Abstract: Matrix metalloproteinase-3 (MMP3) is key member
of the MMP family, and is known to be present in coronary
atherosclerotic. Several studies have demonstrated that MMP-3
5A/6A polymorphism modify each transcriptional activity in allele
specific manner. We hypothesized that this polymorphism may play
a role as risk factor for development of coronary stenosis. The aim of
our study was to estimate MMP-3 (5A/6A) gene polymorphism on
interindividual variability in risk for coronary stenosis in an Iranian
population.DNA was extracted from white blood cells and genotypes
were obtained from coronary stenosis cases (n=95) and controls
(n=100) by PCR (polymerase chain reaction) and restriction
fragment length polymorphism techniques. Significant differences
between cases and controls were observed for MMP3 genotype
frequencies (X2=199.305, p< 0.001); the 6A allele was less
frequently seen in the control group, compared to the disease group
(85.79 vs. 78%, 6A/6A+5A/6A vs. 5A/5A, P≤0.001). These data
imply the involvement of -1612 5A/6A polymorphism in coronary
stenosis, and suggest that probably the 6A/6A MMP-3 genotype is a
genetic susceptibility factor for coronary stenosis.
Abstract: In this paper, the effect of width and height of the
model on the earthquake response in the finite element method is
discussed. For this purpose an earth dam as a soil structure under
earthquake has been considered. Various dam-foundation models are
analyzed by Plaxis, a finite element package for solving geotechnical
problems. The results indicate considerable differences in the seismic
responses.
Abstract: This paper describes the design of a programmable
FSK-modulator based on VCO and its implementation in 0.35m
CMOS process. The circuit is used to transmit digital data at
100Kbps rate in the frequency range of 400-600MHz. The design
and operation of the modulator is discussed briefly. Further the
characteristics of PLL, frequency synthesizer, VCO and the whole
design are elaborated. The variation among the proposed and tested
specifications is presented. Finally, the layout of sub-modules, pin
configurations, final chip and test results are presented.
Abstract: The utilize of renewable energy sources becomes
more crucial and fascinatingly, wider application of renewable
energy devices at domestic, commercial and industrial levels is not
only affect to stronger awareness but also significantly installed
capacities. Moreover, biomass principally is in form of woods and
converts to be energy for using by humans for a long time.
Gasification is a process of conversion of solid carbonaceous fuel
into combustible gas by partial combustion. Many gasified models
have various operating conditions because the parameters kept in
each model are differentiated. This study applied the experimental
data including three inputs variables including biomass consumption;
temperature at combustion zone and ash discharge rate and gas flow
rate as only one output variable. In this paper, response surface
methods were applied for identification of the gasified system
equation suitable for experimental data. The result showed that linear
model gave superlative results.
Abstract: Repetitive control and feedback dithering modulation
are applied to a single-phase voltage source inverter, with an aim to
eliminate harmonics and stabilize the inverter under load variations.
The proposed control and modulation scheme comprise multiple loops
of feedback, which helps improve inverter performance and
robustness. Experimental results show that the designed inverter
exhibits very low distortion at its output with THD of about 0.3%
under different load variations.
Abstract: Nowadays there are several grid connected converter
in the grid system. These grid connected converters are generally the
converters of renewable energy sources, industrial four quadrant
drives and other converters with DC link. These converters are
connected to the grid through a three phase bridge. The standards
prescribe the maximal harmonic emission which could be easily
limited with high switching frequency. The increased switching
losses can be reduced to the half with the utilization of the wellknown
Flat-top modulation. The suggested control method is the
expansion of the Flat-top modulation with which the losses could be
also reduced to the half compared to the Flat-top modulation.
Comparing to traditional control these requirements can be
simultaneously satisfied much better with the DLF (DC Link
Floating) method.
Abstract: In this paper, an accurate theoretical analysis for the achievable average channel capacity (in the Shannon sense) per user of a hybrid cellular direct-sequence/fast frequency hopping code-division multiple-access (DS/FFH-CDMA) system operating in a Rayleigh fading environment is presented. The analysis covers the downlink operation and leads to the derivation of an exact mathematical expression between the normalized average channel capacity available to each system-s user, under simultaneous optimal power and rate adaptation and the system-s parameters, as the number of hops per bit, the processing gain applied, the number of users per cell and the received signal-tonoise power ratio over the signal bandwidth. Finally, numerical results are presented to illustrate the proposed mathematical analysis.
