Abstract: Various assisted reproductive techniques have been
developed and refined to obtain a large number of offspring from
genetically superior animals or obtain offspring from infertile (or
subfertile) animals. The embryo transfer is one assisted reproductive
technique developed well, aimed at increased productivity of selected
females, disease control, importation and exportation of livestock,
rapid screening of AI sires for genetically recessive characteristics,
treatment or circumvention of certain types of infertility. Embryo
transfer also is a useful research tool for evaluating fetal and maternal
interactions. This technique has been applied to nearly every species
of domestic animal and many species of wildlife and exotic animals,
including humans and non-human primates. The successful of
embryo transfers have been limited to within-animal, homologous
replacement of the embryos. There are several examples of
interspecific and intergeneric embryo transfers in which embryos
implanted but did not develop to term: sheep and goat, mouse and rat.
An immunological rejections and placental incompatibility between
the embryo and the surrogate mother appear to restrict interspecific
embryo transfer/interspecific pregnancy. Recently, preimplantation
embryo manipulation procedures have been applied, such as
technique of inner cell mass transfer. This technique will possible to
overcome the reproductive barrier interspecific embryo
transfer/interspecific pregnancy, if there is a protective mechanism
which prevents recognition of the foreign fetus by the mother of the
other species
Abstract: The avian phytohaemagglutinin skin test is being
proved as an in vivo system for the evaluation an avian in vivo T cell
mitogenicity. The test system was one week old Gallus domesticus
broiler Chickens. Five replicates were done for each of the whole,
1:10 dilutions of each of 0.05 IU tuberculin, tetanus immunoglobulin
and DPT vaccine as test materials. The evaluation parameters were
the skin indurations and lymphoblast percentages in bone marrow
lymphocytes.
Tuberculin indurations were 2.06 and 1.26mm for 0.05 IU
respectively while lymphoblast percent were 0.234 and 0.1
accordingly.
The skin indurations of 135mg/ml and 1.35mg/ml tetanus
immunoglobulin were 4.86 and 3.96mm while lymphoblast
percentages were 0.3 and 0.14 respectively.
The whole DPT and 1:10 concentration were with 4.5 and 3.2mm
while their lymphoblast percentages were 0.28 and 0.12 accordingly.
Thus the mitogenicity of the test materials was of dependant type.
Abstract: This study reveals that anti-immigrant policies in
Europe result from a process of securitization, and that, within this
process, radical right parties have been formulating discourses and
approaches through a construction process by using some common
security themes. These security themes can be classified as national
security, economic security, cultural security and internal security.
The frequency with which radical right parties use these themes may
vary according to the specific historical, social and cultural
characteristics of a particular country.
Abstract: In this work, we present for the first time in our perception an efficient digital watermarking scheme for mpeg audio layer 3 files that operates directly in the compressed data domain, while manipulating the time and subband/channel domain. In addition, it does not need the original signal to detect the watermark. Our scheme was implemented taking special care for the efficient usage of the two limited resources of computer systems: time and space. It offers to the industrial user the capability of watermark embedding and detection in time immediately comparable to the real music time of the original audio file that depends on the mpeg compression, while the end user/audience does not face any artifacts or delays hearing the watermarked audio file. Furthermore, it overcomes the disadvantage of algorithms operating in the PCMData domain to be vulnerable to compression/recompression attacks, as it places the watermark in the scale factors domain and not in the digitized sound audio data. The strength of our scheme, that allows it to be used with success in both authentication and copyright protection, relies on the fact that it gives to the users the enhanced capability their ownership of the audio file not to be accomplished simply by detecting the bit pattern that comprises the watermark itself, but by showing that the legal owner knows a hard to compute property of the watermark.
Abstract: One of the essential requirements of a realistic
surgical simulator is to reproduce haptic sensations due to the
interactions in the virtual environment. However, the interaction need
to be performed in real-time, since a delay between the user action
and the system reaction reduces the immersion sensation. In this
paper, a prototype of a coronary stent implant simulator is present;
this system allows real-time interactions with an artery by means of a
specific haptic device. To improve the realism of the simulation, the
building of the virtual environment is based on real patients- images
and a Web Portal is used to search in the geographically remote
medical centres a virtual environment with specific features in terms
of pathology or anatomy. The functional architecture of the system
defines several Medical Centres in which virtual environments built
from the real patients- images and related metadata with specific
features in terms of pathology or anatomy are stored. The searched
data are downloaded from the Medical Centre to the Training Centre
provided with a specific haptic device and with the software
necessary both to manage the interaction in the virtual environment.
