Abstract: In a 10-week (May – August, 2008) Phase I trial, 840, 1+ rainbow trout, Oncorhynchus mykiss, received a commercial oral immunomodulator, Fin Immune™, at four different dosages (0, 10, 20 and 30 mg g-1) to evaluate immune response and growth. The overall objective of was to determine an optimal dosage of this product for rainbow trout that provides enhanced immunity with maximal growth and health. Biweekly blood samples were taken from 10 randomly selected fish in each tank (30 samples per treatment) to evaluate the duration of enhanced immunity conferred by Fin-Immune™. The immunological assessment included serum white blood cell (lymphocyte, neutrophil) densities and blood hematocrit (packed cell volume %). Of these three variables, only lymphocyte density increased significantly among trout fed Fin- Immune™ at 20 and 30 mg g-1 which peaked at week 6. At week 7, all trout were switched to regular feed (lacking Fin-Immune™) and by week 10, lymphocyte levels decreased among all levels but were still greater than at week 0. There was growth impairment at the highest dose of Fin-Immune™ tested (30 mg g-1) which can be associated with a physiological compensatory mechanism due to a dose-specific threshold level. Thus, our main objective of this Phase I study was achieved, the 20 mg g-1 dose of Fin-Immune™ should be the most efficacious (of those we tested) to use for a Phase II disease challenge trial.
Abstract: In view of growing competition in the service sector,
services are as much in need of modeling, analysis and improvement
as business or working processes. Graphical process models are
important means to capture process-related know-how for an
effective management of the service process. In this contribution, a
human performance analysis of process model development paying
special attention to model development time and the working method
was conducted. It was found that modelers with higher application
experience need significantly less time for mental activities than
modelers with lower application experience, spend more time on
labeling graphical elements, and achieved higher process model
quality in terms of activity label quality.
Abstract: A novel feature selection strategy to improve the recognition accuracy on the faces that are affected due to nonuniform illumination, partial occlusions and varying expressions is proposed in this paper. This technique is applicable especially in scenarios where the possibility of obtaining a reliable intra-class probability distribution is minimal due to fewer numbers of training samples. Phase congruency features in an image are defined as the points where the Fourier components of that image are maximally inphase. These features are invariant to brightness and contrast of the image under consideration. This property allows to achieve the goal of lighting invariant face recognition. Phase congruency maps of the training samples are generated and a novel modular feature selection strategy is implemented. Smaller sub regions from a predefined neighborhood within the phase congruency images of the training samples are merged to obtain a large set of features. These features are arranged in the order of increasing distance between the sub regions involved in merging. The assumption behind the proposed implementation of the region merging and arrangement strategy is that, local dependencies among the pixels are more important than global dependencies. The obtained feature sets are then arranged in the decreasing order of discriminating capability using a criterion function, which is the ratio of the between class variance to the within class variance of the sample set, in the PCA domain. The results indicate high improvement in the classification performance compared to baseline algorithms.
Abstract: Supply network management adopts a systematic
and integrative approach to managing the operations and
relationships of various parties in a supply network. The objective
of the manufactures in their supply network is to reduce inventory
costs and increase customer satisfaction levels. One way of doing
that is to synchronize delivery performance. A supply network can
be described by nodes representing the companies and the links
(relationships) between these nodes. Uncertainty in delivery time
depends on type of network relationship between suppliers. The
problem is to understand how the individual uncertainties influence
the total uncertainty of the network and identify those parts of the
network, which has the highest potential for improving the total
delivery time uncertainty.
Abstract: Periodicities in the environmetric time series can be
idyllically assessed by utilizing periodic models. In this
communication fugitive emission of gases from open sewer channel
Lyari which follows periodic behaviour are approximated by
employing periodic autoregressive model of order p. The orders of
periodic model for each season are selected through the examination
of periodic partial autocorrelation or information criteria. The
parameters for the selected order of season are estimated individually
for each emitted air toxin. Subsequently, adequacies of fitted models
are established by examining the properties of the residual for each
season. These models are beneficial for schemer and administrative
bodies for the improvement of implemented policies to surmount
future environmental problems.
