Abstract: The popularity of quality management system models
continues to grow despite the transitional crisis in 2008. Their
development is associated with demands of the new requirements for
entrepreneurs, such as risk analysis projects and more emphasis on
supervision of outsourced processes. In parallel, it is appropriate to
focus attention on the selection of companies aspiring to a quality
management system. This is particularly important in the automotive
supplier industry, where requirements transferred to the levels in the
supply chain should be clear, transparent and fairly satisfied. The
author has carried out a series of researches aimed at finding the
factors that allow for the effective implementation of the quality
management system in automotive companies. The research was
focused on four groups of companies: 1) manufacturing (parts and
assemblies for the purpose of sale or for vehicle manufacturers), 2)
service (repair and maintenance of the car) 3) services for the
transport of goods or people, 4) commercial (auto parts and vehicles).
The identified determinants were divided into two types of criteria:
internal and external, as well as hard and soft. The article presents the
hard – technical factors that an automotive company must meet in
order to achieve the goal of the quality management system
implementation.
Abstract: Students' academic achievement, along with the
effects of different variables, has been a serious concern of educators
since long ago. This study was an attempt to investigate the interplay
of Locus of Control (LOC), academic achievement and biological
variables among Iranian online EFL Learners. The participants of the
study included 100 students of different age groups and genders
studying English online at Iran Language Institute (ILI), Isfahan,
Iran. The instrument used was Trice Academic LOC questionnaire
which identifies orientations of internality or externality. The
participants' Grade Point Averages (GPAs) were used as the measure
of their academic achievement. A series of independent samples ttests
were performed on the data. The results of the study showed that
(a) there were no significant differences between male and female
participants in LOC orientation, (b) there was no relationship
between LOC and academic achievement among internal males and
females, (c) external females were better achievers than external
males, (d) and the age had no significant relationship with LOC and
academic achievement. It can be concluded that the social, cultural
patterns of genders have changed. This study might help sociologists
and psychologists as well as applied linguists in that they reflect the
recent social changes and their effects on the LOC and their
consequent implications in teaching languages.
Abstract: Community integration is a construct that an
increasing body of research has shown to have a significant impact
on the wellbeing and recovery of people with psychiatric problems.
However, there are few studies that explore which factors can be
associated and predict community integration. Moreover, community
integration has been mostly studied in minority groups, and current
literature on the definition and manifestation of community
integration in the general population is scarcer. Thus, the current
study aims to characterize community integration and explore
possible predictor variables in a sample of participants with
psychiatric problems (PP, N=183) and a sample of participants from
the general population (GP, N=211).
Results show that people with psychiatric problems present above
average values of community integration, but are significantly lower
than their healthy counterparts. It was also possible to observe that
community integration does not vary in terms of the sociodemographic
characteristics of both groups in this study. Correlation
and multiple regression showed that, among several variables that
literature present as relevant in the community integration process,
only three variables emerged as having the most explanatory value in
community integration of both groups: sense of community, basic
needs satisfaction and submission. These results also shown that
those variables have increased explanatory power in the PP sample,
which leads us to emphasize the need to address this issue in future
studies and increase the understanding of the factors that can be
involved in the promotion of community integration, in order to
devise more effective interventions in this field.
Abstract: Five palm oil ether monoesters utilized as novel
biodiesels were synthesized and structurally identified in the paper.
The investigation was made on the effect of ether species on
physicochemical properties of the palm oil ether monoesters. The
results showed that density, kinematic viscosity, smoke point, and
solidifying point increase linearly with their –CH2 group number in
certain relationships. Cetane number is enhanced whereas heat value
decreases linearly with –CH2 group number. In addition, the
influencing regularities of the volumetric content of the palm oil ether
monoesters on the fuel properties were also studied when the ether
monoesters are used as diesel fuel additives.
