Abstract: In molecular biology, microarray technology is widely and successfully utilized to efficiently measure gene activity. If working with less studied organisms, methods to design custom-made microarray probes are available. One design criterion is to select probes with minimal melting temperature variances thus ensuring similar hybridization properties. If the microarray application focuses on the investigation of metabolic pathways, it is not necessary to cover the whole genome. It is more efficient to cover each metabolic pathway with a limited number of genes. Firstly, an approach is presented which minimizes the overall melting temperature variance of selected probes for all genes of interest. Secondly, the approach is extended to include the additional constraints of covering all pathways with a limited number of genes while minimizing the overall variance. The new optimization problem is solved by a bottom-up programming approach which reduces the complexity to make it computationally feasible. The new method is exemplary applied for the selection of microarray probes in order to cover all fungal secondary metabolite gene clusters for Aspergillus terreus.
Abstract: Hydrodesulfurization (HDS) of dibenzothiophene
(DBT) in a high pressure batch reactor was done at 320 °C on
CoMoS/Al2O3-B2O3 (4, 10, and 16 wt. % of Boria) using nhexadecane
as solvent, dimethyldisulfide (DMDS) in tetradecane as
sulfur agent, and stirring at 1000 rpm. The effects of boria were
investigated by using X-ray diffraction (XRD), Temperature
programmed desorption (TPD) of ammonia, and Brunauer-Emmet-
Teller (BET) experiments. The results showed that the catalyst
prepared with low boria content (4 wt. %) had HDS activity (in
pseudo first order kinetic constant basis) value ~1.45 times higher to
that of CoMoS/Al2O3 catalyst.
Abstract: The scientific achievements coming from molecular
biology depend greatly on the capability of computational
applications to analyze the laboratorial results. A comprehensive
analysis of an experiment requires typically the simultaneous study
of the obtained dataset with data that is available in several distinct
public databases. Nevertheless, developing a centralized access to
these distributed databases rises up a set of challenges such as: what
is the best integration strategy, how to solve nomenclature clashes,
how to solve database overlapping data and how to deal with huge
datasets. In this paper we present GeNS, a system that uses a simple and yet innovative approach to address several biological data integration issues. Compared with existing systems, the main
advantages of GeNS are related to its maintenance simplicity and to its coverage and scalability, in terms of number of supported
databases and data types. To support our claims we present the current use of GeNS in two concrete applications. GeNS currently contains more than 140 million of biological relations and it can be
publicly downloaded or remotely access through SOAP web services.
Abstract: A talking head system (THS) is presented to animate
the face of a speaking 3D avatar in such a way that it realistically
pronounces the given Korean text. The proposed system consists of
SAPI compliant text-to-speech (TTS) engine and MPEG-4 compliant
face animation generator. The input to the THS is a unicode text that is
to be spoken with synchronized lip shape. The TTS engine generates a
phoneme sequence with their duration and audio data. The TTS
applies the coarticulation rules to the phoneme sequence and sends a
mouth animation sequence to the face modeler. The proposed THS can
make more natural lip sync and facial expression by using the face
animation generator than those using the conventional visemes only.
The experimental results show that our system has great potential for
the implementation of talking head for Korean text.
Abstract: The research on two-wheeled inverted pendulum (TWIP) mobile robots or commonly known as balancing robots have gained momentum over the last decade in a number of robotic laboratories around the world. This paper describes the hardware design of such a robot. The objective of the design is to develop a TWIP mobile robot as well as MATLAB interfacing configuration to be used as flexible platform comprises of embedded unstable linear plant intended for research and teaching purposes. Issues such as selection of actuators and sensors, signal processing units, MATLAB Real Time Workshop coding, modeling and control scheme will be addressed and discussed. The system is then tested using a wellknown state feedback controller to verify its functionality.
Abstract: The paper discusses a 3D numerical solution of the inverse boundary problem for a continuous casting process of alloy. The main goal of the analysis presented within the paper was to estimate heat fluxes along the external surface of the ingot. The verified information on these fluxes was crucial for a good design of a mould, effective cooling system and generally the whole caster. In the study an enthalpy-porosity technique implemented in Fluent package was used for modeling the solidification process. In this method, the phase change interface was determined on the basis of the liquid fraction approach. In inverse procedure the sensitivity analysis was applied for retrieving boundary conditions. A comparison of the measured and retrieved values showed a high accuracy of the computations. Additionally, the influence of the accuracy of measurements on the estimated heat fluxes was also investigated.
Abstract: The kinetics of palm oil catalytic cracking over
aluminum containing mesoporous silica Al-MCM-41 (5% Al) was
investigated in a batch autoclave reactor at the temperatures range of
573 – 673 K. The catalyst was prepared by using sol-gel technique
and has been characterized by nitrogen adsorption and x-ray
diffraction methods. Surface area of 1276 m2/g with average pore
diameter of 2.54 nm and pore volume of 0.811 cm3/g was obtained.
