Abstract: In recent years a new method of combination
treatment for cancer has been developed and studied that has led to
significant advancements in the field of cancer therapy. Hyperthermia
is a traditional therapy that, along with a creation of a medically
approved level of heat with the help of an alternating magnetic AC
current, results in the destruction of cancer cells by heat. This paper
gives details regarding the production of the spherical nanocomposite
PVA/γ-Fe2O3 in order to be used for medical purposes such as tumor
treatment by hyperthermia. To reach a suitable and evenly distributed
temperature, the nanocomposite with core-shell morphology and
spherical form within a 100 to 200 nanometer size was created using
phase separation emulsion, in which the magnetic nano-particles γ-
Fe2O3 with an average particle size of 20 nano-meters and with
different percentages of 0.2, 0.4, 0.5 and 0.6 were covered by
polyvinyl alcohol. The main concern in hyperthermia and heat
treatment is achieving desirable specific absorption rate (SAR) and
one of the most critical factors in SAR is particle size. In this project
all attempts has been done to reach minimal size and consequently
maximum SAR. The morphological analysis of the spherical
structure of the nanocomposite PVA/γ-Fe2O3 was achieved by SEM
analyses and the study of the chemical bonds created was made
possible by FTIR analysis. To investigate the manner of magnetic
nanocomposite particle size distribution a DLS experiment was
conducted. Moreover, to determine the magnetic behavior of the γ-
Fe2O3 particle and the nanocomposite PVA/γ-Fe2O3 in different
concentrations a VSM test was conducted. To sum up, creating
magnetic nanocomposites with a spherical morphology that would be
employed for drug loading opens doors to new approaches in
developing nanocomposites that provide efficient heat and a
controlled release of drug simultaneously inside the magnetic field,
which are among their positive characteristics that could significantly
improve the recovery process in patients.
Abstract: The degradation of concrete due to various hygrochemo-
mechanical actions is inevitable for the structures particularly
built to store water. Therefore, it is essential to determine the material
properties of dam-like structures due to ageing to predict the behavior
of such structures after a certain age. The degraded material
properties are calculated by introducing isotropic degradation index.
The predicted material properties are used to study the behavior of
aged dam at different ages. The dam is modeled by finite elements
and displacement and is considered as an unknown variable. The
parametric study reveals that the displacement is quite larger for
comparatively lower design life of the structure because the
degradation of elastic properties depends on the design life of the
dam. The stresses in dam cam be unexpectedly large at any age with
in the design life. The outcomes of the present study indicate the
importance of the consideration ageing effect of concrete exposed to
water for the safe design of dam throughout its life time.
Abstract: This paper presents an experimental study on
structural performance of an innovative noise barrier consisting of
poly-block, light polyurethane foam (LPF) and polyurea. This wall
system (flexi-wall) is intended to be employed as a vertical extension
to existing sound barriers in an accelerated construction method. To
aid in the wall design, several mechanical tests were conducted on
LPF specimens and two full-scale walls were then fabricated
employing the same LPF material. The full-scale walls were
subjected to lateral loading in order to establish their lateral
resistance. A cyclic fatigue test was also performed on a full-scale
flexi-wall in order to evaluate the performance of the wall under a
repetitive loading condition. The result of the experiments indicated
the suitability of flexi-wall in accelerated construction and confirmed
that the structural performance of the wall system under lateral
loading is satisfactory for the sound barrier application. The
experimental results were discussed and a preliminary design
procedure for application of flexi-wall in sound barrier applications
was also developed.
Abstract: Biodiesel, as an alternative renewable fuel, has been
receiving increasing attention due to the limited supply of fossil fuels
and the increasing need for energy. Microalgae are promising source
for lipids, which can be converted to biodiesel. The biodiesel
production from microalgae lipids using lipase catalyzed reaction in
supercritical CO2 medium has several advantages over conventional
production processes. However, identifying the optimum microalgae
lipid extraction and transesterification conditions is still a challenge.
