Abstract: Multipotent mesenchymal stromal cells (MSCs)
possess immunomodulatory properties. The effect of MSCs on the
crucial cellular immunity compartment – T-cells is of a special
interest. It is known that MSC tissue niche and expected milieu of
their interaction with T- cells are characterized by low oxygen
concentration, whereas the in vitro experiments usually are carried
out at a much higher ambient oxygen (20%). We firstly evaluated
immunomodulatory effects of MSCs on T-cells at tissue-related
oxygen (5%) after interaction implied cell-to-cell contacts and
paracrine factors only. It turned out that MSCs under reduced oxygen
can effectively suppress the activation and proliferation of PHAstimulated
T-cells and can provoke decrease in the production of
proinflammatory and increase in anti-inflammatory cytokines. In
hypoxia some effects were amplified (inhibition of proliferation, antiinflammatory
cytokine profile shift). This impact was more evident
after direct cell-to-cell interaction; lack of intercellular contacts could
revoke the potentiating effect of hypoxia.
Abstract: This paper presents the variation of the dynamic
characteristics of a spindle with the change of bearing preload. The
correlations between the variation of bearing preload and fundamental
modal parameters were first examined by conducting vibration tests on
physical spindle units. Experimental measurements show that the
dynamic compliance and damping ratio associated with the
dominating modes were affected to vary with variation of the bearing
preload. When the bearing preload was slightly deviated from a
standard value, the modal frequency and damping ability also vary to
different extent, which further enable the spindle to perform with
different compliance. For the spindle used in this study, a standard
preload value set on bearings would enable the spindle to behave a
higher stiffness as compared with others with a preload variation. This
characteristic can be served as a reference to examine the variation of
bearing preload of spindle in assemblage or operation.
Abstract: Analysis of real life problems often results in linear
systems of equations for which solutions are sought. The method to
employ depends, to some extent, on the properties of the coefficient
matrix. It is not always feasible to solve linear systems of equations
by direct methods, as such the need to use an iterative method
becomes imperative. Before an iterative method can be employed
to solve a linear system of equations there must be a guaranty that
the process of solution will converge. This guaranty, which must
be determined apriori, involve the use of some criterion expressible
in terms of the entries of the coefficient matrix. It is, therefore,
logical that the convergence criterion should depend implicitly on the
algebraic structure of such a method. However, in deference to this
view is the practice of conducting convergence analysis for Gauss-
Seidel iteration on a criterion formulated based on the algebraic
structure of Jacobi iteration. To remedy this anomaly, the Gauss-
Seidel iteration was studied for its algebraic structure and contrary
to the usual assumption, it was discovered that some property of the
iteration matrix of Gauss-Seidel method is only diagonally dominant
in its first row while the other rows do not satisfy diagonal dominance.
With the aid of this structure we herein fashion out an improved
version of Gauss-Seidel iteration with the prospect of enhancing
convergence and robustness of the method. A numerical section is
included to demonstrate the validity of the theoretical results obtained
for the improved Gauss-Seidel method.
Abstract: The high Peak to Average Power Ratio (PAR) in Filter
Bank Multicarrier with Offset Quadrature Amplitude Modulation
(FBMC-OQAM) can significantly reduce power efficiency and
performance. In this paper, we address the problem of PAPR
reduction for FBMC-OQAM systems using Tone Reservation (TR)
technique. Due to the overlapping structure of FBMCOQAM signals,
directly applying TR schemes of OFDM systems to FBMC-OQAM
systems is not effective. We improve the tone reservation (TR)
technique by employing sliding window with Active Constellation
Extension for the PAPR reduction of FBMC-OQAM signals, called
sliding window tone reservation Active Constellation Extension
(SW-TRACE) technique. The proposed SW-TRACE technique uses
the peak reduction tones (PRTs) of several consecutive data
blocks to cancel the peaks of the FBMC-OQAM signal inside a
window, with dynamically extending outer constellation points in
active(data-carrying) channels, within margin-preserving constraints,
in order to minimize the peak magnitude. Analysis and simulation
results compared to the existing Tone Reservation (TR) technique for
FBMC/OQAM system. The proposed method SW-TRACE has better
PAPR performance and lower computational complexity.
Abstract: This work presents the modelling and simulation of
saponification of ethyl acetate in the presence of sodium hydroxide in
a plug flow reactor using Aspen Plus simulation software. Plug flow
reactors are widely used in the industry due to the non-mixing
property. The use of plug flow reactors becomes significant when
there is a need for continuous large scale reaction or fast reaction.
