Abstract: Availability of different genetic tests after completion
of Human Genome Project increases the physicians’ responsibility to
keep themselves update on the potential implementation of these
genetic tests in their daily practice. However, due to numbers of
barriers, still many of physicians are not either aware of these tests or
are not willing to offer or refer their patients for genetic tests. This
study was conducted an anonymous, cross-sectional, mailed-based
survey to develop a primary data of Malaysian physicians’ level of
knowledge and perception of gene profiling. Questionnaire had 29
questions. Total scores on selected questions were used to assess the
level of knowledge. The highest possible score was 11. Descriptive
statistics, one way ANOVA and chi-squared test was used for
statistical analysis. Sixty three completed questionnaires were
returned by 27 general practitioners (GPs) and 36 medical specialists.
Responders’ age ranges from 24 to 55 years old (mean 30.2 ± 6.4).
About 40% of the participants rated themselves as having poor level
of knowledge in genetics in general whilst 60% believed that they
have fair level of knowledge; however, almost half (46%) of the
respondents felt that they were not knowledgeable about available
genetic tests. A majority (94%) of the responders were not aware of
any lab or company which is offering gene profiling services in
Malaysia. Only 4% of participants were aware of using gene profiling
for detection of dosage of some drugs. Respondents perceived greater
utility of gene profiling for breast cancer (38%) compared to the
colorectal familial cancer (3%). The score of knowledge ranged from
2 to 8 (mean 4.38 ± 1.67). Non- significant differences between score
of knowledge of GPs and specialists were observed, with score of
4.19 and 4.58 respectively. There was no significant association
between any demographic factors and level of knowledge. However,
those who graduated between years 2001 to 2005 had higher level of
knowledge. Overall, 83% of participants showed relatively high level
of perception on value of gene profiling to detect patient’s risk of
disease. However, low perception was observed for both statements
of using gene profiling for general population in order to alter their
lifestyle (25%) as well as having the full sequence of a patient
genome for the purpose of determining a patient’s best match for
treatment (18%). The lack of clinical guidelines, limited provider
knowledge and awareness, lack of time and resources to educate
patients, lack of evidence-based clinical information and cost of tests
were the most barriers of ordering gene profiling mentioned by
physicians. In conclusion Malaysian physicians who participate in
this study had mediocre level of knowledge and awareness in gene
profiling. The low exposure to the genetic questions and problems
might be a key predictor of lack of awareness and knowledge on
available genetic tests. Educational and training workshop might be useful in helping Malaysian physicians incorporate genetic profiling
into practice for eligible patients.
Abstract: In general, codes and regulations consider seismic
loads only for completed structures of the bridges while, evaluation
of incomplete structure of bridges, especially those constructed by
free cantilever method, under these loads is also of great importance.
Hence, this research tried to study the behavior of incomplete
structure of common bridge type (box girder bridge), in construction
phase under vertical seismic loads. Subsequently, the paper provided
suitable guidelines and solutions to resist this destructive
phenomenon. Research results proved that use of preventive methods
can significantly reduce the stresses resulted from vertical seismic
loads in box cross sections to an acceptable range recommended by
design codes.
Abstract: This study aimed to examine the management and
development of forest tourism Kamchanoad. Ban Dung, Udon Thani
sustainability. Data were collected by means of qualitative research
including in-depth interviews, semi- structured, and then the data
were summarized and discussed in accordance with the objectives.
And make a presentation in the form of lectures. The target
population for the study consisted of 16 people, including
representatives from government agencies, community leaders and
the community. The results showed that Guidelines for the
Management and Development of Forest Tourism Kamchanoad
include management of buildings and infrastructure such as roads,
water, electricity, toilets. Other developments are the establishment
of a service center that provides information and resources to
facilitate tourists.; nature trails and informative signage to educate
visitors on the path to the jungle Kamchanoad; forest activities for
tourists who are interested only in occasional educational activities
such as vegetation, etc.; disseminating information on various aspects
of tourism through various channels in both Thailand and English, as
well as a web site to encourage community involvement in the
planning and management of tourism together with the care and
preservation of natural resources and preserving the local cultural
tourist area of Kamchanoad.
