Abstract: MiRNAs participate in gene regulation of translation.
Some studies have investigated the interactions between genes and
intragenic miRNAs. It is important to study the miRNA binding sites
of genes involved in carcinogenesis. RNAHybrid 2.1 and ERNAhybrid
programmes were used to compute the hybridization free
energy of miRNA binding sites. Of these 54 mRNAs, 22.6%, 37.7%,
and 39.7% of miRNA binding sites were present in the 5'UTRs,
CDSs, and 3'UTRs, respectively. The density of the binding sites for
miRNAs in the 5'UTR ranged from 1.6 to 43.2 times and from 1.8 to
8.0 times greater than in the CDS and 3'UTR, respectively. Three
types of miRNA interactions with mRNAs have been revealed: 5'-
dominant canonical, 3'-compensatory, and complementary binding
sites. MiRNAs regulate gene expression, and information on the
interactions between miRNAs and mRNAs could be useful in
molecular medicine. We recommend that newly described sites
undergo validation by experimental investigation.
Abstract: This paper deals with the design of a moving sliding
surface in a variable structure plant for a second order system. The
chattering phenomena is also dealt with during the switching process
for an unstable sliding surface condition. The simulation examples
considered in this paper shows the effectiveness of the sliding mode
control method used for the design of the moving sliding surfaces. A
simulink model of the continuous system was also developed in
MATLAB-SIMULINK for the design and hence demonstrated. The
phase portraits and the state plots shows the demonstration of
the powerful control technique which can be applied for second
order systems.
Abstract: In this paper, the potential use of an exponential
hidden Markov model to model a hidden pavement deterioration
process, i.e. one that is not directly measurable, is investigated. It is
assumed that the evolution of the physical condition, which is the
hidden process, and the evolution of the values of pavement distress
indicators, can be adequately described using discrete condition states
and modeled as a Markov processes. It is also assumed that condition
data can be collected by visual inspections over time and represented
continuously using an exponential distribution. The advantage of
using such a model in decision making process is illustrated through
an empirical study using real world data.
Abstract: The purpose of this research was to analyze and compare the instability of a contact surface between Copper and Nickel an alloy cathode in vacuum, the different ratio of Copper and Copper were conducted at 1%, 2% and 4% by using the cathode spot model. The transient recovery voltage is predicted. The cathode spot region is recognized as the collisionless space charge sheath connected with singly ionized collisional plasma. It was found that the transient voltage is decreased with increasing the percentage of an amount of Nickel in cathode materials.
Abstract: Active vibration control is an important problem in
structures. The objective of active vibration control is to reduce the vibrations of a system by automatic modification of the system-s
structural response. In this paper, the modeling and design of a fast
output sampling feedback controller for a smart flexible beam system embedded with shear sensors and actuators for SISO system using
Timoshenko beam theory is proposed. FEM theory, Timoshenko beam theory and the state space techniques are used to model the
aluminum cantilever beam. For the SISO case, the beam is divided into 5 finite elements and the control actuator is placed at finite
element position 1, whereas the sensor is varied from position 2 to 5, i.e., from the nearby fixed end to the free end. Controllers are
designed using FOS method and the performance of the designed FOS controller is evaluated for vibration control for 4 SISO models
of the same plant. The effect of placing the sensor at different locations on the beam is observed and the performance of the
controller is evaluated for vibration control. Some of the limitations of the Euler-Bernoulli theory such as the neglection of shear and
axial displacement are being considered here, thus giving rise to an accurate beam model. Embedded shear sensors and actuators have
been considered in this paper instead of the surface mounted sensors
and actuators for vibration suppression because of lot of advantages. In controlling the vibration modes, the first three dominant modes of
vibration of the system are considered.
Abstract: The objective this study was to characterize and
develop anthropomorphic liver phantoms in tomography hepatic
procedures for quality control and improvement professionals in
nuclear medicine. For the conformation of the anthropomorphic
phantom was used in plaster and acrylic. We constructed three
phantoms representing processes with liver cirrhosis. The phantoms
were filled with 99mTc diluted with water to obtain the scintigraphic
images. Tomography images were analyzed anterior and posterior
phantom representing a body with a greater degree cirrhotic. It was
noted that the phantoms allow the acquisition of images similar to
real liver with cirrhosis. Simulations of hemangiomas may contribute
to continued professional education of nuclear medicine, on the
question of image acquisition, allowing of the study parameters such
of the matrix, energy window and count statistics.
Abstract: Lean manufacturing is a production philosophy made
popular by Toyota Motor Corporation (TMC). It is globally known as
the Toyota Production System (TPS) and has the ultimate aim of
reducing cost by thoroughly eliminating wastes or muda. TPS
embraces the Just-in-time (JIT) manufacturing; achieving cost
reduction through lead time reduction. JIT manufacturing can be
achieved by implementing Pull system in the production.
