Abstract: A spectrophotometric method was developed for simultaneous quantification of pseudoephedrine hydrochloride (PSE) triprolidine hydrochloride (TRI) using second derivative method (zero-crossing technique). The second derivative amplitudes of PSE and TRI were measured at 271 and 321 nm, respectively. The calibration curves were linear in the range of 200 to 1,000 g/ml for PSE and 10 to 50 g/ml for TRI. The method was validated for specificity, accuracy, precision, limit of detection and limit of quantitation. The proposed method was applied to the assaying and dissolution of PSE and TRI in commercial tablets without any chemical separation. The results were compared with those obtained by the official USP31 method and statistical tests showed that there is no significant between the methods at 95% confidence level. The proposed method is simple, rapid and suitable for the routine quality control application. KeywordsTriprolidine, Pseudoephedrine, Derivative spectrophotometry, Dissolution testing.
Abstract: Rule Discovery is an important technique for mining knowledge from large databases. Use of objective measures for discovering interesting rules lead to another data mining problem, although of reduced complexity. Data mining researchers have studied subjective measures of interestingness to reduce the volume of discovered rules to ultimately improve the overall efficiency of KDD process. In this paper we study novelty of the discovered rules as a subjective measure of interestingness. We propose a hybrid approach that uses objective and subjective measures to quantify novelty of the discovered rules in terms of their deviations from the known rules. We analyze the types of deviation that can arise between two rules and categorize the discovered rules according to the user specified threshold. We implement the proposed framework and experiment with some public datasets. The experimental results are quite promising.
Abstract: This paper presents a model for the evaluation of
energy performance and aerodynamic forces acting on a three-bladed
small vertical axis Darrieus wind turbine depending on blade chord
curvature with respect to rotor axis.
The adopted survey methodology is based on an analytical code
coupled to a solid modeling software, capable of generating the
desired blade geometry depending on the blade design geometric
parameters, which is linked to a finite volume CFD code for the
calculation of rotor performance.
After describing and validating the model with experimental data,
the results of numerical simulations are proposed on the bases of two
different blade profile architectures, which are respectively
characterized by a straight chord and by a curved one, having a chord
radius equal to rotor external circumference. A CFD campaign of
analysis is completed for three blade-candidate airfoil sections, that is
the recently-developed DU 06-W-200 cambered blade profile, a
classical symmetrical NACA 0021 and its derived cambered airfoil,
characterized by a curved chord, having a chord radius equal to rotor
external circumference.
The effects of blade chord curvature on angle of attack, blade
tangential and normal forces are first investigated and then the
overall rotor torque and power are analyzed as a function of blade
azimuthal position, achieving a numerical quantification of the
influence of blade camber on overall rotor performance.
Abstract: We consider linear regression models where both input data (the values of independent variables) and output data (the observations of the dependent variable) are interval-censored. We introduce a possibilistic generalization of the least squares estimator, so called OLS-set for the interval model. This set captures the impact of the loss of information on the OLS estimator caused by interval censoring and provides a tool for quantification of this effect. We study complexity-theoretic properties of the OLS-set. We also deal with restricted versions of the general interval linear regression model, in particular the crisp input – interval output model. We give an argument that natural descriptions of the OLS-set in the crisp input – interval output cannot be computed in polynomial time. Then we derive easily computable approximations for the OLS-set which can be used instead of the exact description. We illustrate the approach by an example.
Abstract: Most often the contaminants are not taken seriously into consideration, and this behavior comes out directly from the lack of monitoring and professional reporting about pollution in the printing facilities in Serbia. The goal of planned and systematic ozone measurements in ambient air of the screen printing facilities in Novi Sad is to examine of its impact on the employees health, and to track trends in concentration. In this study, ozone concentrations were determined by using discontinuous and continuous method during the automatic and manual screen printing process. Obtained results indicates that the average concentrations of ozone measured during the automatic process were almost 3 to 28 times higher for discontinuous and 10 times higher for continuous method (1.028 ppm) compared to the values prescribed by OSHA. In the manual process, average concentrations of ozone were within prescribed values for discontinuous and almost 3 times higher for continuous method (0.299 ppm).