Abstract: In its efforts to utilize the information and
communication technology to enhance the quality of public service
delivery, national and local governments around the world are
competing to introduce more ICT applications as tools to automate
processes related to law enforcement or policy execution, increase
citizen orientation, trust, and satisfaction, and create one-stop-shops
for public services. In its implementation, e-Government ICTs need
to maintain transparency, participation, and collaboration. Due to this
diverse of mixed goals and requirements, e-Government systems
need to be designed based on special design considerations in order
to eliminate the risks of failure to compliance to government
regulations, citizen dissatisfaction, or market repulsion.
In this article we suggest a framework with guidelines for
designing government information systems that takes into
consideration the special requirements of the public sector. Then we
introduce two case studies and show how applying those guidelines
would result in a more solid system design.
Abstract: Urban Search and Rescue (USAR) is a functional
capability that has been developed to allow the United Kingdom Fire
and Rescue Service to deal with ‘major incidents’ primarily involving
structural collapse. The nature of the work undertaken by USAR
means that staying out of a damaged or collapsed building structure is
not usually an option for search and rescue personnel. As a result
there is always a risk that they themselves could become victims. For
this paper, a systematic and investigative review using desk research
was undertaken to explore the role which structural engineering can
play in assisting search and rescue personnel to conduct structural
assessments when in the field. The focus is on how search and rescue
personnel can assess damaged and collapsed building structures, not
just in terms of structural damage that may been countered, but also
in relation to structural stability. Natural disasters, accidental
emergencies, acts of terrorism and other extreme events can vary
significantly in nature and ferocity, and can cause a wide variety of
damage to building structures. It is not possible or, even realistic, to
provide search and rescue personnel with definitive guidelines and
procedures to assess damaged and collapsed building structures as
there are too many variables to consider. However, understanding
what implications damage may have upon the structural stability of a
building structure will enable search and rescue personnel to better judge
and quantify risk from a life-safety standpoint. It is intended that this
will allow search and rescue personnel to make informed decisions
and ensure every effort is made to mitigate risk, so that they
themselves do not become victims.
Abstract: There has been a significant decline in active travel
and a massive increase in the use of car dependent travel in many
countries during the past two decades. Evidential risks for people’s
physical and mental health problems are correlated with this
increased use of motorized travel. These health related problems
range from overweight and obesity to increased air pollution. In
response to these rising concerns health professionals, traffic planers,
local authorities and others have introduced a variety of initiatives to
counterbalance the dominance of cars for daily journeys.
However, the nature of travel behavior change interventions,
which aim to reduce car use, are very complex and challenging
regarding their interactions with human behavior. To change travel
behavior at least two aspects have to be taken into consideration.
First, how to alter attitudes and perceptions toward the sustainable
and healthy modes of travel, in competition with experiences of
private car use. And second, how to make these behavior change
processes irreversible and sustainable. There are no comprehensive
models available to guide policy interventions to increase the level of
success of travel behavior change interventions across both these
dimensions.
A comprehensive theoretical framework is required in the effort to
optimize how to facilitate and guide the processes of data collection
and analysis to achieve the best possible guidelines for policy
makers. Regarding the gaps in the travel behavior change research
literature, this paper attempted to identify and suggest a
multidimensional framework in order to facilitate planning the
implemented travel behavior change interventions. A structured
mixed-method model is suggested to improve the analytic power of
the results according to the complexity of human behavior.
In order to recognize people’s attitudes towards a specific travel
mode, the Theory of Planned Behavior (TPB) was operationalized.
But in order to capture decision making processes the Transtheoretical
model of Behavior Change (TTM) was also used.
Consequently, the combination of these two theories (TTM and TPB)
has resulted in a synthesis with appropriate concepts to identify and
design an implemented travel behavior change interventions.
