Abstract: In this research (using induction furnace process)
nodular iron with three different percentages of copper (residual,
0.5% and 1,2%) was obtained. Chemical analysis was performed by
mass spectrometry and microstructures were characterized by Optical
Microscopy (ASTM E3) and Scanning Electron Microscopy (SEM).
The study of mechanical behavior was carried out in a mechanical
test machine (ASTM E8) and a Pin on disk tribometer (ASTM G99)
was used to assess wear resistance. It is observed that the dissolution
of copper in crystal lattice increases the pearlite structure improving
the wear and hardness behavior, but producing a contrary effect on
the energy absorption.
Abstract: Doxorubicin, also known as Adriamycin, is an
anthracycline class of drug used in cancer chemotherapy. It is used in
the treatment of non-Hodgkin’s lymphoma, multiple myeloma, acute
leukemia, breast cancer, lung cancer, endometrium cancer and ovary
cancers. It functions via intercalating DNA and ultimately killing
cancer cells. The major side effects of doxorubicin are hair loss,
myelosuppression, nausea & vomiting, oesophagitis, diarrhea, heart
damage and liver dysfunction. The minor modifications in the
structure of compound exhibit large variation in the biological
activity, has prompted us to carry out the synthesis of sulfonamide
derivatives. Sulfonamide is an important feature with broad spectrum
of biological activity such as antiviral, antifungal, diuretics, antiinflammatory,
antibacterial and anticancer activities. Structure of the
synthesized compound N-(1-methyl-2-oxo-2-N-methyl anilinoethyl)
benzene sulfonamide confirmed by proton nuclear magnetic
resonance (1H NMR),13C NMR, Mass and FTIR spectroscopic tools
to assure the position of all protons and hence stereochemistry of the
molecule. Further we have reported the binding potential of
synthesized sulfonamide analogues in comparison to doxorubicin
drug using Auto Dock 4.2 software. Computational binding energy
(B.E.) and inhibitory constant (Ki) has been evaluated for the
synthesized compound in comparison of doxorubicin against Poly
(dA-dT).Poly (dA-dT) and Poly (dG-dC).Poly (dG-dC) sequences.
The in vitro cytotoxic study against human breast cancer cell lines
confirms the better anticancer activity of the synthesized compound
over currently in use anticancer drug doxorubicin. The IC50 value of
the synthesized compound is 7.12 μM whereas for doxorubicin is 7.2
μM.
Abstract: A quartz crystal microbalance (QCM) nanosensor was developed to detect lysozyme enzyme by functionalizing its gold surface with the attachment of poly(methacroyl-L-phenylalanine) (PMAPA) nanoparticles. PMAPA was chosen as a hydrophobic matrix. The hydrophobic nanoparticles were synthesized by micro-emulsion polymerization method. Hydrophobic QCM nanosensor was tested for real time detection of lysozyme enzyme from aqueous solution. The kinetic and affinity studies were determined by using lysozyme solutions with different concentrations. The responses related with mass (Δm) and frequency (Δf) shifts were used to evaluate adsorption properties.
Abstract: The purpose of this presentation is to describe an interdisciplinary teaching program that integrates physical education concepts using a philosophical approach. The presentation includes a review of: a) the philosophy of American education, b) the philosophy of sports and physical education, c) the interdisciplinary physical education program, d) professional development programs, (e) the Success of this physical education program, f) future of physical education. This unique interdisciplinary program has been implemented in an urban school physical education discipline in East Orange, New Jersey for over 10 years.
During the program the students realize that the bodies go through different experiences. The body becomes a place where a child can recognize in an enjoyable way to express and perceive particular feelings or mental states. Children may distinguish themselves to have high abilities in the social or other domains but low abilities in the field of athletics.
The goal of this program for the individuals is to discover new skills, develop and demonstrate age appropriate mastery level at different tasks, therefore the program consists of 9 to 12 sports, including many game. Each successful experience increases the awareness ability. Engaging in sports and physical activities are social movements involving groups of children in situations such as teams, friends, and recreational settings, which serve as a primary socializing agent for teaching interpersonal skills. As a result of this presentation the audience will reflect and explore how to structure a physical education program to integrate interdisciplinary subjects with philosophical concepts.
