Abstract: An early diagnosis of bone metastasis is very
important for making a right decision on a subsequent therapy. One
of the most important steps to be taken initially, for developing a new
radiopharmaceutical is the measurement of organ radiation exposure
dose. In this study, the dosimetric studies of a novel agent for
SPECT-imaging of the bone metastasis, 111In-(4-
{[(bis(phosphonomethyl))carbamoyl]methyl}7,10bis(carboxymethyl)
-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (111In-BPAMD)
complex, have been carried out to estimate the dose in human organs
based on the data derived from mice. The radiolabeled complex was
prepared with high radiochemical purity in the optimal conditions.
Biodistribution studies of the complex was investigated in the male
Syrian mice at the selected times after injection (2, 4, 24 and 48 h).
The human absorbed dose estimation of the complex was made based
on data derived from the mice by the radiation absorbed dose
assessment resource (RADAR) method. 111In-BPAMD complex was prepared with high radiochemical
purity >95% (ITLC) and specific activities of 2.85 TBq/mmol. Total
body effective absorbed dose for 111In-BPAMD was 0.205
mSv/MBq. This value is comparable to the other 111In clinically used
complexes. The results show that the dose with respect to the critical
organs is satisfactory within the acceptable range for diagnostic
nuclear medicine procedures. Generally, 111In-BPAMD has
interesting characteristics and it can be considered as a viable agent
for SPECT-imaging of the bone metastasis in the near future.
Abstract: Countryside has been generally recognized and
regarded as a characteristic symbol which presents in human memory
for a long time. As a result of the change of times, because of it is
failure to meet the growing needs of the growing life and mental
decline, the vast rural area began to decline. But their history feature
image which accumulated by the ancient tradition provides people
with the origins of existence on the spiritual level, such as "identity"
and "belonging", makes people closer to the others in the spiritual and
psychological aspects of a common experience about the past, thus the
sense of a lack of culture caused by the losing of memory symbols is
weakened. So, in the modernization process, how to repair its vitality
and transform and planning it in a sustainable way has become a hot
topics in architectural and urban planning. This paper aims to break
the constraints of disciplines, from the perspective of interdiscipline,
using the research methods of systems science to analyze and discuss
the theories and methods of rural form factors, which based on the
viewpoint of memory in psychology. So we can find a right way to
transform the Rural to give full play to the role of the countryside in
the actual use and the shape of history spirits.
Abstract: In this paper, we propose two algorithms to optimally
solve makespan and total completion time scheduling problems with
learning effect and job dependent delivery times in a single machine
environment. The delivery time is the extra time to eliminate adverse
effect between the main processing and delivery to the customer. In
this paper, we introduce the job dependent delivery times for some
single machine scheduling problems with position dependent learning
effect, which are makespan are total completion. The results with
respect to two algorithms proposed for solving of the each problem
are compared with LINGO solutions for 50-jobs, 100-jobs and 150-
jobs problems. The proposed algorithms can find the same results in
shorter time.
Abstract: The paper shows that on transferring sense from the
SL to the TL, the translator’s reading against the grain determines the
creation of a faulty pattern of rendering the original meaning in the
receiving culture which reflects the use of misleading transformative
codes. In this case, the translator is a writer per se who decides what
goes in and out of the book, how the style is to be ciphered and what
elements of ideology are to be highlighted. The paper also proves that
figurative language must not be flattened for the sake of clarity or
naturalness. The missing figurative elements make the translated text
less interesting, less challenging and less vivid which reflects poorly
on the writer. There is a close connection between style and the
writer’s person. If the writer’s style is very much altered in a
translation, the translation is useless as the original writer and his /
her imaginative world can no longer be discovered. The purpose of the paper is to prove that adaptation is a dangerous
tool which leads to variants that sometimes reflect the original less
than the reader would wish to. It contradicts the very essence of the
process of translation which is that of making an original work
available in a foreign language. If the adaptive transformative codes
are so flexible that they encourage the translator to repeatedly leave
out parts of the original work, then a subversive pattern emerges
which changes the entire book. In conclusion, as a result of using adaptation, manipulative or
subversive effects are created in the translated work. This is generally
achieved by adding new words or connotations, creating new figures
of speech or using explicitations. The additional meanings of the
original work are neglected and the translator creates new meanings,
implications, emphases and contexts. Again s/he turns into a new
author who enjoys the freedom of expressing his / her own ideas
without the constraints of the original text. Reading against the grain
is unadvisable during the process of translation and consequently,
following personal common sense becomes essential in the field of
translation as well as everywhere else, so that translation should not
become a source of fantasy.