Abstract: This paper outlines the basic installation and operation of magnetic inductive flow velocity sensors on large underground cooling water pipelines. Research on the effects of cathodic protection as well as into other factors that might influence the overall performance of the meter is presented in this paper. The experiments were carried out on an immersion type magnetic meter specially used for flow measurement of cooling water pipeline. An attempt has been made in this paper to outline guidelines that can ensure accurate measurement related to immersion type magnetic meters on underground pipelines.
Abstract: This study aims to investigate the possibility of crime
prevention through CCTV by analyzing the appropriateness of the
CCTV location, whether it is installed in the hotspot of crime-prone
areas, and exploring the crime prevention effect and transition effect.
The real crime and CCTV locations of case city were converted into
the spatial data by using GIS. The data was analyzed by hotspot
analysis and weighted displacement quotient (WDQ). As study
methods, it analyzed existing relevant studies for identifying the trends
of CCTV and crime studies based on big data from 1800 to 2014 and
understanding the relation between CCTV and crime. Second, it
investigated the current situation of nationwide CCTVs and analyzed
the guidelines of CCTV installation and operation to draw attention to
the problems and indicating points of CCTV use. Third, it investigated
the crime occurrence in case areas and the current situation of CCTV
installation in the spatial aspects, and analyzed the appropriateness and
effectiveness of CCTV installation to suggest a rational installation of
CCTV and the strategic direction of crime prevention. The results
demonstrate that there was no significant effect in the installation of
CCTV on crime prevention in the case area. This indicates that CCTV
should be installed and managed in a more scientific way reflecting
local crime situations. In terms of CCTV, the methods of spatial
analysis such as GIS, which can evaluate the installation effect, and the
methods of economic analysis like cost-benefit analysis should be
developed. In addition, these methods should be distributed to local
governments across the nation for the appropriate installation of
CCTV and operation. This study intended to find a design guideline of
the optimum CCTV installation. In this regard, this study is
meaningful in that it will contribute to the creation of a safe city.
Abstract: Precise capture of plantar 3D surface of the foot at the
loading gait phases on rigid substrates was found to be valuable for
the assessment of the physiology, health and problems of the feet.
Photogrammetry, a precision 3D spatial data capture technique is
suitable for this type of dynamic application. In this research, the
technique is utilised to study the plantar deformation as a result of
having a strip of kinesiology tape on the plantar surface during the
loading phase of gait. For this pilot study, one healthy adult male
subject was recruited under the University’s human research ethics
guidelines for this preliminary study. The 3D plantar deformation
data with and without applying the tape were analysed. The results
and analyses are presented together with detailed findings.
Abstract: Proof of controlling crack width is a basic condition
for securing suitable performance in serviceability limit state. The
cracking in concrete can occur at any time from the casting of time to
the years after the concrete has been set in place. Most codes struggle
with offering procedure for crack width calculation. There is lack in
availability of design charts for designers to compute crack width
with ease. The focus of the study is to utilize design charts and
parametric equations in calculating crack width with minimum error.
The paper contains a simplified procedure to calculate crack width
for reinforced concrete (RC) sections subjected to bending with axial
tensile force following the guidelines of Euro code [DS EN-1992-1-1
& DS EN-1992-1-2]. Numerical examples demonstrate the
application of the suggested procedure. Comparison with parallel
analytical tools supports the validity of result and show the
percentage deviation of crack width in both the procedures. The
technique is simple, user friendly and ready to evolve for a greater
spectrum of section sizes and materials.
Abstract: Nowadays, the successful implementation of ICTs is
vital for almost any kind of organization. Good governance and ICT
management are essential for delivering value, managing
technological risks, managing resources and performance
measurement. In addition, outsourcing is a strategic IT service
solution which complements IT services provided internally in
organizations. This paper proposes the measurement tools of a new
holistic maturity model based on standards ISO/IEC 20000 and
ISO/IEC 38500, and the frameworks and best practices of ITIL and
COBIT, with a specific focus on IT outsourcing. These measurement
tools allow independent validation and practical application in the
field of higher education, using a questionnaire, metrics tables, and
continuous improvement plan tables as part of the measurement
process. Guidelines and standards are proposed in the model for
facilitating adaptation to universities and achieving excellence in the
outsourcing of IT services.