In this study, the quality of biodiesel produced from lipids extracted
from Scenedesmus sp. and their enzymatic transesterification using
supercritical carbon dioxide have been investigated. At the optimum
conditions, the highest biodiesel production yield was found to be
82%. The fuel properties of the produced biodiesel, without any
separation step, at optimum reaction condition, were determined and
compared to ASTM standards. The properties were found to comply
with the limits, and showed a low glycerol content, without any
separation step.
Abstract: The legality of some countries or agencies’ acts to spy
on personal phone calls of the public became a hot topic to many
social groups’ talks. It is believed that this act is considered an
invasion to someone’s privacy. Such act may be justified if it is
singling out specific cases but to spy without limits is very
unacceptable. This paper discusses the needs for not only a simple
and light weight technique to secure mobile voice calls but also a
technique that is independent from any encryption standard or library.
It then presents and tests one encrypting algorithm that is based of
Frequency scrambling technique to show fair and delay-free process
that can be used to protect phone calls from such spying acts.
Abstract: The notion of power and gender domination is one of
the inseparable aspects of themes in postmodern literature. The
reason of its importance has been discussed frequently since the rise
of Michel Foucault and his insight into the circulation of power and
the transgression of forces. Language and society operate as the basic
grounds for the study, as all human beings are bound to the set of
rules and norms which shape them in the acceptable way in the
macrocosm. How different genders in different positions behave and
show reactions to the provocation of social forces and superiority of
one another is of great interest to writers and literary critics. Mamet’s
works are noticeable for their controversial but timely themes which
illustrate human conflicts with the society and greed for power. Many
critics like Christopher Bigsby and Harold Bloom have discussed
Mamet and his ideas in recent years. This paper is the study of
Oleanna, Mamet’s masterpiece about the teacher-student relationship
and the circulation of power between a man and woman. He shows
the very breakable boundaries in the domination of a gender and the
downfall of speech as the consequence of transgression and freedom.
The failure of the language the teacher uses and the abuse of his own
words by a student who seeks superiority and knowledge are the
main subjects of the discussion. Supported by the ideas of Foucault,
the language Mamet uses to present his characters becomes the
fundamental premise in this study. As a result, language becomes
both the means of achievement and downfall.
Abstract: The article represents the results of isolation and
component chromatographic analysis of essential oils of Polygonum
L. plants growing in Kazakhstan in commercial reserves at the
territory of Kazakhstan. The results of research of antibacterial and
antifungal activity of isolated compounds have been represented.
Abstract: Floorplanning plays a vital role in the physical design
process of Very Large Scale Integrated (VLSI) chips. It is an
essential design step to estimate the chip area prior to the optimized
placement of digital blocks and their interconnections. Since VLSI
floorplanning is an NP-hard problem, many optimization techniques
were adopted in the literature. In this work, a music-inspired
Harmony Search (HS) algorithm is used for the fixed die outline
constrained floorplanning, with the aim of reducing the total chip
area. HS draws inspiration from the musical improvisation process of
searching for a perfect state of harmony. Initially, B*-tree is used to
generate the primary floorplan for the given rectangular hard
modules and then HS algorithm is applied to obtain an optimal
solution for the efficient floorplan. The experimental results of the
HS algorithm are obtained for the MCNC benchmark circuits.
Abstract: In this study free vibration analysis of aluminum
honeycomb sandwich structures were carried out experimentally and
numerically. The natural frequencies and mode shapes of sandwich
structures fabricated with different configurations for clamped-free
boundary condition were determined. The effects of lower and upper
face sheet thickness, the core material thickness, cell diameter, cell
angle and foil thickness on the vibration characteristics were
examined. The numerical studies were performed with ANSYS
package. While the sandwich structures were modeled in ANSYS the
continuum model was used. Later, the numerical results were
compared with the experimental findings.
Abstract: The future and the development of science is therefore
seen in interdisciplinary areas such as biomedical engineering. Selfassembled
structures, similar to stem cell niches would inhibit fast
division process and subsequently capture the stem cells from the
blood flow. By means of surface topography and the stiffness as well
as microstructure progenitor cells should be differentiated towards
the formation of endothelial cells monolayer which effectively will
inhibit activation of the coagulation cascade. The idea of the material
surface development met the interest of the clinical institutions,
which support the development of science in this area and are waiting
for scientific solutions that could contribute to the development of
heart assist systems. This would improve the efficiency of the
treatment of patients with myocardial failure, supported with artificial
heart assist systems. Innovative materials would enable the redesign,
in the post project activity, construction of ventricular heart assist.