Abstract: The widely used Total Variation de-noising algorithm can preserve sharp edge, while removing noise. However, since fixed regularization parameter over entire image, small details and textures are often lost in the process. In this paper, we propose a modified Total Variation algorithm to better preserve smaller-scaled features. This is done by allowing an adaptive regularization parameter to control the amount of de-noising in any region of image, according to relative information of local feature scale. Experimental results demonstrate the efficient of the proposed algorithm. Compared with standard Total Variation, our algorithm can better preserve smaller-scaled features and show better performance.
Abstract: The object of this paper is to design and analyze a
proportional – integral (PI) control for positive output elementary
super lift Luo converter (POESLLC), which is the start-of-the-art
DC-DC converter. The positive output elementary super lift Luo
converter performs the voltage conversion from positive source
voltage to positive load voltage. This paper proposes a
development of PI control capable of providing the good static and
dynamic performance compared to proportional – integralderivative
(PID) controller. Using state space average method
derives the dynamic equations describing the positive output
elementary super lift luo converter and PI control is designed. The
simulation model of the positive output elementary super lift Luo
converter with its control circuit is implemented in
Matlab/Simulink. The PI control for positive output elementary
super lift Luo converter is tested for transient region, line changes,
load changes, steady state region and also for components
variations.
Abstract: This study aimed to present the mechanical
performance evaluation of the dynamic hip screw (DHS) for
trochanteric fracture by means of finite element method. The
analyses were performed based on stainless steel and titanium
implant material definitions at various stages of bone healing and
including implant removal. The assessment of the mechanical
performance used two parameters, von Mises stress to evaluate the
strength of bone and implant and elastic strain to evaluate fracture
stability. The results show several critical aspects of dynamic hip
screw for trochanteric fracture stabilization. In the initial stage of
bone healing process, partial weight bearing should be applied to
avoid the implant failure. In the late stage of bone healing, stainless
steel implant should be removed.
Abstract: In this paper, we present an experimental testing for
a new algorithm that determines an optimal controller-s coefficients
for output variance reduction related to Linear Time Invariant (LTI)
Systems. The algorithm features simplicity in calculation, generalization
to minimal and non-minimal phase systems, and could be
configured to achieve reference tracking as well as variance reduction
after compromising with the output variance. An experiment of DCmotor
velocity control demonstrates the application of this new
algorithm in designing the controller. The results show that the
controller achieves minimum variance and reference tracking for a
preset velocity reference relying on an identified model of the motor.
Abstract: In the present work steady inviscid hypersonic flows
are calculated by approximate Method. Maslens' inverse method is the chosen approximate method. For the inverse problem, parabolic
shock shape is chosen for the two-dimensional flow, and the body shape and flow field are calculated using Maslen's method. For the axisymmetric inverse problem paraboloidal shock is chosen and the
surface distribution of pressure is obtained.
Abstract: The distribution, enrichment, accumulation, and potential ecological risk of copper (Cu) in the surface sediments of northern Kaohsiung Harbor, Taiwan were investigated. Sediment samples from 12 locations of northern Kaohsiung Harbor were collected and characterized for Cu, aluminum, water content, organic matter, total nitrogen, total phosphorous, total grease and grain size. Results showed that the Cu concentrations varied from 6.9–244 mg/kg with an average of 109±66 mg/kg. The spatial distribution of Cu reveals that the Cu concentration is relatively high in the river mouth region, and gradually diminishes toward the harbor entrance region. This indicates that upstream industrial and municipal wastewater discharges along the river bank are major sources of Cu pollution. Results from the enrichment factor and geo-accumulation index analyses imply that the sediments collected from the river mouth can be characterized between moderate and moderately severe degree enrichment and between none to medium and moderate accumulation of Cu, respectively. However, results of potential ecological risk index indicate that the sediment has low ecological potential risk.
Abstract: In rapidly changing market environment, firms are investing a lot of time and resources into new product development (NPD) projects to make profit and to obtain competitive advantage. However, failure rate of NPD projects is becoming high due to various internal and external risks which hinder successful NPD projects. To reduce the failure rate, it is critical that risks have to be managed effectively and efficiently through good strategy, and treated by optimal responses to minimize risk cost. Four strategies are adopted to handle the risks in this study. The optimal responses are characterized by high reduction of risk costs with high efficiency. This study suggests a framework to decide the optimal responses considering the core risks, risk costs, response efficiency and response costs for successful NPD projects. Both binary particles warm optimization (BPSO) and multi-objective particle swarm optimization (MOPSO) methods are mainly used in the framework. Although several limitations exist in use for real industries, the frame work shows good strength for handling the risks with highly scientific ways through an example.
