Abstract: Predicting protein-protein interactions represent a key step in understanding proteins functions. This is due to the fact that proteins usually work in context of other proteins and rarely function alone. Machine learning techniques have been applied to predict protein-protein interactions. However, most of these techniques address this problem as a binary classification problem. Although it is easy to get a dataset of interacting proteins as positive examples, there are no experimentally confirmed non-interacting proteins to be considered as negative examples. Therefore, in this paper we solve this problem as a one-class classification problem using one-class support vector machines (SVM). Using only positive examples (interacting protein pairs) in training phase, the one-class SVM achieves accuracy of about 80%. These results imply that protein-protein interaction can be predicted using one-class classifier with comparable accuracy to the binary classifiers that use artificially constructed negative examples.
Abstract: Knowledge management (KM) is generally
considered to be a positive process in an organisation, facilitating
opportunities to achieve competitive advantage via better quality
information handling, compilation of expert know-how and rapid
response to fluctuations in the business environment. The KM
paradigm as portrayed in the literature informs the processes that can
increase intangible assets so that corporate knowledge is preserved.
However, in some instances, knowledge management exists in a
universe of dynamic tension among the conflicting needs to respect
privacy and intellectual property (IP), to guard against data theft, to
protect national security and to stay within the laws. While the
Knowledge Management literature focuses on the bright side of the
paradigm, there is also a different side in which knowledge is
distorted, suppressed or misappropriated due to personal or
organisational motives (the paradox). This paper describes the ethical
paradoxes that occur within the taxonomy and deontology of
knowledge management and suggests that recognising both the
promises and pitfalls of KM requires wisdom.
Abstract: Given a bivariate normal sample of correlated variables,
(Xi, Yi), i = 1, . . . , n, an alternative estimator of Pearson’s correlation
coefficient is obtained in terms of the ranges, |Xi − Yi|.
An approximate confidence interval for ρX,Y is then derived, and
a simulation study reveals that the resulting coverage probabilities
are in close agreement with the set confidence levels. As well, a
new approximant is provided for the density function of R, the
sample correlation coefficient. A mixture involving the proposed
approximate density of R, denoted by hR(r), and a density function
determined from a known approximation due to R. A. Fisher is shown
to accurately approximate the distribution of R. Finally, nearly exact
density approximants are obtained on adjusting hR(r) by a 7th degree
polynomial.
Abstract: In this work, a characterization and modeling of
packet loss of a Voice over Internet Protocol (VoIP) communication
is developed. The distributions of the number of consecutive received
and lost packets (namely gap and burst) are modeled from the
transition probabilities of two-state and four-state model.
Measurements show that both models describe adequately the burst
distribution, but the decay of gap distribution for non-homogeneous
losses is better fit by the four-state model. The respective
probabilities of transition between states for each model were
estimated with a proposed algorithm from a set of monitored VoIP
calls in order to obtain representative minimum, maximum and
average values for both models.
Abstract: People have always needed to believe in some
supernatural power, which could explain nature phenomena.
Different kinds of religions like Christianity, Hinduism, Islam,
Buddhism have thought believers in all world, how to behave
themselves. We think the most important role of religion in modern
society most important role of religion in modern society is safety of
the People. World and traditional religion played a prominent role in
the socio-cultural progress, and in the development of man as a
spiritual being. At the heart of religious morals the belief in god and
responsibility before it lies and specifies religious and ethical values
and categories . The religion is based on ethical standards historically
developed by society, requirements and concepts, but it puts all
social and moral relations of the person in dependence on religious
values. For everything that the believer makes on a debt or a duty, he
bears moral responsibility before conscience, people and god. The
concept of value of religious morals takes the central place because
the religion from all forms of public consciousness most values is
painted as it is urged to answer vital questions. Any religion not only
considers questions of creation of the world, sense of human
existence, relationship of god and the person, but also offers the
ethical concept, develops rules of behavior of people. The religion a
long time dominated in the history of culture, and during this time
created a set of cultural and material values. The identity of Kazakh
culture can be defined as a Cultural identity traditional ,national
identity and the identity values developed by Kazakh people in
process of cultural-historical development, promoting formation of
Kazakh culture identity on public consciousness. Identity is the
historical process but always the tradition exists in it as a component
of stability, as a component of self that what this identity formed .
