Abstract: Fresh concrete has one of dynamic properties known
as slump. Slump of concrete is design to compatible with placing
method. Due to hydration reaction of cement, the slump of concrete
is loss through time. Therefore, delayed concrete probably get reject
because slump is unacceptable. In order to recover the slump of
delayed concrete the second dose of superplasticizer (naphthalene
based type F) is added into the system, the slump recovery can be
done as long as the concrete is not setting. By adding superplasticizer
as solution for recover unusable slump loss concrete may affects
other concrete properties. Therefore, this paper was observed setting
times and compressive strength of concrete after being re-dose with
chemical admixture type F (superplasticizer, naphthalene based) for
slump recovery. The concrete used in this study was fly ash concrete
with fly ash replacement of 0%, 30% and 50% respectively. Concrete
mix designed for test specimen was prepared with paste content (ratio
of volume of cement to volume of void in the aggregate) of 1.2 and
1.3, water-to-binder ratio (w/b) range of 0.3 to 0.58, initial dose of
superplasticizer (SP) range from 0.5 to 1.6%. The setting times of
concrete were tested both before and after re-dosed with different
amount of second dose and time of dosing. The research was
concluded that addition of second dose of superplasticizer would
increase both initial and final setting times accordingly to dosage of
addition. As for fly ash concrete, the prolongation effect was higher
as the replacement of fly ash increase. The prolongation effect can
reach up to maximum about 4 hours. In case of compressive strength,
the re-dosed concrete has strength fluctuation within acceptable range
of ±10%.
Abstract: This paper aimed to introduce the solution of concrete
slump recovery using chemical admixture type-F (superplasticizer,
naphthalene base) to the practice in order to solve unusable concrete
problem due to concrete loss its slump, especially for those tropical
countries that have faster slump loss rate. In the other hand, randomly
adding superplasticizer into concrete can cause concrete to segregate.
Therefore, this paper also develops the estimation model used to
calculate amount of second dose of superplasticizer need for concrete
slump recovery. Fresh properties of ordinary Portland cement
concrete with volumetric ratio of paste to void between aggregate
(paste content) of 1.1-1.3 with water-cement ratio zone of 0.30 to
0.67 and initial superplasticizer (naphthalene base) of 0.25%-1.6%
were tested for initial slump and slump loss for every 30 minutes for
one and half hour by slump cone test. Those concretes with slump
loss range from 10% to 90% were re-dosed and successfully
recovered back to its initial slump. Slump after re-dosed was tested
by slump cone test. From the result, it has been concluded that, slump
loss was slower for those mix with high initial dose of
superplasticizer due to addition of superplasticizer will disturb
cement hydration. The required second dose of superplasticizer was
affected by two major parameters, which were water-cement ratio
and paste content, where lower water-cement ratio and paste content
cause an increase in require second dose of superplasticizer. The
amount of second dose of superplasticizer is higher as the solid
content within the system is increase, solid can be either from cement
particles or aggregate. The data was analyzed to form an equation use
to estimate the amount of second dosage requirement of
superplasticizer to recovery slump to its original.
Abstract: This study evaluated the acute toxicity and tissue
distribution of intravenously administered gold nanoparticles
(AuNPs) in male rabbits. Rabbits were exposed to single dose of
AuNPs (300 μg/ kg). Toxic effects were assessed via general
behavior, hematological parameters, serum biochemical parameters,
and histopathological examination of various rabbits’ organs.
Inductively coupled plasma–mass spectrometry (ICP-MS) was used
to determine gold concentrations in tissue samples collected at
predetermined time intervals. After one week, AuNPs exerted no
obvious acute toxicity in rabbits. However, inflammatory reactions
were observed in liver, lungs and kidneys accompanied with mild
absolute neutrophilia and significant monocytosis. The highest gold
levels were found in the spleen and liver followed by lungs, and
kidneys. These results indicated that AuNPs could be distributed
extensively to various tissues in the body, but primarily in the spleen
and liver.