The experimental catalytic cracking runs were conducted using 50 g
of oil and 1 g of catalyst. The reaction pressure was recorded at
different time intervals and the data were analyzed using Levenberg-
Marquardt (LM) algorithm using polymath software. The results
show that the reaction order was found to be -1.5 and activation
energy of 3200 J/gmol.
Abstract: The forest fires in Thailand are annual occurrence which is the cause of air pollutions. This study intended to estimate the emission from forest fire during 2005-2009 using MODerateresolution Imaging Spectro-radiometer (MODIS) sensor aboard the Terra and Aqua satellites, experimental data, and statistical data. The forest fire emission is estimated using equation established by Seiler and Crutzen in 1982. The spatial and temporal variation of forest fire emission is analyzed and displayed in the form of grid density map. From the satellite data analysis suggested between 2005 and 2009, the number of fire hotspots occurred 86,877 fire hotspots with a significant highest (more than 80% of fire hotspots) in the deciduous forest. The peak period of the forest fire is in January to May. The estimation on the emissions from forest fires during 2005 to 2009 indicated that the amount of CO, CO2, CH4, and N2O was about 3,133,845 tons, 47,610.337 tons, 204,905 tons, and 6,027 tons, respectively, or about 6,171,264 tons of CO2eq. They also emitted 256,132 tons of PM10. The year 2007 was found to be the year when the emissions were the largest. Annually, March is the period that has the maximum amount of forest fire emissions. The areas with high density of forest fire emission were the forests situated in the northern, the western, and the upper northeastern parts of the country.
Abstract: In recent years various types of electric vehicles
has gained again increasing attention as an environmentally
benign technology in transport. Especially for urban areas with
high local pollution this Zero-emission technology (at the point
of use) is considered to provide proper solutions. Yet, the bad
economics and the limited driving ranges are still major barriers
for a broader market penetration of battery electric vehicles
(BEV) and of fuel cell vehicles (FCV). The major result of our
analyses is that the most important precondition for a further
dissemination of BEV in urban areas are emission-free zones.
This is an instrument which allows the promotion of BEV
without providing excessive subsidies. In addition, it is
important to note that the full benefits of EV can only be
harvested if the electricity used is produced from renewable
energy sources. That is to say, it has to be ensured that the use of
BEV in urban areas is clearly linked to a green electricity
purchase model. And moreover, the introduction of a CO2-
emission-based tax system would support this requirement.
Abstract: The present study is aim to prepare and evaluate the selfnanoemulsifying drug delivery (SNEDDS) system of a poorly water soluble drug valsartan in order to achieve a better dissolution rate which would further help in enhancing oral bioavailability. The present research work describes a SNEDDS of valsartan using labrafil M 1944 CS, Tween 80 and Transcutol HP. The pseudoternary phase diagrams with presence and absence of drug were plotted to check for the emulsification range and also to evaluate the effect of valsartan on the emulsification behavior of the phases. The mixtures consisting of oil (labrafil M 1944 CS) with surfactant (tween 80), co-surfactant (Transcutol HP) were found to be optimum formulations. Prepared formulations were evaluated for its particle size distribution, nanoemulsifying properties, robustness to dilution, self emulsication time, turbidity measurement, drug content and invitro dissolution. The optimized formulations are further evaluated for heating cooling cycle, centrifugation studies, freeze thaw cycling, particle size distribution and zeta potential were carried out to confirm the stability of the formed SNEDDS formulations. The prepared formulation revealed t a significant improvement in terms of the drug solubility as compared with marketed tablet and pure drug.
Abstract: In this paper, the data correction algorithm is suggested
when the environmental air temperature varies. To correct the infrared
data in this paper, the initial temperature or the initial infrared image
data is used so that a target source system may not be necessary. The
temperature data obtained from infrared detector show nonlinear
property depending on the surface temperature. In order to handle this
nonlinear property, Taylor series approach is adopted. It is shown that
the proposed algorithm can reduce the influence of environmental
temperature on the components in the board. The main advantage of
this algorithm is to use only the initial temperature of the components
on the board rather than using other reference device such as black
body sources in order to get reference temperatures.
Abstract: This paper shows the results of empirical research. It
presents experiences of Polish companies from the Podkarpackie
voivodeship connected with implementing EMS according to the
requirements of the ISO 14001 international standard. The incentives
to introduce and certify organizational eco-innovation, which formal
EMSs are treated as, are presented in this paper.
Abstract: The phase diagrams and compositions of coexisting
phases have been determined for aqueous two-phase systems
containing poly(propylene glycol) with average molecular weight of
425 and sodium citrate at various pH of 3.93, 4.44, 4.6, 4.97, 5.1,
8.22. The effect of pH on the salting-out effect of poly (propylene
glycol) by sodium citrate has been studied. It was found that, an
increasing in pH caused the expansion of two-phase region.
Increasing pH also increases the concentration of PPG in the PPGrich
phase, while the salt-rich phase will be somewhat mole diluted.
