of the special plastic materials, which
are biodegradable and available for 3D printing within Fused
Deposition Modeling (FDM) technology. The question is, if the
mechanical properties of produced models are comparable to similar
technical plastic materials which are usual for prototype production.
Presented paper shows the experiments results for tensile strength
measurements for specimens prepared with different 3D printer
settings and model orientation. Paper contains also the comparison of
tensile strength values with values measured on specimens produced
by conventional technologies as injection moulding.
Abstract: Reduction of energy consumption in built
infrastructure, through the installation of energy-efficient
technologies, is a major approach to achieving sustainability. In
practice, the viability of energy efficiency projects strongly depends
on the cost reimbursement and profitability. These projects are
subject to failure if the actual cost savings do not reimburse the
project cost promptly. In such cases, refinancing could be a solution
to benefit from the long-term returns of the project, if implemented
wisely. However, very little is still known about the effect of
refinancing options on financial performance of energy efficiency
projects. In order to fill this gap, the present study investigates the
financial behavior of energy efficiency projects with focus on
refinancing options, such as Leveraged Loans. A System Dynamics
(SD) model is introduced, and the model application is presented
using an actual case-study data. The case study results indicate that
while high-interest start-ups make using Leveraged Loan inevitable,
refinancing can rescue the project and bring about profitability. This
paper also presents some managerial implications of refinancing
energy efficiency projects based on the case-study analysis. Results
of this study help to implement financially viable energy efficiency
projects so that the community could benefit from their
environmental advantages widely.
Abstract: Given the increase in the number of e-commerce sites,
the number of competitors has become very important. This means
that companies have to take appropriate decisions in order to meet the
expectations of their customers and satisfy their needs. In this paper,
we present a case study of applying LRFM (length, recency,
frequency and monetary) model and clustering techniques in the
sector of electronic commerce with a view to evaluating customers’
values of the Moroccan e-commerce websites and then developing
effective marketing strategies. To achieve these objectives, we adopt
LRFM model by applying a two-stage clustering method. In the first
stage, the self-organizing maps method is used to determine the best
number of clusters and the initial centroid. In the second stage, kmeans
method is applied to segment 730 customers into nine clusters
according to their L, R, F and M values. The results show that the
cluster 6 is the most important cluster because the average values of
L, R, F and M are higher than the overall average value. In addition,
this study has considered another variable that describes the mode of
payment used by customers to improve and strengthen clusters’
analysis. The clusters’ analysis demonstrates that the payment method is
one of the key indicators of a new index which allows to assess the
level of customers’ confidence in the company's Website.
Abstract: Numerical study of the static response of
homogeneous clay stratum considering a wide range of cohesion and
subject to foundation loads is presented. The linear elastic–perfectly
plastic constitutive relation with the von Mises yield criterion were
utilised to develop a numerically cost effective finite element model
for the soil while imposing a rigid body constrain to the foundation
footing. From the analyses carried out, estimate of the bearing
capacity factor, Nc as well as the ultimate load-carrying capacities of
these soils, effect of cohesion on foundation settlements, stress fields
and failure propagation were obtained. These are consistent with
other findings in the literature and hence can be a useful guide in
design of safe foundations in clay soils for buildings and other
structure.
Abstract: Cooperative groups through much research have been
recognized to churn remarkable achievements instead of solitary or
individualistic efforts. Based on Johnson and Johnson’s model of
cooperative learning, the five key components of cooperation are
positive interdependence, face-to-face promotive interaction,
individual accountability, social skills, and group processing. In
2011, the Malaysian Ministry of Higher Education (MOHE)
introduced the Holistic Student Development policy with the aim to
develop morally sound individuals equipped with lifelong learning
skills. The Community Service project was included in the
improvement initiative. The purpose of this study is to assess the
relationship of team-based learning in facilitating particularly
students’ positive interdependence and face-to-face promotive
interaction. The research methods involve in-depth interviews with
the team leaders and selected team members, and a content analysis
of the undergraduate students’ reflective journals. A significant
positive relationship was found between students’ progressive
outlook towards teamwork and the highlighted two components. The
key findings show that students have gained in their individual
learning and work results through teamwork and interaction with
other students. The inclusion of Community Service as a MOHE
subject resonates with cooperative learning methods that enhances
supportive relationships and develops students’ social skills together
with their professional skills.
