Abstract: Reverse engineering of full-genomic interaction networks based on compendia of expression data has been successfully applied for a number of model organisms. This study adapts these approaches for an important non-model organism: The major human fungal pathogen Candida albicans. During the infection process, the pathogen can adapt to a wide range of environmental niches and reversibly changes its growth form. Given the importance of these processes, it is important to know how they are regulated. This study presents a reverse engineering strategy able to infer fullgenomic interaction networks for C. albicans based on a linear regression, utilizing the sparseness criterion (LASSO). To overcome the limited amount of expression data and small number of known interactions, we utilize different prior-knowledge sources guiding the network inference to a knowledge driven solution. Since, no database of known interactions for C. albicans exists, we use a textmining system which utilizes full-text research papers to identify known regulatory interactions. By comparing with these known regulatory interactions, we find an optimal value for global modelling parameters weighting the influence of the sparseness criterion and the prior-knowledge. Furthermore, we show that soft integration of prior-knowledge additionally improves the performance. Finally, we compare the performance of our approach to state of the art network inference approaches.
Abstract: Manganese steel (Hadfield) is one of the important
alloys in industry due to its special properties. High work hardening
ability with appropriate toughness and ductility are the properties that
caused this alloy to be used in wear resistance parts and in high
strength condition. Heat treatment is the main process through which
the desired mechanical properties and microstructures are obtained in
Hadfield steel. In this study various heat treatment cycles, differing in
austenising temperature, time and quenching solution are applied. For
this purpose, the same samples of manganese steel was heat treated in
9 different cycles, and then the mechanical properties and
microstructures were investigated. Based on the results of the study,
the optimum heat treatment cycle was obtained.
Abstract: In the current economy of increasing global
competition, many organizations are attempting to use knowledge as
one of the means to gain sustainable competitive advantage. Besides
large organizations, the success of SMEs can be linked to how well
they manage their knowledge. Despite the profusion of research
about knowledge management within large organizations, fewer
studies tried to analyze KM in SMEs.
This research proposes a new framework showing the determinant
role of organizational dimensions onto KM approaches. The paper
and its propositions are based on a literature review and analysis.
In this research, personalization versus codification,
individualization versus institutionalization and IT-based versus non
IT-based are highlighted as three distinct dimensions of knowledge
management approaches.
The study contributes to research by providing a more nuanced
classification of KM approaches and provides guidance to managers
about the types of KM approaches that should be adopted based on
the size, geographical dispersion and task nature of SMEs.
To the author-s knowledge, the paper is the first of its kind to
examine if there are suitable configurations of KM approaches for
SMEs with different dimensions. It gives valuable information, which
hopefully will help SME sector to accomplish KM.
Abstract: Amazing development of the information technology,
communications and internet expansion as well as the requirements
of the city managers to new ideas to run the city and higher
participation of the citizens encourage us to complete the electronic
city as soon as possible. The foundations of this electronic city are in
information technology. People-s participation in metropolitan
management is a crucial topic. Information technology does not
impede this matter. It can ameliorate populace-s participation and
better interactions between the citizens and the city managers.
Citizens can proffer their ideas, beliefs and votes through digital
mass media based upon the internet and computerization plexuses on
the topical matters to receive appropriate replies and services. They
can participate in urban projects by becoming cognizant of the city
views. The most significant challenges are as follows: information
and communicative management, altering citizens- views, as well as
legal and office documents
Electronic city obstacles have been identified in this research. The
required data were forgathered through questionnaires to identify the
barriers from a statistical community comprising specialists and
practitioners of the ministry of information technology and
communication, the municipality information technology
organization.
The conclusions demonstrate that the prioritized electronic city
application barriers in Iran are as follows:
The support quandaries (non-financial ones), behavioral, cultural
and educational plights, the security, legal and license predicaments,
the hardware, orismological and infrastructural curbs, the software
and fiscal problems.