Abstract: The extermination and proper disposal of
pharmaceutical wastes from expired and unused medications remains
a disputable issue due to their specific nature and characteristics.
Even though the hazards from these wastes are already well known in
terms of environment and human health, people still treat them as
usual wastes. At a national level, in many countries the management
of pharmaceutical and medical wastes has been one of the main
objectives in order to protect people’s health and the environment.
Even though many legal regulations exist in this respect, there has not
been a single law that would clearly explain the procedures of
returning medicines, ways of selection, treatment and extermination
of pharmaceutical wastes. This paper aims at analyzing the practices
of pharmaceutical waste management and treatment in some
European countries as well as a review of the legislation and official
guidelines in managing these kinds of wastes and protecting the
environment and human health. A suitable treatment and
management of expired medications and other similar wastes would
be in the interest of public health in the first place, as well as in the
interest of healthcare institutions and other bodies engaged in
environment protection.
Abstract: Inland Waterway Transportation (IWT) is playing an
important role in national transport systems, water transportation is
considered to be safe, energy efficient and environmentally friendly
mode of transport, all benefits of IWT cause national awareness
increase, for instance the Colombian government is planning to
restore the navigability of the most important river of the country, the
Magdalena’s River navigability, embrace waterway transportation in
Colombia could strength competitiveness while reduce most of the
transport externalities. However, the current situation of the
Magdalena is deplorable, the most important river of Colombia has
been abandoned for decades and the solution is beyond of a single
administrative entity. This paper analyzes the outcomes of the
Navigation And Inland Waterway Action and Development in
Europe program (NAIADES) as a prospective to develop a similar
program in Colombia with similar objectives and guidelines,
considering sustainability, guarantying the long-term future results
and adaptability of the program. Identifying stakeholders and policy
experts, a set of individual interviews were carried out; findings
support the idea of lack of integration within governmental
institutions and lack of importance in marketing promotion as
possible drawbacks on the implementation of IWT projects.
Abstract: In today’s world, the LED display has been used for
presenting visual information under various circumstances. Such
information is an important intermediary in the human information
processing. Researchers have been investigated diverse factors that
influence this process effectiveness. The letter size is undoubtedly
one major factor that has been tested and recommended by many
standards and guidelines. However, viewing information on the
display from direct perpendicular position is a typical assumption
whereas many actual events are required viewing from the angles.
This current research aims to study the effect of oblique viewing
angle and viewing distance on ability to recognize alphabet, number,
and English word. The total of ten participants was volunteered to our
3 x 4 x 4 within subject study. Independent variables include three
distance levels (2, 6, and 12 m), four oblique angles (0, 45, 60, 75
degree), and four target types (alphabet, number, short word, and
long word). Following the method of constant stimuli our study
suggests that the larger oblique angle, ranging from 0 to 75 degree
from the line of sight, results in significant higher legibility threshold
or larger font size required (p-value < 0.05). Viewing distance factor
also shows to have significant effect on the threshold (p-value
Abstract: Many quality models have been used to measure egovernment
portals quality. However, the absence of an international
consensus for e-government portals quality models results in many
differences in terms of quality attributes and measures. The aim of
this paper is to compare and analyze the existing e-government
quality models proposed in literature (those that are based on ISO
standards and those that are not) in order to propose guidelines to
build a good and useful e-government portals quality model. Our
findings show that, there is no e-government portal quality model
based on the new international standard ISO 25010. Besides that, the
quality models are not based on a best practice model to allow
agencies to both; measure e-government portals quality and identify
missing best practices for those portals.
Abstract: There are several methods to monitor software
projects and the objective for monitoring is to ensure that the
software projects are developed and delivered successfully. A
performance measurement is a method that is closely associated with
monitoring and it can be scrutinized by looking at two important
attributes which are efficiency and effectiveness both of which are
factors that are important for the success of a software project.