After the integration of the virtual environment in the simulation
system it is possible to perform training on the specific surgical
procedure.
Abstract: Students in high education are presented with new terms and concepts in nearly every lecture they attend. Many of them prefer Web-based self-tests for evaluation of their concepts understanding since they can use those tests independently of tutors- working hours and thus avoid the necessity of being in a particular place at a particular time. There is a large number of multiple-choice tests in almost every subject designed to contribute to higher level learning or discover misconceptions. Every single test provides immediate feedback to a student about the outcome of that test. In some cases a supporting system displays an overall score in case a test is taken several times by a student. What we still find missing is how to secure delivering of personalized feedback to a user while taking into consideration the user-s progress. The present work is motivated to throw some light on that question.
Abstract: This paper aims at overviewing the topics of a research project (CARDIOSENSOR) on the field of health sciences (biomaterials and biomedical engineering). The project has focused on the development of a nanosensor for the assessment of the risk of cardiovascular diseases by the monitoring of C-reactive protein (CRP), which has been currently considered as the best validated inflammatory biomarker associated to cardiovascular diseases. The project involves tasks such as: 1) the development of sensor devices based on field effect transistors (FET): assembly, optimization and validation; 2) application of sensors to the detection of CRP in standard solutions and comparison with enzyme-linked immunosorbent assay (ELISA); and 3) application of sensors to real samples such as blood and saliva and evaluation of their ability to predict the risk of cardiovascular disease.
Abstract: The enthusiasm for gluten avoidance in a growing
market is met by improvements in sensitive detection methods for
analysing gluten content. Paradoxically, manufacturers employ no
such systems in the production process but continue to market their
product as gluten free, a significant risk posed to an undetermined
coeliac population. This paper resonates with an immunological
response that causes gastrointestinal scarring and villous atrophy with
the conventional description of personal injury. This thesis divulges
into evaluating potential inadequacies of gluten labelling laws which
not only present a diagnostic challenge for general practitioners in the
UK but it also exposes a less than adequate form of available legal
protection to those who suffer adverse reactions as a result of gluten
digestion. Central to this discussion is whether a claim brought in
misrepresentation, negligence and/or under the Consumer Protection
Act 1987 could be sustained. An interesting comparison is then made
with the legal regimes of neighboring jurisdictions furthering the
theme of a legally un-catered for gluten kingdom.
Abstract: Attempts were made to identify anuran glial cells. They were found as nervous tissue resident. Having stage dependent morphotype changes, whereby, appeared as an ovoid to oval in resting state and amoeboid mrophotypes in activated state, stained fairly with methylene blue and take up Pelikane blue 10% aqueous solution, as well as having the ability to phagocytize heat killed Staphylococcus aureus. They were delineated from the migrating peripheral monocytes by morphotypic and morphometeric differences. Such criteria were consistence with glial cells. Thus, the anuran glial cells are being identified in the frog Rana ridibunda Pallas 1771 and this animal can be of use as a simple model for the immunobiology of glial cells.
Abstract: Cardiovascular diseases, principally atherosclerosis, are responsible for 30% of world deaths. Atherosclerosis is due to the formation of plaque. The fatty plaque may be at risk of rupture, leading typically to stroke and heart attack. The plaque is usually associated with a high degree of lumen reduction, called a stenosis.It is increasingly recognized that the initiation and progression of disease and the occurrence of clinical events is a complex interplay between the local biomechanical environment and the local vascular biology. The aim of this study is to investigate the flow behavior through a stenosed artery. A physical experiment was performed using an artery model and blood analogue fluid. An axisymmetric model constructed consists of contraction and expansion region that follow a mathematical form of cosine function. A 30% diameter reduction was used in this study. The flow field was measured using particle image velocimetry (PIV). Spherical particles with 20μm diameter were seeded in a water-glycerol-NaCl mixture. Steady flow Reynolds numbers are 250. The area of interest is the region after the stenosis where the flow separation occurs. The velocity field was measured and the velocity gradient was investigated. There was high particle concentration in the recirculation zone. High velocity gradient formed immediately after the stenosis throat created a lift force that enhanced particle migration to the flow separation area.
