Abstract: It has been established that microRNAs (miRNAs) play
an important role in gene expression by post-transcriptional regulation
of messengerRNAs (mRNAs). However, the precise relationships
between microRNAs and their target genes in sense of numbers,
types and biological relevance remain largely unclear. Dissecting the
miRNA-target relationships will render more insights for miRNA
targets identification and validation therefore promote the understanding
of miRNA function. In miRBase, miRanda is the key
algorithm used for target prediction for Zebrafish. This algorithm
is high-throughput but brings lots of false positives (noise). Since
validation of a large scale of targets through laboratory experiments
is very time consuming, several computational methods for miRNA
targets validation should be developed. In this paper, we present an
integrative method to investigate several aspects of the relationships
between miRNAs and their targets with the final purpose of extracting
high confident targets from miRanda predicted targets pool. This is
achieved by using the techniques ranging from statistical tests to
clustering and association rules. Our research focuses on Zebrafish.
It was found that validated targets do not necessarily associate with
the highest sequence matching. Besides, for some miRNA families,
the frequency of their predicted targets is significantly higher in the
genomic region nearby their own physical location. Finally, in a case
study of dre-miR-10 and dre-miR-196, it was found that the predicted
target genes hoxd13a, hoxd11a, hoxd10a and hoxc4a of dre-miR-
10 while hoxa9a, hoxc8a and hoxa13a of dre-miR-196 have similar
characteristics as validated target genes and therefore represent high
confidence target candidates.
Abstract: This paper presents a new sufficient condition for the
existence, uniqueness and global asymptotic stability of the equilibrium point for Cohen-Grossberg neural networks with multiple time delays. The results establish a relationship between the network parameters
of the neural system independently of the delay parameters. The results are also compared with the previously reported results in
the literature.
Abstract: The objective of this research was to find the
relationship between auspicious meaning in eastern wisdom and the
interpretation as a guideline for the design and development of
community souvenirs. The sample group included 400 customers in
Bangkok who used to buy community souvenir products. The
information was applied to design the souvenirs which were
considered for the appropriateness by 5 design specialists. The data
were analyzed to find frequency, percentage, and SD with the results
as follows. 1) The best factor referring to the auspicious meaning is
color. The application of auspicious meaning can make the value
added to the product and bring the fortune to the receivers. 2) The
effectiveness of the auspicious meaning integration on the design of
community souvenir product was in high level. When considering in
each aspect, it was found that the interpretation aspect was in high
level, the congruency of the auspicious meaning and the utility of the
product was in high level. The attractiveness and the good design
were in very high level while the potential of the value added in the
product design was in high level. The suitable application to the
design of community souvenir product was in high level.
Abstract: The mountain road slope failures triggered by
earthquake activities and torrential rain namely to create the disaster.
Province Road No. 24 is a main route to the Wutai Township. The area
of the study is located at the mileages between 46K and 47K along the
road. However, the road has been suffered frequent damages as a result
of landslide and slope failures during typhoon seasons. An
understanding of the sliding behaviors in the area appears to be
necessary. Slope failures triggered by earthquake activities and heavy
rainfalls occur frequently. The study is to understand the mechanism
of slope failures and to look for the way to deal with the situation. In
order to achieve these objectives, this paper is based on theoretical and
structural geology data interpretation program to assess the potential
slope sliding behavior. The study showed an intimate relationship
between the landslide behavior of the slopes and the stratum materials,
based on structural geology analysis method to analysis slope stability
and finds the slope safety coefficient to predict the sites of destroyed
layer. According to the case study and parameter analyses results, the
slope mainly slips direction compared to the site located in the
southeast area. Find rainfall to result in the rise of groundwater level is
main reason of the landslide mechanism. Future need to set up
effective horizontal drain at corrective location, that can effective
restrain mountain road slope failures and increase stability of slope.
Abstract: The evolution in project management was triggered by
the changes in management philosophy and practices in order to
maintain competitive advantage and continuous success in the field.
The purpose of this paper is to highlight the practicality of cognitive
style and unlearning approach in influencing the achievement of
project success by project managers. It introduces the concept of
planning, knowing and creating style from cognitive style field in the
light of achieving time, cost, quality and stakeholders appreciation in
project success context. Further it takes up a discussion of the
unlearning approach as a moderator in enhancing the relationship
between cognitive style and project success. The paper bases itself on
literature review from established disciplines like psychology,
sociology and philosophy regarding cognitive style, unlearning and
project success in general. The analysis and synthesis of literature in
the subject area a conceptual paper is utilized as the basis of future
research to form a comprehensive framework for project managers in
enhancing the project management competency.
Abstract: Social learning network analysis has drawn attention
for most researcher on e-learning research domain. This is due to the
fact that it has the capability to identify the behavior of student
during their social interaction inside e-learning. Normally, the social
network analysis (SNA) is treating the students' interaction merely as
node and edge with less meaning. This paper focuses on providing an
ontology structure of e-learning Moodle that can enrich the
relationships among students, as well as between the students and the
teacher. This ontology structure brings great benefit to the future
development of e-learning system.
