Abstract: Optical biosensors have become a powerful detection
and analysis tool for wide-ranging applications in biomedical research,
pharmaceuticals and environmental monitoring. This study carried out
the computational fluid dynamics (CFD)-based simulations to explore
the dispersion phenomenon in the micro channel of an optical
biosensor. The predicted time sequences of concentration contours
were utilized to better understand the dispersion development occurred
in different geometric shapes of micro channels. The simulation results
showed the surface concentrations at the sensing probe (with the best
performance of a grating coupler) in respect of time to appraise the
dispersion effect and therefore identify the design configurations
resulting in minimum dispersion.
Abstract: This paper addresses the design of hospital Intensive
Care Unit windows for the achievement of visual comfort and energy
savings. The aim was to identify the window size and shading system
configurations that could fulfill daylighting adequacy, avoid glare
and reduce energy consumption. The study focused on addressing the
effect of utilizing different shading systems in association with a
range of Window-to-Wall Ratios (WWR) in different orientations
under the desert clear-sky of Cairo, Egypt.
The results of this study demonstrated that solar penetration is a
critical concern affecting the design of ICU windows in desert
locations, as in Cairo, Egypt. Use of shading systems was found to be
essential in providing acceptable daylight performance and energy
saving. Careful positioning of the ICU window towards a proper
orientation can dramatically improve performance. It was observed
that ICU windows facing the north direction enjoyed the widest range
of successful window configuration possibilities at different WWRs.
ICU windows facing south enjoyed a reasonable number of
configuration options as well. By contrast, the ICU windows facing
the east orientation had a very limited number of options that provide
acceptable performance. These require additional local shading
measures at certain times due to glare incidence. Moreover, use of
horizontal sun breakers and solar screens to protect the ICU windows
proved to be more successful than the other alternatives in a wide
range of Window to Wall Ratios. By contrast, the use of light shelves
and vertical shading devices seemed questionable.
Abstract: Damage status of RC buildings is greatly influenced
by the characteristics of the imposed ground motion. Peak Ground
Acceleration and frequency contents are considered the main two
factors that affect ground motion characteristics; hence, affecting the
seismic response of RC structures and consequently their damage
state. A detailed investigation on the combined effects of these two
factors on damage assessment of RC buildings is carried out. Twenty
one earthquake records are analyzed and arranged into three groups,
according to their frequency contents. These records are used in an
investigation to define the expected damage state that would be
attained by RC buildings, if subjected to varying ground motion
characteristics. The damage assessment is conducted through
examining drift ratios and damage indices of the overall structure and
the significant structural components of RC building. Base and story
shear of RC building model, are also investigated, for cases when the
model is subjected to the chosen twenty one earthquake records.
Nonlinear dynamic analyses are performed on a 2-dimensional model
of a 12-story RC building.
Abstract: The aim of the current study was to develop and
validate a Response to Stressful Situations Scale (RSSS) for the
Portuguese population. This scale assesses the degree of stress
experienced in scenarios that can constitute positive, negative and
more neutral stressors, and also describes the physiological,
emotional and behavioral reactions to those events according to their
intensity. These scenarios include typical stressor scenarios relevant
to patients with schizophrenia, which are currently absent from most
scales, assessing specific risks that these stressors may bring on
subjects, which may prove useful in non-clinical and clinical
populations (i.e. Patients with mood or anxiety disorders,
schizophrenia). Results from Principal Components Analysis and
Confirmatory Factor Analysis of two adult samples from general
population allowed to confirm a three-factor model with good fit
indices: χ2 (144)= 370.211, p = 0.000; GFI = 0.928; CFI = 0.927; TLI =
0.914, RMSEA = 0.055, P(rmsea ≤0.005) = .096; PCFI = .781.
Further data analysis of the scale revealed that RSSS is an adequate
assessment tool of stress response in adults to be used in further
research and clinical settings, with good psychometric characteristics,
adequate divergent and convergent validity, good temporal stability
and high internal consistency.