Abstract: The measurement of organ radiation exposure dose is
one of the most important steps to be taken initially, for developing a
new radiopharmaceutical. In this study, the dosimetric studies of a
novel agent for SPECT-imaging of the bone metastasis, 111In-
1,4,7,10-tetraazacyclododecane-1,4,7,10 tetraethylene phosphonic
acid (111In-DOTMP) complex, have been carried out to estimate the
dose in human organs based on the data derived from rats. The
radiolabeled complex was prepared with high radiochemical purity in
the optimal conditions. Biodistribution studies of the complex was
investigated in the male Syrian rats at selected times after injection
(2, 4, 24 and 48 h). The human absorbed dose estimation of the
complex was made based on data derived from the rats by the
radiation absorbed dose assessment resource (RADAR) method.
111In-DOTMP complex was prepared with high radiochemical purity
of >99% (ITLC). Total body effective absorbed dose for 111In-
DOTMP was 0.061 mSv/MBq. This value is comparable to the other
111In clinically used complexes. The results show that the dose with
respect to the critical organs is satisfactory within the acceptable
range for diagnostic nuclear medicine procedures. Generally, 111In-
DOTMP has interesting characteristics and can be considered as a
viable agent for SPECT-imaging of the bone metastasis in the near
future.
Abstract: This study was conducted to investigate the extent
with which knowledge of results influences the performance of
cricket players. A sample of 160 fresh students in the Department of
Physical and Health Education who are novice in the game were
randomly assigned into two groups. The first group of eighty (80)
subjects was classified as experimental group while the second group
of eighty (80) subjects was the control group. Subjects in both groups
were asked to bowl and bat ten times each for a period of six weeks.
After the first round, the subjects in the experimental group were
allowed feedback on their performance in the first trial while those in
the control group were denied feedback. Two null hypotheses
generated for the study were tested using percentages and chi-square
statistical analysis at 0.05 level of significance. Analysis of data
showed that knowledge of results influenced the performance of
cricket players. It was concluded that knowledge of results is
pertinent for effective skill acquisition and could enhance better
performance among unskilled cricket players. Hence, it is suggested
that immediate feedback on the level of skill acquisition by the
prospective and unskilled cricket players would inspire them for
better performance in cricket tournaments.
Abstract: Red pepper (Capsicum annum L.) has long been
recognized as a good source of antioxidants, being rich in ascorbic
acid and other phytochemicals. In Turkish cuisine red pepper is
sometimes consumed raw in salads and baked as a garnish, but its
most wide consumption type is red pepper paste. The processing of
red pepper into pepper paste includes various thermal treatment steps
such as heating and pasteurizing. There are reports demonstrating an
enhancement or reduction in antioxidant activity of vegetables after
thermal treatment. So this study was conducted to investigate the
total phenolic, ascorbic acid and total carotenoids as well as free
radical scavenging activity of raw red pepper and various red pepper
pastes obtainable on the market. The samples were analyzed for
radical-scavenging activity (RSA) and total polyphenol (TP) content
using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and Folin-Ciocalteu
methods, respectively. Total carotenoids and ascorbic acid contents
were determined spectrophotometrically. Results suggest that hot
pepper paste contained significantly (P0.05) difference in RSA, ascorbic acid and total carotenoids
content between sweet and hot red pepper paste products. It is
concluded that the red pepper paste, that has a wide range of
consumption in Turkish cuisine, presents a good dose of phenolic
compounds and antioxidant capacity and it should be regarded as a
functional food.
Abstract: Construction industry plays a vital role in the
economy of the world. However, due to high uncertainty and
variability in the industry, its performance is not as efficient in terms
of quality, lead times, productivity and costs as of other industries.
Moreover, there are continuous conflicts among the different actors
in the construction supply chains in terms of profit sharing. Previous
studies suggested partnership as an important approach to promote
cooperation among the different actors in the construction supply
chains and thereby it improves the overall performance. Construction
practitioners tried to focus on partnership which can enhance the
performance of construction supply chains but they are not fully
aware of different approaches and techniques for improving
partnership. In this research, a systematic review on partnership in
relation to construction supply chains is carried out to understand
different elements influencing the partnership. The research
development of this domain is analyzed by reviewing selected
articles published from 1996 to 2015. Based on the papers, three
major elements influencing partnership in construction supply chains
are identified: ‘Lean approach’, ‘Relationship building’ and ‘E-commerce
applications’. This study analyses the contributions in the
areas within each element and provides suggestions for future
developments of partnership in construction supply chains.