Abstract: Software reliability, defined as the probability of a
software system or application functioning without failure or errors
over a defined period of time, has been an important area of research
for over three decades. Several research efforts aimed at developing
models to improve reliability are currently underway. One of the
most popular approaches to software reliability adopted by some of
these research efforts involves the use of operational profiles to
predict how software applications will be used. Operational profiles
are a quantification of usage patterns for a software application. The
research presented in this paper investigates an innovative multiagent
framework for automatic creation and management of
operational profiles for generic distributed systems after their release
into the market. The architecture of the proposed Operational Profile
MAS (Multi-Agent System) is presented along with detailed
descriptions of the various models arrived at following the analysis
and design phases of the proposed system. The operational profile in
this paper is extended to comprise seven different profiles. Further,
the criticality of operations is defined using a new composed metrics
in order to organize the testing process as well as to decrease the time
and cost involved in this process. A prototype implementation of the
proposed MAS is included as proof-of-concept and the framework is
considered as a step towards making distributed systems intelligent
and self-managing.
Abstract: This paper presents a model for the evaluation of
energy performance and aerodynamic forces acting on a small
straight-bladed Darrieus-type vertical axis wind turbine depending on
blade geometrical section. It consists of an analytical code coupled to
a solid modeling software, capable of generating the desired blade
geometry based on the desired blade design geometric parameters.
Such module is then linked to a finite volume commercial CFD code
for the calculation of rotor performance by integration of the
aerodynamic forces along the perimeter of each blade for a full period
of revolution.After describing and validating the computational
model with experimental data, the results of numerical simulations
are proposed on the bases of two candidate airfoil sections, that is a
classical symmetrical NACA 0021 blade profile and the recently
developed DU 06-W-200 non-symmetric and laminar blade
profile.Through a full CFD campaign of analysis, the effects of blade
geometrical section on angle of attack are first investigated and then
the overall rotor torque and power are analyzed as a function of blade
azimuthal position, achieving a numerical quantification of the
influence of airfoil geometry on overall rotor performance.
Abstract: This study aims to demonstrate the quantification of
peptides based on isotope dilution surface enhanced Raman
scattering (IDSERS). SERS spectra of phenylalanine (Phe), leucine
(Leu) and two peptide sequences TGQIFK (T13) and
YSFLQNPQTSLCFSESIPTPSNR (T6) as part of the 22-kDa
human growth hormone (hGH) were obtained on Ag-nanoparticle
covered substrates. On the basis of the dominant Phe and Leu
vibrational modes, precise partial least squares (PLS) prediction
models were built enabling the determination of unknown T13 and
T6 concentrations. Detection of hGH in its physiological
concentration in order to investigate the possibility of protein
quantification has been achieved.
Abstract: Introducing survivability into embedded real-time system (ERTS) can improve the survivability power of the system. This paper mainly discusses about the survivability of ERTS. The first is the survivability origin of ERTS. The second is survivability analysis. According to the definition of survivability based on survivability specification and division of the entire survivability analysis process for ERTS, a survivability analysis profile is presented. The quantitative analysis model of this profile is emphasized and illuminated in detail, the quantifying analysis of system was showed helpful to evaluate system survivability more accurate. The third is platform design of survivability analysis. In terms of the profile, the analysis process is encapsulated and assembled into one platform, on which quantification, standardization and simplification of survivability analysis are all achieved. The fourth is survivability design. According to character of ERTS, strengthened design method is selected to realize system survivability design. Through the analysis of embedded mobile video-on-demand system, intrusion tolerant technology is introduced in whole survivability design.
Abstract: Using a texture database, a statistical estimation of
spring-back was conducted in this study on the basis of statistical
analysis. Both spring-back in bending deformation and experimental
data related to the crystal orientation show significant dispersion.