Abstract: This article proposes a new methodology to be used by SMEs (Small and Medium enterprises) to characterize their performance in quality, highlighting weaknesses and area for improvement. The methodology aims to identify the principal causes of quality problems and help to prioritize improvement initiatives. This is a self-assessment methodology that intends to be easy to implement by companies with low maturity level in quality. The methodology is organized in six different steps which includes gathering information about predetermined processes and subprocesses of quality management, defined based on the well-known Juran-s trilogy for quality management (Quality planning, quality control and quality improvement) and, predetermined results categories, defined based on quality concept. A set of tools for data collecting and analysis, such as interviews, flowcharts, process analysis diagrams and Failure Mode and effects Analysis (FMEA) are used. The article also presents the conclusions obtained in the application of the methodology in two cases studies.
Abstract: Austenite and Martensite indicate the phases of solids undergoing phase transformation which we usually associate with materials and not with living organisms. This article provides an overview of bacterial proteins and structures that are undergoing phase transformation and suggests its probable effect on mechanical behavior. The context is mainly within the role of phase transformations occurring in the flagellum of bacteria. The current knowledge of molecular mechanism leading to phase variation in living organisms is reviewed. Since in bacteria, each flagellum is driven by a separate motor, similarity to a Differential drive in case of four-wheeled vehicles is suggested. It also suggests the application of the mechanism in which bacteria changes its direction of movement to facilitate single point turning of a multi-wheeled vehicle. Finally, examples are presented to illustrate that the motion due to phase transformation of flagella in bacteria can start a whole new research on motion mechanisms.
Abstract: The distinction among urban, periurban and rural areas represents a classical example of uncertainty in land classification. Satellite images, geostatistical analysis and all kinds of spatial data are very useful in urban sprawl studies, but it is important to define precise rules in combining great amounts of data to build complex knowledge about territory. Rough Set theory may be a useful method to employ in this field. It represents a different mathematical approach to uncertainty by capturing the indiscernibility. Two different phenomena can be indiscernible in some contexts and classified in the same way when combining available information about them. This approach has been applied in a case of study, comparing the results achieved with both Map Algebra technique and Spatial Rough Set. The study case area, Potenza Province, is particularly suitable for the application of this theory, because it includes 100 municipalities with different number of inhabitants and morphologic features.
Abstract: While financial institutions have faced difficulties
over the years for a multitude of reasons, the major cause of serious
banking problems continues to be directly related to lax credit
standards for borrowers and counterparties, poor portfolio risk
management, or a lack of attention to changes in economic or other
circumstances that can lead to a deterioration in the credit standing of
a bank's counterparties. Credit risk is most simply defined as the
potential that a bank borrower or counterparty will fail to meet its
obligations in accordance with agreed terms. The goal of credit risk
management is to maximize a bank's risk-adjusted rate of return by
maintaining credit risk exposure within acceptable parameters. Banks
need to manage the credit risk inherent in the entire portfolio as well
as the risk in individual credits or transactions. Banks should also
consider the relationships between credit risk and other risks. The
effective management of credit risk is a critical component of a
comprehensive approach to risk management and essential to the
long-term success of any banking organization. In this research we
also study the relationship between credit risk indices and borrower-s
timely payback in Karafarin bank.
Abstract: This paper adopts a notion of expectation-perception
gap of systems users as information systems (IS) failure. Problems
leading to the expectation-perception gap are identified and modelled
as five interrelated discrepancies or gaps throughout the process of
information systems development (ISD). It describes an empirical
study on how systems developers and users perceive the size of each
gap and the extent to which each problematic issue contributes to the
gap. The key to achieving success in ISD is to keep the expectationperception
gap closed by closing all 5 pertaining gaps. The gap model
suggests that most factors in IS failure are related to organizational,
cognitive and social aspects of information systems design.
Organization requirement analysis, being the weakest link of IS
development, is particularly worthy of investigation.
Abstract: The purpose of the experiments described in this article was the comparison of integrated fixed film activated sludge (IFAS) and activated sludge (AS) system. The IFAS applied system consists of the cigarette filter rods (wasted filter in tobacco factories) as a biofilm carrier. The comparison with activated sludge was performed by two parallel treatment lines. Organic substance, ammonia and TP removal was investigated over four month period. Synthetic wastewater was prepared with ordinary tap water and glucose as the main sources of carbon and energy, plus balanced macro and micro nutrients. COD removal percentages of 94.55%, and 81.62% were achieved for IFAS and activated sludge system, respectively. Also, ammonia concentration significantly decreased by increasing the HRT in both systems. The average ammonia removal of 97.40 % and 96.34% were achieved for IFAS and activated sludge system, respectively. The removal efficiency of total phosphorus (TP-P) was 60.64%, higher than AS process by 56.63% respectively.