Abstract: Potassium borates, which are widely used in welding
and metal refining industry, as a lubricating oil additive, cement
additive, fiberglass additive and insulation compound, are one of the
important groups of borate minerals. In this study the production of a
potassium borate mineral via hydrothermal method is aimed. The
potassium source of potassium nitrate (KNO3) was used along with a
sodium source of sodium hydroxide (NaOH) and boron source of
boric acid (H3BO3). The constant parameters of reaction temperature
and reaction time were determined as 80°C and 1 h, respectively. The
molar ratios of 1:1:3 (as KNO3:NaOH:H3BO3), 1:1:4, 1:1:5, 1:1:6
and 1:1:7 were used. Following the synthesis the identifications of
the produced products were conducted by X-Ray Diffraction (XRD),
Fourier Transform Infrared Spectroscopy (FT-IR) and Raman
Spectroscopy. The results of the experiments and analysis showed in
the ratio of 1:1:6, the Santite mineral with powder diffraction file
number (pdf no.) of 01-072-1688, which is known as potassium
pentaborate (KB5O8·4H2O) was synthesized as best.
Abstract: In this paper, a new concept of closed-loop design for a
product is presented. The closed-loop design model is developed by
integrating forward design and reverse design. Based on this new
concept, a closed-loop design model for sustainable manufacturing by
integrated evaluation of forward design, reverse design, and green
manufacturing using a fuzzy analytic network process is developed. In
the design stage of a product, with a given product requirement and
objective, there can be different ways to design the detailed
components and specifications. Therefore, there can be different
design cases to achieve the same product requirement and objective.
Subsequently, in the design evaluation stage, it is required to analyze
and evaluate the different design cases. The purpose of this research is
to develop a model for evaluating the design cases by integrated
evaluating the criteria in forward design, reverse design, and green
manufacturing. A fuzzy analytic network process method is presented
for integrated evaluation of the criteria in the three models. The
comparison matrices for evaluating the criteria in the three groups are
established. The total relational values among the three groups
represent the total relational effects. In applications, a super matrix
model is created and the total relational values can be used to evaluate
the design cases for decision-making to select the final design case. An
example product is demonstrated in this presentation. It shows that the
model is useful for integrated evaluation of forward design, reverse
design, and green manufacturing to achieve a closed-loop design for
sustainable manufacturing objective.
Abstract: Damage status of RC buildings is greatly influenced
by the characteristics of the imposed ground motion. Peak Ground
Acceleration and frequency contents are considered the main two
factors that affect ground motion characteristics; hence, affecting the
seismic response of RC structures and consequently their damage
state. A detailed investigation on the combined effects of these two
factors on damage assessment of RC buildings is carried out. Twenty
one earthquake records are analyzed and arranged into three groups,
according to their frequency contents. These records are used in an
investigation to define the expected damage state that would be
attained by RC buildings, if subjected to varying ground motion
characteristics. The damage assessment is conducted through
examining drift ratios and damage indices of the overall structure and
the significant structural components of RC building. Base and story
shear of RC building model, are also investigated, for cases when the
model is subjected to the chosen twenty one earthquake records.
Nonlinear dynamic analyses are performed on a 2-dimensional model
of a 12-story RC building.
Abstract: The Speexx results revealed four main factors
affecting the success of 190 Thai sophomores as follows: 1) Future
English training should be pursued in applied Speexx development.
2) Thai students didn’t see the benefit of having an Online Language
Training Program. 3) There is a great need to educate the next
generation of learners on the benefits of Speexx within the
community. 4) A great majority of Thai Sophomores didn't know
what Speexx was.
A guideline for self-reliance planning consisted of four aspects: 1)
Development planning: by arranging groups to further improve
English abilities with the Speexx Language Training program and
encourage using Speexx into every day practice. Local communities
need to develop awareness of the usefulness of Speexx and share the
value of using the program among family and friends. 2) Humanities
and Social Science staff should develop skills using this Online
Language Training Program to expand on the benefits of Speexx
within their departments. 3) Further research should be pursued on
the Thai Students progression with Speexx and how it helps them
improve their language skills with Business English. 4) University’s
and Language centers should focus on using Speexx to encourage
learning for any language, not just English.
Abstract: Removal of the widespread used drug paracetamol
from water was investigated using activated carbon originated from
dende coconut mesocarp and babassu coconut mesocarp. Kinetic and
equilibrium data were obtained at different values of pH. Both
activated carbons showed high efficiency when pH ≤ pHPZC as the
carbonil group of paracetamol molecule are adsorbed due to
positively charged carbon surface. Microporosity also played an
important role in such process. Pseudo-second order model was better
adjusted to the kinetic results. Equilibrium data may be represented
by Langmuir equation.
