Abstract: Type 2 diabetes mellitus (T2DM) is a complex
metabolic disorder that characterized by the presence of high glucose
in blood that cause from insulin resistance and insufficiency due to
deterioration β-cell Langerhans functions. T2DM is commonly
caused by the combination of inherited genetic variations as well as
our own lifestyle. Metallothionein (MT) is a known cysteine-rich
protein responsible in helping zinc homeostasis which is important in
insulin signaling and secretion as well as protection our body from
reactive oxygen species (ROS). MT scavenged ROS and free
radicals in our body happen to be one of the reasons of T2DM and its
complications. The objective of this study was to investigate the
association of MT1A and MT2A polymorphisms between T2DM and
control subjects among Malay populations. This study involved 150
T2DM and 120 Healthy individuals of Malay ethnic with mixed
genders. The genomic DNA was extracted from buccal cells and
amplified for MT1A and MT2A loci; the 347bp and 238bp banding
patterns were respectively produced by mean of the Polymerase
Chain Reaction (PCR). The PCR products were digested with Mlucl
and Tsp451 restriction enzymes respectively and producing
fragments lengths of (158/189/347bp) and (103/135/238bp)
respectively. The ANOVA test was conducted and it shown that there
was a significant difference between diabetic and control subjects for
age, BMI, WHR, SBP, FPG, HBA1C, LDL, TG, TC and family
history with (P0.05). The genotype
frequency for AA, AG and GG of MT1A polymorphisms was 72.7%,
22.7% and 4.7% in cases and 15%, 55% and 30% in control
respectively. As for MT2A, genotype frequency of GG, GC and CC
was 42.7%, 27.3% and 30% in case and 5%, 40% and 55% for
control respectively. Both polymorphisms show significant difference
between two investigated groups with (P=0.000). The Post hoc test
was conducted and shows a significant difference between the
genotypes within each polymorphism (P=0. 000). The MT1A and
MT2A polymorphisms were believed to be the reliable molecular
markers to distinguish the T2DM subjects from healthy individuals in
Malay populations.
Abstract: As emails communications have no consistent
authentication procedure to ensure the authenticity, we present an
investigation analysis approach for detecting forged emails based on
Random Forests and Naïve Bays classifiers. Instead of investigating
the email headers, we use the body content to extract a unique writing
style for all the possible suspects. Our approach consists of four main
steps: (1) The cybercrime investigator extract different effective
features including structural, lexical, linguistic, and syntactic
evidence from previous emails for all the possible suspects, (2) The
extracted features vectors are normalized to increase the accuracy
rate. (3) The normalized features are then used to train the learning
engine, (4) upon receiving the anonymous email (M); we apply the
feature extraction process to produce a feature vector. Finally, using
the machine learning classifiers the email is assigned to one of the
suspects- whose writing style closely matches M. Experimental
results on real data sets show the improved performance of the
proposed method and the ability of identifying the authors with a
very limited number of features.
Abstract: This paper describes a novel monitoring scheme to
minimize total active power in digital circuits depend on the demand
frequency, by adjusting automatically both supply voltage and
threshold voltages based on circuit operating conditions such as
temperature, process variations, and desirable frequency. The delay
monitoring results, will be control and apply so as to be maintained at
the minimum value at which the chip is able to operate for a given
clock frequency. Design details of power monitor are examined using
simulation framework in 32nm BTPM model CMOS process.
Experimental results show the overhead of proposed circuit in terms
of its power consumption is about 40 μW for 32nm technology;
moreover the results show that our proposed circuit design is not far
sensitive to the temperature variations and also process variations.
Besides, uses the simple blocks which offer good sensitivity, high
speed, the continuously feedback loop. This design provides up to
40% reduction in power consumption in active mode.
