Abstract: Batch production plants provide a wide range of
scheduling problems. In pharmaceutical industries a batch process
is usually described by a recipe, consisting of an ordering of tasks
to produce the desired product. In this research work we focused
on pharmaceutical production processes requiring the culture of
a microorganism population (i.e. bacteria, yeasts or antibiotics).
Several sources of uncertainty may influence the yield of the culture
processes, including (i) low performance and quality of the cultured
microorganism population or (ii) microbial contamination. For
these reasons, robustness is a valuable property for the considered
application context. In particular, a robust schedule will not collapse
immediately when a cell of microorganisms has to be thrown away
due to a microbial contamination. Indeed, a robust schedule should
change locally in small proportions and the overall performance
measure (i.e. makespan, lateness) should change a little if at all.
In this research work we formulated a constraint programming
optimization (COP) model for the robust planning of antibiotics
production. We developed a discrete-time model with a multi-criteria
objective, ordering the different criteria and performing a
lexicographic optimization. A feasible solution of the proposed
COP model is a schedule of a given set of tasks onto available
resources. The schedule has to satisfy tasks precedence constraints,
resource capacity constraints and time constraints. In particular
time constraints model tasks duedates and resource availability
time windows constraints. To improve the schedule robustness, we
modeled the concept of (a, b) super-solutions, where (a, b) are input
parameters of the COP model. An (a, b) super-solution is one in
which if a variables (i.e. the completion times of a culture tasks)
lose their values (i.e. cultures are contaminated), the solution can be
repaired by assigning these variables values with a new values (i.e.
the completion times of a backup culture tasks) and at most b other
variables (i.e. delaying the completion of at most b other tasks).
The efficiency and applicability of the proposed model is
demonstrated by solving instances taken from a real-life
pharmaceutical company. Computational results showed that
the determined super-solutions are near-optimal.
Abstract: The development of transport systems has negative
impacts on the environment although it has beneficial effects on
society. The car policy caused many problems such as: - the
spectacular growth of fuel consumption hence the very vast increase
in urban pollution, traffic congestion in certain places and at certain
times, the increase in the number of accidents. The exhaust emissions
from cars and weather conditions are the main factors that determine
the level of pollution in urban atmosphere. These conditions lead to
the phenomenon of heat transfer and radiation occurring between the
air and the soil surface of any town. These exchanges give rise, in
urban areas, to the effects of heat islands that correspond to the
appearance of excess air temperature between the city and its
surrounding space. In this object, we perform a numerical simulation
of the plume generated by the cars exhaust gases and show that these
gases form a screening effect above the urban city which cause the
heat island in the presence of wind flow. This study allows us: 1. To
understand the different mechanisms of interactions between these
phenomena.2. To consider appropriate technical solutions to mitigate
the effects of the heat island.
Abstract: This study analyzes the critical gaps in the
architecture of European stability and the expected role of the
banking union as the new important step towards completing the
Economic and Monetary Union that should enable the creation of
safe and sound financial sector for the euro area market. The single
rulebook together with the Single Supervisory Mechanism and the
Single Resolution Mechanism - as two main pillars of the banking
union, should provide a consistent application of common rules and
administrative standards for supervision, recovery and resolution of
banks – with the final aim of replacing the former bail-out practice
with the bail-in system through which possible future bank failures
would be resolved by their own funds, i.e. with minimal costs for
taxpayers and real economy. In this way, the vicious circle between
banks and sovereigns would be broken. It would also reduce the
financial fragmentation recorded in the years of crisis as the result of
divergent behaviors in risk premium, lending activities and interest
rates between the core and the periphery. In addition, it should
strengthen the effectiveness of monetary transmission channels, in
particular the credit channels and overflows of liquidity on the money
market which, due to the fragmentation of the common financial
market, has been significantly disabled in period of crisis. However,
contrary to all the positive expectations related to the future
functioning of the banking union, major findings of this study