Therefore, a probabilistic statistical approach was established for the
proper quantification of these values. Correlation was examined
among the parameters F(x) of spring-back, F(x) of the buildup fraction
to three orientations after 92° bending, and F(x) at an as-received part
on the basis of the three-parameter Weibull distribution. Consequent
spring-back estimation using a texture database yielded excellent
estimates compared with experimental values.
Abstract: It is sometimes difficult to differentiate between
innocent murmurs and pathological murmurs during auscultation. In
these difficult cases, an intelligent stethoscope with decision support
abilities would be of great value. In this study, using a dog model,
phonocardiographic recordings were obtained from 27 boxer dogs
with various degrees of aortic stenosis (AS) severity. As a reference
for severity assessment, continuous wave Doppler was used. The data
were analyzed with recurrence quantification analysis (RQA) with
the aim to find features able to distinguish innocent murmurs from
murmurs caused by AS. Four out of eight investigated RQA features
showed significant differences between innocent murmurs and
pathological murmurs. Using a plain linear discriminant analysis
classifier, the best pair of features (recurrence rate and entropy)
resulted in a sensitivity of 90% and a specificity of 88%. In
conclusion, RQA provide valid features which can be used for
differentiation between innocent murmurs and murmurs caused by
AS.
Abstract: Construction of tunnels is connected with high
uncertainty in the field of costs, construction period, safety and
impact on surroundings. Risk management became therefore a
common part of tunnel projects, especially after a set of fatal
collapses occurred in 1990's. Such collapses are caused usually by
combination of factors that can be divided into three main groups, i.e.
unfavourable geological conditions, failures in the design and
planning or failures in the execution.
This paper suggests a procedure enabling quantification of the
excavation risk related to extraordinary accidents using FTA and
ETA tools. It will elaborate on a common process of risk analysis and
enable the transfer of information and experience between particular
tunnel construction projects. Further, it gives a guide for designers,
management and other participants, how to deal with risk of such
accidents and how to make qualified decisions based on a
probabilistic approach.
Abstract: The main objective of this paper is to analyse the influence of preparation and control of orders on performance. The focused activities explored in this research are: procurement, production and distribution. These changes in performance were obtained through improvement of the supply chain. It is proved using all the company activities that it is possible to increase de efficiency and do services in an adequate way, placing the products in the market efficiently. For that, it was explored the importance of the supply chain, with privilege to the practical environment and the quantification of the obtained results.
Abstract: The culture of riding heavy motorcycles originates
from advanced countries and mainly comes from Europe, North
America, and Japan. Heavy duty motorcycle riders are different from
people who view motorcycles as a convenient mean of transportation.
They regard riding them as a kind of enjoyment and high-level taste.
The activities of riding heavy duty motorcycles have formes a
distinctive landscape in domestic land in Taiwan. Previous studies
which explored motorcycle culture in Taiwan still focused on the
objects of motorcycle engine displacement under 50 cc.. The study
aims to study the heavy duty motorcycles of engine displacement over
550 cc. and explores where their attractiveness is. For finding the
attractiveness of heavy duty motorcycle, the study chooses Miryoku
Engineering (Preference-Based Design) approach. Two steps are
adopted to proceed the research. First, through arranging the letters
obtained from interviewing experts, EGM (The Evaluation Grid
Method) was applied to find out the structure of attractiveness. The
attractive styles are eye-dazzling, leisure, classic, and racing
competitive styles. Secondarily, Quantification Theory Type I analysis
was adopted as a tool for analyzing the importance of attractiveness.
The relationship between style and attractive parts was also discussed.
The results could contribute to the design and research development of
heavy duty motorcycle industry in Taiwan.
Abstract: Segmentation and quantification of stenosis is an
important task in assessing coronary artery disease. One of the main
challenges is measuring the real diameter of curved vessels.