Furthermore, TPS aims to improve productivity and creating
continuous flow in the production by arranging the machines and
processes in cellular configurations. This is called as Cellular
Manufacturing Systems (CMS). This paper studies on integrating the
CMS with the Pull system to establish a Big Island-Pull system
production for High Mix Low Volume (HMLV) products in an
automotive component industry. The paper will use the build-in JIT
system steps adapted from TMC to create the Pull system production
and also create a shojinka line which, according to takt time, has the
flexibility to adapt to demand changes simply by adding and taking
out manpower. This will lead to optimization in production.
Abstract: Masonry cavity walls are loaded by wind pressure and vertical load from upper floors. These loads results in bending moments and compression forces in the ties connecting the outer and the inner wall in a cavity wall. Large cavity walls are furthermore loaded by differential movements from the temperature gradient between the outer and the inner wall, which results in critical increase of the bending moments in the ties. Since the ties are loaded by combined compression and moment forces, the loadbearing capacity is derived from instability equilibrium equations. Most of them are iterative, since exact instability solutions are complex to derive, not to mention the extra complexity introducing dimensional instability from the temperature gradients. Using an inverse variable substitution and comparing an exact theory with an analytical instability solution a method to design tie-connectors in cavity walls was developed. The method takes into account constraint conditions limiting the free length of the wall tie, and the instability in case of pure compression which gives an optimal load bearing capacity. The model is illustrated with examples from praxis.
Abstract: The results from experimental research of deformation
by upsetting and die forging of lead specimens wit controlled impact
are presented. Laboratory setup for conducting the investigations,
which uses cold rocket engine operated with compressed air, is
described. The results show that when using controlled impact is
achieving greater plastic deformation and consumes less impact
energy than at ordinary impact deformation process.
Abstract: In this paper we have suggested a new system for egovernment.
In this method a government can design a precise and
perfect system to control people and organizations by using five
major documents. These documents contain the important
information of each member of a society and help all organizations to
do their informatics tasks through them. This information would be
available by only a national code and a secure program would
support it. The suggested system can give a good awareness to the
society and help it be managed correctly.
Abstract: Response Surface Methodology (RSM) is a powerful
and efficient mathematical approach widely applied in the
optimization of cultivation process. Cellulase enzyme production by
Trichoderma reesei RutC30 using agricultural waste rice straw and
banana fiber as carbon source were investigated. In this work,
sequential optimization strategy based statistical design was
employed to enhance the production of cellulase enzyme through
submerged cultivation. A fractional factorial design (26-2) was applied
to elucidate the process parameters that significantly affect cellulase
production. Temperature, Substrate concentration, Inducer
concentration, pH, inoculum age and agitation speed were identified
as important process parameters effecting cellulase enzyme synthesis.
The concentration of lignocelluloses and lactose (inducer) in the
cultivation medium were found to be most significant factors. The
steepest ascent method was used to locate the optimal domain and a
Central Composite Design (CCD) was used to estimate the quadratic
response surface from which the factor levels for maximum
production of cellulase were determined.
Abstract: A numerical method is proposed to calculate damping
properties for sound-proof structures involving elastic body,
viscoelastic body, and porous media. For elastic and viscoelastic body
displacement is modeled using conventional finite elements including
complex modulus of elasticity. Both effective density and bulk
modulus have complex quantities to represent damped sound fields in
the porous media. Particle displacement in the porous media is
discretised using finite element method. Displacement vectors as
common unknown variables are solved under coupled condition
between elastic body, viscoelastic body and porous media. Further,
explicit expressions of modal loss factor for the mixed structures are
derived using asymptotic method. Eigenvalue analysis and frequency
responded were calculated for automotive test panel laminated
viscoelastic and porous structures using this technique, the results
almost agreed with the experimental results.
Abstract: With the prevalence of computer and development of information technology, Geographic Information Systems (GIS) have long used for a variety of applications in electrical engineering. GIS are designed to support the analysis, management, manipulation and mapping of spatial data. This paper presents several usages of GIS in power utilities such as automated route selection for the construction of new power lines which uses a dynamic programming model for route optimization, load forecasting and optimizing planning of substation-s location and capacity with comprehensive algorithm which involves an accurate small-area electric load forecasting procedure and simulates the different cost functions of substations.
Abstract: The previous researches focused on the influence of
anthropogenic greenhouse gases exerting global warming, but not
consider whether desert sand may warm the planet, this could be
improved by accounting for sand's physical and geometric properties.
Here we show, sand particles (because of their geometry) at the desert
surface form an extended surface of up to 1 + π/4 times the planar area
of the desert that can contact sunlight, and at shallow depths of the
desert form another extended surface of at least 1 + π times the planar
area that can contact air. Based on this feature, an enhanced heat
exchange system between sunlight, desert sand, and air in the spaces
between sand particles could be built up automatically, which can
increase capture of solar energy, leading to rapid heating of the sand
particles, and then the heating of sand particles will dramatically heat
the air between sand particles. The thermodynamics of deserts may
thus have contributed to global warming, especially significant to
future global warming if the current desertification continues to
expand.
