Abstract: Computer aided diagnosis systems provide vital
opinion to radiologists in the detection of early signs of breast cancer
from mammogram images. Architectural distortions, masses and
microcalcifications are the major abnormalities. In this paper, a
computer aided diagnosis system has been proposed for
distinguishing abnormal mammograms with architectural distortion
from normal mammogram. Four types of texture features GLCM
texture, GLRLM texture, fractal texture and spectral texture features
for the regions of suspicion are extracted. Support vector machine
has been used as classifier in this study. The proposed system yielded
an overall sensitivity of 96.47% and an accuracy of 96% for
mammogram images collected from digital database for screening
mammography database.
Abstract: Advances in the field of image processing envision a
new era of evaluation techniques and application of procedures in
various different fields. One such field being considered is the
biomedical field for prognosis as well as diagnosis of diseases. This
plethora of methods though provides a wide range of options to select
from, it also proves confusion in selecting the apt process and also in
finding which one is more suitable. Our objective is to use a series of
techniques on bone scans, so as to detect the occurrence of
rheumatoid arthritis (RA) as accurately as possible. Amongst other
techniques existing in the field our proposed system tends to be more
effective as it depends on new methodologies that have been proved
to be better and more consistent than others. Computer aided
diagnosis will provide more accurate and infallible rate of
consistency that will help to improve the efficiency of the system.
The image first undergoes histogram smoothing and specification,
morphing operation, boundary detection by edge following algorithm
and finally image subtraction to determine the presence of
rheumatoid arthritis in a more efficient and effective way. Using preprocessing
noises are removed from images and using segmentation,
region of interest is found and Histogram smoothing is applied for a
specific portion of the images. Gray level co-occurrence matrix
(GLCM) features like Mean, Median, Energy, Correlation, Bone
Mineral Density (BMD) and etc. After finding all the features it
stores in the database. This dataset is trained with inflamed and noninflamed
values and with the help of neural network all the new
images are checked properly for their status and Rough set is
implemented for further reduction.
Abstract: Many inherited diseases and non-hereditary disorders are common in the development of renal cystic diseases. Polycystic kidney disease (PKD) is a disorder developed within the kidneys in which grouping of cysts filled with water like fluid. PKD is responsible for 5-10% of end-stage renal failure treated by dialysis or transplantation. New experimental models, application of molecular biology techniques have provided new insights into the pathogenesis of PKD. Researchers are showing keen interest for developing an automated system by applying computer aided techniques for the diagnosis of diseases. In this paper a multilayered feed forward neural network with one hidden layer is constructed, trained and tested by applying back propagation learning rule for the diagnosis of PKD based on physical symptoms and test results of urinalysis collected from the individual patients. The data collected from 50 patients are used to train and test the network. Among these samples, 75% of the data used for training and remaining 25% of the data are used for testing purpose. Further, this trained network is used to implement for new samples. The output results in normality and abnormality of the patient.
Abstract: Purpose of this work is the development of an
automatic classification system which could be useful for radiologists
in the investigation of breast cancer. The software has been designed
in the framework of the MAGIC-5 collaboration.
In the automatic classification system the suspicious regions with
high probability to include a lesion are extracted from the image as
regions of interest (ROIs). Each ROI is characterized by some
features based on morphological lesion differences.
Some classifiers as a Feed Forward Neural Network, a K-Nearest
Neighbours and a Support Vector Machine are used to distinguish the
pathological records from the healthy ones.
The results obtained in terms of sensitivity (percentage of
pathological ROIs correctly classified) and specificity (percentage of
non-pathological ROIs correctly classified) will be presented through
the Receive Operating Characteristic curve (ROC). In particular the
best performances are 88% ± 1 of area under ROC curve obtained
with the Feed Forward Neural Network.
Abstract: A typical definition of the Computer Aided Diagnosis
(CAD), found in literature, can be: A diagnosis made by a radiologist
using the output of a computerized scheme for automated image
analysis as a diagnostic aid. Often it is possible to find the expression
Computer Aided Detection (CAD or CADe): this definition
emphasizes the intent of CAD to support rather than substitute the
human observer in the analysis of radiographic images. In this article
we will illustrate the application of CAD systems and the aim of
these definitions.
Commercially available CAD systems use computerized
algorithms for identifying suspicious regions of interest. In this paper
are described the general CAD systems as an expert system
constituted of the following components: segmentation / detection,
feature extraction, and classification / decision making.
As example, in this work is shown the realization of a Computer-
Aided Detection system that is able to assist the radiologist in
identifying types of mammary tumor lesions. Furthermore this
prototype of station uses a GRID configuration to work on a large
distributed database of digitized mammographic images.