Plug flow reactors have a high volumetric unit conversion as the
occurrence for side reactions is minimum. In this research Aspen Plus
V8.0 has been successfully used to simulate the plug flow reactor. In
order to simulate the process as accurately as possible HYSYS Peng-
Robinson EOS package was used as the property method. The results
obtained from the simulation were verified by the experiment carried
out in the EDIBON plug flow reactor module. The correlation
coefficient (r2) was 0.98 and it proved that simulation results
satisfactorily fit for the experimental model. The developed model
can be used as a guide for understanding the reaction kinetics of a
plug flow reactor.
Abstract: Lead (Pb) poisoning is one of the most common and
preventable environmental health problems. There are different
sources of environmental pollution with lead as lead alkyl additives
in petrol and manufacturing processes. Pb in the atmosphere can be
deposited in urban soils, and may then be re-suspended to re-enter the
atmosphere. This could increase human exposure to Pb and cause
long-term health effects. Thus, monitoring Pb pollution is considered
one of the major tasks in controlling pollution. Scalp hair can be
utilized for the determination of lead (Pb) concentration. It provides a
lasting record of metal intakes of weeks or even months, and for most
metals, their accumulation in hair reflects their accumulation in the
whole body. This work was conducted to investigate the
concentration of lead in male scalp hair of Cairo (residential-traffic
and residential-industrial) and rural residents after twenty years of
phasing out of leaded gasoline. Results indicated that the mean
concentration of lead in hair of residential-traffic (9.7552 μg/g ±0.71)
and residential-industrial (12.3288 μg/g ±1.13) was significantly
higher than that in rural residents (4.7327 μg/g ±0.67). The mean
concentration of lead in hair of resident’s industrial areas was the
highest among Cairo residents and not the traffic areas as it was
before phasing out of leaded gasoline. Twenty years of phasing out of
leaded gasoline in Cairo has greatly improved the lead pollution
among residents of traffic areas, but industrial areas residents were
still suffering from lead pollution, which needs more efforts to
control the sources of lead pollution.
Abstract: Biological conversion of biomass to methane has
received increasing attention in recent years. Grasses have been
explored for their potential anaerobic digestion to methane. In this
review, extensive literature data have been tabulated and classified.
The influences of several parameters on the potential of these
feedstocks to produce methane are presented. Lignocellulosic
biomass represents a mostly unused source for biogas and ethanol
production. Many factors, including lignin content, crystallinity of
cellulose, and particle size, limit the digestibility of the hemicellulose
and cellulose present in the lignocellulosic biomass. Pretreatments
have used to improve the digestibility of the lignocellulosic biomass.
Each pretreatment has its own effects on cellulose, hemicellulose and
lignin, the three main components of lignocellulosic biomass. Solidstate
anaerobic digestion (SS-AD) generally occurs at solid
concentrations higher than 15%. In contrast, liquid anaerobic
digestion (AD) handles feedstocks with solid concentrations between
0.5% and 15%. Animal manure, sewage sludge, and food waste are
generally treated by liquid AD, while organic fractions of municipal
solid waste (OFMSW) and lignocellulosic biomass such as crop
residues and energy crops can be processed through SS-AD. An
increase in operating temperature can improve both the biogas yield
and the production efficiency, other practices such as using AD
digestate or leachate as an inoculant or decreasing the solid content
may increase biogas yield but have negative impact on production
efficiency. Focus is placed on substrate pretreatment in anaerobic
digestion (AD) as a means of increasing biogas yields using today’s
diversified substrate sources.
Abstract: Application of hulls processing technologies, based on high-concentrated energy sources (laser and plasma technologies), allow improve shipbuilding production. It is typical for high-speed vessels construction using steel and aluminum alloys with high precision hulls required. Report describes high-performance technologies for plasma welding (using direct current of reversed polarity), laser, and hybrid laser-arc welding of hulls structures developed by JSC “SSTC”
Abstract: It is known that residual welding deformations give
negative effect to processability and operational quality of welded
structures, complicating their assembly and reducing strength.
Therefore, selection of optimal technology, ensuring minimum
welding deformations, is one of the main goals in developing a
technology for manufacturing of welded structures.