Abstract: Since 2005, an SRF module of CESR type serves as the
accelerating cavity at the Taiwan Light Source in the National
Synchrotron Radiation Research Center. A 500-MHz niobium cavity
is immersed in liquid helium inside this SRF module. To reduce heat
load, the liquid helium vessel is thermally shielded by
liquid-nitrogen-cooled copper layer, and the beam chambers are also
anchored with pipes of the liquid nitrogen flow in middle of the liquid
helium vessel and the vacuum vessel. A strong correlation of the
movement of the cavity-s frequency tuner with the temperature
variation of parts cooled with liquid nitrogen was observed. A
previous study on a spare SRF module with the niobium cavity cooled
by liquid nitrogen instead of liquid helium, satisfactory suppression of
the thermal oscillation was achieved by attaching a temporary buffer
tank for the vented shielding nitrogen flow from the SRF module. In
this study, a home-made buffer tank is designed and integrated to the
spare SRF module with cavity cooled by liquid helium. Design,
construction, integration, and preliminary test results of this buffer
tank are presented.
Abstract: The aim of this study is to investigate the kinematics of undulatory elongated fish swimming against a velocity flow. We perform the experiments on European eel Anguilla Anguilla swimming in a hydrodynamic re-circulating tank with the velocity flow fixed at 0.2 m/s. We find that the undulating shape of overall eel body changes when it swims slantwise from the flow direction, by comparison to axial undulation shape. We examine this kinematics and we propose a general equation describing the lateral position of undulation body taking into account the direction of the eel-s swimming.
Abstract: Throughout the world, the Islamic way of banking and
financing is increasing. The same trend is also visible in Pakistan, where the Islamic banking sector is increasing in size and volume
each year. The question immediately arises as why the Pakistanis patronize the Islamic banking system? This study was carried out to
find whether following the Islamic rules in finance is the main factor for such selection or whether other factors such as customer service,
location, banking hour, physical facilities of the bank etc also have
importance. The study was carried by distributing questionnaire and
200 responses were collected from the clients of Islamic banks. The result showed that the service quality and other factors are as
important as following the Islamic rules for finance to retain old ustomers and catch new customers. The result is important and
Islamic banks can take actions accordingly to look after both the factors
Abstract: The effect of different tempering temperatures and heat treatment times on the corrosion resistance of austenitic stainless steels in oxalic acid was studied in this work using conventional weight loss and electrochemical measurements. Typical 304 and 316 stainless steel samples were tempered at 150oC, 250oC and 350oC after being austenized at 1050oC for 10 minutes. These samples were then immersed in 1.0M oxalic acid and their weight losses were measured at every five days for 30 days. The results show that corrosion of both types of ASS samples increased with an increase in tempering temperature and time and this was due to the precipitation of chromium carbides at the grain boundaries of these metals. Electrochemical results also confirm that the 304 ASS is more susceptible to corrosion than 316 ASS in this medium. This is attributed to the molybdenum in the composition of the latter. The metallographic images of these samples showed non–uniform distribution of precipitated chromium carbides at the grain boundaries of these metals and unevenly distributed carbides and retained austenite phases which cause galvanic effects in the medium.
Abstract: Micro droplet formation is considered as a growing
emerging area of research due to its wide-range application in
chemistry as well as biology. The mechanism of micro droplet
formation using two immiscible liquids running through a T-junction
has been widely studied.
We believe that the flow of these two immiscible phases can be of
greater important factor that could have an impact on out-flow
hydrodynamic behavior, the droplets generated and the size of the
droplets. In this study, the type of the capillary tubes used also
represents another important factor that can have an impact on the
generation of micro droplets.
The tygon capillary tubing with hydrophilic inner surface doesn't
allow regular out-flows due to the fact that the continuous phase
doesn't adhere to the wall of the capillary inner surface.
Teflon capillary tubing, presents better wettability than tygon
tubing, and allows to obtain steady and regular regimes of out-flow,
and the micro droplets are homogeneoussize.
The size of the droplets is directly dependent on the flows of the
continuous and dispersed phases. Thus, as increasing the flow of the
continuous phase, to flow of the dispersed phase stationary, the size
of the drops decreases. Inversely, while increasing the flow of the
dispersed phase, to flow of the continuous phase stationary, the size
of the droplet increases.
Abstract: We present a dextran modified silicon microring
resonator sensor for high density antibody immobilization. An array
of sensors consisting of three sensor rings and a reference ring was
fabricated and its surface sensitivity and the limit of detection were
obtained using polyelectrolyte multilayers. The mass sensitivity and
the limit of detection of the fabricated sensor ring are 0.35 nm/ng
mm-2 and 42.8 pg/mm2 in air, respectively. Dextran modified sensor
surface was successfully prepared by covalent grafting of oxidized
dextran on 3-aminopropyltriethoxysilane (APTES) modified silicon
sensor surface. The antibody immobilization on hydrogel dextran
matrix improves 40% compared to traditional antibody
immobilization method via APTES and glutaraldehyde linkage.