Abstract: Many herbal medicinal products are considered
potential anti-hypercholesterolemic agents with encouraging safety
profiles, however only a limited amount of clinical research exists to
support their efficacy. The present study was designed to compare the
antihypercholesterolemic and antioxidant activities of the crude
ethanolic extracts of Citrus reticulata fruit peel, Zingiber officinale
rhizome and Sesamum indicum seeds. Forty-five rats were used throughout the experiment which are
extended for four weeks. These were divided into nine groups, five
rats per each group as follows; group 1 was the normal control group
(rats only fed standard normal rat diet), group 2 was the
hypercholesterolemic control group (rats fed only
hypercholesterolemic diet which contained 1% cholesterol plus 10%
saturated animal fat added to the normal rat diet), groups 3 and 4
were fed hypercholesterolemic diet in addition to Citrus reticulata
ethanolic extract at doses of (250mg/kg (group 3) and 500mg/kg
(group 4)) administered daily via oral route, groups 5 and 6 were
given hypercholesterolemic diet in addition to Zingiber officinale
ethanolic extract at doses of (250mg/kg (group 5) and 500mg/kg
(group 6)) daily through oral route, groups 7 and 8 fed on
hypercholesterolemic diet in addition to Sesamum indicum ethanolic
extract at doses of (250mg/kg (group 7) and 500mg/kg (group 8))
daily orally; and group 9 rats were given hypercholesterolemic diet in
addition to atorvastatin (0.18mg/kg) daily via oral route as a standard
reference antihypercholesterolemic drug. Blood samples from all
groups were drawn from the retro-orbital venous plexus four weeks
following treatment after overnight fasting and the lipid profile (total
cholesterol (TC), high density lipoprotein-cholesterol (HDL-C), low
density lipoprotein-cholesterol (LDL-C) and triglyceride levels) were
measured and the risk ratio (TC/HDL-C) was assessed. The
antioxidant activity of the three plants extracts was determined using
DPPH free-radical antioxidant assay. Results of in vivo and in vitro
antihypercholesterolemic and antioxidant assay respectively, revealed
that the three extracts possess comparable antioxidant and
antihypercholesterolemic activities.
Abstract: An early diagnosis of bone metastasis is very
important for making a right decision on a subsequent therapy. One
of the most important steps to be taken initially, for developing a new
radiopharmaceutical is the measurement of organ radiation exposure
dose. In this study, the dosimetric studies of a novel agent for
SPECT-imaging of the bone metastasis, 111In-(4-
{[(bis(phosphonomethyl))carbamoyl]methyl}7,10bis(carboxymethyl)
-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (111In-BPAMD)
complex, have been carried out to estimate the dose in human organs
based on the data derived from mice. The radiolabeled complex was
prepared with high radiochemical purity in the optimal conditions.
Biodistribution studies of the complex was investigated in the male
Syrian mice at the selected times after injection (2, 4, 24 and 48 h).
The human absorbed dose estimation of the complex was made based
on data derived from the mice by the radiation absorbed dose
assessment resource (RADAR) method. 111In-BPAMD complex was prepared with high radiochemical
purity >95% (ITLC) and specific activities of 2.85 TBq/mmol. Total
body effective absorbed dose for 111In-BPAMD was 0.205
mSv/MBq. This value is comparable to the other 111In clinically used
complexes. The results show that the dose with respect to the critical
organs is satisfactory within the acceptable range for diagnostic
nuclear medicine procedures. Generally, 111In-BPAMD has
interesting characteristics and it can be considered as a viable agent
for SPECT-imaging of the bone metastasis in the near future.
Abstract: Abstract—[Tris (1,10-phenanthroline) lanthanum(III)]
trithiocyanate is a new compound that has shown high ability for
stopping the synthesis of DNA and also acting as a photosensitizer.
Nowadays, the radiation dose assessment resource (RADAR) method
is known as the most common method for absorbed dose calculation.
177Lu was produced by (n, gamma) reaction in a research reactor.