Abstract: The current study aims at investigating the
relationship between the learners- integrative and instrumental
motivation and English proficiency among Iranian EFL learners. The
participants in this study consisted of 128 undergraduate university
students including 64 males and 64 females, majoring in English as a
foreign language, from Shiraz Azad University. Two research
instruments were used to gather the needed data for this study: 1)
Language Proficiency Test. 2) A scale on motivation which
determines the type of the EFL learners- motivation. Correlatin
coefficient and t-test were used to analyze the collected data and the
main result was found as follows: There is a significant relationship
between the integrative motivation and instrumental motivation with
English proficiency among EFL learners of Shiraz Azad University.
Abstract: Previous studies have indicated that one of the most
critical failure reasons of enterprise systems is the lack of knowledge
sharing and utilization across organizations. As a consequence, many
information systems researchers have paid attention to examining the
effect of absorptive capacity closely associated with knowledge
sharing and transferring on IS usage performance. A lack of
communications and interactions due to a lack of organizational
citizenship behavior might lead to weak absorptive capacity and thus
negatively influence knowledge sharing across organizations. In this
study, a theoretical model which delves into the relationship between
usage performance of enterprise systems and its determinants was
established.
Abstract: Calcium is very important for communication among
the neurons. It is vital in a number of cell processes such as secretion,
cell movement, cell differentiation. To reduce the system of reactiondiffusion
equations of [Ca2+] into a single equation, two theories
have been proposed one is excess buffer approximation (EBA) other
is rapid buffer approximation (RBA). The RBA is more realistic than
the EBA as it considers both the mobile and stationary endogenous
buffers. It is valid near the mouth of the channel. In this work we have
studied the effects of different types of buffers on calcium diffusion
under RBA. The novel thing studied is the effect of sodium ions on
calcium diffusion. The model has been made realistic by considering
factors such as variable [Ca2+], [Na+] sources, sodium-calcium
exchange protein(NCX), Sarcolemmal Calcium ATPase pump. The
proposed mathematical leads to a system of partial differential equations
which has been solved numerically to study the relationships
between different parameters such as buffer concentration, buffer
disassociation rate, calcium permeability. We have used Forward
Time Centred Space (FTCS) approach to solve the system of partial
differential equations.
Abstract: The present research was focused to investigate the
role of investment in the course of economic growth with reference to
Pakistan. The study analyzed the role of the public and private
investment and impact of the political and macroeconomic
uncertainty on economic growth of Pakistan by using the vector
autoregressive approach (VAR). In long-run both public and private
investment showed a positive impact on economic growth but the
growth was largely driven by private investment as compared to
public investment. Government consumption expenditure, economic
uncertainty and political instability hampered the economic growth of
Pakistan. In short-run the private investment positively influences the
growth but there was negative and insignificant effect of the public
investment and government consumption expenditure on the growth.
There was a positive relationship found between economic
uncertainty (proxy for inflation) and GDP in short run.
Abstract: The purpose of this study was to explore the
relationship between knowledge sharing and innovation capability,
by examining the influence of individual, organizational and
technological factors on knowledge sharing. The research is based
on a survey of 103 employees from different organizations in the
United Arab Emirates. The study is based on a model and a
questionnaire that was previously tested by Lin [1]. Thus, the study
aims at examining the validity of that model in UAE context. The
results of the research show varying degrees of correlation between
the different variables, with ICT use having the strongest relationship
with the innovation capabilities of organizations. The study also
revealed little evidence of knowledge collecting and knowledge
sharing among UAE employees.
Abstract: The purpose of the current study is to gain insight into the relative role of professional self-image (PSI) for service providers among leader-member exchange (LMX), career success. Lack of studies demonstrated that PSI of service providers affect on their CS. So, it is necessary to, according to service providers- perspective, explore the relationship among LMX and CS in hospitality industry. The result of the current study can suggest strategic directions for hospitality practitioners in terms of constructing LMX relationship, so as to make service providers realize and build their PSI, and to promote their CS. Implications of these findings for hospitality implementations as well as future research directions are subsequently discussed.
Abstract: In the globalization context and competitiveness, the role of a university is further enhanced. University is no longer confined to traditional roles. Universities need to interact with others in order to be relevant and progressive. Symbiosis relationships between the university and industry are very significant because the relationship between those two can foster economic development of a nation. In a world of fast changing technology and competition, it is necessary for the university to collaborate with industry to combine efforts fostering the diffusion of knowledge, increasing research and development, patenting innovation and commercializing products. It has become increasingly accepted that the necessity of close university-industry interactions as a mean of national economic prosperity. Therefore, this paper is aim to examine the level of linkages in university-industry interactions to which promotes the regional economic growth and development. This paper will explore the formation of linkages between the Higher Education Institution (University Technology MARA) and industries located in the Klang Valley region of Malaysia. It will present the university-industry linkages with emphasis on the type of linkages existed, the benefits of having such linkages to promote regional economic development and finally the constraints that might impede the linkages and potentials to enhance the linkages towards economic growth and development.