Abstract: Dengue, a disease found in most tropical and
subtropical areas of the world. It has become the most common
arboviral disease of humans. This disease is caused by any of four
serotypes of dengue virus (DEN1-DEN4). In many endemic
countries, the average age of getting dengue infection is shifting
upwards, dengue in pregnancy and infancy are likely to be
encountered more frequently. The dynamics of the disease is studied
by a compartmental model involving ordinary differential equations
for the pregnant, infant human and the vector populations. The
stability of each equilibrium point is given. The epidemic dynamic is
discussed. Moreover, the numerical results are shown for difference
values of dengue antibody.
Abstract: This paper presents a CFD analysis of the flow field
around a thin flat plate of infinite span inclined at 90° to a fluid
stream of infinite extent. Numerical predictions have been compared
to experimental measurements, in order to assess the potential of the
finite volume code of determining the aerodynamic forces acting on a
bluff body invested by a fluid stream of infinite extent.
Several turbulence models and spatial node distributions have
been tested. Flow field characteristics in the neighborhood of the flat
plate have been investigated, allowing the development of a
preliminary procedure to be used as guidance in selecting the
appropriate grid configuration and the corresponding turbulence
model for the prediction of the flow field over a two-dimensional
vertical flat plate.
Abstract: Almost all Libyan industries (both private and public) have struggled with many difficulties during the past three decades due to many problems. These problems have created a strongly negative impact on the productivity and utilization of many companies within Libya. This paper studies the current awareness and implementation levels of Just-In-Time (JIT) within the Libyan Textile private industry. A survey has been applied in this study using an intensive detailed questionnaire. Based on the analysis of the survey responses, the results show that the management body within the surveyed companies has a modest strategy towards most of the areas that are considered as being very crucial in any successful implementation of JIT. The results also show a variation within the implementation levels of the JIT elements as these varies between Low and Acceptable levels. The paper has also identified limitations within the investigated areas within this industry, and has pointed to areas where senior managers within the Libyan textile industry should take immediate actions in order to achieve effective implementation of JIT within their companies.
Abstract: Failure in mastery of motor skills proficiency during
childhood has been seen as a detrimental factor for children to be
physically active. Lack of motor skills proficiency tends to reduce
children’s competency and confidence level to participate in physical
activity. As a consequence of less participation in physical activity,
children will turn to be overweight and obese. It has been suggested
that children who master motor skill proficiency will be more
involved in physical activity thus preventing them from being
overweight. Obesity has become a serious childhood health issues
worldwide. Previous studies have found that children who were
overweight and obese were generally less active however these
studies focused on one gender. This study aims to compare motor
skill proficiency of underweight, normal-weight, overweight and
obese young boys as well as to determine the relationship between
motor skills proficiency and body composition. 112 boys aged
between 8 to 10 years old participated in this study. Participants were
assigned to four groups; underweight, normal-weight, overweight and
obese using BMI-age percentile chart for children. Bruininks-
Oseretsky Test Second Edition-Short Form was administered to
assess their motor skill proficiency. Meanwhile, body composition
was determined by the skinfold thickness measurement. Result
indicated that underweight and normal children were superior in
motor skills proficiency compared to overweight and obese children
(p < 0.05). A significant strong inverse correlation between motor
skills proficiency and body composition (r = -0.849) is noted. The
findings of this study could be explained by non-contributory mass
that carried by overweight and obese children leads to biomechanical
movement inefficiency which will become detrimental to motor skills
proficiency. It can be concluded that motor skills proficiency is
inversely correlated with body composition.
Abstract: Application of wood in rural construction is diffused
all around the world since remote times. However, its inclusion in
structural design deserves strong support from broad knowledge of
material properties. The pertinent literature reveals the application of
optical methods in determining the complete field displacement on
bodies exhibiting regular as well as irregular surfaces. The use of
moiré techniques in experimental mechanics consists in analyzing the
patterns generated on the body surface before and after deformation.
The objective of this research work is to study the qualitative
deformation behavior of wooden testing specimens under specific
loading situations. The experiment setup follows the literature
description of shadow moiré methods. Results indicate strong
anisotropy influence of the generated displacement field. Important
qualitative as well as quantitative stress and strain distribution were
obtained wooden members which are applicable to rural
constructions.
