Abstract: Female breast cancer is the second in frequency after cervical cancer. Surgery is the most common treatment for breast cancer, followed by chemotherapy as a treatment of choice. Although effective, it causes serious side effects. Controlled-release drug delivery is an alternative method to improve the efficacy and safety of the treatment. It can release the dosage of drug between the minimum effect concentration (MEC) and minimum toxic concentration (MTC) within tumor tissue and reduce the damage of normal tissue and the side effect. Because an in vivo experiment of this system can be time-consuming and labor-intensive, a mathematical model is desired to study the effects of important parameters before the experiments are performed. Here, we describe a 3D mathematical model to predict the release of doxorubicin from pluronic gel to treat human breast cancer. This model can, ultimately, be used to effectively design the in vivo experiments.
Abstract: We review a knowledge extractor model in
constructing 3G Killer Applications. The success of 3G is essential
for Government as it became part of Telecommunications National
Strategy. The 3G wireless technologies may reach larger area and
increase country-s ICT penetration. In order to understand future
customers needs, the operators require proper information
(knowledge) lying inside. Our work approached future customers as
complex system where the complex knowledge may expose regular
behavior. The hidden information from 3G future customers is
revealed by using fractal-based questionnaires. Afterward, further
statistical analysis is used to match the results with operator-s
strategic plan. The developments of 3G applications also consider its
saturation time and further improvement of the application.
Abstract: Uncertainties of a serial production line affect on the
production throughput. The uncertainties cannot be prevented in a
real production line. However the uncertain conditions can be
controlled by a robust prediction model. Thus, a hybrid model
including autoregressive integrated moving average (ARIMA) and
multiple polynomial regression, is proposed to model the nonlinear
relationship of production uncertainties with throughput. The
uncertainties under consideration of this study are demand, breaktime,
scrap, and lead-time. The nonlinear relationship of production
uncertainties with throughput are examined in the form of quadratic
and cubic regression models, where the adjusted R-squared for
quadratic and cubic regressions was 98.3% and 98.2%. We optimized
the multiple quadratic regression (MQR) by considering the time
series trend of the uncertainties using ARIMA model. Finally the
hybrid model of ARIMA and MQR is formulated by better adjusted
R-squared, which is 98.9%.
Abstract: This paper deals with new concept of using compressed atmospheric air as a zero pollution power source for running motorbikes. The motorbike is equipped with an air turbine in place of an internal combustion engine, and transforms the energy of the compressed air into shaft work. The mathematical modeling and performance evaluation of a small capacity compressed air driven vaned type novel air turbine is presented in this paper. The effect of isobaric admission and adiabatic expansion of high pressure air for different rotor to casing diameter ratios with respect to different vane angles (number of vanes) have been considered and analyzed. It is found that the shaft work output is optimum for some typical values of rotor / casing diameter ratios at a particular value of vane angle (no. of vanes). In this study, the maximum power is obtained as 4.5kW - 5.3kW (5.5-6.25 HP) when casing diameter is taken 100 mm, and rotor to casing diameter ratios are kept from 0.65 to 0.55. This value of output is sufficient to run motorbike.
Abstract: As more people from non-technical backgrounds
are becoming directly involved with large-scale ontology
development, the focal point of ontology research has shifted
from the more theoretical ontology issues to problems
associated with the actual use of ontologies in real-world,
large-scale collaborative applications. Recently the National
Science Foundation funded a large collaborative ontology
development project for which a new formal ontology model,
the Ontology Abstract Machine (OAM), was developed to
satisfy some unique functional and data representation
requirements. This paper introduces the OAM model and the
related algorithms that enable maintenance of an ontology that
supports node-based user access. The successful software
implementation of the OAM model and its subsequent
acceptance by a large research community proves its validity
and its real-world application value.