Abstract: We integrate TiN/Ni/HfO2/Si RRAM cell with a
vertical gate-all-around (GAA) nanowire transistor to achieve
compact 4F2 footprint in a 1T1R configuration. The tip of the Si
nanowire (source of the transistor) serves as bottom electrode of the
memory cell. Fabricated devices with nanowire diameter ~ 50nm
demonstrate ultra-low current/power switching; unipolar switching
with 10μA/30μW SET and 20μA/30μW RESET and bipolar switching
with 20nA/85nW SET and 0.2nA/0.7nW RESET. Further, the
switching current is found to scale with nanowire diameter making the
architecture promising for future scaling.
Abstract: A hybrid learning automata-genetic algorithm (HLGA) is proposed to solve QoS routing optimization problem of next generation networks. The algorithm complements the advantages of the learning Automato Algorithm(LA) and Genetic Algorithm(GA). It firstly uses the good global search capability of LA to generate initial population needed by GA, then it uses GA to improve the Quality of Service(QoS) and acquiring the optimization tree through new algorithms for crossover and mutation operators which are an NP-Complete problem. In the proposed algorithm, the connectivity matrix of edges is used for genotype representation. Some novel heuristics are also proposed for mutation, crossover, and creation of random individuals. We evaluate the performance and efficiency of the proposed HLGA-based algorithm in comparison with other existing heuristic and GA-based algorithms by the result of simulation. Simulation results demonstrate that this paper proposed algorithm not only has the fast calculating speed and high accuracy but also can improve the efficiency in Next Generation Networks QoS routing. The proposed algorithm has overcome all of the previous algorithms in the literature.
Abstract: The main objective of this paper is to provide an efficient tool for delineating brain tumors in three-dimensional magnetic resonance images. To achieve this goal, we use basically a level-sets approach to delineating three-dimensional brain tumors. Then we introduce a compression plan of 3D brain structures based for the meshes simplification, adapted for time to the specific needs of the telemedicine and to the capacities restricted by network communication. We present here the main stages of our system, and preliminary results which are very encouraging for clinical practice.
Abstract: In the self-stabilizing algorithmic paradigm, each node has a local view of the system, in a finite amount of time the system converges to a global state with desired property. In a graph G =
(V, E), a subset S C V is a 2-packing if Vi c V: IN[i] n SI
Abstract: Background, measuring an individual-s Health
Literacy is gaining attention, yet no appropriate instrument is available
in Taiwan. Measurement tools that were developed and used in
western countries may not be appropriate for use in Taiwan due to a
different language system. Purpose of this research was to develop a
Health Literacy measurement instrument specific for Taiwan adults.
Methods, several experts of clinic physicians; healthcare
administrators and scholars identified 125 common used health related
Chinese phrases from major medical knowledge sources that easy
accessible to the public. A five-point Likert scale is used to measure
the understanding level of the target population. Such measurement is
then used to compare with the correctness of their answers to a health
knowledge test for validation. Samples, samples under study were
purposefully taken from four groups of people in the northern
Pingtung, OPD patients, university students, community residents,
and casual visitors to the central park. A set of health knowledge index
with 10 questions is used to screen those false responses. A sample
size of 686 valid cases out of 776 was then included to construct this
scale. An independent t-test was used to examine each individual
phrase. The phrases with the highest significance are then identified
and retained to compose this scale. Result, a Taiwan Health Literacy
Scale (THLS) was finalized with 66 health-related phrases under nine
divisions. Cronbach-s alpha of each division is at a satisfactory level
of 89% and above. Conclusions, factors significantly differentiate the
levels of health literacy are education, female gender, age, family
members of stroke victims, experience with patient care, and
healthcare professionals in the initial application in this study..
Abstract: The optimal operation of proton exchange membrane fuel cell (PEMFC) requires good water management which is presented under two forms vapor and liquid. Moreover, fuel cells have to reach higher output require integration of some accessories which need electrical power. In order to analyze fuel cells operation and different species transport phenomena a biphasic mathematical model is presented by governing equations set. The numerical solution of these conservation equations is calculated by Matlab program. A multi-criteria optimization with weighting between two opposite objectives is used to determine the compromise solutions between maximum output and minimal stack size. The obtained results are in good agreement with available literature data.
