Abstract: A numerical model has been developed to investigate the thermally triggered release kinetics for drug delivery using phase change material as shell of microcapsules. Biocompatible material n-Eicosane is used as demonstration. PCM shell of microcapsule will remain in solid form after the drug is taken, so the drug will be encapsulated by the shell, and will not be released until the target body part of lesion is exposed to external heat source, which will thermally trigger the release kinetics, leading to solid-to-liquid phase change. The findings can lead to better understanding on the key effects influencing the phase change process for drug delivery applications. The facile approach to release drug from core/shell structure of microcapsule can be well integrated with organic solvent free fabrication of microcapsules, using double emulsion as template in microfluidic aqueous two phase system.
Abstract: Family has a crucial role in maintaining the
physical, social and mental health of the children. Most of the
mental and anxiety problems of children reflect the complex
interpersonal situations among family members, especially parents.
In other words, anxiety problems of the children are correlated
with deficit relationships of family members and improper
childrearing styles. The parental child rearing styles leads to
positive and negative consequences which affect the children’s
mental health. Therefore, the present research was aimed to
compare the parental childrearing styles and anxiety of children
with stuttering and normal population. It was also aimed to study
the relationship between parental child rearing styles and anxiety
of children. The research sample included 54 boys with stuttering
and 54 normal boys who were selected from the children (boys) of
Tehran, Iran in the age range of 5 to 8 years in 2013. In order to
collect data, Baum-rind Childrearing Styles Inventory and Spence
Parental Anxiety Inventory were used. Appropriate descriptive
statistical methods and multivariate variance analysis and t test for
independent groups were used to test the study hypotheses.
Statistical data analyses demonstrated that there was a significant
difference between stuttering boys and normal boys in anxiety (t =
7.601, p< 0.01); but there was no significant difference between
stuttering boys and normal boys in parental childrearing styles (F =
0.129). There was also not found significant relationship between
parental childrearing styles and children anxiety (F = 0.135, p<
0.05). It can be concluded that the influential factors of children’s
society are parents, school, teachers, peers and media. So, parental
childrearing styles are not the only influential factors on anxiety of
children, and other factors including genetic, environment and
child experiences are effective in anxiety as well. Details are
discussed.
Abstract: Hydrothermal liquefaction (HTL) is a technique for obtaining clean biofuel from biomass in the presence of heat and pressure in an aqueous medium which leads to a decomposition of this biomass to the formation of various products. A role of operating conditions is essential for the bio-oil and other products’ yield and also quality of the products. The effects of these parameters were investigated in regards to the composition and yield of the products. Chlorellaceae microalgae were tested under different HTL conditions to clarify suitable conditions for extracting bio-oil together with value-added co-products. Firstly, different microalgae loading rates (5-30%) were tested and found that this parameter has not much significant to product yield. Therefore, 10% microalgae loading rate was selected as a proper economical solution for conditioned schedule at 250oC and 30 min-reaction time. Next, a range of temperature (210-290oC) was applied to verify the effects of each parameter by keeping the reaction time constant at 30 min. The results showed no linkage with the increase of the reaction temperature and some reactions occurred that lead to different product yields. Moreover, some nutrients found in the aqueous product are possible to be utilized for nutrient recovery.
Abstract: Rice straw is lignocellulosic biomass which can be utilized as substrate for the biogas production. However, due to the property and composition of rice straw, it is difficult to be degraded by hydrolysis enzymes. One of the pretreatment methods that modify such properties of lignocellulosic biomass is the application of lignocellulose-degrading microbial consortia. The aim of this study is to investigate the effect of microbial consortia to enhance biogas production. To select the high efficient consortium, cellulase enzymes were extracted and their activities were analyzed. The results suggested that microbial consortium culture obtained from cattle manure is the best candidate compared to decomposed wood and horse manure. A microbial consortium isolated from cattle manure was then mixed with anaerobic sludge and used as inoculum for biogas production. The optimal conditions for biogas production were investigated using response surface methodology (RSM). The tested parameters were the ratio of amount of microbial consortium isolated and amount of anaerobic sludge (MI:AS), substrate to inoculum ratio (S:I) and temperature. Here, the value of the regression coefficient R2 = 0.7661 could be explained by the model which is high to advocate the significance of the model. The highest cumulative biogas yield was 104.6 ml/g-rice straw at optimum ratio of MI:AS, ratio of S:I, and temperature of 2.5:1, 15:1 and 44°C respectively.
Abstract: This work proposes a data-driven multiscale based
quantitative measures to reveal the underlying complexity of
electroencephalogram (EEG), applying to a rodent model of
hypoxic-ischemic brain injury and recovery. Motivated by that real
EEG recording is nonlinear and non-stationary over different
frequencies or scales, there is a need of more suitable approach over
the conventional single scale based tools for analyzing the EEG data.
