Abstract: A rare phenomenon of SDS-induced activation of a latent protease activity associated with the purified silkworm excretory red fluorescent protein (SE-RFP) was noticed. SE-RFP aliquots incubated with SDS for different time intervals indicated that the protein undergoes an obligatory breakdown into a number of subunits which exhibit autoproteolytic (acting upon themselves) and/or heteroproteolytic (acting on other proteins) activities. A strong serine protease activity of SE-RFP subunits on Bombyx mori nucleopolyhedrovirus (BmNPV) polyhedral protein was detected by zymography technique. A complete inhibition of BmNPV infection to silkworms was observed by the oral administration assay of the SE-RFP. Here, it is proposed that the SE-RFP prevents the initial infection of BmNPV to silkworms by obliterating the polyhedral protein. This is the first report on a silkworm red fluorescent protein that exhibits a protease activity on exposure to SDS. The present studies would help in understanding the antiviral mechanism of silkworm red fluorescent proteins.
Abstract: Simultaneous determination of multicomponents of phenol, resorcinol and catechol with a chemometric technique a PCranking artificial neural network (PCranking-ANN) algorithm is reported in this study. Based on the data correlation coefficient method, 3 representative PCs are selected from the scores of original UV spectral data (35 PCs) as the original input patterns for ANN to build a neural network model. The results obtained by iterating 8000 .The RMSEP for phenol, resorcinol and catechol with PCranking- ANN were 0.6680, 0.0766 and 0.1033, respectively. Calibration matrices were 0.50-21.0, 0.50-15.1 and 0.50-20.0 μg ml-1 for phenol, resorcinol and catechol, respectively. The proposed method was successfully applied for the determination of phenol, resorcinol and catechol in synthetic and water samples.
Abstract: The explosion of interest in online gaming and
virtual worlds is leading many universities to investigate
possible educational applications of the new environments.
In this paper we explore the possibilities of 3D online worlds
for teacher education, particularly the field experience
component. Drawing upon two pedagogical examples, we
suggest that virtual simulations may, with certain limitations,
create safe spaces that allow preservice teachers to adopt
alternate identities and interact safely with the “other." In so
doing they may become aware of the constructed nature of
social categories and gain the essential pedagogical skill of
perspective-taking. We suggest that, ultimately, the ability to
be the principal creators of themselves in virtual environments
can increase their ability to do the same in the real world.
Abstract: A generic and extendible Multi-Agent Data Mining
(MADM) framework, MADMF (the Multi-Agent Data Mining
Framework) is described. The central feature of the framework is that
it avoids the use of agreed meta-language formats by supporting a
framework of wrappers.
The advantage offered is that the framework is easily extendible,
so that further data agents and mining agents can simply be added to
the framework. A demonstration MADMF framework is currently
available. The paper includes details of the MADMF architecture and
the wrapper principle incorporated into it. A full description and
evaluation of the framework-s operation is provided by considering
two MADM scenarios.
Abstract: Climate change and environmental pressures are
major international issues nowadays. It is time when governments,
businesses and consumers have to respond through more
environmentally friendly and aware practices, products and policies.
This is the prime time to develop alternative sustainable construction
materials, reduce greenhouse gas emissions, save energy, look to
renewable energy sources and recycled materials, and reduce waste.
The utilization of waste materials (slag, fly ash, glass beads, plastic
and so on) in concrete manufacturing is significant due to its
engineering, financial, environmental and ecological benefits. Thus,
utilization of waste materials in concrete production is very much
helpful to reach the goal of the sustainable construction. Therefore,
this study intends to use glass beads in concrete production.
The paper reports on the performance of 9 different concrete
mixes containing different ratios of glass crushed to 5 mm - 20 mm
maximum size and glass marble of 20 mm size as coarse aggregate.
Ordinary Portland cement type 1 and fine sand less than 0.5 mm were
used to produce standard concrete cylinders. Compressive strength
tests were carried out on concrete specimens at various ages. Test
results indicated that the mix having the balanced ratio of glass beads
and round marbles possess maximum compressive strength which is
3889 psi, as glass beads perform better in bond formation but have
lower strength, on the other hand marbles are strong in themselves
but not good in bonding. These mixes were prepared following a
specific W/C and aggregate ratio; more strength can be expected to
achieve from different W/C, aggregate ratios, adding admixtures like
strength increasing agents, ASR inhibitor agents etc.