indicate that characteristics of the economic system in which the
banking union will operate should not be ignored. The euro area is an
integration of strong and weak entities with large differences in
economic development, wealth, assets of banking systems, growth
rates and accountability of fiscal policy. The analysis indicates that
low and unbalanced economic growth remains a challenge for the
maintenance of financial stability and this problem cannot be
resolved just by a single supervision. In many countries bank assets
exceed their GDP by several times and large banks are still a matter
of concern, because of their systemic importance for individual
countries and the euro zone as a whole. The creation of the Single
Supervisory Mechanism and the Single Resolution Mechanism is a
response to the European crisis, which has particularly affected
peripheral countries and caused the associated loop between the
banking crisis and the sovereign debt crisis, but has also influenced
banks’ balance sheets in the core countries, as the result of crossborder
capital flows. The creation of the SSM and the SRM should
prevent the similar episodes to happen again and should also provide
a new opportunity for strengthening of economic and financial
systems of the peripheral countries. On the other hand, there is a
potential threat that future focus of the ECB, resolution mechanism
and other relevant institutions will be extremely oriented towards
large and significant banks (whereby one half of them operate in the
core and most important euro area countries), and therefore it remains
questionable to what extent will the common resolution funds will be used for rescue of less important institutions. Recent geopolitical
developments will be the optimal indicator to show whether the
previously established mechanisms are sufficient enough to maintain
the adequate financial stability in the euro area market.
Abstract: Nine Degrees of Freedom (9 DOF) systems are
already in development in many areas. In this paper, an integrated
pressure sensor is proposed that will make use of an already existing
monolithic 9 DOF inertial MEMS platform. Capacitive pressure
sensors can suffer from limited sensitivity for a given size of
membrane. This novel pressure sensor design increases the sensitivity
by over 5 times compared to a traditional array of square diaphragms
while still fitting within a 2 mm x 2 mm chip and maintaining a fixed
static capacitance. The improved design uses one large diaphragm
supported by pillars with fixed electrodes placed above the areas of
maximum deflection. The design optimization increases the
sensitivity from 0.22 fF/kPa to 1.16 fF/kPa. Temperature sensitivity
was also examined through simulation.
Abstract: In present global scenario, aluminum alloys are
coining the attention of many innovators as competing structural
materials for automotive and space applications. Comparing to other
challenging alloys, especially, 7xxx series aluminum alloys have
been studied seriously because of benefits such as moderate strength;
better deforming characteristics and affordable cost. It is expected
that substitution of aluminum alloys for steels will result in great
improvements in energy economy, durability and recyclability.
However, it is necessary to improve the strength and the formability
levels at low temperatures in aluminum alloys for still better
applications. Aluminum–Zinc–Magnesium with or without other
wetting agent denoted as 7XXX series alloys are medium strength
heat treatable alloys. In addition to Zn, Mg as major alloying
additions, Cu, Mn and Si are the other solute elements which
contribute for the improvement in mechanical properties by suitable
heat treatment process. Subjecting to suitable treatments like age
hardening or cold deformation assisted heat treatments; known as low
temperature thermomechanical treatments (LTMT) the challenging
properties might be incorporated. T6 is the age hardening or
precipitation hardening process with artificial aging cycle whereas T8
comprises of LTMT treatment aged artificially with X% cold
deformation. When the cold deformation is provided after solution
treatment, there is increase in hardness related properties such as
wear resistance, yield and ultimate strength, toughness with the
expense of ductility. During precipitation hardening both hardness
and strength of the samples are increasing. The hardness value may
further improve when room temperature deformation is positively
supported with age hardening known as thermomechanical treatment.
It is intended to perform heat treatment and evaluate hardness, tensile
strength, wear resistance and distribution pattern of reinforcement in
the matrix. 2 to 2.5 and 3 to 3.5 times increase in hardness is reported
in age hardening and LTMT treatments respectively as compared to
as-cast composite. There was better distribution of reinforcements in
the matrix, nearly two fold increase in strength levels and up to 5
times increase in wear resistance are also observed in the present
study.