Here, we present a new framework of complexity measures
considering changing dynamics over multiple oscillatory scales. The
proposed multiscale complexity is obtained by calculating entropies of
the probability distributions of the intrinsic mode functions extracted
by the empirical mode decomposition (EMD) of EEG. To quantify
EEG recording of a rat model of hypoxic-ischemic brain injury
following cardiac arrest, the multiscale version of Tsallis entropy is
examined. To validate the proposed complexity measure, actual EEG
recordings from rats (n=9) experiencing 7 min cardiac arrest followed
by resuscitation were analyzed. Experimental results demonstrate that
the use of the multiscale Tsallis entropy leads to better discrimination
of the injury levels and improved correlations with the neurological
deficit evaluation after 72 hours after cardiac arrest, thus suggesting an
effective metric as a prognostic tool.
Abstract: This paper presents dynamic models of distributed
generators (DG) and investigates dynamic behavior of the DG units
in the micro grid system. The DG units include photovoltaic and fuel
cell sources. The voltage source inverter is adopted since the
electronic interface which can be equipped with its controller to keep
stability of the micro grid during small signal dynamics. This paper
also introduces power management strategies and implements the DG
load sharing concept to keep the micro grid operation in gridconnected
and islanding modes of operation. The results demonstrate
the operation and performance of the photovoltaic and fuel cell as
distributed generators in a micro grid. The entire control system in
the micro grid is developed by combining the benefits of the power
control and the voltage control strategies. Simulation results are all
reported, confirming the validity of the proposed control technique.
Abstract: Control of honey frauds is needed in Ecuador to
protect bee keepers and consumers because simple syrups and new
syrups with eucalyptus are sold as genuine honeys. Authenticity of
Ecuadorian commercial honeys was tested with a vortex emulsion
consisting on one volume of honey:water (1:1) dilution, and two
volumes of diethyl ether. This method allows a separation of phases
in one minute to discriminate genuine honeys that form three phase
and fake honeys that form two phases; 34 of the 42 honeys analyzed
from five provinces of Ecuador were genuine. This was confirmed
with 1H NMR spectra of honey dilutions in deuterated water with an
enhanced amino acid region with signals for proline, phenylalanine
and tyrosine. Classic quality indicators were also tested with this
method (sugars, HMF), indicators of fermentation (ethanol, acetic
acid), and residues of citric acid used in the syrup manufacture. One
of the honeys gave a false positive for genuine, being an admixture of
genuine honey with added syrup, evident for the high sucrose.
Sensory analysis was the final confirmation to recognize the honey
groups studied here, namely honey produced in combs by Apis
mellifera, fake honey, and honey produced in cerumen pots by
Geotrigona, Melipona, and Scaptotrigona. Chloroform extractions of
honey were also done to search lipophilic additives in NMR spectra.
This is a valuable contribution to protect honey consumers, and to
develop the beekeeping industry in Ecuador.
Abstract: In emerging economies, recycling is an opportunity
for the cities to increase the lifespan of sanitary landfills, reduce the
costs of the solid waste management, decrease the environmental
problems of the waste treatment through reincorporate waste in the
productive cycle and protect and develop people’s livelihoods of
informal waste pickers. However, few studies have analysed the
possibilities and strategies to integrate formal and informal sectors in
the solid waste management for the benefit of both. This study seek
to make a strength, weakness, opportunity, and threat (SWOT)
analysis in three recycling associations of Bogotá with the aim to
understand and determine the situation of recycling from perspective
of informal sector in its transition to enter as authorized waste
providers. Data used in the analysis are derived from multiple
strategies such as literature review, the Bogota’s recycling database,
focus group meetings, governmental reports, national laws and
regulations and specific interviews with key stakeholders. Results of
this study show as the main stakeholders of formal and informal
sector of waste management can identify the internal and internal
conditions of recycling in Bogotá. Several strategies were designed
based on the SWOTs determined, could be useful for Bogotá to
advance and promote recycling as a key strategy for integrated
sustainable waste management in the city.
Abstract: An innovative flooring underlayment was produced
and tested. The composite system is made of common OSB boards
and a layer of eco-friendly non-cement gypsum based material
(GeoGypTM). It was found that the shear bond between the two
materials is sufficient to secure the composite interaction between the
two. The very high compressive strength and relatively high tensile
strength of the non-cement based component together with its high
modulus of elasticity provides enough strength and stiffness for the
composite product to cover wider spacing between the joists. The
initial findings of this study indicate that with joist spacing as wide as
800 mm, the flooring system provides enough strength without
compromising the serviceability requirements of the building codes.