177Lu-PL3 was prepared in the optimized condition. The
radiochemical yield was checked by ITLC method. The
biodistribution of the complex was investigated by intravenously
injection to wild-type rats via their tail veins. In this study, the
absorbed dose of 177Lu-PL3 to human organs was estimated by
RADAR method. 177Lu was prepared with a specific activity of 2.6-3
GBq.mg-1 and radionuclide purity of 99.98 %. Final preparation of
the radiolabelled complex showed high radiochemical purity of >
99%. The results show that liver and spleen have received the highest
absorbed dose of 1.051 and 0.441 mSv/MBq, respectively. The
absorbed dose values for these two dose-limiting tissues suggest
more biological studies special in tumor-bearing animals.
Abstract: The measurement of organ radiation exposure dose is
one of the most important steps to be taken initially, for developing a
new radiopharmaceutical. In this study, the dosimetric studies of a
novel agent for SPECT-imaging of the bone metastasis, 111In-
1,4,7,10-tetraazacyclododecane-1,4,7,10 tetraethylene phosphonic
acid (111In-DOTMP) complex, have been carried out to estimate the
dose in human organs based on the data derived from rats. The
radiolabeled complex was prepared with high radiochemical purity in
the optimal conditions. Biodistribution studies of the complex was
investigated in the male Syrian rats at selected times after injection
(2, 4, 24 and 48 h). The human absorbed dose estimation of the
complex was made based on data derived from the rats by the
radiation absorbed dose assessment resource (RADAR) method.
111In-DOTMP complex was prepared with high radiochemical purity
of >99% (ITLC). Total body effective absorbed dose for 111In-
DOTMP was 0.061 mSv/MBq. This value is comparable to the other
111In clinically used complexes. The results show that the dose with
respect to the critical organs is satisfactory within the acceptable
range for diagnostic nuclear medicine procedures. Generally, 111In-
DOTMP has interesting characteristics and can be considered as a
viable agent for SPECT-imaging of the bone metastasis in the near
future.
Abstract: Red pepper (Capsicum annum L.) has long been
recognized as a good source of antioxidants, being rich in ascorbic
acid and other phytochemicals. In Turkish cuisine red pepper is
sometimes consumed raw in salads and baked as a garnish, but its
most wide consumption type is red pepper paste. The processing of
red pepper into pepper paste includes various thermal treatment steps
such as heating and pasteurizing. There are reports demonstrating an
enhancement or reduction in antioxidant activity of vegetables after
thermal treatment. So this study was conducted to investigate the
total phenolic, ascorbic acid and total carotenoids as well as free
radical scavenging activity of raw red pepper and various red pepper
pastes obtainable on the market. The samples were analyzed for
radical-scavenging activity (RSA) and total polyphenol (TP) content
using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and Folin-Ciocalteu
methods, respectively. Total carotenoids and ascorbic acid contents
were determined spectrophotometrically. Results suggest that hot
pepper paste contained significantly (P0.05) difference in RSA, ascorbic acid and total carotenoids
content between sweet and hot red pepper paste products. It is
concluded that the red pepper paste, that has a wide range of
consumption in Turkish cuisine, presents a good dose of phenolic
compounds and antioxidant capacity and it should be regarded as a
functional food.
Abstract: Tannins are a unique category of plant phytochemicals
especially in terms of their vast potential health-benefiting properties.
Researchers have described the capacity of tannins to enhance
glucose uptake and inhibit adipogenesis, thus being potential drugs
for the treatment of non-insulin dependent diabetes mellitus. Thus,
the present research was conducted to find out tannin content of food
products. The percentage of tannin in various analyzed sources
ranged from 0.0 to 108.53%; highest in kathaa and lowest in ker and
mango bark. The percentage of tannins present in the plants,
however, varies. Numerous studies have confirmed that the naturally
occurring polyphenols are key factor for the beneficial effects of the
herbal medicines. Isolation and identification of active constituents
from plants, preparation of standardized dose & dosage regimen can
play a significant role in improving the hypoglycaemic action.