Abstract: Numerical studies have been carried out using a
validated two-dimensional standard k-omega turbulence model for
the design optimization of a thrust vector control system using shock
induced self-impinging supersonic secondary double jet. Parametric
analytical studies have been carried out at different secondary
injection locations to identifying the highest unsymmetrical
distribution of the main gas flow due to shock waves, which produces
a desirable side force more lucratively for vectoring. The results from
the parametric studies of the case on hand reveal that the shock
induced self-impinging supersonic secondary double jet is more
efficient in certain locations at the divergent region of a CD nozzle
than a case with supersonic single jet with same mass flow rate. We
observed that the best axial location of the self-impinging supersonic
secondary double jet nozzle with a given jet interaction angle, built-in
to a CD nozzle having area ratio 1.797, is 0.991 times the primary
nozzle throat diameter from the throat location. We also observed
that the flexible steering is possible after invoking ON/OFF facility to
the secondary nozzles for meeting the onboard mission requirements.
Through our case studies we concluded that the supersonic self-impinging
secondary double jet at predesigned jet interaction angle
and location can provide more flexible steering options facilitating
with 8.81% higher thrust vectoring efficiency than the conventional
supersonic single secondary jet without compromising the payload
capability of any supersonic aerospace vehicle.
Abstract: This paper proposes a linear model for optimizing
domestic energy consumption in Romania. The particularity of the
model is that it is putting in competition both tangible technologies
and thermal insulation projects with different financing modes.
The model is optimizing the energy system by minimizing the
global discounted cost in household sector, by integrating residential
lighting, space heating, hot water, combined space heating – hot
water, as well as space cooling, in a monolithic model. Another
demand sector included is the passenger transport.
This paper focuses on space heating part, analyzing technical and
economic issues related to investment decisions to envelope and
insulate buildings, in order to minimize energy consumption.
Abstract: Due to the resultant leachate from waste
decomposition in landfills has polluter potential hundred times
greater than domestic sewage, this is considered a problem related to
the depreciation of environment requiring pre-disposal treatment.In
seeking to improve this situation, this project proposes the treatment
of landfill leachate using natural fibers intercropped with advanced
oxidation processes. The selected natural fibers were palm, coconut
and banana fiber.These materials give sustainability to the project
because, besides having adsorbent capacity, are often part of waste
discarded. The study was conducted in laboratory scale.In trials, the
effluents were characterized as Chemical Oxygen Demand (COD),
Turbidity and Color. The results indicate that is technically
promising since that there were extremely oxidative conditions, the
use of certain natural fibers in the reduction of pollutants in leachate
have been obtained results of COD removals between 67.9% and
90.9%, Turbidity between 88.0% and 99.7% and Color between
67.4% and 90.4%.The expectation generated is to continue evaluating
the association of efficiency of other natural fibers with other landfill
leachate treatment processes.
Abstract: Background: Delayed onset muscle soreness (DOMS)
is the most common symptom when ordinary individuals and athletes
are exposed to unaccustomed physical activity, especially eccentric
contraction which impairs athletic performance, ordinary people
work ability and physical functioning. Multitudes of methods have
been investigated to reduce DOMS. One of the valuable methods to
control DOMS is repeated bout effect (RBE) as a prophylactic
method. Purpose: To compare the repeated bout effect of
submaximal eccentric with maximal isometric contraction on induced
DOMS. Methods: Sixty normal male volunteers were assigned
randomly into three equal groups: Group A (first study group): 20
subjects received submaximal eccentric contraction on non-dominant
elbow flexors as a prophylactic exercise. Group B (second study
group): 20 subjects received maximal isometric contraction on nondominant
elbow flexors as a prophylactic exercise. Group C (control
group): 20 subjects did not receive any prophylactic exercises.
Maximal isometric peak torque of elbow flexors and patient related
elbow evaluation (PREE) scale were measured for each subject 3
times before, immediately after, and 48 hours after induction of
DOMS. Results: Post-hoc test for maximal isometric peak torque and
PREE scale immediately and 48 hours after induction of DOMS
revealed that group (A) and group (B) resulted in significant decrease
in maximal isometric strength loss and elbow pain and disability
rather than control group (C), but submaximal eccentric group (A)
was more effective than maximal isometric group (B) as it showed
more rapid recovery of functional strength and less degrees of elbow
pain and disability. Conclusion: Both submaximal eccentric
contraction and maximal isometric contraction were effective in
prevention of DOMS but submaximal eccentric contraction produced
a greater protective effect against muscle damage induced by
maximal eccentric exercise performed 2 days later.