Abstract: In this article, some methods are mentioned for developing the theatrical language by giving information of “theatrical language" since the arising of the language in obsolete terms, and today, and also by examining the problems. Being able to talk meaningfully in the theater stage is a skillful art. Maybe, to be able to convey the idea of the poet, his/her world outlook and his/her feelings from the bottom of the heart as such, also conveying the speech norms without breaking them to the ear of audience in a fascinating way in adverse of a repellent way is the most difficult one. Because of this, “the word is the mirror of the idea". The importance of the theatrical language should not be perceived as only a post, it is “as the yarn that the culture carpet is weaved from". Thereby, it is a tool which transposes our culture and our life style from generation to generation. At the time of creativeness, the “word" comes out from the poet, “the word and feeling" art comes out from the actor. If it was not so, the audience could read the texts of the work himself/herself instead of going to the theater in order to see the performance. The fundamental works by the Turkish, Kazakh and English scientists have been taken as a basis for the research done.
Abstract: In this paper we propose a new content-weighted
method for full reference (FR) video quality control using a region of
interest (ROI) and wherein two-component weighted metrics for Deaf
People Video Communication. In our approach, an image is
partitioned into region of interest and into region "dry-as-dust", then
region of interest is partitioned into two parts: edges and background
(smooth regions), while the another methods (metrics) combined and
weighted three or more parts as edges, edges errors, texture, smooth
regions, blur, block distance etc. as we proposed. Using another idea
that different image regions from deaf people video communication
have different perceptual significance relative to quality. Intensity
edges certainly contain considerable image information and are
perceptually significant.
Abstract: This paper deals with an adaptive multiuser detector for direct sequence code division multiple-access (DS-CDMA) systems. A modified receiver, precombinig LMMSE is considered under time varying channel environment. Detector updating is performed with two criterions, mean square estimation (MSE) and MOE optimization technique. The adaptive implementation issues of these two schemes are quite different. MSE criterion updates the filter weights by minimizing error between data vector and adaptive vector. MOE criterion together with canonical representation of the detector results in a constrained optimization problem. Even though the canonical representation is very complicated under time varying channels, it is analyzed with assumption of average power profile of multipath replicas of user of interest. The performance of both schemes is studied for practical SNR conditions. Results show that for poor SNR, MSE precombining LMMSE is better than the blind precombining LMMSE but for greater SNR, MOE scheme outperforms with better result.
Abstract: With the advent of emerging personal computing paradigms such as ubiquitous and mobile computing, Web contents are becoming accessible from a wide range of mobile devices. Since these devices do not have the same rendering capabilities, Web contents need to be adapted for transparent access from a variety of client agents. Such content adaptation results in better rendering and faster delivery to the client device. Nevertheless, Web content adaptation sets new challenges for semantic markup. This paper presents an advanced components platform, called MorfeoSMC, enabling the development of mobility applications and services according to a channel model based on Services Oriented Architecture (SOA) principles. It then goes on to describe the potential for integration with the Semantic Web through a novel framework of external semantic annotation of mobile Web contents. The role of semantic annotation in this framework is to describe the contents of individual documents themselves, assuring the preservation of the semantics during the process of adapting content rendering, as well as to exploit these semantic annotations in a novel user profile-aware content adaptation process. Semantic Web content adaptation is a way of adding value to and facilitates repurposing of Web contents (enhanced browsing, Web Services location and access, etc).
Abstract: Repeated observation of a given area over time yields
potential for many forms of change detection analysis. These
repeated observations are confounded in terms of radiometric
consistency due to changes in sensor calibration over time,
differences in illumination, observation angles and variation in
atmospheric effects.
This paper demonstrates applicability of an empirical relative
radiometric normalization method to a set of multitemporal cloudy
images acquired by Resourcesat1 LISS III sensor. Objective of this
study is to detect and remove cloud cover and normalize an image
radiometrically. Cloud detection is achieved by using Average
Brightness Threshold (ABT) algorithm. The detected cloud is
removed and replaced with data from another images of the same
area. After cloud removal, the proposed normalization method is
applied to reduce the radiometric influence caused by non surface
factors. This process identifies landscape elements whose reflectance
values are nearly constant over time, i.e. the subset of non-changing
pixels are identified using frequency based correlation technique. The
quality of radiometric normalization is statistically assessed by R2
value and mean square error (MSE) between each pair of analogous
band.