Abstract: Iris-based biometric authentication is gaining importance
in recent times. Iris biometric processing however, is a complex
process and computationally very expensive. In the overall processing
of iris biometric in an iris-based biometric authentication system,
feature processing is an important task. In feature processing, we extract
iris features, which are ultimately used in matching. Since there
is a large number of iris features and computational time increases
as the number of features increases, it is therefore a challenge to
develop an iris processing system with as few as possible number of
features and at the same time without compromising the correctness.
In this paper, we address this issue and present an approach to feature
extraction and feature matching process. We apply Daubechies D4
wavelet with 4 levels to extract features from iris images. These
features are encoded with 2 bits by quantizing into 4 quantization
levels. With our proposed approach it is possible to represent an
iris template with only 304 bits, whereas existing approaches require
as many as 1024 bits. In addition, we assign different weights to
different iris region to compare two iris templates which significantly
increases the accuracy. Further, we match the iris template based on
a weighted similarity measure. Experimental results on several iris
databases substantiate the efficacy of our approach.
Abstract: Skin color can provide a useful and robust cue
for human-related image analysis, such as face detection,
pornographic image filtering, hand detection and tracking,
people retrieval in databases and Internet, etc. The major
problem of such kinds of skin color detection algorithms is
that it is time consuming and hence cannot be applied to a real
time system. To overcome this problem, we introduce a new
fast technique for skin detection which can be applied in a real
time system. In this technique, instead of testing each image
pixel to label it as skin or non-skin (as in classic techniques),
we skip a set of pixels. The reason of the skipping process is
the high probability that neighbors of the skin color pixels are
also skin pixels, especially in adult images and vise versa. The
proposed method can rapidly detect skin and non-skin color
pixels, which in turn dramatically reduce the CPU time
required for the protection process. Since many fast detection
techniques are based on image resizing, we apply our
proposed pixel skipping technique with image resizing to
obtain better results. The performance evaluation of the
proposed skipping and hybrid techniques in terms of the
measured CPU time is presented. Experimental results
demonstrate that the proposed methods achieve better result
than the relevant classic method.
Abstract: The present study was carried out to evaluate the
nutritional value of sorghum flour during processing of injera
(unleavened thick bread). The proximate composition of sorghum
flour before and after fermentation and that of injera was determined.
Compared to the raw flour and fermented one, injera had low protein
(11.55%), ash (1.57%) and fat (2.40%) contents but high in fiber
content. Moreover, injera was found to have significantly (P ≤ 0.05)
higher energy (389.08 Kcal/100g) compared to raw and fermented
sorghum flour. Injera contained lower levels of anti-nutritional
factors (polyphenols, phytate and tannins) compared to raw and
fermented sorghum. Also it was found to be rich in Ca
(4.75mg/100g), Fe (3.95 mg/100g), and Cu (0.7 mg/100g) compared
to that of raw and fermented flour. Moreover, both the extractable
minerals and protein digestibility were high for injera due to low
amount of anti-nutrients. Injera was found to contain an appreciable
amount of amino acids except arginine and tyrosine.
Abstract: The effect of cross linking of the protein isolates of
three legumes with the microbial enzyme transglutaminase (EC
2.3.2.13) on the functional properties at different NaCl concentration
was studied. The reduction in the total free amino groups (OD340) of
the polymerized protein showed that TGase treatment cross-linking
the protein subunit of each legume. The solubility of the protein
polymer of each legume was greatly improved at high concentration
of NaCl. At 1.2 M NaCl the solubility of the native legumes protein
was significantly decreased but after polymerization slightly
improved. Cross linked proteins were less turbid on heating to higher
temperature as compared to native proteins and the temperature at
which the protein turns turbid also increased in the polymerized
proteins. The emulsifying and foaming properties of the protein
polymer were greatly improved at all concentrations of NaCl for all
legumes.
Abstract: The Constraints imposed by non-thermal
leptogenesis on the survival of the neutrino mass models describing
the presently available neutrino mass patterns, are studied
numerically. We consider the Majorana CP violating phases coming
from right-handed Majorana mass matrices to estimate the baryon
asymmetry of the universe, for different neutrino mass models
namely quasi-degenerate, inverted hierarchical and normal
hierarchical models, with tribimaximal mixings. Considering two
possible diagonal forms of Dirac neutrino mass matrix as either
charged lepton or up-quark mass matrix, the heavy right-handed
mass matrices are constructed from the light neutrino mass matrix.