Abstract: This paper represents the results of experimental work to investigate the suitability of a waste material (WM) for soft soil stabilisation. In addition, the effect of particle size distribution (PSD) of the waste material on its performance as a soil stabiliser was investigated. The WM used in this study is produced from the incineration processes in domestic energy power plant and it is available in two different grades of fineness (coarse waste material (CWM) and fine waste material (FWM)). An intermediate plasticity silty clayey soil with medium organic matter content has been used in this study. The suitability of the CWM and FWM to improve the physical and engineering properties of the selected soil was evaluated dependant on the results obtained from the consistency limits, compaction characteristics (optimum moisture content (OMC) and maximum dry density (MDD)); along with the unconfined compressive strength test (UCS). Different percentages of CWM were added to the soft soil (3, 6, 9, 12 and 15%) to produce various admixtures. Then the UCS test was carried out on specimens under different curing periods (zero, 7, 14, and 28 days) to find the optimum percentage of CWM. The optimum and other two percentages (either side of the optimum content) were used for FWM to evaluate the effect of the fineness of the WM on UCS of the stabilised soil. Results indicated that both types of the WM used in this study improved the physical properties of the soft soil where the index of plasticity (IP) was decreased significantly. IP was decreased from 21 to 13.64 and 13.10 with 12% of CWM and 15% of FWM respectively. The results of the unconfined compressive strength test indicated that 12% of CWM was the optimum and this percentage developed the UCS value from 202kPa to 500kPa for 28 days cured samples, which is equal, approximately 2.5 times the UCS value for untreated soil. Moreover, this percentage provided 1.4 times the value of UCS for stabilized soil-CWA by using FWM which recorded just under 700kPa after 28 days curing.
Abstract: This research aims to develop an algorithm to
generate a schedule of multiple cranes that will maximize load
throughputs in anodizing operation. The algorithm proposed utilizes
an enumerative strategy to search for constant time between
successive loads and crane covering range over baths. The computer
program developed is able to generate a near-optimal crane schedule
within reasonable times, i.e. within 10 minutes. Its results are
compared with existing solutions from an aluminum extrusion
industry. The program can be used to generate crane schedules for
mixed products, thus allowing mixed-model line balancing to
improve overall cycle times.
Abstract: The aim of this investigation is to elaborate nearinfrared
methods for testing and recognition of chemical components
and quality in “Pannon wheat” allied (i.e. true to variety or variety
identified) milling fractions as well as to develop spectroscopic
methods following the milling processes and evaluate the stability of
the milling technology by different types of milling products and
according to sampling times, respectively. These wheat categories
produced under industrial conditions where samples were collected
versus sampling time and maximum or minimum yields. The changes
of the main chemical components (such as starch, protein, lipid) and
physical properties of fractions (particle size) were analysed by
dispersive spectrophotometers using visible (VIS) and near-infrared
(NIR) regions of the electromagnetic radiation. Close correlation
were obtained between the data of spectroscopic measurement
techniques processed by various chemometric methods (e.g. principal
component analysis [PCA], cluster analysis [CA]) and operation
condition of milling technology. It is obvious that NIR methods are
able to detect the deviation of the yield parameters and differences of
the sampling times by a wide variety of fractions, respectively. NIR
technology can be used in the sensitive monitoring of milling
technology.
Abstract: Copper (I) oxide microparticles with the morphology
of cubic and hollow sphere were synthesized with the assistance of
surfactant as the shape controller. Both particles were then subjected
to study the catalytic activity and observed the results of shape effects
of catalysts on rate of catalytic reaction. The decolorizing reaction of
crystal violet and sodium hydroxide was chosen and measured the
decreasing of reactant with respect to times using spectrophotometer.