Abstract: A full six degrees of freedom (6-DOF) flight dynamics
model is proposed for the accurate prediction of short and long-range
trajectories of high spin and fin-stabilized projectiles via atmospheric
flight to final impact point. The projectiles is assumed to be both rigid
(non-flexible), and rotationally symmetric about its spin axis launched
at low and high pitch angles. The mathematical model is based on the
full equations of motion set up in the no-roll body reference frame and
is integrated numerically from given initial conditions at the firing
site. The projectiles maneuvering motion depends on the most
significant force and moment variations, in addition to wind and
gravity. The computational flight analysis takes into consideration the
Mach number and total angle of attack effects by means of the
variable aerodynamic coefficients. For the purposes of the present
work, linear interpolation has been applied from the tabulated database
of McCoy-s book. The developed computational method gives
satisfactory agreement with published data of verified experiments and
computational codes on atmospheric projectile trajectory analysis for
various initial firing flight conditions.
Abstract: Temperature dependence of force of gravitation is one
of the fundamental problems of physics. This problem has got special
value in connection with that the general theory of relativity,
supposing the weakest positive influence of a body temperature on its
weight, actually rejects an opportunity of measurement of negative
influence of temperature on gravity in laboratory conditions. Really,
the recognition of negative temperature dependence of gravitation,
for example, means basic impossibility of achievement of a
singularity («a black hole») at a gravitational collapse. Laboratory
experiments with exact weighing the heated up metal samples,
indicating negative influence temperatures of bodies on their physical
weight are described. Influence of mistakes of measurements is
analyzed. Calculations of distribution of temperature in volume of the
bar, agreed with experimental data of time dependence of weight of
samples are executed. The physical substantiation of negative
temperature dependence of weight of the bodies, based on correlation
of acceleration at thermal movement of micro-particles of a body and
its absolute temperature, are given.
Abstract: Stick models are widely used in studying the
behaviour of straight as well as skew bridges and viaducts subjected
to earthquakes while carrying out preliminary studies. The
application of such models to highly curved bridges continues to
pose challenging problems. A viaduct proposed in the foothills of the
Himalayas in Northern India is chosen for the study. It is having 8
simply supported spans @ 30 m c/c. It is doubly curved in horizontal
plane with 20 m radius. It is inclined in vertical plane as well. The
superstructure consists of a box section. Three models have been
used: a conventional stick model, an improved stick model and a 3D
finite element model. The improved stick model is employed by
making use of body constraints in order to study its capabilities. The
first 8 frequencies are about 9.71% away in the latter two models.
Later the difference increases to 80% in 50th mode. The viaduct was
subjected to all three components of the El Centro earthquake of May
1940. The numerical integration was carried out using the Hilber-
Hughes-Taylor method as implemented in SAP2000. Axial forces
and moments in the bridge piers as well as lateral displacements at
the bearing levels are compared for the three models. The maximum
difference in the axial forces and bending moments and
displacements vary by 25% between the improved and finite element
model. Whereas, the maximum difference in the axial forces,
moments, and displacements in various sections vary by 35%
between the improved stick model and equivalent straight stick
model. The difference for torsional moment was as high as 75%. It is
concluded that the stick model with body constraints to model the
bearings and expansion joints is not desirable in very sharp S curved
viaducts even for preliminary analysis. This model can be used only
to determine first 10 frequency and mode shapes but not for member
forces. A 3D finite element analysis must be carried out for
meaningful results.