Moreover, uncertainty in segmentation of different tissues in the
narrow vessel is an important issue that affects accuracy. This paper
proposes an algorithm to extract coronary arteries and measure the
degree of stenosis. Markovian fuzzy clustering method is applied to
model uncertainty arises from partial volume effect problem. The
algorithm employs: segmentation, centreline extraction, estimation of
orthogonal plane to centreline, measurement of the degree of
stenosis. To evaluate the accuracy and reproducibility, the approach
has been applied to a vascular phantom and the results are compared
with real diameter. The results of 10 patient datasets have been
visually judged by a qualified radiologist. The results reveal the
superiority of the proposed method compared to the Conventional
thresholding Method (CTM) on both datasets.
Abstract: Quality evaluation of an image is an important task in image processing applications. In case of image compression, quality of decompressed image is also the criterion for evaluation of given coding scheme. In the process of compression -decompression various artifacts such as blocking artifacts, blur artifact, ringing or edge artifact are observed. However quantification of these artifacts is a difficult task. We propose here novel method to quantify blur and ringing artifact in an image.
Abstract: Segmentation is an important step in medical image
analysis and classification for radiological evaluation or computer
aided diagnosis. The CAD (Computer Aided Diagnosis ) of lung CT
generally first segment the area of interest (lung) and then analyze
the separately obtained area for nodule detection in order to
diagnosis the disease. For normal lung, segmentation can be
performed by making use of excellent contrast between air and
surrounding tissues. However this approach fails when lung is
affected by high density pathology. Dense pathologies are present in
approximately a fifth of clinical scans, and for computer analysis
such as detection and quantification of abnormal areas it is vital that
the entire and perfectly lung part of the image is provided and no
part, as present in the original image be eradicated. In this paper we
have proposed a lung segmentation technique which accurately
segment the lung parenchyma from lung CT Scan images. The
algorithm was tested against the 25 datasets of different patients
received from Ackron Univeristy, USA and AGA Khan Medical
University, Karachi, Pakistan.
Abstract: The risk of water erosion is one of the main
environmental concerns in the southern Mediterranean regions. Thus,
quantification of soil loss is an important issue for soil and water
conservation managers. The objective of this paper is to examine the
applicability of the Soil and Water Assessment Tool (SWAT) model
in The Sarrath river catchment, North of Tunisia, and to identify the
most vulnerable areas in order to help manager implement an
effective management program. The spatial analysis of the results
shows that 7 % of the catchment experiences very high erosion risk,
in need for suitable conservation measures to be adopted on a priority
basis. The spatial distribution of erosion risk classes estimated 3%
high, 5,4% tolerable, and 84,6% low. Among the 27 delineated subcatchments
only 4 sub-catchments are found to be under high and
very high soil loss group, two sub-catchments fell under moderate
soil loss group, whereas other sub-catchments are under low soil loss
group.
Abstract: Influence diagrams (IDs) are one of the most commonly used graphical decision models for reasoning under uncertainty. The quantification of IDs which consists in defining conditional probabilities for chance nodes and utility functions for value nodes is not always obvious. In fact, decision makers cannot always provide exact numerical values and in some cases, it is more easier for them to specify qualitative preference orders. This work proposes an adaptation of standard IDs to the qualitative framework based on possibility theory.
Abstract: A lot of research made during these last 15 years
showed that the quantification of the springback has a significant role
in the industry of sheet metal forming. These studies were made with
the objective of finding techniques and methods to minimize or
completely avoid this permanent physical variation. Moreover, the
use of steel and aluminum alloys in the car industry and aviation
poses every day the problem of the springback. The determination in
advance of the quantity of the springback allows consequently the
design and manufacture of the tool. The aim of this paper is to study
experimentally the influence of the blank holder force BHF and the
radius of curvature of the die on the springback and their influence on
the strain in various zone of specimen.
The original of our purpose consist on tests which are ensured by
adapting a U-type stretching-bending device on a tensile testing
machine, where we studied and quantified the variation of the
springback according to displacement.