The result revealed that morphology of crystal had no effect on the
catalytic activity for crystal violet reaction but contributed to total
surface area predominantly.
Abstract: This study examines the feasibility of indirect solar
desalination in oil producing countries in the Middle East and North
Africa (MENA) region. It relies on value engineering (VE) and costbenefit
with sensitivity analyses to identify optimal coupling
configurations of desalination and solar energy technologies. A
comparative return on investment was assessed as a function of water
costs for varied plant capacities (25,000 to 75,000 m3/day), project
lifetimes (15 to 25 years), and discount rates (5 to 15%) taking into
consideration water and energy subsidies, land cost as well as
environmental externalities in the form of carbon credit related to
greenhouse gas (GHG) emissions reduction. The results showed
reverse osmosis (RO) coupled with photovoltaic technologies (PVs)
as the most promising configuration, robust across different prices for
Brent oil, discount rates, as well as different project lifetimes.
Environmental externalities and subsidies analysis revealed that a
16% reduction in existing subsidy on water tariffs would ensure
economic viability. Additionally, while land costs affect investment
attractiveness, the viability of RO coupled with PV remains possible
for a land purchase cost
Abstract: To mitigate the urban heat island effect has become a
global issue when we are faced with the challenge of climate change.
Through literature review, plant photosynthesis can reduce the carbon
dioxide and mitigate the urban heat island effect to a degree. Because
there are not enough open space and parks, green roof has become an
important policy in Taiwan.
We selected elementary school buildings in northern New Taipei
City as research subjects since elementary schools are asked with
priority to build green roof and important educational place to promote
green roof concept. Testo175-H1 recording device was used to record
the temperature and humidity differences between roof surface and
interior space below roof with and without green roof in the long-term.
We also use questionnaires to investigate the awareness of comfort
level of green roof and sensation of teachers and students of the
elementary schools.
The results indicated that the temperature of roof without greening
was higher than that with greening by about 2°C. But sometimes
during noontime, the temperature of green roof was higher than that of
non-green roof probably because of the character of the accumulation
and dissipation of heat of greening. The temperature of the interior
space below green roof was normally lower than that without green
roof by about 1°C, showing that green roof could lower the
temperature. The humidity of the green roof was higher than the one
without greening also indicated that green roof retained water better.
Teachers liked to combine green roof concept in the curriculum,
and students wished all classes can take turns to maintain the green
roof. Teachers and students whose school had integrated green roof
concept in the curriculum were more willing to participate in the
maintenance work of green roof. Teachers and students who may have
access to and touch the green roof can be more aware of the green roof
benefit. We suggest architects to increase the accessibility and
visibility of green roof, such as use it as a part of the activity space.
This idea can be a reference to the green roof curriculum design.
Abstract: The substantial development of the construction
industry has forced the cement industry, its major support, to focus
on achieving maximum productivity to meet the growing demand for
this material. This means that the reliability of a cement production
system needs to be at the highest level that can be achieved by good
maintenance. This paper studies the extent to which the
implementation of RCM is needed as a strategy for increasing the
reliability of the production systems component can be increased,
thus ensuring continuous productivity. In a case study of four Libyan
cement factories, 80 employees were surveyed and 12 top and middle
managers interviewed. It is evident that these factories usually
breakdown more often than once per month which has led to a
decline in productivity. In many times they cannot achieve the
minimum level of production amount. This has resulted from the
poor reliability of their production systems as a result of poor or
insufficient maintenance. It has been found that most of the factories’
employees misunderstand maintenance and its importance. The main
cause of this problem is the lack of qualified and trained staff, but in
addition it has been found that most employees are not found to be
motivated as a result of a lack of management support and interest. In
response to these findings, it has been suggested that the RCM
strategy should be implemented in the four factories. The results
show the importance of the development of maintenance strategies
through the implementation of RCM in these factories. The purpose
of it would be to overcome the problems that could secure the
reliability of the production systems. This study could be a useful
source of information for academic researchers and the industrial
organizations which are still experiencing problems in maintenance
practices.
