Abstract: In review the generalized data about different methods of extraction, separation and purification of natural and modify anthraquinones is presented. The basic regularity of an isolation process is analyzed. Action of temperature, pH, and polarity of extragent, catalysts and other factors on an isolation process is revealed.
Abstract: The article represents the results of isolation and
component chromatographic analysis of essential oils of Polygonum
L. plants growing in Kazakhstan in commercial reserves at the
territory of Kazakhstan. The results of research of antibacterial and
antifungal activity of isolated compounds have been represented.
Abstract: The article represents the results of isolation and
component chromatographic analysis of essential oils of Polygonym
L. plants growing in Kazakhstan in commercial reserves at the
territory of Kazakhstan. The results of research of antiviral activity of
isolated substances to flu virus have been represented in this article.
The main pharmacophore groups in the structure of alkaloids have
been identified.
Abstract: The article represents the results of clinical researches
of composite herbal medicinal product based on essential oils of
Sedum plants growing in Kazakhstan in commercial reserves at the
territory of Kazakhstan. The results of comparative analysis are
represented in obstetric-gynecologic practice during combined
therapy for postnatal complications, inflammatory infiltrates in the
area of surgical wounds including wounds after caesarean section.
Abstract: The article represents the results of research of
antitumor activity of different structural types of plant flavonoids
extracted by authors from Polygonum L. plants in commercial
reserves at the territory of the Republic of Kazakhstan. For the first
time ever the results comparative research of antitumor activity of
plant flavonoids of different structural groups and their synthetic
derivatives have been represented. The results of determination of
toxicity of flavonoids in single parenteral infusion conditions have
been represented. Experimental substantiation of possible
mechanisms of antiproliferative and cytotoxic action of flavonoids
has been suggested. The perspectives of usage of plant flavonoids as
medications and creation of effective dosage forms of antitumor
medicines on their basis have been substantiated.
Abstract: In review the generalized data about biological
activity of anthraquinone-containing plants and specimens on their
basis is presented. Data of traditional medicine, results of
bioscreening and clinical researches of specimens are analyzed.
Abstract: In review the generalized data about biosynthetic routs
formation anthraquinone molecules in natural cells. The basic
possibilities of various ways of biosynthesis of different quinoid
substances are shown.
Abstract: In this research paper were investigated the main
regularities of a radical bromination reaction of decalin. There had
been studied the temperature effect, durations of reaction, frequency
rate of process, a ratio of initial components, type and number of the
initiator on decalin bromination degree.
There were specified optimum conditions of synthesis of a
perbromodecalin by the method of a decalin bromination. There are
developed the technological flowchart of receiving a
perbromodecalin and the mass balance of process on the first and the
subsequent loadings of components.
The results of research of antibacterial and antifungal activity of
synthesized bromoderivatives have been represented.
Abstract: In review the generalized data about different methods
of synthesis of biological activity halogenated di-, tri- and tetrahydroxyanthraquinones
is presented. The basic regularity of a
synthesis is analyzed. Action of temperature, pH, solubility, catalysts
and other factors on a reaction product yield is revealed.
Abstract: In review the generalized data about different methods
of synthesis of biological activity aminated hydroxyanthraquinones is
presented. The basic regularity of a synthesis is analyzed. Action of
temperature, pH, solubility, catalysts and other factors on a reaction
product yield is revealed.
Abstract: In review the generalized data about different methods of synthesis of biological activity acylatedhydrohyanthraquinones is presented. The basic regularity of a synthesis is analyzed. Action of temperature, pH, solubility, catalysts and other factors on a reaction product yield is revealed.
Abstract: The Ramon preparation is received from a plant; it is destined for external treatment of inflammations in post-surgery period. The Ramon is a biogenic immune stimulator accelerating metabolism, contributing to improvement of blood indexes, having general tonic, anti-inflammatory and bactericidal effect.
Abstract: In article the data of chronic toxicity for pre-clinical
researches of Ramon preparation is described. Ramon effects to
hormone system and gastrointestinal tract; local irritative effect,
allergic, pyrogenic properties and reaction to the immune system
were studied.
Abstract: In article the data of acute toxicity for pre-clinical
researches of Ramon preparation is described. Ramon effects to
clinical characteristics of blood, cardio-vascular system, hepatotoxic
and diuretic effects were studied.
Abstract: In article the data of pre-clinical researches of Ramon
preparation is described. Antitumor activity of Ramon has been
studied on 19 strains of transplantated tumors of different
hystogenesis.