Abstract: The Radio Frequency Identification (RFID) technology
has a diverse base of applications, but it is also prone to security
threats. There are different types of security attacks which limit the
range of the RFID applications. For example, deploying the RFID
networks in insecure environments could make the RFID system
vulnerable to many types of attacks such as spoofing attack, location
traceability attack, physical attack and many more. Therefore, security
is often an important requirement for RFID systems. In this paper,
RFID mutual authentication protocol is implemented based on mobile
agent technology and timestamp, which are used to provide strong
authentication and integrity assurances to both the RFID readers and
their corresponding RFID tags. The integration of mobile agent
technology and timestamp provides promising results towards
achieving this goal and towards reducing the security threats in RFID
systems.
Abstract: Nonlinear evolution of broadband ultrasonic pulses
passed through the rock specimens is studied using the apparatus
“GEOSCAN-02M”. Ultrasonic pulses are excited by the pulses of Qswitched
Nd:YAG laser with the time duration of 10 ns and with the
energy of 260 mJ. This energy can be reduced to 20 mJ by some light
filters. The laser beam radius did not exceed 5 mm. As a result of the
absorption of the laser pulse in the special material – the optoacoustic
generator–the pulses of longitudinal ultrasonic waves are excited with
the time duration of 100 ns and with the maximum pressure
amplitude of 10 MPa. The immersion technique is used to measure
the parameters of these ultrasonic pulses passed through a specimen,
the immersion liquid is distilled water. The reference pulse passed
through the cell with water has the compression and the rarefaction
phases. The amplitude of the rarefaction phase is five times lower
than that of the compression phase. The spectral range of the
reference pulse reaches 10 MHz. The cubic-shaped specimens of the
Karelian gabbro are studied with the rib length 3 cm. The ultimate
strength of the specimens by the uniaxial compression is (300±10)
MPa. As the reference pulse passes through the area of the specimen
without cracks the compression phase decreases and the rarefaction
one increases due to diffraction and scattering of ultrasound, so the
ratio of these phases becomes 2.3:1. After preloading some horizontal
cracks appear in the specimens. Their location is found by one-sided
scanning of the specimen using the backward mode detection of the
ultrasonic pulses reflected from the structure defects. Using the
computer processing of these signals the images are obtained of the
cross-sections of the specimens with cracks. By the increase of the
reference pulse amplitude from 0.1 MPa to 5 MPa the nonlinear
transformation of the ultrasonic pulse passed through the specimen
with horizontal cracks results in the decrease by 2.5 times of the
amplitude of the rarefaction phase and in the increase of its duration
by 2.1 times. By the increase of the reference pulse amplitude from 5
MPa to 10 MPa the time splitting of the phases is observed for the
bipolar pulse passed through the specimen. The compression and
rarefaction phases propagate with different velocities. These features
of the powerful broadband ultrasonic pulses passed through the rock
specimens can be described by the hysteresis model of Preisach-
Mayergoyz and can be used for the location of cracks in the optically
opaque materials.
Abstract: Environmental and functional conditions, sometimes,
necessitate the architectural plan of the building to be asymmetric,
and this result in an asymmetric structure. In such cases finding an
optimal pattern for locating the components of lateral load bearing
system, including shear walls, in the building’s plan is desired. In
case of shear wall in addition to the location the shape of the wall
cross-section is also an effective factor. Various types of shear walls
and their proper layout might come effective in better stiffness
distribution and more appropriate seismic response of the building.
Several studies have been conducted in the context of analysis and
design of shear walls; however, few studies have been performed on
making decisions for the location and form of shear walls in multistory
buildings, especially those with irregular plan. In this study, an
attempt has been made to obtain the most reliable seismic behavior of
multi-story reinforced concrete vertically chamfered buildings by
using more appropriate shear walls form and arrangement in 7-, 10-,
12-, and 15-stoy buildings. The considered forms and arrangements
include common rectangular walls and L-, T-, U- and Z-shaped plan,
located as the core or in the outer frames of the building structure.
Comparison of seismic behaviors of the buildings, including
maximum roof displacement and particularly formation of plastic
hinges and their distribution in the buildings’ structures, have been
done based on the results of a series of nonlinear time history
analyses, by using a set of selected earthquake records. Results show
that shear walls with U-shaped cross-section, placed as the building
central core, and also walls with Z-shaped cross-section, placed at the
corners give the building more reliable seismic behavior.