Abstract: In this study, aeroelastic response and performance
analyses have been conducted for a 5MW-Class composite wind
turbine blade model. Advanced coupled numerical method based on
computational fluid dynamics (CFD) and computational flexible
multi-body dynamics (CFMBD) has been developed in order to
investigate aeroelastic responses and performance characteristics of
the rotating composite blade. Reynolds-Averaged Navier-Stokes
(RANS) equations with k-ω SST turbulence model were solved for
unsteady flow problems on the rotating turbine blade model. Also,
structural analyses considering rotating effect have been conducted
using the general nonlinear finite element method. A fully implicit
time marching scheme based on the Newmark direct integration
method is applied to solve the coupled aeroelastic governing equations
of the 3D turbine blade for fluid-structure interaction (FSI) problems.
Detailed dynamic responses and instantaneous velocity contour on the
blade surfaces which considering flow-separation effects were
presented to show the multi-physical phenomenon of the huge rotating
wind- turbine blade model.
Abstract: Maize and Indian mustard are significant crops in
semi-arid climate zones of India. Improved water management
requires precise scheduling of irrigation, which in turn requires an
accurate computation of daily crop evapotranspiration (ETc). Daily
crop evapotranspiration comes as a product of reference
evapotranspiration (ET0) and the growth stage specific crop
coefficients modified for daily variation. The first objective of
present study is to develop crop coefficients Kc for Maize and Indian
mustard. The estimated values of Kc for maize at the four crop
growth stages (initial, development, mid-season, and late season) are
0.55, 1.08, 1.25, and 0.75, respectively, and for Indian mustard the Kc
values at the four growth stages are 0.3, 0.6, 1.12, and 0.35,
respectively. The second objective of the study is to compute daily
crop evapotranspiration from ET0 and crop coefficients. Average
daily ETc of maize varied from about 2.5 mm/d in the early growing
period to > 6.5 mm/d at mid season. The peak ETc of maize is 8.3
mm/d and it occurred 64 days after sowing at the reproductive growth
stage when leaf area index was 4.54. In the case of Indian mustard,
average ETc is 1 mm/d at the initial stage, >1.8 mm/d at mid season
and achieves a peak value of 2.12 mm/d on 56 days after sowing.
Improved schedules of irrigation have been simulated based on daily
crop evapo-transpiration and field measured data. Simulation shows a
close match between modeled and field moisture status prevalent
during crop season.
Abstract: This is a cross-cultural study that determines South
African multinational enterprises (MNEs) entry strategies as they
invest in Africa. An integrated theoretical framework comprising the
transaction cost theory, Uppsala model, eclectic paradigm and the
distance framework was adopted. A sample of 40 South African
MNEs with 415 existing FDI entries in Africa was drawn. Using an
ordered logistic regression model, the impact of culture on the choice
of degree of control by South African MNEs in Africa was
determined. Cultural distance was one of significant factors that
influenced South African MNEs- choice of degree of control.
Furthermore, South African MNEs are risk averse in all countries in
Africa but minimize the risks differently across sectors. Service
sectors chooses to own their subsidiaries 100% and avoid dealing
with the locals while manufacturing, resources and construction
choose to have a local partner to share the risk.
Abstract: The approach proposed here is oriented in the direction of fuzzy system for the analysis and the synthesis of intelligent climate controllers, the simulation of the internal climate of the greenhouse is achieved by a linear model whose coefficients are obtained by identification. The use of fuzzy logic controllers for the regulation of climate variables represents a powerful way to minimize the energy cost. Strategies of reduction and optimization are adopted to facilitate the tuning and to reduce the complexity of the controller.
Abstract: Renewed interest in propeller propulsion on aircraft
configurations combined with higher propeller loads lead to the question how the effects of the propulsion on model support disturbances
should be accounted for. In this paper, the determination of engine power effects on support interference of sting-mounted models is
demonstrated by a measurement on a four-engine turboprop aircraft.
CFD results on a more generic model are presented in order to clarify
the possible mechanism behind engine power effects on support
interference. The engine slipstream induces a local change in angle
of sideslip at the model sting thereby influencing the sting near-field and far-field effects. Whether or not the net result of these changes
in the disturbance pattern leads to a significant engine power effect depends on the configuration of the wind tunnel model and the test
setup.