Only the normal hierarchical model leads to the best predictions of
baryon asymmetry of the universe, consistent with observations in
non-thermal leptogenesis scenario.
Abstract: In a representative democracy political parties
promote vital competition on different policy issues and play
essential roles by offering ideological alternatives. They also give
channels for citizens- participation in government decision-making
processes and they are significant conduits and interpreters of
information about government. This paper attempts to examine how
opposition political parties and rebel fronts emerged in Ethiopia, and
examines their present conditions. In this paper, selected case studies
of political parties and rebel fronts are included to highlight the status
and the role of opposition groups in the country in the three
successive administrations: Haile Selassie (1930-1974), Derg (1974-
1991), and EPRDF (1991-Present).
Abstract: Palm methyl ester (PME) is one of the alternative
biomass fuels to liquid fossil fuels. To investigate the combustion
characteristics of PME as an alternative fuel for gas turbines, combustion experiments using two types of burners under atmospheric
pressure were performed. One of the burners has a configuration
making strong non-premixed flame, whereas the other has a
configuration promoting prevaporization of fuel droplets. The results
show that the NOx emissions can be reduced by employing the latter burner without accumulation of soot when PME is used as a fuel. A
burner configuration promoting prevaporzation of fuel droplets is
recommended for PME.
Abstract: Social-economic variables influence transportation
demand largely. Analyses of discrete choice model consider
social-economic variables to study traveler-s mode choice and
demand. However, to calibrate the discrete choice model needs to have
plenty of questionnaire survey. Also, an aggregative model is
proposed. The historical data of passenger volumes for high speed rail
and domestic civil aviation are employed to calibrate and validate the
model. In this study, models with different social-economic variables,
which are oil price, GDP per capita, CPI and economic growth rate,
are compared. From the results, the model with the oil price is better
than models with the other social-economic variables.
Abstract: The success of an electronic system in a System-on- Chip is highly dependent on the efficiency of its interconnection network, which is constructed from routers and channels (the routers move data across the channels between nodes). Since neither classical bus based nor point to point architectures can provide scalable solutions and satisfy the tight power and performance requirements of future applications, the Network-on-Chip (NoC) approach has recently been proposed as a promising solution. Indeed, in contrast to the traditional solutions, the NoC approach can provide large bandwidth with moderate area overhead. The selected topology of the components interconnects plays prime rule in the performance of NoC architecture as well as routing and switching techniques that can be used. In this paper, we present two generic NoC architectures that can be customized to the specific communication needs of an application in order to reduce the area with minimal degradation of the latency of the system. An experimental study is performed to compare these structures with basic NoC topologies represented by 2D mesh, Butterfly-Fat Tree (BFT) and SPIN. It is shown that Cluster mesh (CMesh) and MinRoot schemes achieves significant improvements in network latency and energy consumption with only negligible area overhead and complexity over existing architectures. In fact, in the case of basic NoC topologies, CMesh and MinRoot schemes provides substantial savings in area as well, because they requires fewer routers. The simulation results show that CMesh and MinRoot networks outperforms MESH, BFT and SPIN in main performance metrics.
Abstract: In this study, a novel approach of image embedding is introduced. The proposed method consists of three main steps. First, the edge of the image is detected using Sobel mask filters. Second, the least significant bit LSB of each pixel is used. Finally, a gray level connectivity is applied using a fuzzy approach and the ASCII code is used for information hiding. The prior bit of the LSB represents the edged image after gray level connectivity, and the remaining six bits represent the original image with very little difference in contrast. The proposed method embeds three images in one image and includes, as a special case of data embedding, information hiding, identifying and authenticating text embedded within the digital images. Image embedding method is considered to be one of the good compression methods, in terms of reserving memory space. Moreover, information hiding within digital image can be used for security information transfer. The creation and extraction of three embedded images, and hiding text information is discussed and illustrated, in the following sections.
Abstract: Acute toxicity of nano SiO2, ZnO, MCM-41 (Meso
pore silica), Cu, Multi Wall Carbon Nano Tube (MWCNT), Single
Wall Carbon Nano Tube (SWCNT) , Fe (Coated) to bacteria Vibrio
fischeri using a homemade luminometer , was evaluated. The values
of the nominal effective concentrations (EC), causing 20% and 50%
inhibition of biouminescence, using two mathematical models at two
times of 5 and 30 minutes were calculated. Luminometer was
designed with Photomultiplier (PMT) detector. Luminol
chemiluminescence reaction was carried out for the calibration graph.