Abstract: This paper is concerned with knowledge representation
and extraction of fuzzy if-then rules using Interval Type-2
Context-based Fuzzy C-Means clustering (IT2-CFCM) with the aid of
fuzzy granulation. This proposed clustering algorithm is based on
information granulation in the form of IT2 based Fuzzy C-Means
(IT2-FCM) clustering and estimates the cluster centers by preserving
the homogeneity between the clustered patterns from the IT2 contexts
produced in the output space. Furthermore, we can obtain the
automatic knowledge representation in the design of Radial Basis
Function Networks (RBFN), Linguistic Model (LM), and Adaptive
Neuro-Fuzzy Networks (ANFN) from the numerical input-output data
pairs. We shall focus on a design of ANFN in this paper. The
experimental results on an estimation problem of energy performance
reveal that the proposed method showed a good knowledge
representation and performance in comparison with the previous
works.
Abstract: This paper presents a part of the project solving which
is dedicated to the identification of the hazardous waste with the most
critical production within the Czech Republic with the aim to study
and find the optimal composition of the cement matrix that will
ensure maximum content disposal of chosen hazardous waste. In the
first stage of project solving – which represents this paper – a specific
hazardous waste was chosen, its properties were identified and
suitable solidification agents were chosen. Consequently
solidification formulas and testing methodology was proposed.
Abstract: Moving into a new era of healthcare, new tools and
devices are developed to extend and improve health services, such as
remote patient monitoring and risk prevention. In this concept,
Internet of Things (IoT) and Cloud Computing present great
advantages by providing remote and efficient services, as well as
cooperation between patients, clinicians, researchers and other health
professionals. This paper focuses on patients suffering from bipolar
disorder, a brain disorder that belongs to a group of conditions
called affective disorders, which is characterized by great mood
swings. We exploit the advantages of Semantic Web and Cloud
Technologies to develop a patient monitoring system to support
clinicians. Based on intelligently filtering of evidence-knowledge and
individual-specific information we aim to provide treatment
notifications and recommended function tests at appropriate times or
concluding into alerts for serious mood changes and patient’s nonresponse
to treatment. We propose an architecture as the back-end
part of a cloud platform for IoT, intertwining intelligence devices
with patients’ daily routine and clinicians’ support.
Abstract: Reliability of long-term storage products is related to
the availability of the whole system, and the evaluation of storage life
is of great necessity. These products are usually highly reliable and
little failure information can be collected. In this paper, an analytical
method based on data from accelerated storage life test is proposed to
evaluate the reliability index of the long-term storage products. Firstly,
singularities are eliminated by data normalization and residual
analysis. Secondly, with the preprocessed data, the degradation path
model is built to obtain the pseudo life values. Then by life distribution
hypothesis, we can get the estimator of parameters in high stress levels
and verify failure mechanism consistency. Finally, the life distribution
under the normal stress level is extrapolated via the acceleration model
and evaluation of the actual average life is available. An application
example with the camera stabilization device is provided to illustrate
the methodology we proposed.
Abstract: Early diagnosis of infection like Hep-B virus in blood
is important for low cost medical treatment. For this purpose, it is
desirable to develop a point of care device which should be able to
detect trace quantities of the target molecule in blood. In this paper,
we report a nanoporous silicon oxide sensor which is capable of
detecting down to 1fM concentration of Hep-B surface antigen in
blood without the requirement of any centrifuge or pre-concentration.
This has been made possible by the presence of resonant peak in the
sensitivity characteristics. This peak is observed to be dependent only
on the concentration of the specific antigen and not on the interfering
species in blood serum. The occurrence of opposite impedance
change within the pores and at the bottom of the pore is responsible
for this effect. An electronic interface has also been designed to
provide a display of the virus concentration.
Abstract: Testability modeling is a commonly used method in
testability design and analysis of system. A dependency matrix will be
obtained from testability modeling, and we will give a quantitative
evaluation about fault detection and isolation.
Based on the dependency matrix, we can obtain the diagnosis tree.
The tree provides the procedures of the fault detection and isolation.
But the dependency matrix usually includes built-in test (BIT) and
manual test in fact. BIT runs the test automatically and is not limited
by the procedures. The method above cannot give a more efficient
diagnosis and use the advantages of the BIT.
A Comprehensive method of fault detection and isolation is
proposed. This method combines the advantages of the BIT and
Manual test by splitting the matrix. The result of the case study shows
that the method is effective.
Abstract: A cyclostationary Gaussian linearization method is
formulated for investigating the time average response of nonlinear
system under sinusoidal signal and white noise excitation. The
quantitative measure of cyclostationary mean, variance, spectrum of
mean amplitude, and mean power spectral density of noise are
analyzed. The qualitative response behavior of stochastic jump and
bifurcation are investigated. The validity of the present approach in
predicting the quantitative and qualitative statistical responses is
supported by utilizing Monte Carlo simulations. The present analysis
without imposing restrictive analytical conditions can be directly
derived by solving non-linear algebraic equations. The analytical
solution gives reliable quantitative and qualitative prediction of mean
and noise response for the Duffing system subjected to both sinusoidal
signal and white noise excitation.