Abstract: In this paper, we propose a system for preventing gas
risks through the use of wireless communication modules and
intelligent gas safety appliances. Our system configuration consists of
an automatic extinguishing system, detectors, a wall-pad, and a
microcomputer controlled micom gas meter to monitor gas flow and
pressure as well as the occurrence of earthquakes. The automatic fire
extinguishing system checks for both combustible gaseous leaks and
monitors the environmental temperature, while the detector array
measures smoke and CO gas concentrations. Depending on detected
conditions, the micom gas meter cuts off an inner valve and generates
a warning, the automatic fire-extinguishing system cuts off an external
valve and sprays extinguishing materials, or the sensors generate
signals and take further action when smoke or CO are detected.
Information on intelligent measures taken by the gas safety appliances
and sensors are transmitted to the wall-pad, which in turn relays this as
real time data to a server that can be monitored via an external network
(BcN) connection to a web or mobile application for the management
of gas safety. To validate this smart-home gas management system, we
field-tested its suitability for use in Korean apartments under several
scenarios.
Abstract: Waste load allocation (WLA) policies may use multiobjective
optimization methods to find the most appropriate and
sustainable solutions. These usually intend to simultaneously
minimize two criteria, total abatement costs (TC) and environmental
violations (EV). If other criteria, such as inequity, need for
minimization as well, it requires introducing more binary
optimizations through different scenarios. In order to reduce the
calculation steps, this study presents value index as an innovative
decision making approach. Since the value index contains both the
environmental violation and treatment costs, it can be maximized
simultaneously with the equity index. It implies that the definition of
different scenarios for environmental violations is no longer required.
Furthermore, the solution is not necessarily the point with minimized
total costs or environmental violations. This idea is testified for Haraz
River, in north of Iran. Here, the dissolved oxygen (DO) level of river
is simulated by Streeter-Phelps equation in MATLAB software. The
WLA is determined for fish farms using multi-objective particle
swarm optimization (MOPSO) in two scenarios. At first, the trade-off
curves of TC-EV and TC-Inequity are plotted separately as the
conventional approach. In the second, the Value-Equity curve is
derived. The comparative results show that the solutions are in a
similar range of inequity with lower total costs. This is due to the
freedom of environmental violation attained in value index. As a
result, the conventional approach can well be replaced by the value
index particularly for problems optimizing these objectives. This
reduces the process to achieve the best solutions and may find better
classification for scenario definition. It is also concluded that decision
makers are better to focus on value index and weighting its contents
to find the most sustainable alternatives based on their requirements.
Abstract: One of the most famous techniques which affect the
efficiency of a production line is the assembly line balancing (ALB)
technique. This paper examines the balancing effect of a whole
production line of a real auto glass manufacturer in three steps. In the
first step, processing time of each activity in the workstations is
generated according to a practical approach. In the second step, the
whole production process is simulated and the bottleneck stations
have been identified, and finally in the third step, several
improvement scenarios are generated to optimize the system
throughput, and the best one is proposed. The main contribution of
the current research is the proposed framework which combines two
famous approaches including Assembly Line Balancing and
Optimization via Simulation technique (OvS). The results show that
the proposed framework could be applied in practical environments,
easily.
Abstract: A simple adaptive voice activity detector (VAD) is
implemented using Gabor and gammatone atomic decomposition of
speech for high Gaussian noise environments. Matching pursuit is
used for atomic decomposition, and is shown to achieve optimal
speech detection capability at high data compression rates for low
signal to noise ratios. The most active dictionary elements found by
matching pursuit are used for the signal reconstruction so that the
algorithm adapts to the individual speakers dominant time-frequency
characteristics. Speech has a high peak to average ratio enabling
matching pursuit greedy heuristic of highest inner products to isolate
high energy speech components in high noise environments. Gabor
and gammatone atoms are both investigated with identical
logarithmically spaced center frequencies, and similar bandwidths.
The algorithm performs equally well for both Gabor and gammatone
atoms with no significant statistical differences. The algorithm
achieves 70% accuracy at a 0 dB SNR, 90% accuracy at a 5 dB SNR
and 98% accuracy at a 20dB SNR using 30d B SNR as a reference
for voice activity.