Abstract: Commercial hydroxyapatite (HA) was reinforced by
adding 2, 5, and 10 wt % of 28.5%CaO-28.5%P2O5-38%Na2 O-
5%CaF2 based glass and then sintered. Although HA shows good
biocompatibility with the human body, its applications are limited to
non load-bearing areas and coatings due to its poor mechanical
properties. These mechanical properties can be improved
substantially with addition of glass ceramics by sintering. In this
study, the effects of sintering hydroxyapatite with above specified
phosphate glass additions are quantified. Each composition was
sintered over a range of temperatures. Scanning electron microscopy
and x-ray diffraction were used to characterize the microstructure and
phases of the composites. The density, microhardness, and
compressive strength were measured using Archimedes Principle,
Vickers Microhardness Tester (at 0.98 N), and Instron Universal
Testing Machine (cross speed of 0.5 mm/min) respectively. These
results were used to indicate which composition provided suitable
material for use in hard tissue replacement. Composites containing 10
wt % glass additions formed dense HA/TCP (tricalcium phosphate)
composite materials possessing good compressive strength and
hardness than HA. In-vitro bioactivity was assessed by evaluating
changes in pH and Ca2+ ion concentration of SBF-simulated body
fluid on immersion of these composites in it for two weeks.
Abstract: Recent advancements in sensor technologies and
Wireless Body Area Networks (WBANs) have led to the
development of cost-effective healthcare devices which can be used
to monitor and analyse a person-s physiological parameters from
remote locations. These advancements provides a unique opportunity
to overcome current healthcare challenges of low quality service
provisioning, lack of easy accessibility to service varieties, high costs
of services and increasing population of the elderly experienced
globally. This paper reports on a prototype implementation of an
architecture that seamlessly integrates Wireless Body Area Network
(WBAN) with Web services (WS) to proactively collect
physiological data of remote patients to recommend diagnostic
services. Technologies based upon WBAN and WS can provide
ubiquitous accessibility to a variety of services by allowing
distributed healthcare resources to be massively reused to provide
cost-effective services without individuals physically moving to the
locations of those resources. In addition, these technologies can
reduce costs of healthcare services by allowing individuals to access
services to support their healthcare. The prototype uses WBAN body
sensors implemented on arduino fio platforms to be worn by the
patient and an android smart phone as a personal server. The
physiological data are collected and uploaded through GPRS/internet
to the Medical Health Server (MHS) to be analysed. The prototype
monitors the activities, location and physiological parameters such as
SpO2 and Heart Rate of the elderly and patients in rehabilitation.
Medical practitioners would have real time access to the uploaded
information through a web application.
Abstract: In the present article, effect of non-uniform excitation
of reservoir bottom on nonlinear response of concrete gravity dams is
considered. Anisotropic damage mechanics approach is used to model nonlinear behavior of mass concrete in 2D space. The tallest
monolith of Pine Flat dam is selected as a case study. The horizontal
and vertical components of 1967 Koyna earthquake is used to excite
the system. It is found that crest response and stresses within the dam body decrease significantly when the reservoir is excited nonuniformly. In addition, the crack profiles within the dam body and in vicinity of the neck decreases.
Abstract: Feeder is one of the airships of the Multibody Advanced Airship for Transport (MAAT) system, under development within the EU FP7 project. MAAT is based on a modular concept composed of two different parts that have the possibility to join; respectively they are the so-called Cruiser and Feeder, designed on the lighter than air principle. Feeder, also named ATEN (Airship Transport Elevator Network), is the smaller one which joins the bigger one, Cruiser, also named PTAH (Photovoltaic modular Transport Airship for High altitude),envisaged to happen at 15km altitude. During the MAAT design phase, the aerodynamic studies of the both airships and their interactions are analyzed. The objective of these studies is to understand the aerodynamic behavior of all the preselected configurations, as an important element in the overall MAAT system design. The most of these configurations are only simulated by CFD, while the most feasible one is experimentally analyzed in order to validate and thrust the CFD predictions. This paper presents the numerical and experimental investigation of the Feeder “conical like" shape configuration. The experiments are focused on the aerodynamic force coefficients and the pressure distribution over the Feeder outer surface, while the numerical simulation cover also the analysis of the velocity and pressure distribution. Finally, the wind tunnel experiment is compared with its CFD model in order to validate such specific simulations with respective experiments and to better understand the difference between the wind tunnel and in-flight circumstances.