Abstract: The interaction among information and communication technology (ICT) industries is a recently ubiquitous phenomenon through fixed-mobile integration. To monitor the impact of interaction, previous research has mainly focused on measuring spillover effect among ICT industries using various methods. Among others, inter-industry analysis is one of the useful methods for examining spillover effect between industries. However, more complex ICT industries become, more important the impact within an industry is. Inter-industry analysis is limited in mirroring intra-relationships within an industry. Thus, this study applies the analytic network process (ANP) to measure the spillover effect, capturing all of the intra and inter-relationships. Using ANP-based intra and inter-industry analysis, the spillover effect is effectively measured, mirroring the complex structure of ICT industries. A main ICT industry and its linkages are also explored to show the current structure of ICT industries. The proposed approach is expected to allow policy makers to understand interactions of ICT industries and their impact.
Abstract: Aluminum alloy sheets have several advantages such
as the lightweight, high-specific strength and recycling efficiency.
Therefore, aluminum alloy sheets in sheet forming have been used in various areas as automotive components and so forth. During the
process of sheet forming, wrinkling which is caused by compression stress might occur and the formability of sheets was affected by
occurrence of wrinkling. A few studies of uniaxial compressive test by
using square tubes, pipes and sheets were carried out to clarify the each wrinkling behavior. However, on uniaxial compressive test,
deformation behavior of the sheets hasn-t be cleared. Then, it is necessary to clarify the relationship between the buckling behavior
and the forming conditions. In this study, the effect of dimension of the sheet in the buckling behavior on compression test of aluminum alloy sheet was cleared by experiment and FEA. As the results, the buckling
deformation was classified by three modes in terms of the distribution of equivalent plastic strain.
Abstract:
Innovation is becoming more and more important in
modern society. There are a lot of researches on different kinds of
innovation but marketing innovation is one kind of innovation that
has not been studied frequently before. Marketing innovation is
defined as a new way in which companies can market themselves to
potential or existing customers.
The study shows some key elements for marketing innovation that
are worth paying attention to when implementing marketing
innovation projects. Examples of such key elements are: paying
attention to the neglected market, suitable market segmentatio
reliable market information, public relationship, increased customer
value, combination of market factors, explore different marketing
channels and the use of technology in combination with what? Beside
the key elements for marketing innovation, we also present some
risks that may occur, such as cost, market uncertainty, information
leakage, imitation and overdependence on experience.
By proposing a set of indicators to measure marketing innovation,
the article offers solutions for marketing innovation implementation
so that any organization can achieve optimal results.
Abstract: In recent years, copulas have become very popular in
financial research and actuarial science as they are more flexible in
modelling the co-movements and relationships of risk factors as compared
to the conventional linear correlation coefficient by Pearson.
However, a precise estimation of the copula parameters is vital in
order to correctly capture the (possibly nonlinear) dependence structure
and joint tail events. In this study, we employ two optimization
heuristics, namely Differential Evolution and Threshold Accepting to
tackle the parameter estimation of multivariate t distribution models
in the EML approach. Since the evolutionary optimizer does not rely
on gradient search, the EML approach can be applied to estimation of
more complicated copula models such as high-dimensional copulas.
Our experimental study shows that the proposed method provides
more robust and more accurate estimates as compared to the IFM
approach.
Abstract: The principle of frequency and amplitude measurement of a vibrating object in water using ultrasonic speckle technique is presented in this paper. Compared with other traditional techniques, the ultrasonic speckle technique can be applied to vibration measurement of a nonmetal object with rough surface in water in a noncontact way. The relationship between speckle movement and object movement was analyzed. Based on this study, an ultrasonic speckle measurement system was set up. With this system the frequency and amplitude of an underwater vibrating cantilever beam was detected. The result shows that the experimental data is in good agreement with the calibrating data.
Abstract: The purpose of this study was to explore the
relationship between Burnout, Negative Affectivity, and
Organizational Citizenship Behavior (OCB) for social service
workers at two agencies serving homeless populations. Thirty two
subjects completed surveys. Significant correlations between major
variables and subscales were found.
Abstract: The paper is concerned with relationships between
SSME and ICTs and focuses on the role of Web 2.0 tools in
the service development process. The research presented aims at
exploring how collaborative technologies can support and improve
service processes, highlighting customer centrality and value coproduction.
The core idea of the paper is the centrality of user
participation and the collaborative technologies as enabling factors;
Wikipedia is analyzed as an example. The result of such analysis is
the identification and description of a pattern characterising specific
services in which users collaborate by means of web tools with value
co-producers during the service process. The pattern of collaborative
co-production concerning several categories of services including
knowledge based services is then discussed.