Abstract: In this research study, an intelligent detection system
to support medical diagnosis and detection of abnormal lesions by
processing endoscopic images is presented. The images used in this
study have been obtained using the M2A Swallowable Imaging
Capsule - a patented, video color-imaging disposable capsule.
Schemes have been developed to extract texture features from the
fuzzy texture spectra in the chromatic and achromatic domains for a
selected region of interest from each color component histogram of
endoscopic images. The implementation of an advanced fuzzy
inference neural network which combines fuzzy systems and
artificial neural networks and the concept of fusion of multiple
classifiers dedicated to specific feature parameters have been also
adopted in this paper. The achieved high detection accuracy of the
proposed system has provided thus an indication that such intelligent
schemes could be used as a supplementary diagnostic tool in
endoscopy.
Abstract: In this paper we address the issue of classifying the fluorescent intensity of a sample in Indirect Immuno-Fluorescence (IIF). Since IIF is a subjective, semi-quantitative test in its very nature, we discuss a strategy to reliably label the image data set by using the diagnoses performed by different physicians. Then, we discuss image pre-processing, feature extraction and selection. Finally, we propose two ANN-based classifiers that can separate intrinsically dubious samples and whose error tolerance can be flexibly set. Measured performance shows error rates less than 1%, which candidates the method to be used in daily medical practice either to perform pre-selection of cases to be examined, or to act as a second reader.
Abstract: Mammographic images and data analysis to
facilitate modelling or computer aided diagnostic (CAD) software development should best be done using a common database that can handle various mammographic image file
formats and relate these to other patient information.
This would optimize the use of the data as both primary
reporting and enhanced information extraction of research data could be performed from the single dataset. One desired
improvement is the integration of DICOM file header information into the database, as an efficient and reliable source of supplementary patient information intrinsically
available in the images.
The purpose of this paper was to design a suitable database to link and integrate different types of image files and gather common information that can be further used for research
purposes. An interface was developed for accessing, adding,
updating, modifying and extracting data from the common
database, enhancing the future possible application of the data in CAD processing.
Technically, future developments envisaged include the creation of an advanced search function to selects image files
based on descriptor combinations. Results can be further used for specific CAD processing and other research. Design of a
user friendly configuration utility for importing of the required fields from the DICOM files must be done.
Abstract: In this paper, we present user pattern learning
algorithm based MDSS (Medical Decision support system) under
ubiquitous. Most of researches are focus on hardware system, hospital
management and whole concept of ubiquitous environment even
though it is hard to implement. Our objective of this paper is to design
a MDSS framework. It helps to patient for medical treatment and
prevention of the high risk patient (COPD, heart disease, Diabetes).
This framework consist database, CAD (Computer Aided diagnosis
support system) and CAP (computer aided user vital sign prediction
system). It can be applied to develop user pattern learning algorithm
based MDSS for homecare and silver town service. Especially this
CAD has wise decision making competency. It compares current vital
sign with user-s normal condition pattern data. In addition, the CAP
computes user vital sign prediction using past data of the patient. The
novel approach is using neural network method, wireless vital sign
acquisition devices and personal computer DB system. An intelligent
agent based MDSS will help elder people and high risk patients to
prevent sudden death and disease, the physician to get the online
access to patients- data, the plan of medication service priority (e.g.
emergency case).
Abstract: Segmentation is an important step in medical image
analysis and classification for radiological evaluation or computer
aided diagnosis. This paper presents the problem of inaccurate lung
segmentation as observed in algorithms presented by researchers
working in the area of medical image analysis. The different lung
segmentation techniques have been tested using the dataset of 19
patients consisting of a total of 917 images. We obtained datasets of
11 patients from Ackron University, USA and of 8 patients from
AGA Khan Medical University, Pakistan. After testing the algorithms
against datasets, the deficiencies of each algorithm have been
highlighted.
Abstract: Segmentation is an important step in medical image
analysis and classification for radiological evaluation or computer
aided diagnosis. The CAD (Computer Aided Diagnosis ) of lung CT
generally first segment the area of interest (lung) and then analyze
the separately obtained area for nodule detection in order to
diagnosis the disease. For normal lung, segmentation can be
performed by making use of excellent contrast between air and
surrounding tissues. However this approach fails when lung is
affected by high density pathology. Dense pathologies are present in
approximately a fifth of clinical scans, and for computer analysis
such as detection and quantification of abnormal areas it is vital that
the entire and perfectly lung part of the image is provided and no
part, as present in the original image be eradicated. In this paper we
have proposed a lung segmentation technique which accurately
segment the lung parenchyma from lung CT Scan images. The
algorithm was tested against the 25 datasets of different patients
received from Ackron Univeristy, USA and AGA Khan Medical
University, Karachi, Pakistan.