Abstract: The apportionment method is used by many countries, to calculate the distribution of seats in political bodies. For example, this method is used in the United States (U.S.) to distribute house seats proportionally based on the population of the electoral district. Famous apportionment methods include the divisor methods called the Adams Method, Dean Method, Hill Method, Jefferson Method and Webster Method. Sometimes the results from the implementation of these divisor methods are unfair and include errors. Therefore, it is important to examine the optimization of this method by using a bias measurement to figure out precise and fair results. In this research we investigate the bias of divisor methods in the U.S. Houses of Representatives toward large and small states by applying the Stolarsky Mean Method. We compare the bias of the apportionment method by using two famous bias measurements: the Balinski and Young measurement and the Ernst measurement. Both measurements have a formula for large and small states. The Third measurement however, which was created by the researchers, did not factor in the element of large and small states into the formula. All three measurements are compared and the results show that our measurement produces similar results to the other two famous measurements.
Abstract: The seriously damaged structures during earthquakes
show the need and importance of design of reinforced concrete
structures with high ductility. Reinforced concrete beam-column
joints have an important function in all structures. Under seismic
excitation, the beam column joint region is subjected to horizontal
and vertical shear forces whose magnitude is many times higher than
the adjacent beam and column. Strength and ductility of structures
depends mainly on proper detailing of the reinforcement in beamcolumn
joints and the old structures were found ductility deficient.
DSP materials are obtained by using high quantities of super
plasticizers and high volumes of micro silica. In the case of High
Performance Densified Small Particle Concrete (HPDSPC), since
concrete is dense even at the micro-structure level, tensile strain
would be much higher than that of the conventional SFRC, SIFCON
& SIMCON. This in turn will improve cracking behaviour, ductility
and energy absorption capacity of composites in addition to
durability. The fine fibers used in our mix are 0.3mm diameter and 10
mm which can be easily placed with high percentage. These fibers
easily transfer stresses and act as a composite concrete unit to take up
extremely high loads with high compressive strength. HPDSPC
placed in the beam column joints helps in safety of human life due to
prolonged failure.
Abstract: Networked environments which provide platforms for
business organizations are configured in different forms depending
on many factors including life time, member characteristics,
communication structure, and business objectives, among others.
With continuing advances in digital technologies the distance has
become a less barrier for business minded collaboration among
organizations. With the need and ease to make business collaborate
nowadays organizations are sometimes forced to co-work with others
that are either unknown or less known to them in terms of history and
performance. A promising approach for sustaining established
collaboration has been establishment of trust relationship among
organizations based on assessed trustworthiness for each participating
organization. It has been stated in research that trust in organization is
dynamic and thus assessment of trust level must address such
dynamic nature. This paper assesses relevant aspects of trust and
applies the assessed concepts to propose a semi-automated system for
the management of Sustainability and Evolution of trust in
organizations participating in specific objective in a networked
organizations environment.
Abstract: High temperature Fischer-Tropsch synthesis process
use fixed fluidized bed as a reactor. In order to understand the flow
behavior in the fluidized bed better, the research of how the radial
velocity affects the entire flow field is necessary. Laser Doppler
Velocimetry (LDV) was used to study the radial velocity distribution
along the diameter direction of the cross-section of the particle in a
fixed fluidized bed. The velocity in the cross-section is fluctuating
within a small range. The direction of the speed is a random
phenomenon. In addition to r/R is 1, the axial velocity are more than 6
times of the radial velocity, the radial velocity has little impact on the
axial velocity in a fixed fluidized bed.
Abstract: The current study aims to highlight the loading
characteristics impact on the time evolution (focusing particularly on
long term effects) of the deformation of realized reinforced concrete
beams. Namely the tension stiffening code provisions (i.e. within
Eurocode 2) are reviewed with a clear intention to reassess their
operational value and predicting capacity. In what follows the
experimental programme adopted along with some preliminary
findings and numerical modeling attempts are presented. For a range of long slender reinforced concrete simply supported
beams (4200 mm) constant static sustained and repeated cyclic
loadings were applied mapping the time evolution of deformation.
All experiments were carried out at the Heavy Structures Lab of the
University of Leeds. During tests the mid-span deflection, creep
coefficient and shrinkage strains were monitored for duration of 90
days. The obtained results are set against the values predicted by
Eurocode 2 and the tools within an FE commercial package (i.e.
Midas FEA) to yield that existing knowledge and practise is at times
over-conservative.