Abstract: Tuberculosis (TB) remains a leading cause of
infectious mortality. It is primarily transmitted by the respiratory
route, individuals with active disease may infect others through
airborne particles which releases when they cough, talk, or sing and
subsequently inhale by others. In order to study the effect of the
Bacilli Calmette-Guerin (BCG) vaccine after vaccination of TB
patient, a Vaccinated Susceptible Infected and Recovered (VSIR)
mathematical model is being developed to achieve the desired
objectives. The mathematical model, so developed, shall be used to
quantify the effect of BCG Vaccine to protect the immigrant young
adult person. Moreover, equations are to be established for the
disease endemic and free equilibrium states and subsequently utilized
in disease stability analysis. The stability analysis will give a
complete picture of disease annihilation from the total population if
the total removal rate from the infectious group should be greater
than total number of dormant infections produced throughout
infectious period.
Abstract: In this paper, we propose a new method for threedimensional
object indexing based on D.A.M.C-S.H.C descriptor
(Direct and Analytical Method for Calculating the Spherical
Harmonics Coefficients). For this end, we propose a direct
calculation of the coefficients of spherical harmonics with perfect
precision. The aims of the method are to minimize, the processing
time on the 3D objects database and the searching time of similar
objects to a request object.
Firstly we start by defining the new descriptor using a new
division of 3-D object in a sphere. Then we define a new distance
which will be tested and prove his efficiency in the search for similar
objects in the database in which we have objects with very various
and important size.
Abstract: This paper proposed the comparison made between
Multi-Carrier Pulse Width Modulation, Sinusoidal Pulse Width
Modulation and Selective Harmonic Elimination Pulse Width
Modulation technique for minimization of Total Harmonic Distortion
in Cascaded H-Bridge Multi-Level Inverter. In Multicarrier Pulse
Width Modulation method by using Alternate Position of Disposition
scheme for switching pulse generation to Multi-Level Inverter.
Another carrier based approach; Sinusoidal Pulse Width Modulation
method is also implemented to define the switching pulse generation
system in the multi-level inverter. In Selective Harmonic Elimination
method using Genetic Algorithm and Particle Swarm Optimization
algorithm for define the required switching angles to eliminate low
order harmonics from the inverter output voltage waveform and
reduce the total harmonic distortion value. So, the results validate that
the Selective Harmonic Elimination Pulse Width Modulation method
does capably eliminate a great number of precise harmonics and
minimize the Total Harmonic Distortion value in output voltage
waveform in compared with Multi-Carrier Pulse Width Modulation
method, Sinusoidal Pulse Width Modulation method. In this paper,
comparison of simulation results shows that the Selective Harmonic
Elimination method can attain optimal harmonic minimization
solution better than Multi-Carrier Pulse Width Modulation method,
Sinusoidal Pulse Width Modulation method.
Abstract: This study aimed to determine the possible protective effects of L‐carnitine against gentamicin‐induced nephrotoxicity. Forty male albino rats were divided into 4 groups (10 rats each); Group 1: normal control, group 2: induced nephrotoxicity (gentamicin 50 mg/kg/day S.C; 8 days), group 3: treated with L‐ carnitine (40 mg/kg/d SC for 12 days) and group 4: treated with L‐ carnitine 4 days before and for 8 days in concomitant with gentamicin. Gentamicin‐induced nephrotoxicity (group 2): caused significant increase in serum urea, creatinine, urinary N‐acetyl‐B‐D‐ glucosaminidase (NAG), gamma glutamyl transpeptidase (GGT), urinary total protein and kidney tissue malondialdehyde (MDA) with significant decrease in serum superoxide dismutase (SOD), serum catalase and creatinine clearance and marked tubular necrosis in the proximal convoluted tubules with interruption in the basement membrane around the necrotic tubule compared to the normal control group. L‐carnitine 4 days before and for 8 days in concomitant with gentamicin (group 4) offered marked decrease in serum urea, serum creatinine, urinary NAG, urinary GGT, urinary proteins and kidney tissue MDA, with marked increase in serum SOD, serum catalase and creatinine clearance with marked improvement in the tubular damage compared to gentamicin‐induced nephrotoxicity group. L‐carnitine administered for 12 days produced no change in the parameters mentioned above as compared to the normal control group. In conclusion: L‐carnitine could reduce most of the biochemical parameters and also improve the histopathological features of kidney asscociated with gentamicin induced‐nephrotoxicity.