Abstract: One of the most important challenging factors in
medical images is nominated as noise. Image denoising refers to the
improvement of a digital medical image that has been infected by
Additive White Gaussian Noise (AWGN). The digital medical image
or video can be affected by different types of noises. They are
impulse noise, Poisson noise and AWGN. Computed tomography
(CT) images are subjects to low quality due to the noise. Quality of
CT images is dependent on absorbed dose to patients directly in such
a way that increase in absorbed radiation, consequently absorbed
dose to patients (ADP), enhances the CT images quality. In this
manner, noise reduction techniques on purpose of images quality
enhancement exposing no excess radiation to patients is one the
challenging problems for CT images processing. In this work, noise
reduction in CT images was performed using two different
directional 2 dimensional (2D) transformations; i.e., Curvelet and
Contourlet and Discrete Wavelet Transform (DWT) thresholding
methods of BayesShrink and AdaptShrink, compared to each other
and we proposed a new threshold in wavelet domain for not only
noise reduction but also edge retaining, consequently the proposed
method retains the modified coefficients significantly that result good
visual quality. Data evaluations were accomplished by using two
criterions; namely, peak signal to noise ratio (PSNR) and Structure
similarity (Ssim).
Abstract: A multilayer passive shield composed of low-activity
lead (Pb), copper (Cu), tin (Sn) and iron (Fe) was designed and
manufactured for a coaxial HPGe detector placed at a surface
laboratory for reducing background radiation and radiation dose to
the personnel. The performance of the shield was evaluated and
efficiency curves of the detector were plotted by using of various
standard sources in different distances. Monte Carlo simulations and
a set of TLD chips were used for dose estimation in two distances of
20 and 40 cm. The results show that the shield reduced background
spectrum and the personnel dose more than 95%.
Abstract: The phytotoxicity of heavy metals can be expressed
on roots and visible part of plants and is characterized by molecular
and metabolic answers at various levels of organization of the whole
plant. The present study was undertaken on two varieties of broad
bean Vicia faba (Sidi Aïch and Super Aguadulce). The device was
mounted on a substrate prepared by mixing sand, soil and compost,
the substrate was artificially contaminated with three doses of lead
nitrate [Pb(NO3)2] 0, 500 and 1000 ppm. Our objective is to follow
the behavior of plant opposite the stress by evaluating the
physiological parameters. The results reveal a reduction in the
parameters of the productivity (chlorophyll and proteins production)
with an increase in the osmoregulators (soluble sugars and
proline).These results show that the production of broad bean is
strongly modified by the disturbance of its internal physiology under
lead exposure.
Abstract: The use of engineered nanomaterials has increased as
a result of their positive impact on many sectors of the economy,
including agriculture. Silver nanoparticles (AgNPs) are now used to
enhance seed germination, plant growth, and photosynthetic quantum
efficiency and as antimicrobial agents to control plant diseases. In
this study, we examined the effect of AgNP dosage on the seed
germination of three plant species: corn (Zea mays L.), watermelon
(Citrullus lanatus [Thunb.] Matsum. & Nakai) and zucchini
(Cucurbita pepo L.). This experiment was designed to study the
effect of AgNPs on germination percentage, germination rate, mean
germination time, root length and fresh and dry weight of seedlings
for the three species. Seven concentrations (0.05, 0.1, 0.5, 1, 1.5, 2
and 2.5 mg/ml) of AgNPs were examined at the seed germination
stage. The three species had different dose responses to AgNPs in
terms of germination parameters and the measured growth
characteristics. The germination rates of the three plants were
enhanced in response to AgNPs. Significant enhancement of the
germination percentage values was observed after treatment of the
watermelon and zucchini plants with AgNPs in comparison with
untreated seeds. AgNPs showed a toxic effect on corn root
elongation, whereas watermelon and zucchini seedling growth were
positively affected by certain concentrations of AgNPs. This study
showed that exposure to AgNPs caused both positive and negative
effects on plant growth and germination.
