Association of Selected Biochemical Markers and Body Mass Index in Women with Endocrine Disorders
Obesity is frequent attendant phenomenon of patients
with endocrinological disease. Between BMI and endocrinological
diseases is close correlation. In thesis we focused on the allocation of
hormone concentration – PTH and TSH, CHOL a mineral element Ca
in a blood serum. The examined group was formed by 100
respondents (women) aged 36 – 83 years, who were divided into two
groups – control group (CG), group with diagnosed endocrine disease
(DED). The concentration of PTH and TSH, Ca and CHOL was
measured through the medium of analyzers Cobas e411 (Japan);
Cobas Integra 400 (Switzerland). At individuals was measured body
weight as well as stature and thereupon from those data we
enumerated BMI. On the basis of Student T-test in biochemical
parameter of PTH and Ca we found out significantly meaningful
difference (p<0,05) between CG and DED. In CG we made a
founding the association between BMI and PTH by means of
correlation analysis.
[1] J. Čáp, "Onemocnení hypotalamu a neurohypofýzy,” Postgraduální
medicína, vol. 15, no. 7, pp. 701, July 2013.
[2] M. J. Bolland, A. B. Grey, G. D. Gamble, I. R. Reid, "Association
between primary hyperparathyroidism and increased body weight: a
metaanalysis," J Clin Endocrinol Metab., vol. 90, no. 3, pp. 1525–1530,
March 2005.
[3] V. Zamrazil, "Nemoci štítne žlázy v klinické praxi,” Postgraduální
medicína, vol. 15, no. 7, pp. 720 – 729, July 2013.
[4] G. Boden, G. I. Shulman, "Free fatty acids in obesity and type 2 diabetes:
defining their role in the development of insulin resistance and beta-cell
dysfunction,” Eur J Clin Invest., vol. 32, no. 3, pp. 14 – 23, March 2002.
[5] T. Zima, A. Kazda, R. Průša, P. Štern, M. Aschermann, M. Babjuk et al.,
"Laboratórni diagnostika” 3. vyd. Praha: Galén, 2013, p. 906, ISBN
978-80-7492-062-2.
[6] Ch. Dreschler, D. C. Grootendorst, E. W. Boeschten, R. T.
Krediet, Ch. Wanner, F. W. Dekker, "Changes in parathyroid
hormone and body mass index and association with mortality in
dialysis patients,” Nephrol Dial Transplant., vol. 19, no. 26, pp.
1340 – 1346, Sept. 2011.
[7] A. Dukát, "Metabolický syndróm predstavuje dnes jeden z
najdôležitejších problémov súčasnej medicíny,” Súč klin pr., vol. 3, p. 2-
4, Sept. 2004.
[8] M. Roden, „Metabolic syndrom: a new epidemic? How to manage
diabetes and cardiovascular diseases," 3rd International Meeting on
Outcomes in Diabetes, Istanbul, Turkey. 15-16 November 2007.
[9] J. Jurkovičová, Ľ. Ághová, Z. Štefániková, "Perception of risk in
relation to prevalence of cardiovascular disease risk factor in selected
population group,” Homeostasis, vol. 40, no. 3 – 4, p. 139 – 141, April
2000.
[10] D. Dobrota, et al., "Lekárska biochémia,”. 1. vyd. Martin: Osveta, 2012,
p. 723, ISBN 978-80-8063-293-9.
[11] E. Kamycheva, J. Sundsfjord, R. Jorde, „Serum parathyroid
hormone level is associated with body mass index,” Eur J
Endocrinol., vol. 151, no. 2, pp. 167 – 172, Feb. 2004.
[12] C. P. Kovesdy, S. Ahmadzadeh, J. E. Anderson, K. Kalantar-Zadeh,
"Obesity is associated with secondary hyperparathyroidism,” Clin J Am
Soc Nephrol., vol. 5 no. 2, p. 1024-1029, Sept. 2007.
[13] A. Solanki, S. Bansal, S. Jidal, V. Saxena, U. S. Shukla, "Relationship
of serum thyroid stimulating hormone with body mass index in
healthy adults,” Indian J Endocrinol Metab., vol. 17, no. 7, pp. 167 –
169, Oct 2013.
[14] C. M. Kitahara, E. A. Platz, P. W. Ladenson, A. M. Mondul, A.
Menke, A. B. González, ”Body Fatness and Markers of thyroid
function among U.S. men and women,” Plos One, vol. 7, no. 4, pp.
1 – 6, April 2012.
[15] L. Mehran, A. Amouzegar, H. Deshad, F. Azizi, "Association between
serum TSH concentration and body mass index in euthyroid
subject,” Arch Iran Med., vol. 15, no. 7, pp. 400-403, July 2012.
[16] A. Milionis, Ch. Milionis, "Correlation between body mass index
and thyroid function in euthyroid individuals in Greece.” Online.
Available: http://dx.doi.org/10.1155/2013/651494, May2014.
[1] J. Čáp, "Onemocnení hypotalamu a neurohypofýzy,” Postgraduální
medicína, vol. 15, no. 7, pp. 701, July 2013.