Abstract: In this paper an extensive verification of the extraction
method (published earlier) that consistently accounts for self-heating
and Early effect to accurately extract both base and thermal resistance
of bipolar junction transistors is presented. The method verification is
demonstrated on advanced RF SiGe HBTs were the extracted results
for the thermal resistance are compared with those from another
published method that ignores the effect of Early effect on internal
base-emitter voltage and the extracted results of the base resistance
are compared with those determined from noise measurements. A
self-consistency of our method in the extracted base resistance and
thermal resistance using compact model simulation results is also
carried out in order to study the level of accuracy of the method.
Abstract: This paper discusses on the use of Spline Interpolation
and Mean Square Error (MSE) as tools to process data acquired from
the developed simulator that shall replicate sea bed logging environment.
Sea bed logging (SBL) is a new technique that uses marine
controlled source electromagnetic (CSEM) sounding technique and is
proven to be very successful in detecting and characterizing hydrocarbon
reservoirs in deep water area by using resistivity contrasts. It uses
very low frequency of 0.1Hz to 10 Hz to obtain greater wavelength.
In this work the in house built simulator was used and was provided
with predefined parameters and the transmitted frequency was varied
for sediment thickness of 1000m to 4000m for environment with and
without hydrocarbon. From series of simulations, synthetics data were
generated. These data were interpolated using Spline interpolation
technique (degree of three) and mean square error (MSE) were
calculated between original data and interpolated data. Comparisons
were made by studying the trends and relationship between frequency
and sediment thickness based on the MSE calculated. It was found
that the MSE was on increasing trends in the set up that has the
presence of hydrocarbon in the setting than the one without. The MSE
was also on decreasing trends as sediment thickness was increased
and with higher transmitted frequency.
Abstract: The Petri net tool INA is a well known tool by the
Petri net community. However, it lacks a graphical environment to
cerate and analyse INA models. Building a modelling tool for the
design and analysis from scratch (for INA tool for example) is
generally a prohibitive task. Meta-Modelling approach is useful to
deal with such problems since it allows the modelling of the
formalisms themselves. In this paper, we propose an approach based
on the combined use of Meta-modelling and Graph Grammars to
automatically generate a visual modelling tool for INA for analysis
purposes. In our approach, the UML Class diagram formalism is
used to define a meta-model of INA models. The meta-modelling
tool ATOM3 is used to generate a visual modelling tool according to
the proposed INA meta-model. We have also proposed a graph
grammar to automatically generate INA description of the
graphically specified Petri net models. This allows the user to avoid
the errors when this description is done manually. Then the INA tool
is used to perform the simulation and the analysis of the resulted INA
description. Our environment is illustrated through an example.
Abstract: Measurement of the quality of image compression is important for image processing application. In this paper, we propose an objective image quality assessment to measure the quality of gray scale compressed image, which is correlation well with subjective quality measurement (MOS) and least time taken. The new objective image quality measurement is developed from a few fundamental of objective measurements to evaluate the compressed image quality based on JPEG and JPEG2000. The reliability between each fundamental objective measurement and subjective measurement (MOS) is found. From the experimental results, we found that the Maximum Difference measurement (MD) and a new proposed measurement, Structural Content Laplacian Mean Square Error (SCLMSE), are the suitable measurements that can be used to evaluate the quality of JPEG200 and JPEG compressed image, respectively. In addition, MD and SCLMSE measurements are scaled to make them equivalent to MOS, given the rate of compressed image quality from 1 to 5 (unacceptable to excellent quality).
Abstract: Yeast cells live in a constantly changing environment that requires the continuous adaptation of their genomic program in order to sustain their homeostasis, survive and proliferate. Due to the advancement of high throughput technologies, there is currently a large amount of data such as gene expression, gene deletion and protein-protein interactions for S. Cerevisiae under various environmental conditions. Mining these datasets requires efficient computational methods capable of integrating different types of data, identifying inter-relations between different components and inferring functional groups or 'modules' that shape intracellular processes. This study uses computational methods to delineate some of the mechanisms used by yeast cells to respond to environmental changes. The GRAM algorithm is first used to integrate gene expression data and ChIP-chip data in order to find modules of coexpressed and co-regulated genes as well as the transcription factors (TFs) that regulate these modules. Since transcription factors are themselves transcriptionally regulated, a three-layer regulatory cascade consisting of the TF-regulators, the TFs and the regulated modules is subsequently considered. This three-layer cascade is then modeled quantitatively using artificial neural networks (ANNs) where the input layer corresponds to the expression of the up-stream transcription factors (TF-regulators) and the output layer corresponds to the expression of genes within each module. This work shows that (a) the expression of at least 33 genes over time and for different stress conditions is well predicted by the expression of the top layer transcription factors, including cases in which the effect of up-stream regulators is shifted in time and (b) identifies at least 6 novel regulatory interactions that were not previously associated with stress-induced changes in gene expression. These findings suggest that the combination of gene expression and protein-DNA interaction data with artificial neural networks can successfully model biological pathways and capture quantitative dependencies between distant regulators and downstream genes.