Abstract: The seismic risk mitigation from the perspective of
the old buildings stock is truly essential in Algerian urban areas,
particularly those located in seismic prone regions, such as Annaba
city, and which the old buildings present high levels of degradation
associated with no seismic strengthening and/or rehabilitation
concerns. In this sense, the present paper approaches the issue of the
seismic vulnerability assessment of old masonry building stocks
through the adaptation of a simplified methodology developed for a
European context area similar to that of Annaba city, Algeria.
Therefore, this method is used for the first level of seismic
vulnerability assessment of the masonry buildings stock of the old
city center of Annaba. This methodology is based on a vulnerability
index that is suitable for the evaluation of damage and for the
creation of large-scale loss scenarios. Over 380 buildings were
evaluated in accordance with the referred methodology and the
results obtained were then integrated into a Geographical Information
System (GIS) tool. Such results can be used by the Annaba city
council for supporting management decisions, based on a global view
of the site under analysis, which led to more accurate and faster
decisions for the risk mitigation strategies and rehabilitation plans.
Abstract: The present study was carried out to investigate the
effect of alloying elements and thermo-mechanical treatment (TMT)
i.e. hot rolling and forging with different reduction ratios on the
hardness (HV) and impact toughness (J) of heat-treated low alloy
steels. An understanding of the combined effect of TMT and alloying
elements and by measuring hardness, impact toughness, resulting
from different heat treatment following TMT of the low alloy steels,
it is possible to determine which conditions yielded optimum
mechanical properties and high strength to weight ratio.
Experimental Correlations between hot work reduction ratio,
hardness and impact toughness for thermo-mechanically heat treated
low alloy steels are analyzed quantitatively, and both regression and
mathematical hardness and impact toughness models are developed.
Abstract: In this contribution a structure for high level lateral vehicle tracking control based on the disturbance observer is presented. The structure is characterized by stationary compensating side forces disturbances and guaranteeing a cooperative behavior at the same time. Driver inputs are not compensated by the disturbance observer. Moreover the structure is especially useful as it robustly stabilizes the vehicle. Therefore the parameters are selected using the Parameter Space Approach. The implemented algorithms are tested in real world scenarios.
Abstract: A reliability-based methodology which uses structural demand hazard curves to consider the increment of the ductility demands of structures with tilting is proposed. The approach considers the effect of two orthogonal components of the ground motions as well as the influence of soil-structure interaction. The approach involves the calculation of ductility demand hazard curves for symmetric systems and, alternatively, for systems with different degrees of asymmetry. To get this objective, demand hazard curves corresponding to different global ductility demands of the systems are calculated. Next, Uniform Exceedance Rate Spectra (UERS) are developed for a specific mean annual rate of exceedance value. Ratios between UERS corresponding to asymmetric and to symmetric systems located in soft soil of the valley of Mexico are obtained. Results indicate that the ductility demands corresponding to tilted structures may be several times higher than those corresponding to symmetric structures, depending on several factors such as tilting angle and vibration period of structure and soil.
Abstract: Moving into a new era of healthcare, new tools and
devices are developed to extend and improve health services, such as
remote patient monitoring and risk prevention. In this concept,
Internet of Things (IoT) and Cloud Computing present great
advantages by providing remote and efficient services, as well as
cooperation between patients, clinicians, researchers and other health
professionals. This paper focuses on patients suffering from bipolar
disorder, a brain disorder that belongs to a group of conditions
called affective disorders, which is characterized by great mood
swings. We exploit the advantages of Semantic Web and Cloud
Technologies to develop a patient monitoring system to support
clinicians. Based on intelligently filtering of evidence-knowledge and
individual-specific information we aim to provide treatment
notifications and recommended function tests at appropriate times or
concluding into alerts for serious mood changes and patient’s nonresponse
to treatment. We propose an architecture as the back-end
part of a cloud platform for IoT, intertwining intelligence devices
with patients’ daily routine and clinicians’ support.