Abstract: The analytical bright two soliton solution of the 3-
coupled nonlinear Schrödinger equations with variable coefficients in
birefringent optical fiber is obtained by Darboux transformation
method. To the design of ultra-speed optical devices, Soliton
interaction and control in birefringence fiber is investigated. Lax pair
is constructed for N coupled NLS system through AKNS method.
Using two-soliton solution, we demonstrate different interaction
behaviors of solitons in birefringent fiber depending on the choice of
control parameters. Our results shows that interactions of optical
solitons have some specific applications such as construction of logic
gates, optical computing, soliton switching, and soliton amplification
in wavelength division multiplexing (WDM) system.
Abstract: Broiler slaughter waste has become a major source of
pollution throughout the world. Utilization of broiler slaughter waste
by dry rendering process produced Rendered Chicken Oil (RCO), a
cheap raw material for biodiesel production and Carcass Meal a feed
ingredient for pets and fishes. Conversion of RCO into biodiesel may
open new vistas for generating wealth from waste besides controlling
the major havoc of environmental pollution. A two-step process to
convert RCO to good quality Biodiesel was invented. Acid catalysed
esterification of FFA followed by base catalysed transesterification of
triglycerides was carried out after meticulously standardizing the
methanol molar ratio, catalyst concentration, reaction temperature,
and reaction time to obtain the maximum biodiesel yield of 97.62%
and lowest glycerol yield of 6.96%. RCO biodiesel blend was tested
in a CRDI diesel engine. The results revealed that the blending of
commercial diesel with 20% RCO biodiesel (B20) lead to less engine
wear, a quieter engine and better fuel economy. The better lubricating
qualities of RCO B20 prevented over heating of engine, which
prolongs the engine life. RCO B20 can reduce the import of crude oil
and substantially reduce the engine emissions as proved by
significantly lower smoke levels, thus mitigating climatic changes.
Abstract: The purpose of this research is to investigate the
marketing mix that is perceived to be important for the small sized
hotels in Pattaya. This research provides insights through a review of
the marketing activities performed by the small sized hotels. Nine
owners & marketing manager of small sized hotels and resorts, all
local Chonburi people, were selected for an in-depth interview. The
research suggests that seven marketing mixes (e.g. Product, Price,
Place, Promotion, People, Physical Evidence and Process) were
commonly used by these hotels, however, three types – People, Price
and Physical Evidence were considered most important by the
owners.
Abstract: The main cause of Alzheimer disease (AD) was
believed to be mainly due to the accumulation of free radicals owing
to oxidative stress (OS) in brain tissue. The mechanism of the
neurotoxicity of Aluminum chloride (AlCl3) induced AD in
hippocampus Albino wister rat brain tissue, the curative & the
protective effects of Lipidium sativum group (LS) water extract were
assessed after 8 weeks by attenuated total reflection spectroscopy
ATR-IR and histologically by light microscope. ATR-IR results
revealed that the membrane phospholipid undergo free radical
attacks, mediated by AlCl3, primary affects the polyunsaturated fatty
acids indicated by the increased of the olefinic -C=CH sub-band area
around 3012 cm-1 from the curve fitting analysis. The narrowing in
the half band width (HBW) of the sνCH2 sub-band around 2852 cm-1
due to Al intoxication indicates the presence of trans form fatty acids
rather than gauch rotomer. The degradation of hydrocarbon chain to
shorter chain length, increasing in membrane fluidity, disorder, and
decreasing in lipid polarity in AlCl3 group indicated by the detected
changes in certain calculated area ratios compared to the control.