Abstract: This article proposes a current-mode square-rooting
circuit using current follower transconductance amplifier (CTFA).
The amplitude of the output current can be electronically controlled
via input bias current with wide input dynamic range. The proposed
circuit consists of only single CFTA. Without any matching
conditions and external passive elements, the circuit is then
appropriate for an IC architecture. The magnitude of the output signal
is temperature-insensitive. The PSpice simulation results are
depicted, and the given results agree well with the theoretical
anticipation. The power consumption is approximately 1.96mW at
±1.5V supply voltages.
Abstract: The amount and heterogeneity of data in biomedical research, notably in interdisciplinary research, requires new methods for the collection, presentation and analysis of information. Important data from laboratory experiments as well as patient trials are available but come out of distributed resources. The Charite Medical School in Berlin has established together with the German Research Foundation (DFG) a new information service center for kidney diseases and transplantation (Open European Nephrology Science Centre - OpEN.SC). The system is based on a service-oriented architecture (SOA) with main and auxiliary modules arranged in four layers. To improve the reuse and efficient arrangement of the services the functionalities are described as business processes using the standardised Business Process Execution Language (BPEL).
Abstract: The pigments covered by film-forming polymers have
opened a prospect to improve the quality of water-based printing
inks. In this study such pigments were prepared by the initiated
polymerization of styrene and methacrylate derivative monomers in
the aqueous pigment dispersions. The formation of polymer films
covering pigment cores depends on the polymerization time and the
ratio of pigment to monomers. At the time of 4 hours and the ratio of
1/10 almost pigment particles are coated by the polymer. The formed
polymer covers of pigments have the average thickness of 5.95 nm.
The size increasing percentage of the coated particles after a week is
4.5 %, about fourteen-fold lower than of the original ones. The
obtained results indicate that the coated pigments are improved
dispersion stability in water medium along with a guarantee for the
optical colour.
Abstract: Laminar natural-convective heat transfer from a
horizontal cylinder is studied by solving the Navier-Stokes and
energy equations using higher order compact scheme in cylindrical
polar coordinates. Results are obtained for Rayleigh numbers of 1,
10, 100 and 1000 for a Prandtl number of 0.7. The local Nusselt
number and mean Nusselt number are calculated and compared with
available experimental and theoretical results. Streamlines, vorticity -
lines and isotherms are plotted.
Abstract: People have always needed to believe in some
supernatural power, which could explain nature phenomena.
Different kinds of religions like Christianity, Hinduism, Islam,
Buddhism have thought believers in all world, how to behave
themselves. We think the most important role of religion in modern
society most important role of religion in modern society is safety of
the People. World and traditional religion played a prominent role in
the socio-cultural progress, and in the development of man as a
spiritual being. At the heart of religious morals the belief in god and
responsibility before it lies and specifies religious and ethical values
and categories . The religion is based on ethical standards historically
developed by society, requirements and concepts, but it puts all
social and moral relations of the person in dependence on religious
values. For everything that the believer makes on a debt or a duty, he
bears moral responsibility before conscience, people and god. The
concept of value of religious morals takes the central place because
the religion from all forms of public consciousness most values is
painted as it is urged to answer vital questions. Any religion not only
considers questions of creation of the world, sense of human
existence, relationship of god and the person, but also offers the
ethical concept, develops rules of behavior of people. The religion a
long time dominated in the history of culture, and during this time
created a set of cultural and material values. The identity of Kazakh
culture can be defined as a Cultural identity traditional ,national
identity and the identity values developed by Kazakh people in
process of cultural-historical development, promoting formation of
Kazakh culture identity on public consciousness. Identity is the
historical process but always the tradition exists in it as a component
of stability, as a component of self that what this identity formed .
Abstract: Designing and implementing intelligent systems has become a crucial factor for the innovation and development of better products of space technologies. A neural network is a parallel system, capable of resolving paradigms that linear computing cannot. Field programmable gate array (FPGA) is a digital device that owns reprogrammable properties and robust flexibility. For the neural network based instrument prototype in real time application, conventional specific VLSI neural chip design suffers the limitation in time and cost. With low precision artificial neural network design, FPGAs have higher speed and smaller size for real time application than the VLSI and DSP chips. So, many researchers have made great efforts on the realization of neural network (NN) using FPGA technique. In this paper, an introduction of ANN and FPGA technique are briefly shown. Also, Hardware Description Language (VHDL) code has been proposed to implement ANNs as well as to present simulation results with floating point arithmetic. Synthesis results for ANN controller are developed using Precision RTL. Proposed VHDL implementation creates a flexible, fast method and high degree of parallelism for implementing ANN. The implementation of multi-layer NN using lookup table LUT reduces the resource utilization for implementation and time for execution.