Abstract: Outlier detection in streaming data is very challenging because streaming data cannot be scanned multiple times and also new concepts may keep evolving. Irrelevant attributes can be termed as noisy attributes and such attributes further magnify the challenge of working with data streams. In this paper, we propose an unsupervised outlier detection scheme for streaming data. This scheme is based on clustering as clustering is an unsupervised data mining task and it does not require labeled data, both density based and partitioning clustering are combined for outlier detection. In this scheme partitioning clustering is also used to assign weights to attributes depending upon their respective relevance and weights are adaptive. Weighted attributes are helpful to reduce or remove the effect of noisy attributes. Keeping in view the challenges of streaming data, the proposed scheme is incremental and adaptive to concept evolution. Experimental results on synthetic and real world data sets show that our proposed approach outperforms other existing approach (CORM) in terms of outlier detection rate, false alarm rate, and increasing percentages of outliers.
Abstract: We investigated a modified thermal evaporation
method in the growth process of ZnO nanowires. ZnO nanowires
were fabricated on p-type silicon substrates without using a metal
catalyst. A simple horizontal double-tube system along with
chemical vapor diffusion of the precursor was used to grow the ZnO
nanowires. The substrates were placed in different temperature
zones, and ZnO nanowires with different diameters were obtained for
the different substrate temperatures. In addition to the nanowires,
ZnO microdiscs with different diameters were obtained on another
substrate, which was placed at a lower temperature than the other
substrates. The optical properties and crystalline quality of the ZnO
nanowires and microdiscs were characterized by room temperature
photoluminescence (PL) and Raman spectrometers. The PL and
Raman studies demonstrated that the ZnO nanowires and microdiscs
grown using such set-up had good crystallinity with excellent optical
properties. Rectifying behavior of ZnO/Si heterostructures was
characterized by a simple DC circuit.
Abstract: Scarcity of resources for biodiversity conservation gives rise to the need of strategic investment with priorities given to the cost of conservation. While the literature provides abundant methodological options for biodiversity conservation; estimating true cost of conservation remains abstract and simplistic, without recognising dynamic nature of the cost. Some recent works demonstrate the prominence of economic theory to inform biodiversity decisions, particularly on the costs and benefits of biodiversity however, the integration of the concept of true cost into biodiversity actions and planning are very slow to come by, and specially on a farm level. Conservation planning studies often use area as a proxy for costs neglecting different land values as well as protected areas. These literature consider only heterogeneous benefits while land costs are considered homogenous. Analysis with the assumption of cost homogeneity results in biased estimation; since not only it doesn’t address the true total cost of biodiversity actions and plans, but also it fails to screen out lands that are more (or less) expensive and/or difficult (or more suitable) for biodiversity conservation purposes, hindering validity and comparability of the results. Economies of scope” is one of the other most neglected aspects in conservation literature. The concept of economies of scope introduces the existence of cost complementarities within a multiple output production system and it suggests a lower cost during the concurrent production of multiple outputs by a given farm. If there are, indeed, economies of scope then simplistic representation of costs will tend to overestimate the true cost of conservation leading to suboptimal outcomes. The aim of this paper, therefore, is to provide first road review of the various theoretical ways in which economies of scope are likely to occur of how they might occur in conservation. Consequently, the paper addresses gaps that have to be filled in future analysis.
Abstract: Oil debris signal generated from the inductive oil
debris monitor (ODM) is useful information for machine condition
monitoring but is often spoiled by background noise. To improve the
reliability in machine condition monitoring, the high-fidelity signal
has to be recovered from the noisy raw data. Considering that the noise
components with large amplitude often have higher frequency than
that of the oil debris signal, the integral transform is proposed to
enhance the detectability of the oil debris signal. To cancel out the
baseline wander resulting from the integral transform, the empirical
mode decomposition (EMD) method is employed to identify the trend
components. An optimal reconstruction strategy including both
de-trending and de-noising is presented to detect the oil debris signal
with less distortion. The proposed approach is applied to detect the oil
debris signal in the raw data collected from an experimental setup. The
result demonstrates that this approach is able to detect the weak oil
debris signal with acceptable distortion from noisy raw data.