In the linear calibration range, the correlation coefficients and
coefficient of Variation (CV) were 0.988 and 3.21% respectively
which demonstrate the accuracy and reproducibility of the instrument
that are suitable. The important part of this research depends on how
to optimize the best condition for maximum bioluminescence. The
culture of Vibrio fischeri with optimal conditions in liquid media,
were stirring at 120 rpm at a temperature of 150C to 180C and were
incubated for 24 to 72 hours while solid medium was held at 180C
and for 48 hours. Suspension of nanoparticles ZnO, after 30 min
contact time to bacteria Vibrio fischeri, showed the highest toxicity
while SiO2 nanoparticles showed the lowest toxicity. After 5 min
exposure time, the toxicity of ZnO was the strongest and MCM-41
was the weakest toxicant component.
Abstract: Inflammatory bowel disease (IBD) is a chronic
relapsing-remitting condition that afflicts millions of people
throughout the world and impairs their daily functions and quality of
life. Treatment of IBD depends largely on 5-aminosalicylic acid (5-
ASA) and corticosteroids. The present study aimed to clarify the
effects of 5-aminosalicylic acid, budesonide and currcumin on 90
male albino rats against trinitrobenzene sulfonic acid (TNB) induced
colitis. TNB was injected intrarectally to 50 rats. The other 40 rats
served as control groups. Both 5-ASA (in a dose of 120 mg/kg) and
budesonide (in a dose of 0.1 mg/kg) were administered daily for one
week whereas currcumin was injected intraperitonially (in a dose of
30 mg/kg daily) for 14 days after injection of either TNB in the
colitis rats (group B) or saline in control groups (group A). The study
included estimation of macroscopic score index, histological
examination of H&E stained sections of the colonic tissue,
biochemical estimation of myeloperoxidase (MPO), nitric oxide
(NO), and caspase-3 levels, in addition to studying the effect of tested
drugs on colonic motility. It was found that budesonide and curcumin
improved mucosal healing, reduced both NO production and caspase-
3 level. They had the best impact on the disturbed colonic motility in
TNBS-model of colitis.
Abstract: Verapamil has been shown to inhibit fentanyl uptake in vitro and is a potent P-glycoprotein inhibitor. Tissue partitioning of loperamide, a commercially available opioid, is closely controlled by the P-gp efflux transporter. The following studies were designed to evaluate the effect of opioids on verapamil partitioning in the lung and brain, in vivo. Opioid (fentanyl or loperamide) was administered by intravenous infusion to Sprague Dawley rats alone or in combination with verapamil and plasma, with lung and brain tissues were collected at 1, 5, 6, 8, 10 and 60 minutes. Drug dispositions were modeled by recirculatory pharmacokinetic models. Fentanyl slightly increased the verapamil lung (PL) partition coefficient yet decreased the brain (PB) partition coefficient. Furthermore, loperamide significantly increased PLand PB. Fentanyl reduced the verapamil volume of distribution (V1) and verapamil elimination clearance (ClE). Fentanyl decreased verapamil brain partitioning, yet increased verapamil lung partitioning. Also, loperamide increased lung and brain partitioning in vivo. These results suggest that verapamil and fentanyl may be substrates of an unidentified inward transporter in brain tissue and confirm that verapamil and loperamide are substrates of the efflux transporter P-gp.
Abstract: We present a numerical study of the sensitivity of the so called time relaxation family of models of fluid motion with respect to the time relaxation parameter χ on the two dimensional cavity problem. The goal of the study is to compute and compare the sensitivity of the model using finite difference method (FFD) and sensitivity equation method (SEM).
Abstract: Reachability graph (RG) generation suffers from the
problem of exponential space and time complexity. To alleviate the
more critical problem of time complexity, this paper presents the new
approach for RG generation for the Petri net (PN) models of parallel
processes. Independent RGs for each parallel process in the PN
structure are generated in parallel and cross-product of these RGs
turns into the exhaustive state space from which the RG of given
parallel system is determined. The complexity analysis of the
presented algorithm illuminates significant decrease in the time
complexity cost of RG generation. The proposed technique is
applicable to parallel programs having multiple threads with the
synchronization problem.