Abstract: The rationale behind this study is considering
combating and preventing the phenomenon of trafficking in human
beings from a multidisciplinary perspective that involves many layers
of the society.
Trafficking in human beings is an abhorrent phenomenon highly
affecting negatively the victims and their families in both human and
material aspect, sometimes causing irreversible damages. The longer
term effects of this phenomenon, in countries with a weak economic
development and extremely young and dynamic population, such as
Kosovo, without proper measures to prevented and control can cause
tremendous damages in the society. Given the fact that a complete
eradication of this phenomenon is almost impossible, efforts should
be concentrated at least on the prevention and controlling aspects.
Treating trafficking in human beings based on traditional police
tactics, methods and proceedings cannot bring satisfactory results.
There is no doubt that a multi-disciplinary approach is an
irreplaceable requirement, in other words, a combination of authentic
and functional proactive and reactive methods, techniques and tactics.
Obviously, police must exercise its role in preventing and combating
trafficking in human beings, a role sanctioned by the law, however,
police role and contribution cannot by any means considered
complete if all segments of the society are not included in these
efforts. Naturally, civil society should have an important share in
these collaborative and interactive efforts especially in preventive
activities such as: awareness on trafficking risks and damages,
proactive engagement in drafting appropriate legislation and
strategies, law enforcement monitoring and direct or indirect
involvement in protective and supporting activities which benefit the
victims of trafficking etc.
Abstract: This paper addresses the design of hospital Intensive
Care Unit windows for the achievement of visual comfort and energy
savings. The aim was to identify the window size and shading system
configurations that could fulfill daylighting adequacy, avoid glare
and reduce energy consumption. The study focused on addressing the
effect of utilizing different shading systems in association with a
range of Window-to-Wall Ratios (WWR) in different orientations
under the desert clear-sky of Cairo, Egypt.
The results of this study demonstrated that solar penetration is a
critical concern affecting the design of ICU windows in desert
locations, as in Cairo, Egypt. Use of shading systems was found to be
essential in providing acceptable daylight performance and energy
saving. Careful positioning of the ICU window towards a proper
orientation can dramatically improve performance. It was observed
that ICU windows facing the north direction enjoyed the widest range
of successful window configuration possibilities at different WWRs.
ICU windows facing south enjoyed a reasonable number of
configuration options as well. By contrast, the ICU windows facing
the east orientation had a very limited number of options that provide
acceptable performance. These require additional local shading
measures at certain times due to glare incidence. Moreover, use of
horizontal sun breakers and solar screens to protect the ICU windows
proved to be more successful than the other alternatives in a wide
range of Window to Wall Ratios. By contrast, the use of light shelves
and vertical shading devices seemed questionable.
Abstract: An important problem for the CaSO4/CaSO4･1/2H2O
Chemical heat pump (CHP) is that the material is deactivated through
repetitive reaction between hydration and dehydration in which the
crystal phase of the material is transformed from III-CaSO4 to
II-CaSO4. We investigated suppression on the phase change by adding
a sulfated compound. The most effective material was MgSO4. MgSO4
doping increased the durability of CaSO4 in the actual CHP repetitive
cycle of hydration/dehydration to 3.6 times that of undoped CaSO4.
The MgSO4-doped CaSO4 showed a higher phase transition
temperature and activation energy for crystal transformation from
III-CaSO4 to II-CaSO4. MgSO4 doping decreased the crystal lattice
size of CaSO4･1/2H2O and II-CaSO4 to smaller than that of undoped
CaSO4. Modification of the crystal structure is considered to be related
to the durability change in CaSO4 resulting from MgSO4 doping.
Abstract: The paper deals with the classical fiber bundle model
of equal load sharing, sometimes referred to as the Daniels’ bundle
or the democratic bundle. Daniels formulated a multidimensional
integral and also a recursive formula for evaluation of the
strength cumulative distribution function. This paper describes
three algorithms for evaluation of the recursive formula and also
their implementations with source codes in the Python high-level
programming language. A comparison of the algorithms are provided
with respect to execution time. Analysis of orders of magnitudes of
addends in the recursion is also provided.