Abstract: This study investigates the suitability of using plastic,
such as polyethylene terephthalate (PET), as a partial replacement of
natural coarse and fine aggregates (for example, brick chips and
natural sand) to produce lightweight concrete for load bearing
structural members. The plastic coarse aggregate (PCA) and plastic
fine aggregate (PFA) were produced from melted polyethylene
terephthalate (PET) bottles. Tests were conducted using three
different water–cement (w/c) ratios, such as 0.42, 0.48, and 0.57,
where PCA and PFA were used as 50% replacement of coarse and
fine aggregate respectively. Fresh and hardened properties of
concrete have been compared for natural aggregate concrete (NAC),
PCA concrete (PCC) and PFA concrete (PFC). The compressive
strength of concrete at 28 days varied with the water–cement ratio for
both the PCC and PFC. Between PCC and PFC, PFA concrete
showed the highest compressive strength (23.7 MPa) at 0.42 w/c ratio
and also the lowest compressive strength (13.7 MPa) at 0.57 w/c
ratio. Significant reduction in concrete density was mostly observed
for PCC samples, ranging between 1977–1924 kg/m³. With the
increase in water–cement ratio PCC achieved higher workability
compare to both NAC and PFC. It was found that both the PCA and
PFA contained concrete achieved the required compressive strength
to be used for structural purpose as partial replacement of the natural
aggregate; but to obtain the desired lower density as lightweight
concrete the PCA is most suited.
Abstract: The aim of this paper is to present the optimization
methodology developed in the frame of a Coastal Transport
Information System. The system will be used for the effective design
of coastal transportation lines and incorporates subsystems that
implement models, tools and techniques that may support the design
of improved networks. The role of the optimization and decision
subsystem is to provide the user with better and optimal scenarios
that will best fulfill any constrains, goals or requirements posed. The
complexity of the problem and the large number of parameters and
objectives involved led to the adoption of an evolutionary method
(Genetic Algorithms). The problem model and the subsystem
structure are presented in detail, and, its support for simulation is also
discussed.
Abstract: Increasing prevalence of childhood obesity has
increased the interest in early and late indicators of gaining weight.
Cell blood counts may be indicators of pro-inflammatory states. The
aim was to evaluate associations of hematological parameters,
including hematocrit (HTC), hemoglobin, blood cell counts and their
indices with the degree of obesity in pediatric population. A total of
249; -139 morbidly obese (MO), 82 healthy normal weight (NW) and
28 overweight (OW) children were included into the scope of the
study. WHO BMI-for age percentiles were used to form age- and sexmatched
groups. Informed consent forms and the Ethics Committee
approval were obtained. Anthropometric measurements were
performed. Hematological parameters were determined. Statistical
analyses were performed using SPSS. The degree for statistical
significance was p≤0.05. Significant differences (p=0.000) between
waist-to-hip ratios and head-to- neck ratios (hnrs) of MO and NW
children were detected. A significant difference between hnrs of OW
and MO children (p=0.000) was observed. Red cell distribution width
(RDW) was higher in OW children than NW group (p=0.030). Such
finding couldn’t be detected between MO and NW groups. Increased
RDW was prominent in OW children. The decrease in mean
corpuscular hemoglobin concentration (MCHC) values in MO
children was sharper than the values in OW children (p=0.006 vs
p=0.042) compared to those in NW group. Statistically higher HTC
levels were observed between MO-NW (p=0.014), but none between
OW-NW. Though the cause-effect relationship between obesity and
erythrocyte indices still needs further investigation, alterations in
RDW, HTC, MCHC during obesity may be of significance in the
early life.
Abstract: Phelipanche ramosa is the most damaging obligate
flowering parasitic weed on wide species of cultivated plants. The
semi-arid regions of the world are considered the main centers of this
parasitic plant that causes heavy infestation. This is due to its
production of high numbers of seeds (up to 200,000) that remain
viable for extended periods (up to 20 years). In this study, 13
treatments for the control of Phelipanche were carried out, which
included agronomic, chemical, and biological treatments and the use
of resistant plant methods. In 2014, a trial was performed at the
Department of Agriculture, Food and Environment, University of
Foggia (southern Italy), on processing tomato (cv ‘Docet’) grown in
pots filled with soil taken from a field that was heavily infested by P.