Abstract: This paper presents a multi-objective order allocation
planning problem with the consideration of various real-world
production features. A novel hybrid intelligent optimization model,
integrating a multi-objective memetic optimization process, a Monte
Carlo simulation technique and a heuristic pruning technique, is
proposed to handle this problem. Experiments based on industrial data
are conducted to validate the proposed model. Results show that (1)
the proposed model can effectively solve the investigated problem by
providing effective production decision-making solutions, which
outperformsan NSGA-II-based optimization process and an industrial
method.
Abstract: This paper focuses on robust design and optimization
of industrial production wastes. Past literatures were reviewed to case
study Clamason Industries Limited (CIL) - a leading ladder-tops
manufacturer. A painstaking study of the firm-s practices at the shop
floor revealed that Over-production, Waiting time, Excess inventory,
and Defects are the major wastes that are impeding their progress and
profitability. Design expert8 software was used to apply Taguchi
robust design and response surface methodology in order to model,
analyse and optimise the wastes cost in CIL. Waiting time and overproduction
rank first and second in contributing to the costs of wastes
in CIL. For minimal wastes cost the control factors of overproduction,
waiting-time, defects and excess-inventory must be set at
0.30, 390.70, 4 and 55.70 respectively for CIL. The optimal value of
cost of wastes for the months studied was 22.3679. Finally, a
recommendation was made that for the company to enhance their
profitability and customer satisfaction, they must adopt the Shingeo
Shingo-s Single Minute Exchange of Dies (SMED), which will
immediately tackle the waste of waiting by drastically reducing their
setup time.
Abstract: This paper proposes a set of quasi-static mathematical
model of magnetic fields caused by high voltage conductors of
distribution transformer by using a set of second-order partial
differential equation. The modification for complex magnetic field
analysis and time-harmonic simulation are also utilized. In this
research, transformers were study in both balanced and unbalanced
loading conditions. Computer-based simulation utilizing the threedimensional
finite element method (3-D FEM) is exploited as a tool
for visualizing magnetic fields distribution volume a distribution
transformer. Finite Element Method (FEM) is one among popular
numerical methods that is able to handle problem complexity in
various forms. At present, the FEM has been widely applied in most
engineering fields. Even for problems of magnetic field distribution,
the FEM is able to estimate solutions of Maxwell-s equations
governing the power transmission systems. The computer simulation
based on the use of the FEM has been developed in MATLAB
programming environment.
Abstract: The paper presented a transient population dynamics of phase singularities in 2D Beeler-Reuter model. Two stochastic modelings are examined: (i) the Master equation approach with the transition rate (i.e., λ(n, t) = λ(t)n and μ(n, t) = μ(t)n) and (ii) the nonlinear Langevin equation approach with a multiplicative noise. The exact general solution of the Master equation with arbitrary time-dependent transition rate is given. Then, the exact solution of the mean field equation for the nonlinear Langevin equation is also given. It is demonstrated that transient population dynamics is successfully identified by the generalized Logistic equation with fractional higher order nonlinear term. It is also demonstrated the necessity of introducing time-dependent transition rate in the master equation approach to incorporate the effect of nonlinearity.
Abstract: The design of an active leg orthosis for tumble
protection is proposed in this paper. The orthosis would be applied to
assist elders or invalids in rebalancing while they fall unexpectedly.
We observe the regain balance motion of healthy and youthful people,
and find the difference to elders or invalids. First, the physical model
of leg would be established, and we consider the leg motions are
achieve through four joints (phalanx stem, ankle, knee, and hip joint)
and five links (phalanges, talus, tibia, femur, and hip bone). To
formulate the dynamic equations, the coordinates which can clearly
describe the position in 3D space are first defined accordance with the
human movement of leg, and the kinematics and dynamics of the leg
movement can be formulated based on the robotics. For the purpose,
assisting elders and invalids in avoiding tumble, the posture variation
of unbalance and regaining balance motion are recorded by the
motion-capture image system, and the trajectory is taken as the desire
one. Then we calculate the force and moment of each joint based on
the leg motion model through programming MATLAB code. The
results would be primary information of the active leg orthosis design
for tumble protection.