Abstract: This study investigates the suitability of using plastic,
such as polyethylene terephthalate (PET), as a partial replacement of
natural coarse and fine aggregates (for example, brick chips and
natural sand) to produce lightweight concrete for load bearing
structural members. The plastic coarse aggregate (PCA) and plastic
fine aggregate (PFA) were produced from melted polyethylene
terephthalate (PET) bottles. Tests were conducted using three
different water–cement (w/c) ratios, such as 0.42, 0.48, and 0.57,
where PCA and PFA were used as 50% replacement of coarse and
fine aggregate respectively. Fresh and hardened properties of
concrete have been compared for natural aggregate concrete (NAC),
PCA concrete (PCC) and PFA concrete (PFC). The compressive
strength of concrete at 28 days varied with the water–cement ratio for
both the PCC and PFC. Between PCC and PFC, PFA concrete
showed the highest compressive strength (23.7 MPa) at 0.42 w/c ratio
and also the lowest compressive strength (13.7 MPa) at 0.57 w/c
ratio. Significant reduction in concrete density was mostly observed
for PCC samples, ranging between 1977–1924 kg/m³. With the
increase in water–cement ratio PCC achieved higher workability
compare to both NAC and PFC. It was found that both the PCA and
PFA contained concrete achieved the required compressive strength
to be used for structural purpose as partial replacement of the natural
aggregate; but to obtain the desired lower density as lightweight
concrete the PCA is most suited.
Abstract: The quality and condition of perishable products
delivered to the market and their subsequent selling prices are
directly affected by the care taken during harvesting and handling.
Mechanical injury, in fact, occurs at all stages, from pre-harvest
operations through post-harvest handling, packing and transport to
the market. The main implications of this damage are the reduction of
the product’s quality and economical losses related to the shelf life
diminution. For most perishable products, the shelf life is relatively
short and it is typically dictated by microbial growth related to the
application of dynamic and static loads during transportation. This
paper presents the correlation between vibration levels and
microbiological growth on strawberries and woodland strawberries
and detects the presence of volatile organic compounds (VOC) in
order to develop an intelligent logistic unit capable of monitoring
VOCs using a specific sensor system. Fresh fruits were exposed to
vibrations by means of a vibrating table in a temperature-controlled
environment. Microbiological analyses were conducted on samples,
taken at different positions along the column of the crates. The values
obtained were compared with control samples not exposed to
vibrations and the results show that different positions along the
column influence the development of bacteria, yeasts and filamentous
fungi.
Abstract: All the software engineering researches and best
industry practices aim at providing software products with high
degree of quality and functionality at low cost and less time. These
requirements are addressed by the Component Based Software
Engineering (CBSE) as well. CBSE, which deals with the software
construction by components’ assembly, is a revolutionary extension
of Software Engineering. CBSE must define and describe processes
to assure timely completion of high quality software systems that are
composed of a variety of pre built software components. Though
these features provide distinct and visible benefits in software design
and programming, they also raise some challenging problems. The
aim of this work is to summarize the pertinent issues and
considerations in CBSE to make an understanding in forms of
concepts and observations that may lead to development of newer
ways of dealing with the problems and challenges in CBSE.
Abstract: The purposes of this study are 1) to study the effects
of participatory error correction process and 2) to find out the
students’ satisfaction of such error correction process. This study is a
Quasi Experimental Research with single group, in which data is
collected 5 times preceding and following 4 experimental studies of
participatory error correction process including providing coded
indirect corrective feedback in the students’ texts with error treatment
activities. Samples include 52 2nd year English Major students,
Faculty of Humanities and Social Sciences, Suan Sunandha Rajabhat
University. Tool for experimental study includes the lesson plan of
the course; Reading and Writing English for Academic Purposes II,
and tools for data collection include 5 writing tests of short texts and
a questionnaire. Based on formative evaluation of the students’
writing ability prior to and after each of the 4 experiments, the
research findings disclose the students’ higher scores with statistical
difference at 0.00. Moreover, in terms of the effect size of such
process, it is found that for mean of the students’ scores prior to and
after the 4 experiments; d equals 0.6801, 0.5093, 0.5071, and 0.5296
respectively. It can be concluded that participatory error correction
process enables all of the students to learn equally well and there is
improvement in their ability to write short texts. Finally the students’
overall satisfaction of the participatory error correction process is in
high level (Mean = 4.39, S.D. = 0.76).