Abstract: This paper presents the modeling approach in SBO
sequence for VVER 1000 reactors and describes the reactor core
behavior at late in-vessel phase in case of late reflooding by HPIS
and gives preliminary results for the ASTECv2 validation. The work
is focused on investigation of plant behavior during total loss of
power and the operator actions. The main goal of these analyses is to
assess the phenomena arising during the Station blackout (SBO)
followed by primary side high pressure injection system (HPIS)
reflooding of already damaged reactor core at very late “in-vessel”
phase. The purpose of the analyses is to define how the later HPIS
switching on can delay the time of vessel failure or possibly avoid
vessel failure. The times for HPP injection were chosen based on
previously performed investigations.
Abstract: This paper will discuss how we optimize our physical
verification flow in our IC Design Department having various rule
decks from multiple foundries. Our ultimate goal is to achieve faster
time to tape-out and avoid schedule delay. Currently the physical
verification runtimes and memory usage have drastically increased
with the increasing number of design rules, design complexity, and
the size of the chips to be verified. To manage design violations, we
use a number of solutions to reduce the amount of violations needed
to be checked by physical verification engineers. The most important
functions in physical verifications are DRC (design rule check), LVS
(layout vs. schematic), and XRC (extraction). Since we have a
multiple number of foundries for our design tape-outs, we need a
flow that improve the overall turnaround time and ease of use of the
physical verification process. The demand for fast turnaround time is
even more critical since the physical design is the last stage before
sending the layout to the foundries.
Abstract: The current tools for real time management of sewer
systems are based on two software tools: the software of weather
forecast and the software of hydraulic simulation. The use of the first
ones is an important cause of imprecision and uncertainty, the use of
the second requires temporal important steps of decision because of
their need in times of calculation. This way of proceeding fact that
the obtained results are generally different from those waited. The major idea of this project is to change the basic paradigm by
approaching the problem by the "automatic" face rather than by that
"hydrology". The objective is to make possible the realization of a
large number of simulations at very short times (a few seconds)
allowing to take place weather forecasts by using directly the real
time meditative pluviometric data. The aim is to reach a system
where the decision-making is realized from reliable data and where
the correction of the error is permanent. A first model of control laws was realized and tested with different
return-period rainfalls. The gains obtained in rejecting volume vary
from 19 to 100 %. The development of a new algorithm was then
used to optimize calculation time and thus to overcome the
subsequent combinatorial problem in our first approach. Finally, this
new algorithm was tested with 16- year-rainfall series. The obtained
gains are 40 % of total volume rejected to the natural environment
and of 65 % in the number of discharges.
Abstract: It is the patient compliance and stability in
combination with controlled drug delivery and biocompatibility that
forms the core feature in present research and development of
sustained biodegradable patch formulation intended for wound
healing. The aim was to impart sustained degradation, sterile
formulation, significant folding endurance, elasticity,
biodegradability, bio-acceptability and strength. The optimized
formulation comprised of polymers including Hydroxypropyl methyl
cellulose, Ethylcellulose, and Gelatin, and Citric Acid PEG Citric
acid (CPEGC) triblock dendrimers and active Curcumin. Polymeric
mixture dissolved in geometric order in suitable medium through
continuous stirring under ambient conditions. With continued stirring
Curcumin was added with aid of DCM and Methanol in optimized
ratio to get homogenous dispersion. The dispersion was sonicated
with optimum frequency and for given time and later casted to form a
patch form. All steps were carried out under strict aseptic conditions.
The formulations obtained in the acceptable working range were
decided based on thickness, uniformity of drug content, smooth
texture and flexibility and brittleness. The patch kept on stability
using butter paper in sterile pack displayed folding endurance in
range of 20 to 23 times without any evidence of crack in an
optimized formulation at room temperature (RT) (24 ± 2°C). The
patch displayed acceptable parameters after stability study conducted
in refrigerated conditions (8±0.2°C) and at RT (24 ± 2°C) up to 90
days. Further, no significant changes were observed in critical
parameters such as elasticity, biodegradability, drug release and drug
content during stability study conducted at RT 24±2°C for 45 and 90
days. The drug content was in range 95 to 102%, moisture content
didn’t exceeded 19.2% and patch passed the content uniformity test.
Percentage cumulative drug release was found to be 80% in 12h and
matched the biodegradation rate as drug release with correlation
factor R2>0.9. The biodegradable patch based formulation developed
shows promising results in terms of stability and release profiles.