Abstract: During the last few decades in the academic field, the
debate has increased on the effects of social geography on the
opportunities of socioeconomic integration. On one hand, it has been
discussed how the contents of the urban structure and social
geography affect not only the way people interact, but also their
chances of social and economic integration. On the other hand, it has
also been discussed how the urban structure is also constrained and
transformed by the action of social actors. Without questioning the
powerful influence of structural factors, related to the logic of the
production system, labor markets, education and training, the
research has shown the role played by place of residence in shaping
individual outcomes such as unemployment. In the context of this
debate the importance of territory of residence with respect to the
problem of unemployment has been highlighted.
Although statistics of unemployment have already demonstrated
the unequal incidence of the phenomenon in social groups, the issue
of uneven territorial impact on the phenomenon at intra-urban level
remains relatively unknown.
The purpose of this article is to show and to interpret the spatial
patterns of unemployment in the city of Porto using GIS (Geographic
Information System - GIS) technology. Under this analysis the
overlap of the spatial patterns of unemployment with the spatial
distribution of social housing, allows the discussion of the
relationship that occurs between these patterns and the reasons that
might explain the relative immutability of socioeconomic problems in
some neighborhoods.
Abstract: The aims of this paper are to study the efficacy of
chitosan nanoparticles in stimulating specific antibody against
A/H1N1 influenza antigen in mice. Chitosan nanoparticles (CSN)
were characterized by TEM. The results showed that the average size
of CSN was from 80nm to 106nm. The efficacy of A/H1N1 influenza
vaccine loaded on the surface of CSN showed that loading efficiency
of A/H1N1 influenza antigen on CSN was from 93.75 to 100%. Safe
property of the vaccine were tested. In 10 days post vaccination,
group of CSN 30 kDa and 300 kDa loaded A/H1N1 influenza antigen
were the rate of immune response on mice to be 100% (9/9) higher
than Al(OH)3 and other adjuvant. 100% mice in the experiment of all
groups had immune response in 20 days post vaccination. The results
also showed that HI titer of the group using CSN 300 kDa as an
adjuvant increased significantly up to 3971 HIU, over three-fold
higher than the Al(OH)3 adjuvant, chitosan (CS), and one hundredfold
than the A/H1N1 antigen only. Stability of the vaccine
formulation was investigated.
Abstract: The use of the oncologic index ISTER allows for a more effective planning of the radiotherapic facilities in the hospitals. Any change in the radiotherapy treatment, due to unexpected stops, may be adapted by recalculating the doses to the new treatment duration while keeping the optimal prognosis. The results obtained in a simulation model on millions of patients allow the definition of optimal success probability algorithms.
Abstract: Investment in a constructed facility represents a cost in
the short term that returns benefits only over the long term use of the
facility. Thus, the costs occur earlier than the benefits, and the owners
of facilities must obtain the capital resources to finance the costs of
construction. A project cannot proceed without an adequate
financing, and the cost of providing an adequate financing can be
quite large. For these reasons, the attention to the project finance is an
important aspect of project management. Finance is also a concern to
the other organizations involved in a project such as the general
contractor and material suppliers. Unless an owner immediately and
completely covers the costs incurred by each participant, these
organizations face financing problems of their own. At a more
general level, the project finance is the only one aspect of the general
problem of corporate finance. If numerous projects are considered
and financed together, then the net cash flow requirements constitute
the corporate financing problem for capital investment. Whether
project finance is performed at the project or at the corporate level
does not alter the basic financing problem .In this paper, we will first
consider facility financing from the owner's perspective, with due
consideration for its interaction with other organizations involved in a
project. Later, we discuss the problems of construction financing
which are crucial to the profitability and solvency of construction
contractors. The objective of this paper is to present the steps utilized
to determine the best combination of minimum project financing.
The proposed model considers financing; schedule and maximum net
area .The proposed model is called Project Financing and Schedule
Integration using Genetic Algorithms "PFSIGA". This model
intended to determine more steps (maximum net area) for any project
with a subproject. An illustrative example will demonstrate the
feature of this technique. The model verification and testing are put
into consideration.