Administration of LS was greatly improved these parameters
compared to the AlCl3 group. Al influences the Aβ aggregation and
plaque formation, which in turn interferes to and disrupts the
membrane structure. The results also showed a marked increase in
the β-parallel and antiparallel structure, that characterize the Aβ
formation in Al-induced AD hippocampal brain tissue, indicated by
the detected increase in both amide I sub-bands around 1674, 1692
cm-1. This drastic increase in Aβ formation was greatly reduced in the
curative and protective groups compared to the AlCl3 group and
approached nearly the control values. These results supported too by
the light microscope. AlCl3 group showed significant marked
degenerative changes in hippocampal neurons. Most cells appeared
small, shrieked and deformed. Interestingly, the administration of LS
in curative and protective groups markedly decreases the amount of
degenerated cells compared to the non-treated group. In addition, the
intensity of congo red stained cells was decreased. Hippocampal
neurons looked more/or less similar to those of control. This study showed a promising therapeutic effect of Lipidium
sativum group (LS) on AD rat model that seriously overcome the
signs of oxidative stress on membrane lipid and restore the protein
misfolding.
Abstract: Lagos urban mini bus drivers play a critical role in the
transportation sector. The current major mode of transportation
within Lagos metropolis remains road transportation and this
confirms the relevance of urban mini-bus drivers in transporting the
populace to their various destinations. Other modes of transportation
such as the train and waterways are currently inadequate. Various
threats to the well-being of urban bus drivers include congested
traffic typical of modern day lifestyles, dwindling financial returns
due to long hours in traffic, fewer hours of sleep, inadequate diet,
time pressure, and assaults related to fare disputes. Several healthrelated
problems have been documented to be associated with urban
bus driving. For instance, greater rates of hypertension, obesity and
cholesterol level have been reported. Research studies are yet to
identify the influence of age and marital status on the well-being of
urban mini-bus drivers in Lagos metropolis. A study of this nature is
necessary as it is culturally perceived in Nigeria that older and
married people are especially influenced by family affiliation and
would behave in ways that would project positive outcomes. The
study sample consisted of 150 urban mini-bus drivers who were
conveniently sampled from six (6) different terminuses where their
journey begins and terminates. The well-being questionnaire was
administered to participants. The criteria for inclusion in the study
included the ability to read in English language and the confirmation
that interested participants were on duty and suited to be driving
mini-buses. Due to the nature of the job of bus driving, the researcher
administered the questionnaires on participants who were free and
willing to respond to the survey. All participants were males of
various age groups and of different marital statuses. Results of
analyses conducted revealed no significant influence of age and
marital status on the well-being of urban mini-bus drivers. This
indicates that the well-being of urban mini bus drivers is not
influenced by age or marital status. The findings of this study have
cultural implications. It negates the popularly held belief that older
and married people care more about their well-being than younger
and single people. It brings to fore the need to also identify and
consider other factors when certifying people for the job of urban bus
driving.
Abstract: Highly developed technology and highly competitive
global market highlight the important role of competitive advantages
and operation performances in sustainable company operation.
Activity-Based Costing (ABC) provides accurate operation cost and
operation performance information. Rich literatures provide relevant
research with cases study on Activity-Based Costing application, but
the research on cause relationship between key success factors and its
specific outcome, such as profitability or share market are few. These
relationships provide the ways to handle the key success factors to
achieve the specific outcomes for ensuring to promote the competitive
advantages and operation performances. The main purposes of this
research are exploring the key success paths by Key Success Paths
approach which will lead the ways to apply Activity-Base Costing.
The Key Success Paths is the innovative method which is exploring
the cause relationships and explaining what are the effects of key
success factors to specific outcomes of Activity-Based Costing
implementation. The cause relationships between key success factors
and successful specific outcomes are Key Success Paths (KSPs). KSPs
are the guidelines to lead the cost management strategies to achieve the
goals of competitive advantages and operation performances. The
research findings indicate that good management system design may
affect the well outcomes of Activity-Based Costing application and
achieve to outstanding competitive advantage, operating performance
and profitability as well by KSPs exploration.