Abstract: This paper uses quasi-steady molecular statics model
and diamond tool to carry out simulation temperature rise of nanoscale
orthogonal cutting single-crystal silicon. It further qualitatively
analyzes temperature field of silicon workpiece without considering
heat transfer and considering heat transfer. This paper supposes that
the temperature rise of workpiece is mainly caused by two heat sources:
plastic deformation heat and friction heat. Then, this paper develops a
theoretical model about production of the plastic deformation heat and
friction heat during nanoscale orthogonal cutting. After the increased
temperature produced by these two heat sources are added up, the
acquired total temperature rise at each atom of the workpiece is
substituted in heat transfer finite difference equation to carry out heat
transfer and calculates the temperature field in each step and makes
related analysis.
Abstract: In this paper, we present a new method for
incorporating global shift invariance in support vector machines.
Unlike other approaches which incorporate a feature extraction stage,
we first scale the image and then classify it by using the modified
support vector machines classifier. Shift invariance is achieved by
replacing dot products between patterns used by the SVM classifier
with the maximum cross-correlation value between them. Unlike the
normal approach, in which the patterns are treated as vectors, in our
approach the patterns are treated as matrices (or images). Crosscorrelation
is computed by using computationally efficient
techniques such as the fast Fourier transform. The method has been
tested on the ORL face database. The tests indicate that this method
can improve the recognition rate of an SVM classifier.
Abstract: Model-checking tools such as Symbolic Model Verifier
(SMV) and NuSMV are available for checking hardware designs.
These tools can automatically check the formal legitimacy of a
design. However, NuSMV is too low level for describing a complete
hardware design. It is therefore necessary to translate the system
definition, as designed in a language such as Verilog or VHDL, into
a language such as NuSMV for validation. In this paper, we present
a meta hardware description language, Melasy, that contains a code
generator for existing hardware description languages (HDLs) and
languages for model checking that solve this problem.
Abstract: Network-Centric Air Defense Missile Systems
(NCADMS) represents the superior development of the air defense
missile systems and has been regarded as one of the major research
issues in military domain at present. Due to lack of knowledge and
experience on NCADMS, modeling and simulation becomes an effective
approach to perform operational analysis, compared with
those equation based ones. However, the complex dynamic interactions
among entities and flexible architectures of NCADMS put forward
new requirements and challenges to the simulation framework
and models. ABS (Agent-Based Simulations) explicitly addresses
modeling behaviors of heterogeneous individuals. Agents have capability
to sense and understand things, make decisions, and act on the
environment. They can also cooperate with others dynamically to
perform the tasks assigned to them. ABS proves an effective approach
to explore the new operational characteristics emerging in
NCADMS. In this paper, based on the analysis of network-centric
architecture and new cooperative engagement strategies for
NCADMS, an agent-based simulation framework by expanding the
simulation framework in the so-called System Effectiveness Analysis
Simulation (SEAS) was designed. The simulation framework specifies
components, relationships and interactions between them, the
structure and behavior rules of an agent in NCADMS. Based on scenario
simulations, information and decision superiority and operational
advantages in NCADMS were analyzed; meanwhile some
suggestions were provided for its future development.
Abstract: To realize the vision of ubiquitous computing, it is
important to develop a context-aware infrastructure which can help
ubiquitous agents, services, and devices become aware of their
contexts because such computational entities need to adapt themselves
to changing situations. A context-aware infrastructure manages the
context model representing contextual information and provides
appropriate information. In this paper, we introduce Context-Aware
Middleware for URC System (hereafter CAMUS) as a context-aware
infrastructure for a network-based intelligent robot system and discuss
the ontology-based context modeling and reasoning approach which is
used in that infrastructure.
Abstract: This paper introduces application of multi degree of freedom fuzzy(MDOFF) controller in permanent magnet (PM)drive system. The drive system model is developed for FO control. Simulation of the system is carried out to predict the performance at NL and under load,. The results indicate that application of MDOFF controller is effective for sensorless PM drive system.
Abstract: Fuzzy logic system (FLS) is used in this study to
predict the tractive performance in terms of traction force, and
motion resistance for an intelligent air cushion track vehicle while it
operates in the swamp peat. The system is effective to control the
intelligent air –cushion system with measuring the vehicle traction
force (TF), motion resistance (MR), cushion clearance height (CH)
and cushion pressure (CP). Ultrasonic displacement sensor, pull-in
solenoid electromagnetic switch, pressure control sensor, micro
controller, and battery pH sensor are incorporated with the Fuzzy
logic system to investigate experimentally the TF, MR, CH, and CP.
In this study, a comparison for tractive performance of an intelligent
air cushion track vehicle has been performed with the results obtained
from the predicted values of FLS and experimental actual values. The
mean relative error of actual and predicted values from the FLS
model on traction force, and total motion resistance are found as 5.58
%, and 6.78 % respectively. For all parameters, the relative error of
predicted values are found to be less than the acceptable limits. The
goodness of fit of the prediction values from the FLS model on TF,
and MR are found as 0.90, and 0.98 respectively.