Abstract: This paper investigates and compares the community
support for tourism development between two groups of minority
ethnic descendants in Malacca, Malaysia, namely the Baba-Nyonya
and Portuguese. A descriptive research design using a quantitative
method with self-reported and self-administered questionnaires
through across-sectional approach was applied. Through the
descriptive and inferential statistics, some significantly useful
insights pertaining to the issue investigated were obtained. The
research outcomes indicate that the sense of community is somewhat
more effective in small communities in terms of togetherness,
closeness and a sense of belonging compared to the slightly bigger
minority group. In addition, the sense of community attributes
through membership, influence, integration and shared emotional
connections contributes to community participation in tourism
development regardless of which ethnic group one belongs to.
Abstract: Purpose: The study aimed to assess the depressant or
antidepressant effects of several Nonsteroidal Anti-Inflammatory
Drugs (NSAIDs) in mice: the selective cyclooxygenase-2 (COX-2)
inhibitor meloxicam, and the non-selective COX-1 and COX-2
inhibitors lornoxicam, sodium metamizole, and ketorolac. The
current literature data regarding such effects of these agents are
scarce.
Materials and methods: The study was carried out on NMRI mice
weighing 20-35 g, kept in a standard laboratory environment. The
study was approved by the Ethics Committee of the University of
Medicine and Pharmacy „Carol Davila”, Bucharest. The study agents
were injected intraperitoneally, 10 mL/kg body weight (bw) 1 hour
before the assessment of the locomotor activity by cage testing (n=10
mice/ group) and 2 hours before the forced swimming tests (n=15).
The study agents were dissolved in normal saline (meloxicam,
sodium metamizole), ethanol 11.8% v/v in normal saline (ketorolac),
or water (lornoxicam), respectively. Negative and positive control
agents were also given (amitryptilline in the forced swimming test).
The cage floor used in the locomotor activity assessment was divided
into 20 equal 10 cm squares. The forced swimming test involved
partial immersion of the mice in cylinders (15/9cm height/diameter)
filled with water (10 cm depth at 28C), where they were left for 6
minutes. The cage endpoint used in the locomotor activity assessment
was the number of treaded squares. Four endpoints were used in the
forced swimming test (immobility latency for the entire 6 minutes,
and immobility, swimming, and climbing scores for the final 4
minutes of the swimming session), recorded by an observer that was
„blinded” to the experimental design. The statistical analysis used the
Levene test for variance homogeneity, ANOVA and post-hoc
analysis as appropriate, Tukey or Tamhane tests.
Results: No statistically significant increase or decrease in the
number of treaded squares was seen in the locomotor activity
assessment of any mice group. In the forced swimming test,
amitryptilline showed an antidepressant effect in each experiment, at
the 10 mg/kg bw dosage. Sodium metamizole was depressant at 100
mg/kg bw (increased the immobility score, p=0.049, Tamhane test),
but not in lower dosages as well (25 and 50 mg/kg bw). Ketorolac
showed an antidepressant effect at the intermediate dosage of 5
mg/kg bw, but not so in the dosages of 2.5 and 10 mg/kg bw,
respectively (increased the swimming score, p=0.012, Tamhane test).
Meloxicam and lornoxicam did not alter the forced swimming
endpoints at any dosage level.
Discussion: 1) Certain NSAIDs caused changes in the forced
swimming patterns without interfering with locomotion. 2) Sodium
metamizole showed a depressant effect, whereas ketorolac proved
antidepressant. Conclusion: NSAID-induced mood changes are not
class effects of these agents and apparently are independent of the
type of inhibited cyclooxygenase (COX-1 or COX-2).
Disclosure: This paper was co-financed from the European Social
Fund, through the Sectorial Operational Programme Human Resources Development 2007-2013, project number POSDRU /159
/1.5 /S /138907 "Excellence in scientific interdisciplinary research,
doctoral and postdoctoral, in the economic, social and medical fields
-EXCELIS", coordinator The Bucharest University of Economic
Studies.