Abstract: Cement concrete is a complex mixture of different
materials. Behaviour of concrete depends on its mix proportions and
constituents when it is subjected to elevated temperatures. Principal
effects due to elevated temperatures are loss in compressive strength,
loss in weight or mass, change in colour and spall of concrete. The
experimental results of normal concrete and high strength concrete
subjected elevated temperatures at 200°C, 400°C, 600°C, and 800°C
and different cooling regimes viz. air cooling, water quenching on
different grade of concrete are reported in this paper.
Abstract: Organic Rankine Cycle (ORC) is the most commonly used method for recovering energy from small sources of heat. The investigation of the ORC in supercritical condition is a new research area as it has a potential to generate high power and thermal efficiency in a waste heat recovery system. This paper presents a steady state ORC model in supercritical condition and its simulations with a real engine’s exhaust data. The key component of ORC, evaporator, is modelled using finite volume method, modelling of all other components of the waste heat recovery system such as pump, expander and condenser are also presented. The aim of this paper is to investigate the effects of mass flow rate and evaporator outlet temperature on the efficiency of the waste heat recovery process. Additionally, the necessity of maintaining an optimum evaporator outlet temperature is also investigated. Simulation results show that modification of mass flow rate is the key to changing the operating temperature at the evaporator outlet.
Abstract: Sound exposure effects have been investigated by
broadcasting a group of broilers with sound of Quran verses (Group
B) whereas the other group is the control broilers (Group C). The
growth rate comparisons in terms of weight and raw meat texture
measured by shear force have been investigated. Twenty-seven
broilers were randomly selected from each group on Day 24 and
weight measurement was carried out every week till the harvest day
(Day 39).Group B showed a higher mean weight on Day 24 (1.441 ±
0.013 kg) than Group C. Significant difference in the weight on Day
39 existed for Group B compared to Group C (p < 0.05). However,
there was no significant (p >0.05) difference of shear force in the
same muscles (breast and drumstick raw meat) of both groups but the
shear force of the breast meat for Group B and C broilers was lower
(p < 0.05) than that of their drumstick meat. Thus, broadcasting the
sound of Quran verses in the coop can be applied to improve the
growth rate of broilers for producing better quality poultry.
Abstract: This paper presents a methodology using
Gravitational Search Algorithm for optimal placement of Phasor
Measurement Units (PMUs) in order to achieve complete
observability of the power system. The objective of proposed
algorithm is to minimize the total number of PMUs at the power
system buses, which in turn minimize installation cost of the PMUs.
In this algorithm, the searcher agents are collection of masses which
interact with each other using Newton’s laws of gravity and motion.
This new Gravitational Search Algorithm based method has been
applied to the IEEE 14-bus, IEEE 30-bus and IEEE 118-bus test
systems. Case studies reveal optimal number of PMUs with better
observability by proposed method.
Abstract: The research studies the behaviors based on
sufficiency economy philosophy at individual and community
levelsas well as the satisfaction of the urban community leaders by
collecting data with purposive sampling technique. For in-depth
interviews with 26 urban community leaders, the result shows that
the urban community leaders have good knowledge and
understanding about sufficiency economy philosophy. Especially in
terms of money spending, they must consider the need for living and
be economical. The activities in the community or society should not
take advantage of the others as well as colleagues. At present, most of
the urban community leaders live in sufficient way. They often spend
time with public service, but many families are dealing with debt.
Many communities have some political conflict and high family
allowances because of living in the urban communities with rapid
social and economic changes. However, there are many communities
that leaders have applied their wisdom in development for their
people by gathering and grouping the professionals to form activities
such as making chilli sauce, textile organization, making artificial
flowers to worship the sanctity. The most prominent group is the foot
massage business in Wat Pracha Rabue Tham. This professional
group is supported continuously by the government. One of the
factors in terms of satisfaction used for evaluating community leaders
is the customary administration in brotherly, interdependent way
rather than using the absolute power or controlling power, but using
the roles of leader to perform the activities with their people intently,
determinedly and having public mind for people.