Abstract: In this study, breeding biology and induced breeding
of freshwater mud eel, Monopterus cuchia was observed during the
experimental period from February to June, 2013. Breeding biology
of freshwater mud eel, Monopterus cuchia was considered in terms of
gonadosomatic index, length-weight relationship of gonad, ova
diameter and fecundity. The ova diameter was recorded from 0.3 mm
to 4.30 mm and the individual fecundity was recorded from 155 to
1495 while relative fecundity was found from 2.64 to 12.45. The
fecundity related to body weight and length of fish was also
discussed. A peak of GSI was observed 2.14±0.2 in male and 5.1
±1.09 in female. Induced breeding of freshwater mud eel,
Monopterus cuchia was also practiced with different doses of
different inducing agents like pituitary gland (PG), human chorionic
gonadotropin (HCG), Gonadotropin releasing hormone (GnRH) and
Ovuline-a synthetic hormone in different environmental conditions.
However, it was observed that the artificial breeding of freshwater
mud eel, Monopterus cuchia was not yet succeeded through inducing
agents in captive conditions, rather the inducing agent showed
negative impacts on fecundity and ovarian tissues. It was seen that
mature eggs in the oviduct were reduced, absorbed and some eggs
were found in spoiled condition.
Abstract: In the immunologic sense, clinical infection is a state
of failure of the immune system to combat the pathogenic weapon of
the bacteria invading the host. A motile gram negative vibroid
organism associated with marked mono and poly nuclear cell
responses was traced during the examination of a clinical material
from an infected common carp Cyprinus carpio. On primary plate
culture, growth was shown to be pure, dense population of an
Aeromonas-like colony morphotype. The pure isolate was found to
be; Aerobic, facultatively anaerobic, non-halophilic, grew at 0C, and
37C, oxidase positive utilizes glucose through fermentative pathway,
resist 0/129 and novobiocin, produces alanine and lysine
decarboxylases but non-producing ornithine dehydrolases. Tests for
the in vitro determinants of pathogenicity has shown to be; Betahaemolytic
onto blood agar, gelatinase, casienase and amylase
producer. Three in vivo determinants of pathogenicity were tested as,
the lethal dose fifty, the pathogenesis and pathogenicity. It was
evident that 0.1 milliliter of the causal bacterial cell suspension of a
density 1 x 107 CFU/ml injected intramuscularly into an average of
100gms fish toke five days incubation period, then at the day six
morbidity and mortality were initiated. LD50 was recorded at the day
12 post-infection. Use of an LD50 doses to study the pathogenicity,
reveals mononuclear and polynuclear cell responses, on examining
the stained direct films of the clinical materials from the
experimentally infected fish. Re-isolation tests confirm that the reisolant
is same. The course of the infection in natural case was shown
manifestation of; skin ulceration, haemorrhage and descaling. On
evisceration, the internal organs were shown; congestion in the
intestines, spleen and, air sacs. The induced infection showed a
milder form of these manifestations. The grading of the virulence of
this organism was virulent causing chronic course of infections as
indicated from the pathogenesis and pathogenicity studies. Thus the
infectious bacteria were consistent with Aeromonas hydrophila, and
the infection was chronic.
Abstract: The addition of lime as Ca(OH)2 to sewage sludge to
destroy pathogens (Escherichia coli), was evaluated also in relation
to heavy metal bioavailability.
The obtained results show that the use of calcium hydroxide at the
dose of 3% effectively destroyed pathogens ensuring the stability at
high pH values over long period and the duration of the sewage
sludge stabilization. In general, lime addition decreased the total
extractability of heavy metals indicating a reduced bioavailability of
these elements. This is particularly important for a safe utilization in
agricultural soils to reduce the possible transfer of heavy metals to
the food chain.
Abstract: Quantitative radiobiological models can be used to
assess the optimum clinical outcome from sophisticated therapeutic
modalities by calculating tumor control probability (TCP) and normal
tissue complication probability (NTCP). In this study two 3D-CRT
and an IMRT treatment plans were developed with an initial
prescription dose of 60 Gy in 2 Gy/fraction to prostate. Sensitivity of
TCP and Complication free tumor control probability (P+) to the
different values of α/β ratio was investigated for various prescription
doses planned to be delivered in either a fixed number of fractions (I)
or in a fixed dose per fraction (II) in each of the three different
treatment plans. High dose/fraction and high α/β value result in
comparatively smaller P+ and IMRT plans resulted in the highest P+,
mainly due to the decrease in NTCP. If α/β is lower than expected,
better tumor control can be achieved by increasing dose/fraction but
decreasing the number of fractions.