Through years, JSC SSTC has been developing a theory for
estimation of welding deformations and practical activities for
reducing and compensating such deformations during welding
process. During long time a methodology was used, based on analytic
dependence. This methodology allowed defining volumetric changes
of metal due to welding heating and subsequent cooling. However,
dependences for definition of structures deformations, arising as a
result of volumetric changes of metal in the weld area, allowed
performing calculations only for simple structures, such as units, flat
sections and sections with small curvature. In case of complex 3D
structures, estimations on the base of analytic dependences gave
significant errors.
To eliminate this shortage, it was suggested to use finite elements
method for resolving of deformation problem. Here, one shall first
calculate volumes of longitudinal and transversal shortenings of
welding joints using method of analytic dependences and further,
with obtained shortenings, calculate forces, which action is
equivalent to the action of active welding stresses. Further, a finiteelements
model of the structure is developed and equivalent forces
are added to this model. Having results of calculations, an optimal
sequence of assembly and welding is selected and special measures to
reduce and compensate welding deformations are developed and
taken.
Abstract: The emergence of the Semantic Web technology
increases day by day due to the rapid growth of multiple web pages.
Many standard formats are available to store the semantic web data.
The most popular format is the Resource Description Framework
(RDF). Querying large RDF graphs becomes a tedious procedure
with a vast increase in the amount of data. The problem of query
optimization becomes an issue in querying large RDF graphs.
Choosing the best query plan reduces the amount of query execution
time. To address this problem, nature inspired algorithms can be used
as an alternative to the traditional query optimization techniques. In
this research, the optimal query plan is generated by the proposed
SAPSO algorithm which is a hybrid of Simulated Annealing (SA)
and Particle Swarm Optimization (PSO) algorithms. The proposed
SAPSO algorithm has the ability to find the local optimistic result
and it avoids the problem of local minimum. Experiments were
performed on different datasets by changing the number of predicates
and the amount of data. The proposed algorithm gives improved
results compared to existing algorithms in terms of query execution
time.
Abstract: High temperature deformation behavior of cast
Fe-20Cr-5Al alloy has been investigated in this study by performing
tensile and compression tests at temperatures from 1100 to 1200oC.
Rectangular ingots of which the dimensions were 300×300×100 in
millimeter were cast using vacuum induction melting. Phase
equilibrium was calculated using the FactSage®, thermodynamic
software and database. Tensile strength of cast Fe-20Cr-5Al alloy was
4 MPa at 1200oC. With temperature decreased, tensile strength
increased rapidly and reached up to 13 MPa at 1100oC. Elongation
also increased from 18 to 80% with temperature decreased from
1200oC to 1100oC. Microstructure observation revealed that M23C6
carbide was precipitated along the grain boundary and within the
matrix.
Abstract: Paper deals with analysis of strategic management
methods in non-profit making organization in the Czech Republic.
Strategic management represents an aggregate of methods and
approaches that can be applied for managing organizations - in this
article the organizations which associate owners and keepers of nonstate
forest properties. Authors use these methods of strategic
management: analysis of stakeholders, SWOT analysis and
questionnaire inquiries. The questionnaire was distributed
electronically via e-mail. In October 2013 we obtained data from a
total of 84 questionnaires. Based on the results the authors
recommend the using of confrontation strategy which improves the
competitiveness of non-profit making organizations.
Abstract: This study investigates the effect of moisture
conditioning on the Indirect Tensile Strength (ITS) of asphalt
concrete. As a first step, cylindrical samples of 100 mm diameter and
50 mm thick were prepared using a Superpave gyratory compactor.
Next, the samples were conditioned using Moisture Induced
Susceptibility Test (MIST) device at different numbers of moisture
conditioning cycles. In the MIST device, samples are subjected water
pressure through the sample pores cyclically. The MIST conditioned
samples were tested for ITS. Results show that the ITS does not
change significantly with MIST conditioning at the specific pressure
and cycles adopted in this study.
Abstract: Electronic market place plays an important
intermediary role for connecting dealers and retail customers. The
main aim of this paper is to design a value co-creation model in
used-car auctions. More specifically, the study has been designed in
order to describe the process of value co-creation in used-car auctions,
to explore the co-created values in used-car auctions, and finally
conclude the paper indicating the future research directions. Our
analysis shows that economic values as well as non-economic values
are co-created in used-car auctions. In addition, this paper contributes
to the academic society broadening the view of value co-creation in
service science.
