Correlation of Structure and Antiviral Activity of Alkaloids of Polygonum L. Plants Growing in Kazakhstan
The article represents the results of isolation and
component chromatographic analysis of essential oils of Polygonym
L. plants growing in Kazakhstan in commercial reserves at the
territory of Kazakhstan. The results of research of antiviral activity of
isolated substances to flu virus have been represented in this article.
The main pharmacophore groups in the structure of alkaloids have
been identified.
[1] P. M. Dewick, Medicinal Natural Products, N.-Y.: John Wiley & Sons
Ltd, 2002.
[2] M. Heinrich, J. Barnes, S. Gibbons, Fundamentals of Pharmacognosy
and Phytotherapy, N.-Y.: Elsevier, 2012.
[3] M. Wichtl, Herbal drugs and phytopharmaceuticals, Stuttgart: CRC
Press, 2007.
[4] B. Ozcelik, M. Aslan, I. Orhan, T. Karaoglu, Microbiol. Res., vol. 160,
pp. 159-164, 2005.
[5] B. S. Min, Y. H. Kim, M. Tomiyama, N. Nakamura, Phytother. Res.,
vol. 15, pp. 481-486, 2001.
[6] R. A. Muzychkina, D. Yu. Korulkin, Bioactive constituents of plants.
Extraction, separation and analysis, Almaty: Atamura, 2006.
[7] R. A. Muzychkina, D. Yu. Korulkin, Methodology of research of natural
metabolites, Almaty: MV-Print, 2012.
[8] L. Kursinszki, H. Hank, I. Laszlo, J. Chromatogr. A, vol. 1091, pp. 32–
39, 2005.
[9] Н. Balfour, M. E. M. Benwell, P. E. Holtom, New Engl. J. of Med., vol.
340, no. 16, pp. 1255-1268, 1999.
[10] E. Clerco, M. Vandewalle, J. Pharmacol. Exper. Therap., vol. 297, no.
1, pp. 1-10, 2000.
[11] J. M. Hu, G. D. Hsiung, Antiviral. Res., vol. 11, no. 5-6, pp. 217-232,
1989.
[12] E. Fattorusso, O. Taglialatela-Scafati, Modern Alkaloids: Structure,
Isolation, Synthesis and Biology, Weinheim: Wiley-VCH, 2008..
[13] L. J. Cseke, A. Kirakosyan, P. B. Kaufman, Natural Products from
Plants, London: CRC Press, 2006.
[14] J. Dai, R. J. Mumper, P. E. Larsen, J. C. Zwick, Molecules, vol. 15,
pp.7313-7352, 2010.
[15] K. M. Marshalla, S. S. Matsumotoa, J . A. Holdenb, Biochem.
Pharmacol., vol. 66, pp. 447-462, 2003.
[16] A. Stepanchikova, A. Lagunin, D . Filimonov, V. Poroikov, Current
Med. Chem., vol.10, pp. 225-232, 2003.
[1] P. M. Dewick, Medicinal Natural Products, N.-Y.: John Wiley & Sons
Ltd, 2002.
[2] M. Heinrich, J. Barnes, S. Gibbons, Fundamentals of Pharmacognosy
and Phytotherapy, N.-Y.: Elsevier, 2012.
[3] M. Wichtl, Herbal drugs and phytopharmaceuticals, Stuttgart: CRC
Press, 2007.
[4] B. Ozcelik, M. Aslan, I. Orhan, T. Karaoglu, Microbiol. Res., vol. 160,
pp. 159-164, 2005.
[5] B. S. Min, Y. H. Kim, M. Tomiyama, N. Nakamura, Phytother. Res.,
vol. 15, pp. 481-486, 2001.
[6] R. A. Muzychkina, D. Yu. Korulkin, Bioactive constituents of plants.
Extraction, separation and analysis, Almaty: Atamura, 2006.
[7] R. A. Muzychkina, D. Yu. Korulkin, Methodology of research of natural
metabolites, Almaty: MV-Print, 2012.
[8] L. Kursinszki, H. Hank, I. Laszlo, J. Chromatogr. A, vol. 1091, pp. 32–
39, 2005.
[9] Н. Balfour, M. E. M. Benwell, P. E. Holtom, New Engl. J. of Med., vol.
340, no. 16, pp. 1255-1268, 1999.
[10] E. Clerco, M. Vandewalle, J. Pharmacol. Exper. Therap., vol. 297, no.
1, pp. 1-10, 2000.
[11] J. M. Hu, G. D. Hsiung, Antiviral. Res., vol. 11, no. 5-6, pp. 217-232,
1989.
[12] E. Fattorusso, O. Taglialatela-Scafati, Modern Alkaloids: Structure,
Isolation, Synthesis and Biology, Weinheim: Wiley-VCH, 2008..
[13] L. J. Cseke, A. Kirakosyan, P. B. Kaufman, Natural Products from
Plants, London: CRC Press, 2006.
[14] J. Dai, R. J. Mumper, P. E. Larsen, J. C. Zwick, Molecules, vol. 15,
pp.7313-7352, 2010.
[15] K. M. Marshalla, S. S. Matsumotoa, J . A. Holdenb, Biochem.
Pharmacol., vol. 66, pp. 447-462, 2003.
[16] A. Stepanchikova, A. Lagunin, D . Filimonov, V. Poroikov, Current
Med. Chem., vol.10, pp. 225-232, 2003.
@article{"International Journal of Biological, Life and Agricultural Sciences:70034", author = "Dmitriy Yu. Korulkin and Raissa A. Muzychkina", title = "Correlation of Structure and Antiviral Activity of Alkaloids of Polygonum L. Plants Growing in Kazakhstan", abstract = "The article represents the results of isolation and
component chromatographic analysis of essential oils of Polygonym
L. plants growing in Kazakhstan in commercial reserves at the
territory of Kazakhstan. The results of research of antiviral activity of
isolated substances to flu virus have been represented in this article.
The main pharmacophore groups in the structure of alkaloids have
been identified.", keywords = "Alkaloids, antiviral, bioactive substances, isolation,
pharmacophore groups, Polygonum L.", volume = "9", number = "7", pages = "713-4", }