Abstract: Many industrial materials like magnets need to be
tested for the radiation environment expected at linear colliders (LC)
where the accelerator and detectors will be subjected to large
influences of beta, neutron and gamma’s over their life Gamma
irradiation of the permanent sample magnets using a 60Co source was
investigated up to an absorbed dose of 700Mrad shows a negligible
effect on some magnetic properties of Nd-Fe-B. In this work it has
been tried to investigate the change of some important properties of
Barium hexa ferrite. Results showed little decreases of magnetic
properties at doses rang of 0.5 to 2.5 Mrad. But at the gamma
irradiation dose up to 10 Mrad it is showed a few increase of
properties. Also study of gamma irradiation of Nd-Fe-B showed
considerably increase of magnetic properties.
Abstract: The use of engineered nanomaterials has increased as
a result of their positive impact on many sectors of the economy,
including agriculture. Silver nanoparticles (AgNPs) are now used to
enhance seed germination, plant growth, and photosynthetic quantum
efficiency and as antimicrobial agents to control plant diseases. In
this study, we examined the effect of AgNP dosage on the seed
germination of three plant species: corn (Zea mays L.), watermelon
(Citrullus lanatus [Thunb.] Matsum. & Nakai) and zucchini
(Cucurbita pepo L.). This experiment was designed to study the
effect of AgNPs on germination percentage, germination rate, mean
germination time, root length and fresh and dry weight of seedlings
for the three species. Seven concentrations (0.05, 0.1, 0.5, 1, 1.5, 2
and 2.5 mg/ml) of AgNPs were examined at the seed germination
stage. The three species had different dose responses to AgNPs in
terms of germination parameters and the measured growth
characteristics. The germination rates of the three plants were
enhanced in response to AgNPs. Significant enhancement of the
germination percentage values was observed after treatment of the
watermelon and zucchini plants with AgNPs in comparison with
untreated seeds. AgNPs showed a toxic effect on corn root
elongation, whereas watermelon and zucchini seedling growth were
positively affected by certain concentrations of AgNPs. This study
showed that exposure to AgNPs caused both positive and negative
effects on plant growth and germination.
Abstract: The potential neuroprotective effect of Phyllantus
nuriri against Fe2+ and sodium nitroprusside (SNP) induced oxidative
stress in mitochondria of rats brain was evaluated. Cellular viability
was assessed by MTT reduction, reactive oxygen species (ROS)
generation was measured using the probe 2,7-dichlorofluoresce
indiacetate (DCFH-DA). Glutathione content was measured using
dithionitrobenzoic acid (DTNB). Fe2+ (10μM) and SNP (5μM)
significantly decreased mitochondrial activity, assessed by MTT
reduction assay, in a dose-dependent manner, this occurred in parallel
with increased glutathione oxidation, ROS production and lipid
peroxidation end-products (thiobarbituric acid reactive substances,
TBARS). The co-incubation with methanolic extract of Phyllantus
nuriri (10-200 μg/ml) reduced the disruption of mitochondrial
activity, gluthathione oxidation, ROS production as well as the
increase in TBARS levels caused by both Fe2+ and SNP in a dose
dependent manner. HPLC analysis of the extract revealed the
presence of gallic acid (20.540.01), caffeic acid (7.930.02), rutin
(25.310.05), quercetin (31.280.03) and kaemferol (14.360.01).
This result suggests that these phytochemicals account for the
protective actions of P. niruri against Fe2+ and SNP -induced
oxidative stress. Our results show that P. nuriri consist important
bioactive molecules in the search for an improved therapy against the
deleterious effects of Fe2+, an intrinsic producer of reactive oxygen
species (ROS), that leads to neuronal oxidative stress and
neurodegeneration.