Abstract: Bureaucracy reform program drives Indonesian
government to change their management to enhance their
organizational performance. Information technology became one of
strategic plan that organization tried to improve. Knowledge
management system is one of information system that supporting
knowledge management implementation in government which
categorized as people perspective, because this system has high
dependency in human interaction and participation. Strategic plan for
developing knowledge management system can be determine using
some of information system strategic methods. This research
conducted to define type of strategic method of information system,
stage of activity each method, strength and weakness. Literature
review methods used to identify and classify strategic methods of
information system, differentiate method type, categorize common
activities, strength and weakness. Result of this research are
determine and compare six strategic information system methods,
Balanced Scorecard and Risk Analysis believe as common strategic
method that usually used and have the highest excellence strength.
Abstract: This paper presents the application of finite dynamic
programming, specifically the "Markov Chain" model, as part of the
decision making process of a company in the cosmetics sector located
in the vicinity of Bogota DC. The objective of this process was to
decide whether the company should completely reconstruct its
wastewater treatment plant or instead optimize the plant through the
addition of equipment. The goal of both of these options was to make
the required improvements in order to comply with parameters
established by national legislation regarding the treatment of waste
before it is released into the environment. This technique will allow
the company to select the best option and implement a solution for
the processing of waste to minimize environmental damage and the
acquisition and implementation costs.
Abstract: The objectives of this research were to study the
influencing factors that contributed to the success of e-collaborative
in e-commerce of B2C (Business to Customer) business in Bangkok,
Thailand. The influencing factors included organization, people,
information technology and the process of e-collaborative. A
questionnaire was used to collect data from 200 small e-commerce
businesses and the path analysis was utilized as the tool for data
analysis.
By using the path analysis, it was revealed that the factors
concerning with organization, people and information technology
played an influence on e-collaborative process and the success of ecollaborative,
whereas the process of e-collaborative factor
manipulated its success. The findings suggested that B2C ecommerce
business in Thailand should opt in improvement approach
in terms of managerial structure, leaderships, staff’s skills and
knowledge, and investment of information technology in order to
capacitate higher efficiency of e-collaborative process that would
result in profit and competitive advantage.
Abstract: ‘Steganalysis’ is one of the challenging and attractive interests for the researchers with the development of information hiding techniques. It is the procedure to detect the hidden information from the stego created by known steganographic algorithm. In this paper, a novel feature based image steganalysis technique is proposed. Various statistical moments have been used along with some similarity metric. The proposed steganalysis technique has been designed based on transformation in four wavelet domains, which include Haar, Daubechies, Symlets and Biorthogonal. Each domain is being subjected to various classifiers, namely K-nearest-neighbor, K* Classifier, Locally weighted learning, Naive Bayes classifier, Neural networks, Decision trees and Support vector machines. The experiments are performed on a large set of pictures which are available freely in image database. The system also predicts the different message length definitions.
Abstract: Second line antiretroviral therapy (ART) regimen is
used when patients fail their first line regimen. There are many
factors such as non-adherence, drug resistance as well as virological
and immunological failure that lead to second line highly active
antiretroviral therapy (HAART) regimen treatment failure. This study
was aimed at determining predictor factors to treatment failure with
second line HAART and analyzing median survival time.
An observational, retrospective study was conducted in Sungai
Buloh Hospital (HSB) to assess current status of HIV patients treated
with second line HAART regimen. Convenience sampling was used
and 104 patients were included based on the study’s inclusion and
exclusion criteria. Data was collected for six months i.e. from July
until December 2013. Data was then analysed using SPSS version 18.
Kaplan-Meier and Cox regression analyses were used to measure
median survival times and predictor factors for treatment failure.
The study population consisted mainly of male subjects, aged 30-
45 years, who were heterosexual, and had HIV infection for less than
6 years. The most common second line HAART regimen given was
lopinavir/ritonavir (LPV/r)-based combination. Kaplan-Meier
analysis showed that patients on LPV/r demonstrated longer median
survival times than patients on indinavir/ritonavir (IDV/r) based
combination (p
Abstract: A methodology is proposed for estimating the optical
attenuation and proportional depth variation of shallow inland water.
The process is demonstrated with EO-1 Hyperion hyperspectral and
IRS-P6 LISS-3 multispectral images of Kolkata city nearby area
centered around 22º33′ N 88º26′ E. The attenuation coefficient of
water was found to change with fine resolution of wavebands and in
presence of suspended organic matter in water.