Abstract: Phthalates are ubiquitous environmental pollutants
well known because of their endocrine disrupting activity in human
organism. The aim of our study was, by biological monitoring,
investigate exposure to phthalates of Roma ethnicity group i.e.
children and adults from 5 families (n=29, average age 11.8 ± 7.6
years) living in western Slovakia. Additionally, we analysed some
associations between anthropometric measures, questionnaire data
i.e. socio-economic status, eating and drinking habits, practise of
personal care products and household conditions in comparison with
concentrations of phthalate metabolites. We used for analysis of urine
samples high performance liquid chromatography and tandem mass
spectrometry (HPLC-MS/MS) to determine concentrations of
phthalate metabolites monoethyl phthalate (MEP), mono-n-butyl
phthalate (MnBP), mono-iso-butyl phthalate (MiBP), mono(2-ethyl-
5-hydroxyhexyl) phthalate (5OH-MEHP), mono(2-ethyl-5-oxohexyl)
phthalate (5oxo-MEHP) and mono(2-etylhexyl) phthalate (MEHP).
Our results indicate that ethnicity, lower socioeconomic status and
different housing conditions in Roma population can affect urinary
concentration of phthalate metabolites.
Abstract: The article represents the results of isolation and
component chromatographic analysis of essential oils of Polygonym
L. plants growing in Kazakhstan in commercial reserves at the
territory of Kazakhstan. The results of research of antiviral activity of
isolated substances to flu virus have been represented in this article.
The main pharmacophore groups in the structure of alkaloids have
been identified.
Abstract: Many factors influence the educational outcome of
students. Some of these have been studied by researchers with many
emphasizing the role of students, schools, governments, peer groups
and so on. More often than not, some of these factors influencing the
academic achievement of the students have been traced back to
parents and family; being the primary platform on which learning not
only begins but is nurtured, encouraged and developed which later
transforms to the performance of the students. This study not only
explores parental and related factors that predict academic
achievement through the review of relevant literatures but also,
investigates the influence of parental background on the academic
achievement of senior secondary school students in Ibadan North
Local Government Area of Oyo State, Nigeria. As one of the criteria
of the quality of education, students’ academic achievement was
investigated because it is most often cited as an indicator of school
effectiveness by school authorities and educationists. The data
collection was done through interviews and use of well-structured
questionnaires administered to one hundred students (100) within the
target local government. This was statistically analysed and the result
showed that parents’ attitudes towards their children’s education had
significant effect(s) on students’ self-reporting of academic
achievement. However, such factors as parental education and socioeconomic
background had no significant relationship with the
students’ self-reporting of academic achievement.
Abstract: With the flourishing development of online shopping,
an increasing number of customers see online shopping as an
entertaining experience. Because the online consumer has a double
identity as a shopper and an Internet user, online shopping should offer
hedonic values of shopping and Internet usage. The purpose of this
study is to investigate hedonic online shopping motivations from the
perspectives of traditional hedonic value and flow theory.
The study adopted a focus group interview method, including two
online and two offline interviews. Four focus groups of shoppers
consisted of online professionals, online college students, offline
professionals and offline college students. The results of the study
indicate that traditional hedonic values and dimensions of flow theory
exist in the online shopping environment. The study indicated that
online shoppers seem to appreciate being able to learn things and grow
to become competitive achievers online. Comparisons of online
hedonic motivations between groups are conducted. This study serves
as a basis for the future growth of Internet marketing.
Abstract: Kidney cancer is the most lethal urological cancer
accounting for 3% of adult malignancies. VHL, a tumor-suppressor
gene, is best known to be associated with renal cell carcinoma
(RCC). The VHL functions as negative regulator of hypoxia inducible
factors. Recent sequencing efforts have identified several novel
frequent mutations of histone modifying and chromatin remodeling
genes in ccRCC (clear cell RCC) including PBRM1 and SETD2. The
PBRM1 gene encodes the BAF180 protein, which involved in
transcriptional activation and repression of selected genes. SETD2
encodes a histone methyltransferase, which may play a role in
suppressing tumor development. In this study, RNAs of 30 paired
tumor and normal samples that were grouped according to the types
of kidney cancer and clinical characteristics of patients, including
gender and average age were examined by RT-PCR, SSCP and
sequencing techniques. VHL, PBRM1 and SETD2 expressions were
relatively down-regulated. However, statistically no significance was
found (Wilcoxon signed rank test, p>0.05). Interestingly, no mutation
was observed on the contrary of previous studies. Understanding the
molecular mechanisms involved in the pathogenesis of RCC has
aided the development of molecular-targeted drugs for kidney cancer.