Abstract: Non-linear FEM calculations are indispensable when
important technical information like operating performance of a
rubber component is desired. For example rubber bumpers built into
air-spring structures may undergo large deformations under load,
which in itself shows non-linear behavior. The changing contact
range between the parts and the incompressibility of the rubber
increases this non-linear behavior further. The material
characterization of an elastomeric component is also a demanding
engineering task.
The shape optimization problem of rubber parts led to the study of
FEM based calculation processes. This type of problems was posed
and investigated by several authors. In this paper the time demand of
certain calculation methods are studied and the possibilities of time
reduction is presented.
Abstract: In this study, we have focused our attention on
combining of molecular imprinting into nanofilms and QCM
nanosensor approaches and producing QCM nanosensor for anti-
CCP, chosen as model protein, using anti-CCP imprinted nanofilms.
The nonimprinted nanosensor was also prepared to evaluate the
selectivity of the imprinted nanosensor. Anti-CCP imprinted QCM
nanosensor was tested for real time detection of anti-CCP from
aqueous solution. The kinetic and affinity studies were determined by
using anti-CCP solutions with different concentrations. The
responses related with mass shifts (%m) and frequency shifts (%f)
were used to evaluate adsorption properties. To show the selectivity
of the anti-CCP imprinted QCM nanosensor, competitive adsorption
of anti-CCP and IgM was investigated. The results indicate that anti-
CCP imprinted QCM nanosensor has higher adsorption capabilities
for anti-CCP than for IgM, due to selective cavities in the polymer
structure.
Abstract: The objective of this study was to identify the optimal
level of partial replacement of Portland cement by the ashes
originating from burning straw and bagasse from sugar cane (ASB).
Order to this end, were made five series of flat plates and cylindrical
bodies: control and others with the partial replacement in 20, 30, 40
and 50% of ASB in relation to the mass of the Ordinary Portland
cement, and conducted a mechanical testing of simple axial
compression (cylindrical bodies) and the four-point bending (flat
plates) and determined water absorption (WA), bulk density (BD)
and apparent void volume (AVV) on both types of specimens. Based
on the data obtained, it may be noted that the control treatment
containing only Portland cement, obtained the best results. However,
the cylindrical bodies with 20% ashes showed better results
compared to the other treatments. And in the formulations plates, the
treatment which showed the best results was 30% cement
replacement by ashes.
Abstract: Biofuels production has come forth as a future
technology to combat the problem of depleting fossil fuels. Bio-based
ethanol production from enzymatic lignocellulosic biomass
degradation serves an efficient method and catching the eye of
scientific community. High cost of the enzyme is the major obstacle
in preventing the commercialization of this process. Thus main
objective of the present study was to optimize composition of
medium components for enhancing cellulase production by newly
isolated strain of Bacillus tequilensis. Nineteen factors were taken
into account using statistical Plackett-Burman Design. The significant
variables influencing the cellulose production were further employed
in statistical Response Surface Methodology using Central
Composite Design for maximizing cellulase production. The
optimum medium composition for cellulase production was: peptone
(4.94 g/L), ammonium chloride (4.99 g/L), yeast extract (2.00 g/L),
Tween-20 (0.53 g/L), calcium chloride (0.20 g/L) and cobalt chloride
(0.60 g/L) with pH 7, agitation speed 150 rpm and 72 h incubation at
37oC. Analysis of variance (ANOVA) revealed high coefficient of
determination (R2) of 0.99. Maximum cellulase productivity of 11.5
IU/ml was observed against the model predicted value of 13 IU/ml.
This was found to be optimally active at 60oC and pH 5.5.
Abstract: The restrained construction zoning, an important part
in the urban master plan, is a necessary planning tool to control the city
sprawl, to guarantee the reservation implementation of the various
types of protective elements, and to realize the storage of the essential
urban spatial resources. Simultaneously, owing to the diverse
constitutes of restrained construction area and the various stakeholders
involved in, its planning requires an overall consideration of all
elements from the perspective of coordination+, balance and
practicability to deal with the problems and conflicts in this process.
Taking Yangzijin Ecological Restrained Construction Area in
Yangzhou as an example, this study analyzes all the potential actors,
agencies and stakeholders in this restrained construction area, as well
as the relevant conflicts between each other. Besides, this study tries to
build up a planning procedure based on the framework of governance
theory, and proposes a possible planning method that combines
"rigidity" and "flexibility" to protect the ecological limitation
boundary, to take every interest into account, and to promote economic
development in a harmonious society.