ramosa). The tomato seedlings were transplanted on May 8, 2014,
into a sandy-clay soil (USDA). A randomized block design with 3
replicates (pots) was adopted. During the growing cycle of the
tomato, at 70, 75, 81 and 88 days after transplantation, the number of
P. ramosa shoots emerged in each pot was determined. The tomato
fruit were harvested on August 8, 2014, and the quantitative and
qualitative parameters were determined. All of the data were
subjected to analysis of variance (ANOVA) using the JMP software
(SAS Institute Inc. Cary, NC, USA), and for comparisons of means
(Tukey's tests). The data show that each treatment studied did not
provide complete control against P. ramosa. However, the virulence
of the attacks was mitigated by some of the treatments tried: radicon
biostimulant, compost activated with Fusarium, mineral fertilizer
nitrogen, sulfur, enzone, and the resistant tomato genotype. It is
assumed that these effects can be improved by combining some of
these treatments with each other, especially for a gradual and
continuing reduction of the “seed bank” of the parasite in the soil.
Abstract: The construction industry has been demonstrating
increased growth and importance in Brazil’s national economic
development. This study aims to evaluate the financial performance
of the leading companies in the construction sector in Brazil in the
period from 2009 to 2012. An analysis is made of the capital
structure, liquidity, and profitability of the six largest companies in
the construction sector in Brazil: Brookfield, Cyrela, Gafisa, MRV,
PDG and Rossi. The results are then compared with standard industry
ratios. It was found that among the companies analyzed, MRV and
Cyrela showed the best relative performance in the period under
consideration.
Abstract: Co-crystal is believed to improve the solubility and
dissolution rates and thus, enhanced the bioavailability of poor water
soluble drugs particularly during the oral route of administration.
With the existing of poorly soluble drugs in pharmaceutical industry,
the screening of co-crystal formation using carbamazepine (CBZ) as
a model drug compound with dicarboxylic acids co-crystal formers
(CCF) namely fumaric (FA) and succinic (SA) acids in ethanol has
been studied. The co-crystal formations were studied by varying the
mol ratio values of CCF to CBZ to access the effect of CCF
concentration on the formation of the co-crystal. Solvent evaporation,
slurry and cooling crystallization which representing the solution
based method co-crystal screening were used. Based on the
differential scanning calorimetry (DSC) analysis, the melting point of
CBZ-SA in different ratio was in the range between 188oC-189oC.
For CBZ-FA form A and CBZ-FA form B the melting point in
different ratio were in the range of 174oC-175oC and 185oC-186oC
respectively. The product crystal from the screening was also
characterized using X-ray powder diffraction (XRPD). The XRPD
pattern profile analysis has shown that the CBZ co-crystals with FA
and SA were successfully formed for all ratios studied. The findings
revealed that CBZ-FA co-crystal were formed in two different
polymorphs. It was found that CBZ-FA form A and form B were
formed from evaporation and slurry crystallization methods
respectively. On the other hand, in cooling crystallization method,
CBZ-FA form A was formed at lower mol ratio of CCF to CBZ and
vice versa. This study disclosed that different methods and mol ratios
during the co-crystal screening can affect the outcome of co-crystal
produced such as polymorphic forms of co-crystal and thereof. Thus,
it was suggested that careful attentions is needed during the screening
since the co-crystal formation is currently one of the promising
approach to be considered in research and development for
pharmaceutical industry to improve the poorly soluble drugs.
Abstract: The feedbacks obtained regarding the sense of
presence from pilot users operating a Mobile Robotic presence
(MRP) system to visit a simulated museum are reported in this paper.
The aim is to investigate how much the perception of system’s
usefulness and ease of use is affected by operators’ sense of social
telepresence (presence) in the remote location. Therefore, scenarios
of visiting a museum are simulated and the user operators are
supposed to perform some regular tasks inside the remote
environment including interaction with local users, navigation and
visiting the artworks. Participants were divided into two groups,
those who had previous experience of operation and interaction with
a MRP system and those who never had experience. Based on the
results, both groups provided different feedbacks. Moreover, there
was a significant association between user’s sense of presence and
their perception of system usefulness and ease of use.