Consequently, a successful steering is achieved by monitoring and
controlling a software project via the performance measurement
criteria and metrics. Hence, this paper is aimed at identifying the
performance measurement criteria and the metrics for monitoring the
performance of a software project by using the Goal Question
Metrics (GQM) approach. The GQM approach is utilized to ensure
that the identified metrics are reliable and useful. These identified
metrics are useful guidelines for project managers to monitor the
performance of their software projects.
Abstract: This paper considers the characterization of a complex
electromagnetic environment due to multiple sources of
electromagnetic radiation as a five-dimensional surface which can be
described by a set of several surface sections including: instant EM
field intensity distribution maps at a given frequency and altitude,
instantaneous spectrum at a given location in space and the time
evolution of the electromagnetic field spectrum at a given point in
space. This characterization if done over time can enable the
exposure levels of Radio Frequency Radiation at every point in the
analysis area to be determined and results interpreted based on
comparison of the determined RFR exposure level with the safe
guidelines for general public exposure given by recognized body
such as the International commission on non-ionizing radiation
protection (ICNIRP), Institute of Electrical and Electronic Engineers
(IEEE), the National Radiation Protection Authority (NRPA).
Abstract: Caused by shorter product life cycles and higher
product variety the importance of production ramp ups is increasing.
Even though companies are aware of that fact, up to 40% of the ramp
up projects still miss technical and economical requirements. The
success of a ramp up depends on the planning of human factors,
organizational aspects and technological solutions. Since only partly
considered in scientific literature, this paper lays its focus on the
human factor during production ramp up. There are only incoherent
methods which address the problems in this area. A systematic and
holistic method to improve the capabilities of the employees during
ramp up is missing. The Harada Method is a relatively young
approach for developing highly-skilled workers. It consists of
different worksheets which help employees to set guidelines and
reach overall objectives. This approach is going to be transferred into
a tool for ramp up management.
Abstract: A simple, accurate and precise direct spectrophotometric method has been developed for the determination of cefixime in tablets and capsules. The method is based on the reaction of cefixime with a mixture of potassium iodide and potassium iodate to form yellow coloured product in ethanol-distilled water medium at room temperature which absorbed maximally at 352 nm. The factors affecting the reaction product were carefully studied and optimized. The validation parameters based on International Conference on Harmonisation (ICH, USA) guidelines were followed. The effect of common excipients used as additives has been tested and the tolerance limit was calculated for the determination of cefixime. Beer’s law is obeyed in the concentration range of 4 – 24 ug mL-1 with apparent molar absorptivity of 1.52 × 104 L mol-1cm-1 and Sandell’s sensitivity of 0.033 ug/cm2/ 0.001 absorbance unit. The limits of detection and quantitation for the proposed method are 0.32 and 1.06 ug mL-1, respectively. The proposed method has been successfully applied for the determination of cefixime in pharmaceutical formulations. The results obtained by the proposed method were statistically compared with the reference method using t- and F- values and found no significant difference between the two methods. The proposed method can be used as an alternate method for routine quality control analysis of cefixime in pharmaceutical formulations.
Abstract: Nowadays, the amounts of companies which tend to
have an Enterprise Resource Planning (ERP) application are
increasing. Although ERP projects are expensive, time consuming,
and complex, there are some successful experiences. These days,
developing countries are striving to implement ERP projects
successfully; however, there are many obstacles. Therefore, these
projects would be failed or partially failed. This paper concerns the
implementation of a successful ERP implementation, IFS, in Iran at
Dana Geophysics Company (DGC). After a short review of ERP and
ERP market in Iran, we propose a three phases deployment
methodology (phase 1: Preparation and Business Process
Management (BPM) phase 2: implementation and phase 3: testing,
golive-1 (pilot) and golive-2 (final)). Then, we present five guidelines
(Project Management, Change Management, Business Process
Management (BPM), Training& Knowledge Management, and
Technical Management), which were chose as work streams. In this
case study we present lessons learned in Project management and
Business process Management.