Abstract: In this paper, the statistical properties of filtered or convolved signals are considered by deriving the resulting density functions as well as the exact mean and variance expressions given a prior knowledge about the statistics of the individual signals in the filtering or convolution process. It is shown that the density function after linear convolution is a mixture density, where the number of density components is equal to the number of observations of the shortest signal. For circular convolution, the observed samples are characterized by a single density function, which is a sum of products.
Abstract: This paper investigates the robust stability of uncertain neutral system with time-varying delay. By using Lyapunov method and linear matrix inequality technology, new delay-dependent stability criteria are obtained and formulated in terms of linear matrix inequalities (LMIs), which can be easy to check the robust stability of the considered systems. Numerical examples are given to indicate significant improvements over some existing results.
Abstract: Artifact free photoplethysmographic (PPG) signals are
necessary for non-invasive estimation of oxygen saturation (SpO2) in
arterial blood. Movement of a patient corrupts the PPGs with motion
artifacts, resulting in large errors in the computation of Sp02. This
paper presents a study on using Kalman Filter in an innovative way
by modeling both the Artillery Blood Pressure (ABP) and the
unwanted signal, additive motion artifact, to reduce motion artifacts
from corrupted PPG signals. Simulation results show acceptable
performance regarding LMS and variable step LMS, thus
establishing the efficacy of the proposed method.
Abstract: Truss optimization problem has been vastly studied
during the past 30 years and many different methods have been
proposed for this problem. Even though most of these methods
assume that the design variables are continuously valued, in reality,
the design variables of optimization problems such as cross-sectional
areas are discretely valued. In this paper, an improved hill climbing
and an improved simulated annealing algorithm have been proposed
to solve the truss optimization problem with discrete values for crosssectional
areas. Obtained results have been compared to other
methods in the literature and the comparison represents that the
proposed methods can be used more efficiently than other proposed
methods
Abstract: Roundabout work on the principle of circulation and
entry flows, where the maximum entry flow rates depend largely on
circulating flow bearing in mind that entry flows must give away to
circulating flows. Where an existing roundabout has a road hump
installed at the entry arm, it can be hypothesized that the kinematics
of vehicles may prevent the entry arm from achieving optimum
performance. Road humps are traffic calming devices placed across
road width solely as speed reduction mechanism. They are the
preferred traffic calming option in Malaysia and often used on single
and dual carriageway local routes. The speed limit on local routes is
30mph (50 km/hr). Road humps in their various forms achieved the
biggest mean speed reduction (based on a mean speed before traffic
calming of 30mph) of up to 10mph or 16 km/hr according to the UK
Department of Transport. The underlying aim of reduced speed
should be to achieve a 'safe' distribution of speeds which reflects the
function of the road and the impacts on the local community.
Constraining safe distribution of speeds may lead to poor drivers
timing and delayed reflex reaction that can probably cause accident.
Previous studies on road hump impact have focused mainly on speed
reduction, traffic volume, noise and vibrations, discomfort and delay
from the use of road humps. The paper is aimed at optimal entry and
circulating flow induced by road humps. Results show that
roundabout entry and circulating flow perform better in
circumstances where there is no road hump at entrance.
Abstract: Gene, principal unit of inheritance, is an ordered
sequence of nucleotides. The genes of eukaryotic organisms include
alternating segments of exons and introns. The region of
Deoxyribonucleic acid (DNA) within a gene containing instructions
for coding a protein is called exon. On the other hand, non-coding
regions called introns are another part of DNA that regulates gene
expression by removing from the messenger Ribonucleic acid (RNA)
in a splicing process. This paper proposes to determine splice
junctions that are exon-intron boundaries by analyzing DNA
sequences. A splice junction can be either exon-intron (EI) or intron
exon (IE). Because of the popularity and compatibility of the
artificial neural network (ANN) in genetic fields; various ANN
models are applied in this research. Multi-layer Perceptron (MLP),
Radial Basis Function (RBF) and Generalized Regression Neural
Networks (GRNN) are used to analyze and detect the splice junctions
of gene sequences. 10-fold cross validation is used to demonstrate
the accuracy of networks. The real performances of these networks
are found by applying Receiver Operating Characteristic (ROC)
analysis.