Abstract: Hemoglobin (HB) indicates anemia level and by
extension may reflect the nutritional level and perhaps the immunity
of an individual. Some antiretroviral drugs like Zidovudine are
known to cause anemia in people living with HIV/AIDS (PLWHA).
A cross sectional study using demographic data and blood specimen
from 218 female commercial sex workers attending antiretroviral
therapy (ART) clinics was conducted between December, 2009 and
July, 2011 to assess the effect of zidovudine on hematologic, and
RNA viral load of female sex workers receiving antiretroviral
treatment in north western Nigeria. Anemia is a common and serious
complication of both HIV infection and its treatment. In the setting of
HIV infection, anemia has been associated with decreased quality of
life, functional status, and survival. Antiretroviral therapy,
particularly the highly active antiretroviral therapy (HAART), has
been associated with a decrease in the incidence and severity of
anemia in HIV-infected patients who have received a HAART
regimen for at least 1 year. In this study, result has shown that of the
218 patients, 26 with hemoglobin count between 5.1 – 10g/dl were
observed to have the highest viral load count of 300,000 –
350,000copies/ml. It was also observed that most patients (190) with
HB of 10.1 – 15.0g/dl had viral load count of 200,000 – 250,000
copies /ml. An inverse relationship therefore exists i.e. the lower the
hemoglobin level, the higher the viral load count even though the test
statistics did not show any significance between the two (P = 0.206).
This shows that multivariate logistic regression analysis
demonstrated that anemia was associated with a CD4 + cell count
below 50/μL, female sex workers with a viral load above 100,000
copies/mL, who use zidovudine.
Severe anemia was less prevalent in this study population than in
historical comparators; however, mild to moderate anemia rates
remain high. The study therefore recommends that hematological and
virologic parameters be monitored closely in patients receiving first
line ART regimen.
Abstract: Riveting process is one of the important ways to keep
fastening the lap joints in aircraft structures. Failure of aircraft lap
joints directly depends on the stress field in the joint. An important
application of riveting process is in the construction of aircraft
fuselage structures. In this paper, a 3D finite element method is
carried out in order to optimize residual stress field in a riveted lap
joint and also to estimate its fatigue life. In continue, a number of
experiments are designed and analyzed using design of experiments
(DOE). Then, Taguchi method is used to select an optimized case
between different levels of each factor. Besides that, the factor which
affects the most on residual stress field is investigated. Such
optimized case provides the maximum residual stress field. Fatigue
life of the optimized joint is estimated by Paris-Erdogan law. Stress
intensity factors (SIFs) are calculated using both finite element
analysis and experimental formula. In addition, the effect of residual
stress field, geometry and secondary bending are considered in SIF
calculation. A good agreement is found between results of such
methods. Comparison between optimized fatigue life and fatigue life
of other joints has shown an improvement in the joint’s life.
Abstract: Out-migration is an important issue for Georgia as
well as since independence has loosed due to emigration one fifth of
its population. During Soviet time out-migration from USSR was
almost impossible and one of the most important instruments in
regulating population movement within the Soviet Union was the
system of compulsory residential registrations, so-called “propiska”.
Since independent here was not any regulation for migration from
Georgia. The majorities of Georgian migrants go abroad by tourist
visa and then overstay, becoming the irregular labor migrants. The
official statistics on migration published for this period was based on
the administrative system of population registration, were
insignificant in terms of numbers and did not represent the real scope
of these migration movements. This paper discusses the data quality
and methodology of migration statistics in Georgia and we are going
to answer the questions: what is the real reason of increasing
immigration flows according to the official numbers since 2000s?