Abstract: The purpose of this study was to analyze relationship
between gender, BMI, and lifestyle with bone mineral density
(BMD) of adolescent in urban areas . The place of this study in
Jakarta State University, Indonesia. The number of samples involved
as many as 200 people, consisting of 100 men and 100 women. BMD
was measured using Quantitative Ultrasound Bone Densitometry.
While the questionnaire used to collect data on age, gender, and
lifestyle (calcium intake, smoking habits, alcohol consumption, tea,
coffee, sports, and sun exposure). Mean age of men and women,
respectively as much as 20.7 ± 2.18 years and 21 ± 1.61 years. Mean
BMD values of men was 1.084 g/cm ² ± 0.11 while women was
0.976 g/cm ² ± 0.10. Men and women with normal BMD respectively
as much as 46.7% and 16.7%. Men and women affected by
osteopenia respectively as much as 50% and 80%. Men and women
affected by osteoporosis respectively as much as 3.3% and 3.3%.
Mean BMI of men and women, respectively as much as 21.4 ± 2.07
kg/m2 and 20.9 ± 2.06 kg/m2. Mean lifestyle score of men and
women , respectively as much as 71.9 ± 5.84 and 70.1 ± 5.67
(maximum score 100). Based on Spearman and Pearson Correlation
test, there were relationship significantly between gender and
lifestyle with BMD.
Abstract: In the present study, 49 Hybrid (Catla catla ♂ x
Labeo rohita ♀) were sampled from Al-Raheem Fish Hatchery,
Village Ali Pure Shamali, Jhang Road, 18 Km from Muzaffar Garh
using a cast net and Live fishes were transported to research
laboratory. Mean percentage for water found 79.13 %, ash 6.58 %, fat
2.22 % and protein content 12.06 % in whole wet body weight. It was
observed that body constituents were found increasing in the same
proportion with an increase in body weight while significant
proportional increase was observed with total length. However,
condition factor remained insignificant (P>0.05) with body
constituents.
Abstract: Obesity is frequent attendant phenomenon of patients
with endocrinological disease. Between BMI and endocrinological
diseases is close correlation. In thesis we focused on the allocation of
hormone concentration – PTH and TSH, CHOL a mineral element Ca
in a blood serum. The examined group was formed by 100
respondents (women) aged 36 – 83 years, who were divided into two
groups – control group (CG), group with diagnosed endocrine disease
(DED). The concentration of PTH and TSH, Ca and CHOL was
measured through the medium of analyzers Cobas e411 (Japan);
Cobas Integra 400 (Switzerland). At individuals was measured body
weight as well as stature and thereupon from those data we
enumerated BMI. On the basis of Student T-test in biochemical
parameter of PTH and Ca we found out significantly meaningful
difference (p
Abstract: A two dimensional three segments coupled pendulum system that mathematically models human arm configuration was developed along with constructing and solving the equations of motions for this model using the energy (work) based approach of Lagrange. The equations of motion of the model were solved iteratively both as an initial value problem and as a two point boundary value problem. In the initial value problem solutions, both the initial system configuration (segment angles) and initial system velocity (segment angular velocities) were used as inputs, whereas, in the two point boundary value problem solutions initial and final configurations and time were used as inputs to solve for the trajectory of motion. The results suggest that the model solutions are sensitive to small changes in the dynamic forces applied to the system as well as to the initial and boundary conditions used. To overcome the system sensitivity a new approach is suggested.
Abstract: In switch mode power inverters, small sized inverters
can be obtained by increasing the switching frequency. Switching
frequency increment causes high driver losses. Also, high dt
di
and
dt
dv
produced by the switching action creates high Electromagnetic
Interference (EMI) and Radio Frequency Interference (RFI). In this
paper, a series half bridge series resonant inverter circuit is simulated
and evaluated practically to demonstrate the turn-on and turn-off
conditions during zero or close to zero voltage switching. Also, the
reverse recovery current effects of the body diode of the MOSFETs
were investigated by operating above and below resonant frequency.