Abstract: Starting from a biologically inspired framework, Gabor filters were built up from retinal filters via LMSE algorithms. Asubset of retinal filter kernels was chosen to form a particular Gabor filter by using a weighted sum. One-dimensional optimization approaches were shown to be inappropriate for the problem. All model parameters were fixed with biological or image processing constraints. Detailed analysis of the optimization procedure led to the introduction of a minimization constraint. Finally, quantization of weighting factors was investigated. This resulted in an optimized cascaded structure of a Gabor filter bank implementation with lower computational cost.
Abstract: The ability of information systems to operate in conjunction with each other encompassing communication protocols, hardware, software, application, and data compatibility layers. There has been considerable work in industry on the development of component interoperability models, such as CORBA, (D)COM and JavaBeans. These models are intended to reduce the complexity of software development and to facilitate reuse of off-the-shelf components. The focus of these models is syntactic interface specification, component packaging, inter-component communications, and bindings to a runtime environment. What these models lack is a consideration of architectural concerns – specifying systems of communicating components, explicitly representing loci of component interaction, and exploiting architectural styles that provide well-understood global design solutions. The development of complex business applications is now focused on an assembly of components available on a local area network or on the net. These components must be localized and identified in terms of available services and communication protocol before any request. The first part of the article introduces the base concepts of components and middleware while the following sections describe the different up-todate models of communication and interaction and the last section shows how different models can communicate among themselves.
Abstract: Previous studies have shown that there are arguments
regarding the reliability and validity of the Ashworth and Modified
Ashworth Scale towards evaluating patients diagnosed with upper
limb disorders. These evaluations depended on the raters’ experiences.
This initiated us to develop an upper limb disorder part-task trainer
that is able to simulate consistent upper limb disorders, such as
spasticity and rigidity signs, based on the Modified Ashworth Scale to
improve the variability occurring between raters and intra-raters
themselves. By providing consistent signs, novice therapists would be
able to increase training frequency and exposure towards various
levels of signs. A total of 22 physiotherapists and occupational
therapists participated in the study. The majority of the therapists
agreed that with current therapy education, they still face problems
with inter-raters and intra-raters variability (strongly agree 54%; n =
12/22, agree 27%; n = 6/22) in evaluating patients’ conditions. The
therapists strongly agreed (72%; n = 16/22) that therapy trainees
needed to increase their frequency of training; therefore believe that
our initiative to develop an upper limb disorder training tool will help
in improving the clinical education field (strongly agree and agree
63%; n = 14/22).
Abstract: This paper deals with wireless relay communication
systems in which multiple sources transmit information to the
destination node by the help of multiple relays. We consider a
signal forwarding technique based on the minimum mean-square
error (MMSE) approach with multiple antennas for each relay. A
source-relay-destination joint design strategy is proposed with power
constraints at the destination and the source nodes. Simulation results
confirm that the proposed joint design method improves the average
MSE performance compared with that of conventional MMSE relaying
schemes.
Abstract: The purpose of this research was to demonstrate
prevalence of post-exposure preventive measures (PEP) after needlestick
injuries and its relationship with locus of control beliefs in a
sample of medical students. In this cross-sectional study, 300 medical
students with history of having experienced needle stick injuries
(NSI) for at least once filled in a questionnaire to determine if they
perceived themselves to be responsible and effective in preventing
blood born infections after NSI. About 38% of students did not seek
any professional consult or PEP after NSI due to lack of enough time
or access, anxiety about tests results, belief in uselessness of followup
and not being able to change destiny. These 114 students were not
different from others regarding their scores on NSI specific scale of
locus of health control. Thus, the potentiality of NSI locus of control
beliefs in predicting PEP was not seen in this study.