Abstract: The numerical simulation has made tremendous
advances in investigating the blood flow phenomenon through elastic
arteries. Such study can be useful in demonstrating the disease
progression and hemodynamics of cardiovascular diseases such as
atherosclerosis. In the present study, patient specific case diagnosed
with partially stenosed complete right ICA and normal left carotid
bifurcation without any atherosclerotic plaque formation is
considered. 3D patient specific carotid bifurcation model is generated
based on CT scan data using MIMICS-4.0 and numerical analysis is
performed using FSI solver in ANSYS-14.5. The blood flow is
assumed to be incompressible, homogenous and Newtonian, while
the artery wall is assumed to be linearly elastic. The two-way
sequentially coupled transient FSI analysis is performed using FSI
solver for three pulse cycles. The hemodynamic parameters such as
flow pattern, Wall Shear Stress, pressure contours and arterial wall
deformation are studied at the bifurcation and critical zones such as
stenosis. The variation in flow behavior is studied throughout the
pulse cycle. Also, the simulation results reveal that there is a
considerable increase in the flow behavior in stenosed carotid in
contrast to the normal carotid bifurcation system. The investigation
also demonstrates the disturbed flow pattern especially at the
bifurcation and stenosed zone elevating the hemodynamics,
particularly during peak systole and later part of the pulse cycle. The
results obtained agree well with the clinical observation and
demonstrates the potential of patient specific numerical studies in
prognosis of disease progression and plaque rupture.
Abstract: This paper represents the results of experimental work to investigate the suitability of a waste material (WM) for soft soil stabilisation. In addition, the effect of particle size distribution (PSD) of the waste material on its performance as a soil stabiliser was investigated. The WM used in this study is produced from the incineration processes in domestic energy power plant and it is available in two different grades of fineness (coarse waste material (CWM) and fine waste material (FWM)). An intermediate plasticity silty clayey soil with medium organic matter content has been used in this study. The suitability of the CWM and FWM to improve the physical and engineering properties of the selected soil was evaluated dependant on the results obtained from the consistency limits, compaction characteristics (optimum moisture content (OMC) and maximum dry density (MDD)); along with the unconfined compressive strength test (UCS). Different percentages of CWM were added to the soft soil (3, 6, 9, 12 and 15%) to produce various admixtures. Then the UCS test was carried out on specimens under different curing periods (zero, 7, 14, and 28 days) to find the optimum percentage of CWM. The optimum and other two percentages (either side of the optimum content) were used for FWM to evaluate the effect of the fineness of the WM on UCS of the stabilised soil. Results indicated that both types of the WM used in this study improved the physical properties of the soft soil where the index of plasticity (IP) was decreased significantly. IP was decreased from 21 to 13.64 and 13.10 with 12% of CWM and 15% of FWM respectively. The results of the unconfined compressive strength test indicated that 12% of CWM was the optimum and this percentage developed the UCS value from 202kPa to 500kPa for 28 days cured samples, which is equal, approximately 2.5 times the UCS value for untreated soil. Moreover, this percentage provided 1.4 times the value of UCS for stabilized soil-CWA by using FWM which recorded just under 700kPa after 28 days curing.
Abstract: We report herein the development and preliminary mechanical characterization of fully-dense multi-wall carbon nanotube (MWCNT)-reinforced ceramics and glasses based on a completely new methodology termed High Shear Compaction (HSC). The tubes are introduced and bound to the matrix grains by aid of polymeric binders to form flexible green bodies which are sintered and densified by spark plasma sintering to unprecedentedly high densities of 100% of the pure-matrix value. The strategy was validated across a PyrexTM glass / MWCNT composite while no identifiable factors limit application to other types of matrices. Nondestructive evaluation, based on ultrasonics, of the dynamic mechanical properties of the materials including elastic, shear and bulk modulus as well as Poisson’s ratio showed optimum property improvement at 0.5 %wt tube loading while evidence of nanoscalespecific energy dissipative characteristics acting complementary to nanotube bridging and pull-out indicate a high potential in a wide range of reinforcing and multifunctional applications.