Further analysis is required to identify the responsible genes rather
than VHL, PBRM1 and SETD2 in kidney cancer.
Abstract: The problems arising from unbalanced data sets
generally appear in real world applications. Due to unequal class
distribution, many researchers have found that the performance of
existing classifiers tends to be biased towards the majority class. The
k-nearest neighbors’ nonparametric discriminant analysis is a method
that was proposed for classifying unbalanced classes with good
performance. In this study, the methods of discriminant analysis are
of interest in investigating misclassification error rates for classimbalanced
data of three diabetes risk groups. The purpose of this
study was to compare the classification performance between
parametric discriminant analysis and nonparametric discriminant
analysis in a three-class classification of class-imbalanced data of
diabetes risk groups. Data from a project maintaining healthy
conditions for 599 employees of a government hospital in Bangkok
were obtained for the classification problem. The employees were
divided into three diabetes risk groups: non-risk (90%), risk (5%),
and diabetic (5%). The original data including the variables of
diabetes risk group, age, gender, blood glucose, and BMI were
analyzed and bootstrapped for 50 and 100 samples, 599 observations
per sample, for additional estimation of the misclassification error
rate. Each data set was explored for the departure of multivariate
normality and the equality of covariance matrices of the three risk
groups. Both the original data and the bootstrap samples showed nonnormality
and unequal covariance matrices. The parametric linear
discriminant function, quadratic discriminant function, and the
nonparametric k-nearest neighbors’ discriminant function were
performed over 50 and 100 bootstrap samples and applied to the
original data. Searching the optimal classification rule, the choices of
prior probabilities were set up for both equal proportions (0.33: 0.33:
0.33) and unequal proportions of (0.90:0.05:0.05), (0.80: 0.10: 0.10)
and (0.70, 0.15, 0.15). The results from 50 and 100 bootstrap samples
indicated that the k-nearest neighbors approach when k=3 or k=4 and
the defined prior probabilities of non-risk: risk: diabetic as 0.90:
0.05:0.05 or 0.80:0.10:0.10 gave the smallest error rate of
misclassification. The k-nearest neighbors approach would be
suggested for classifying a three-class-imbalanced data of diabetes
risk groups.
Abstract: This paper deals with various questions related to
functionality and providing banking services in the European union
on the Internet. Due to the fact that we live in the information
technologies era, the Internet become a new space for doing
economic and business activities in all areas, and especially important
in banking. Accepting the busy tempo of life, in the past several years
electronic banking has become necessity and a must for most users of
banking services. On a sample of 300 web sites of the banks
operating in European Union (EU) we conduct the research on the
functionality of e-banking services offered through banks web sites
with the key objective to reveal to what extent the information
technologies are used in their business operations. Characteristics of
EU banks websites will be examined and compared to the basic
groups of business activities on the web. Also some
recommendations for the successful bank web sites will be provided.
Abstract: The article represents the results of research of
antitumor activity of different structural types of plant flavonoids
extracted by authors from Polygonum L. plants in commercial
reserves at the territory of the Republic of Kazakhstan. For the first
time ever the results comparative research of antitumor activity of
plant flavonoids of different structural groups and their synthetic
derivatives have been represented. The results of determination of
toxicity of flavonoids in single parenteral infusion conditions have
been represented. Experimental substantiation of possible
mechanisms of antiproliferative and cytotoxic action of flavonoids
has been suggested. The perspectives of usage of plant flavonoids as
medications and creation of effective dosage forms of antitumor
medicines on their basis have been substantiated.
Abstract: Heat transfer of leaves is a crucial factor in optimal
operation of metabolic functions in plants. In order to quantify this
phenomenon in different leaves and investigate the influence of leaf
shape on heat transfer, natural convection for pine, orange and olive
leaves was simulated as representatives of different groups of leaf
shapes. CFD techniques were used in this simulation with the
purpose to calculate heat transfer of leaves in similar environmental
conditions. The problem was simulated for steady state and threedimensional
conditions. From obtained results, it was concluded that
heat fluxes of all three different leaves are almost identical, however,
total rate of heat transfer have highest and lowest values for orange
leaves, and pine leaves, respectively.