Abstract: As the use of geothermal energy grows internationally
more effort is required to monitor and protect areas with rare and
important geothermal surface features. A number of approaches are
presented for developing and calibrating numerical geothermal
reservoir models that are capable of accurately representing
geothermal surface features. The approaches are discussed in the
context of cases studies of the Rotorua geothermal system and the
Orakei-korako geothermal system, both of which contain important
surface features. The results show that models are able to match the
available field data accurately and hence can be used as valuable
tools for predicting the future response of the systems to changes in
use.
Abstract: An investigation into Cahn-Hilliard equation was
carried out through numerical simulation to identify a possible phase
separation for one and two dimensional domains. It was observed that
this equation can reproduce important mass fluxes necessary for
phase separation within the miscibility gap and for coalescence of
particles.
Abstract: This study carried out comparative seismic
performance of reinforced concrete frames infilled by masonry walls
with different heights. Partial and fully infilled reinforced concrete
frames were modeled for the research objectives and the analysis
model for a bare reinforced concrete frame was also established for
comparison. Non–linear static analyses for the studied frames were
performed to investigate their structural behavior under extreme
seismic loads and to find out their collapse mechanism. It was
observed from analysis results that the strengths of the partial infilled
reinforced concrete frames are increased and their ductilities are
reduced, as infilled masonry walls are higher. Especially, reinforced
concrete frames with higher partial infilled masonry walls would
experience shear failures. Non–linear dynamic analyses using 10
earthquake records show that the bare and fully infilled reinforced
concrete frame present stable collapse mechanism while the reinforced
concrete frames with partially infilled masonry walls collapse in more
brittle manner due to short-column effects.
Abstract: Background: The effectiveness of mirror therapy
(MT) has been investigated in acute hemiplegia. The present study
examines whether MT, given during chronic stroke, was more
effective in promoting motor recovery of the lower extremity and
walking speed than standard rehabilitation alone. Methods: The study
enrolled 30 patients with chronic stroke. Fifteen patients each were
assigned to the treatment group and the control group. All patients
received a conventional rehabilitation program for a 4-week period.
In addition to this rehabilitation program, patients in the treatment
group received mirror therapy for 4 weeks, 5 days a week. Main
measures: Passive ankle joint dorsiflexion range of motion, gait
speed, Brunnstrom stages of motor recovery, plantar flexor muscle
tone by Modified Ashworth Scale. Results: No significant difference
was found in the outcome measures among groups before treatment.
When compared with standard rehabilitation, mirror therapy
improved Ankle ROM, Brunnstrom stages and waking speed
(p < 0.05). However, there were no significant differences between
two groups on MAS (P > 0.05).Conclusion: Mirror therapy combined
with a conventional stroke rehabilitation program enhances lowerextremity
motor recovery and walking speed in chronic stroke
patients.
Abstract: Modern low earth orbit (LEO) satellites that require multi-mission flexibility are highly likely to be repositioned between different operational orbits. While executing this process the satellite may experience high levels of vibration and environmental hazards, exposing the deployed solar panel to dangerous stress levels, fatigue and space debris, hence it is desirable to retract the solar array before satellite repositioning to avoid damage or failure.
A novel concept of deployable/retractable hybrid solar array systemcomposed of both rigid and flexible solar panels arranged within a petal formation, aimed to provide a greater power to volume ratio while dramatically reducing mass and cost is proposed.
Abstract: In this paper, the improvement by deconvolution of
the depth resolution in Secondary Ion Mass Spectrometry (SIMS)
analysis is considered. Indeed, we have developed a new Tikhonov-
Miller deconvolution algorithm where a priori model of the solution
is included. This is a denoisy and pre-deconvoluted signal obtained
from: firstly, by the application of wavelet shrinkage algorithm,
secondly by the introduction of the obtained denoisy signal in an
iterative deconvolution algorithm. In particular, we have focused the
light on the effect of the iterations number on the evolution of the
deconvoluted signals. The SIMS profiles are multilayers of Boron in
Silicon matrix.