[2] M. J. Bolland, A. B. Grey, G. D. Gamble, I. R. Reid, "Association
between primary hyperparathyroidism and increased body weight: a
metaanalysis," J Clin Endocrinol Metab., vol. 90, no. 3, pp. 1525–1530,
March 2005.
[3] V. Zamrazil, "Nemoci štítne žlázy v klinické praxi,” Postgraduální
medicína, vol. 15, no. 7, pp. 720 – 729, July 2013.
[4] G. Boden, G. I. Shulman, "Free fatty acids in obesity and type 2 diabetes:
defining their role in the development of insulin resistance and beta-cell
dysfunction,” Eur J Clin Invest., vol. 32, no. 3, pp. 14 – 23, March 2002.
[5] T. Zima, A. Kazda, R. Průša, P. Štern, M. Aschermann, M. Babjuk et al.,
"Laboratórni diagnostika” 3. vyd. Praha: Galén, 2013, p. 906, ISBN
978-80-7492-062-2.
[6] Ch. Dreschler, D. C. Grootendorst, E. W. Boeschten, R. T.
Krediet, Ch. Wanner, F. W. Dekker, "Changes in parathyroid
hormone and body mass index and association with mortality in
dialysis patients,” Nephrol Dial Transplant., vol. 19, no. 26, pp.
1340 – 1346, Sept. 2011.
[7] A. Dukát, "Metabolický syndróm predstavuje dnes jeden z
najdôležitejších problémov súčasnej medicíny,” Súč klin pr., vol. 3, p. 2-
4, Sept. 2004.
[8] M. Roden, „Metabolic syndrom: a new epidemic? How to manage
diabetes and cardiovascular diseases," 3rd International Meeting on
Outcomes in Diabetes, Istanbul, Turkey. 15-16 November 2007.
[9] J. Jurkovičová, Ľ. Ághová, Z. Štefániková, "Perception of risk in
relation to prevalence of cardiovascular disease risk factor in selected
population group,” Homeostasis, vol. 40, no. 3 – 4, p. 139 – 141, April
2000.
[10] D. Dobrota, et al., "Lekárska biochémia,”. 1. vyd. Martin: Osveta, 2012,
p. 723, ISBN 978-80-8063-293-9.
[11] E. Kamycheva, J. Sundsfjord, R. Jorde, „Serum parathyroid
hormone level is associated with body mass index,” Eur J
Endocrinol., vol. 151, no. 2, pp. 167 – 172, Feb. 2004.
[12] C. P. Kovesdy, S. Ahmadzadeh, J. E. Anderson, K. Kalantar-Zadeh,
"Obesity is associated with secondary hyperparathyroidism,” Clin J Am
Soc Nephrol., vol. 5 no. 2, p. 1024-1029, Sept. 2007.
[13] A. Solanki, S. Bansal, S. Jidal, V. Saxena, U. S. Shukla, "Relationship
of serum thyroid stimulating hormone with body mass index in
healthy adults,” Indian J Endocrinol Metab., vol. 17, no. 7, pp. 167 –
169, Oct 2013.
[14] C. M. Kitahara, E. A. Platz, P. W. Ladenson, A. M. Mondul, A.
Menke, A. B. González, ”Body Fatness and Markers of thyroid
function among U.S. men and women,” Plos One, vol. 7, no. 4, pp.
1 – 6, April 2012.
[15] L. Mehran, A. Amouzegar, H. Deshad, F. Azizi, "Association between
serum TSH concentration and body mass index in euthyroid
subject,” Arch Iran Med., vol. 15, no. 7, pp. 400-403, July 2012.
[16] A. Milionis, Ch. Milionis, "Correlation between body mass index
and thyroid function in euthyroid individuals in Greece.” Online.
Available: http://dx.doi.org/10.1155/2013/651494, May2014.
@article{"International Journal of Medical, Medicine and Health Sciences:51468", author = "M. Mydlárová Blaščáková and J. Bernasovská and J. Poráčová and I. Boroňová", title = "Association of Selected Biochemical Markers and Body Mass Index in Women with Endocrine Disorders", abstract = "Obesity is frequent attendant phenomenon of patients
with endocrinological disease. Between BMI and endocrinological
diseases is close correlation. In thesis we focused on the allocation of
hormone concentration – PTH and TSH, CHOL a mineral element Ca
in a blood serum. The examined group was formed by 100
respondents (women) aged 36 – 83 years, who were divided into two
groups – control group (CG), group with diagnosed endocrine disease
(DED). The concentration of PTH and TSH, Ca and CHOL was
measured through the medium of analyzers Cobas e411 (Japan);
Cobas Integra 400 (Switzerland). At individuals was measured body
weight as well as stature and thereupon from those data we
enumerated BMI. On the basis of Student T-test in biochemical
parameter of PTH and Ca we found out significantly meaningful
difference (p", keywords = "Biochemical markers, hormones, obesity, women.", volume = "8", number = "9", pages = "535-4", }