Abstract: The indistinctness of the manufacturing processes makes that a parts cannot be realized in an absolutely exact way towards the specifications on the dimensions. It is thus necessary to assume that the effectively realized product has to belong in a very strict way to compatible intervals with a correct functioning of the parts. In this paper we present an approach based on mixing tow different characteristics theories, the fuzzy system and Petri net system. This tool has been proposed to model and control the quality in an assembly system. A robust command of a mechanical assembly process is presented as an application. This command will then have to maintain the specifications interval of parts in front of the variations. It also illustrates how the technique reacts when the product quality is high, medium, or low.
Abstract: The interline power flow controller (IPFC) is one of
the latest generation flexible AC transmission systems (FACTS)
controller used to control power flows of multiple transmission lines.
This paper presents a mathematical model of IPFC, termed as power
injection model (PIM). This model is incorporated in Newton-
Raphson (NR) power flow algorithm to study the power flow control
in transmission lines in which IPFC is placed. A program in
MATLAB has been written in order to extend conventional NR
algorithm based on this model. Numerical results are carried out on a
standard 2 machine 5 bus system. The results without and with IPFC
are compared in terms of voltages, active and reactive power flows to
demonstrate the performance of the IPFC model.
Abstract: This paper deals with the thermo-mechanical deformation behavior of shear deformable functionally graded ceramicmetal (FGM) plates. Theoretical formulations are based on higher order shear deformation theory with a considerable amendment in the transverse displacement using finite element method (FEM). The mechanical properties of the plate are assumed to be temperaturedependent and graded in the thickness direction according to a powerlaw distribution in terms of the volume fractions of the constituents. The temperature field is supposed to be a uniform distribution over the plate surface (XY plane) and varied in the thickness direction only. The fundamental equations for the FGM plates are obtained using variational approach by considering traction free boundary conditions on the top and bottom faces of the plate. A C0 continuous isoparametric Lagrangian finite element with thirteen degrees of freedom per node have been employed to accomplish the results. Convergence and comparison studies have been performed to demonstrate the efficiency of the present model. The numerical results are obtained for different thickness ratios, aspect ratios, volume fraction index and temperature rise with different loading and boundary conditions. Numerical results for the FGM plates are provided in dimensionless tabular and graphical forms. The results proclaim that the temperature field and the gradient in the material properties have significant role on the thermo-mechanical deformation behavior of the FGM plates.
Abstract: In the previous multi-solid models,¤ò approach is
used for the calculation of fugacity in the liquid phase. For the first
time, in the proposed multi-solid thermodynamic model,γ approach
has been used for calculation of fugacity in the liquid mixture.
Therefore, some activity coefficient models have been studied that
the results show that the predictive Wilson model is more appropriate
than others. The results demonstrate γ approach using the predictive
Wilson model is in more agreement with experimental data than the
previous multi-solid models. Also, by this method, generates a new
approach for presenting stability analysis in phase equilibrium
calculations. Meanwhile, the run time in γ approach is less than the
previous methods used ¤ò approach. The results of the new model
present 0.75 AAD % (Average Absolute Deviation) from the
experimental data which is less than the results error of the previous
multi-solid models obviously.
Abstract: This study employs a bivariate asymmetric GARCH
model to reveal the hidden dynamics price changes and volatility
among the emerging markets of Thailand and Malaysian after the
Asian financial crisis from January 2001 to December 2008. Our
results indicated that the equity markets are sharing the common
information (shock) that transmitted among each others. These
empirical findings are used to demonstrate the importance of shock
and volatility dynamic transmissions in the cross-market hedging and
market risk.