Abstract: Biological data has several characteristics that strongly differentiate it from typical business data. It is much more complex, usually large in size, and continuously changes. Until recently business data has been the main target for discovering trends, patterns or future expectations. However, with the recent rise in biotechnology, the powerful technology that was used for analyzing business data is now being applied to biological data. With the advanced technology at hand, the main trend in biological research is rapidly changing from structural DNA analysis to understanding cellular functions of the DNA sequences. DNA chips are now being used to perform experiments and DNA analysis processes are being used by researchers. Clustering is one of the important processes used for grouping together similar entities. There are many clustering algorithms such as hierarchical clustering, self-organizing maps, K-means clustering and so on. In this paper, we propose a clustering algorithm that imitates the ecosystem taking into account the features of biological data. We implemented the system using an Ant-Colony clustering algorithm. The system decides the number of clusters automatically. The system processes the input biological data, runs the Ant-Colony algorithm, draws the Topic Map, assigns clusters to the genes and displays the output. We tested the algorithm with a test data of 100 to1000 genes and 24 samples and show promising results for applying this algorithm to clustering DNA chip data.
Abstract: This paper presents a new fingerprint coding technique
based on contourlet transform and multistage vector quantization.
Wavelets have shown their ability in representing natural images that
contain smooth areas separated with edges. However, wavelets
cannot efficiently take advantage of the fact that the edges usually
found in fingerprints are smooth curves. This issue is addressed by
directional transforms, known as contourlets, which have the
property of preserving edges. The contourlet transform is a new
extension to the wavelet transform in two dimensions using
nonseparable and directional filter banks. The computation and
storage requirements are the major difficulty in implementing a
vector quantizer. In the full-search algorithm, the computation and
storage complexity is an exponential function of the number of bits
used in quantizing each frame of spectral information. The storage
requirement in multistage vector quantization is less when compared
to full search vector quantization. The coefficients of contourlet
transform are quantized by multistage vector quantization. The
quantized coefficients are encoded by Huffman coding. The results
obtained are tabulated and compared with the existing wavelet based
ones.
Abstract: Self-organizing map (SOM) provides both clustering and visualization capabilities in mining data. Dynamic self-organizing maps such as Growing Self-organizing Map (GSOM) has been developed to overcome the problem of fixed structure in SOM to enable better representation of the discovered patterns. However, in mining large datasets or historical data the hierarchical structure of the data is also useful to view the cluster formation at different levels of abstraction. In this paper, we present a technique to generate concept trees from the GSOM. The formation of tree from different spread factor values of GSOM is also investigated and the quality of the trees analyzed. The results show that concept trees can be generated from GSOM, thus, eliminating the need for re-clustering of the data from scratch to obtain a hierarchical view of the data under study.
Abstract: Vermicomposting is the conversion of organic waste
into bio-fertilizers through the action of earthworm. This technology
is widely used for organic solid waste management. Waste corn pulp
blended with cow dung manure was vermicomposted over 30 days
using Eisenia fetida earthworms species. pH, temperature, moisture
content, and electrical conductivity were daily monitored. The
feedstock, vermicompost and vermiwash were analyzed for nutrient
composition. The average temperature and moisture content in the
vermi-reactor was 22.5°C and 42.5% respectively. The vermicompost
and vermiwash had an almost neutral pH whilst the electrical
conductivity was 21% higher in the vermicompost. The nitrogen and
potassium content was 57% and 79.6% richer in the vermicompost
respectively compared to the vermiwash. However, the vermiwash
was 84% richer in phosphorous as compared to vermicompost.
Furthermore, the vermiwash was 89.1% and 97.6% richer in Ca and
Mg respectively and was 97.8% richer in Na salts compared to the
vermicompost. The vermiwash also indicated a significantly higher
amount of micronutrients. Both bio-fertilizers were rich in nutrients
specification for fertilizers.