Abstract: This paper explores the features of political economy in the dynamics of representative politics in India. Politics is seen as enhancing economic benefits through acquiring and maintenance of power in the realm of democratic set up. The system of representation is riddled with competitive populism. Emerging leaders and parties are forced to accommodate their ideologies in coping with competitive politics. Electoral politics and voting behaviour reflect series of influences mooted by the politicians. Voters are accustomed to expect benefits outs of state exchequer. The electoral competitors show a changing phase of investment and return policy. Every elector has to spend and realize his costs in his tenure. In the case of defeated electors, even the cost recovery is not possible directly; there are indirect means to recover their costs. The series of case studies show the method of party funding, campaign financing, electoral expenditure, and cost recovery. Regulations could not restrict the level of spending. Several cases of disproportionate accumulation of wealth by the politicians reveal that money played a major part in electoral process. The political economy of representative politics hitherto ignores how a politician spends and recovers his cost and multiples his wealth. To be sure, the acquiring and maintenance of power is to enhance the wealth of the electors.
Abstract: An ontology is a data model that represents a set of
concepts in a given field and the relationships among those concepts.
As the emphasis on achieving a semantic web continues to escalate,
ontologies for all types of domains increasingly will be developed.
These ontologies may become large and complex, and as their size
and complexity grows, so will the need for multi-user interfaces for
ontology curation. Herein a functionally comprehensive, generic
approach to maintaining an ontology as a relational database is
presented. Unlike many other ontology editors that utilize a database,
this approach is entirely domain-generic and fully supports Webbased,
collaborative editing including the designation of different
levels of authorization for users.
Abstract: Tailor-welded Blanks (TWBs) are tailor made for
different complex component designs by welding multiple metal
sheets with different thicknesses, shapes, coatings or strengths prior
to forming. In this study the Hemispherical Die Stretching (HDS) test
(out-of-plane stretching) of TWBs were simulated via
ABAQUS/Explicit to obtain the Forming Limit Diagrams (FLDs) of
Stainless steel (AISI 304) laser welded blanks with different
thicknesses. Two criteria were used to detect the start of necking to
determine the FLD for TWBs and parent sheet metals. These two
criteria are the second derivatives of the major and thickness strains
that are given from the strain history of simulation. In the other word,
in these criteria necking starts when the second derivative of
thickness or major strain reaches its maximum. With having the time
of onset necking, one can measure the major and minor strains at the
critical area and determine the forming limit curve.
Abstract: In this paper, a near lossless image coding scheme
based on Orthogonal Polynomials Transform (OPT) has been
presented. The polynomial operators and polynomials basis operators
are obtained from set of orthogonal polynomials functions for the
proposed transform coding. The image is partitioned into a number of
distinct square blocks and the proposed transform coding is applied to
each of these individually. After applying the proposed transform
coding, the transformed coefficients are rearranged into a sub-band
structure. The Embedded Zerotree (EZ) coding algorithm is then
employed to quantize the coefficients. The proposed transform is
implemented for various block sizes and the performance is
compared with existing Discrete Cosine Transform (DCT) transform
coding scheme.
Abstract: The operating control parameters of injection
flushing type of electrical discharge machining process on stainless
steel 304 workpiece with copper tools are being optimized
according to its individual machining characteristic i.e. material
removal rate (MRR). Lower MRR during EDM machining process
may decrease its- machining productivity. Hence, the quality
characteristic for MRR is set to higher-the-better to achieve the
optimum machining productivity. Taguchi method has been used
for the construction, layout and analysis of the experiment for each
of the machining characteristic for the MRR. The use of Taguchi
method in the experiment saves a lot of time and cost of preparing
and machining the experiment samples. Therefore, an L18
Orthogonal array which was the fundamental component in the
statistical design of experiments has been used to plan the
experiments and Analysis of Variance (ANOVA) is used to
determine the optimum machining parameters for this machining
characteristic. The control parameters selected for this
optimization experiments are polarity, pulse on duration, discharge
current, discharge voltage, machining depth, machining diameter
and dielectric liquid pressure. The result had shown that the higher
the discharge voltage, the higher will be the MRR.