Abstract: This research project is developed in order to study
managerial styles of modern Thai executives. The thorough
understanding will lead to continuous improvement and efficient
performance of Thai business organizations. Regarding managerial
skills, Thai executives focus heavily upon human skills. Also, the
negotiator roles are most emphasis in their management. In addition,
Thai executives pay most attention to the fundamental management
principles including Harmony and Unity of Direction of the
organizations. Moreover, the management techniques, consisting of
Team work and Career Planning are of their main concern. Finally,
Thai executives wish to enhance their firms- image and employees-
morale through conducting the ethical and socially responsible
activities. The major tactic deployed to stimulate employees- ethical
behaviors and mindset is Code of Ethics development.
Abstract: Information Technology (IT) projects are always
accompanied by various risks and because of high rate of failure in
such projects, managing risks in order to neutralize or at least
decrease their effects on the success of the project is strongly
essential. In this paper, fuzzy analytical hierarchy process (FAHP) is
exploited as a means of risk evaluation methodology to prioritize and
organize risk factors faced in IT projects. A real case of IT projects, a
project of design and implementation of an integrated information
system in a vehicle producing company in Iran is studied. Related
risk factors are identified and then expert qualitative judgments about
these factors are acquired. Translating these judgments to fuzzy
numbers and using them as an input to FAHP, risk factors are then
ranked and prioritized by FAHP in order to make project managers
aware of more important risks and enable them to adopt suitable
measures to deal with these highly devastative risks.
Abstract: The role of neighborhood center as semi public (the
balance space) is disappeared in bonding between private and public
in new urbanism. In this way, a hierarchical principle in the
traditional neighborhood center appears to create or develop the
conditions for residents` relationships and belonging. This paper
evaluates significant of hierarchical principles of the neighborhood
center in residents` territoriality and its factors. In this way Miandeh
neighborhood center from Boshrooyeh city was determined as a case
study area. Results indicated that a hierarchical principle is the best
instrument to improve the territoriality as the subcomponent of place
belonging in residents. The findings help the urban designer to
revitalization the neighborhoods and proceedings in organization of
physical space.
Abstract: Anaerobic treatment has many advantages over other
biological method particularly when used to treat complex
wastewater such as petroleum refinery wastewater. In this study two
Up-flow Anaerobic Sludge Blanket (UASB) reactors were operated
in parallel to treat six volumetric organic loads (0.58, 1.21, 0.89,
2.34, 1.47 and 4.14 kg COD/m3·d) to evaluate the chemical oxygen
demand (COD) removal efficiency. The reactors were continuously
adapting to the changing of operation condition with increase in the
removal efficiency or slight decrease until the last load which was
more than two times the load, at which the reactor stressed and the
removal efficiency decreased to 75% with effluent concentration of
1746 mg COD/L. Other parameters were also monitored such as pH,
alkalinity, volatile fatty acid and gas production rate. The UASB
reactor was suitable to treat petroleum refinery wastewater and the
highest COD removal rate was 83% at 1215 kg/m3·d with COD
concentration about 356 mg/L in the effluent.
Abstract: The submitted paper deals with the problems of
trapping and enriching the gases and aerosols of the substances to be
determined in the ambient atmosphere. Further, the paper is focused
on the working principle of the miniaturized portable continuous
concentrator we have designed and the possibilities of its
application in air sampling and accumulation of organic and
inorganic substances with which the air is contaminated. The stress is
laid on trapping vapours and aerosols of solid substances with the
comparatively low vapour tension such as explosive compounds.
Abstract: Dextran is a D-glucose polymer which is produced by
Leuconostoc mesenteroides grown in a sucrose-rich media. The
organism was obtained from the Persian Type Culture Collection
(PTCC) and was transferred in MRS broth medium at 30°C and pH
6.8 for 24 h. After preparation of inoculums, organisms were
inoculated into five liquid fermentation media containing either
molasses or cheese whey or different combinations of cheese whey
and molasses. After certain fermentation period, the produced
dextran was separated and dried. Dextran yield was calculated and
significant differences in different media were observed.
Furthermore, FT-IR analysis was performed and the results showed
that there were no significant differences in the produced dextran
structures.