Abstract: A bio-sensing method, based on the plasmonic property of gold nano-islands, has been developed for detection of exosomes in a clinical setting. The position of the gold plasmon band in the UV-Visible spectrum depends on the size and shape of gold nanoparticles as well as on the surrounding environment. By adsorbing various chemical entities, or binding them, the gold plasmon band will shift toward longer wavelengths and the shift is proportional to the concentration. Exosomes transport cargoes of molecules and genetic materials to proximal and distal cells. Presently, the standard method for their isolation and quantification from body fluids is by ultracentrifugation, not a practical method to be implemented in a clinical setting. Thus, a versatile and cutting-edge platform is required to selectively detect and isolate exosomes for further analysis at clinical level. The new sensing protocol, instead of antibodies, makes use of a specially synthesized polypeptide (Vn96), to capture and quantify the exosomes from different media, by binding the heat shock proteins from exosomes. The protocol has been established and optimized by using a glass substrate, in order to facilitate the next stage, namely the transfer of the protocol to a microfluidic environment. After each step of the protocol, the UV-Vis spectrum was recorded and the position of gold Localized Surface Plasmon Resonance (LSPR) band was measured. The sensing process was modelled, taking into account the characteristics of the nano-island structure, prepared by thermal convection and annealing. The optimal molar ratios of the most important chemical entities, involved in the detection of exosomes were calculated as well. Indeed, it was found that the results of the sensing process depend on the two major steps: the molar ratios of streptavidin to biotin-PEG-Vn96 and, the final step, the capture of exosomes by the biotin-PEG-Vn96 complex. The microfluidic device designed for sensing of exosomes consists of a glass substrate, sealed by a PDMS layer that contains the channel and a collecting chamber. In the device, the solutions of linker, cross-linker, etc., are pumped over the gold nano-islands and an Ocean Optics spectrometer is used to measure the position of the Au plasmon band at each step of the sensing. The experiments have shown that the shift of the Au LSPR band is proportional to the concentration of exosomes and, thereby, exosomes can be accurately quantified. An important advantage of the method is the ability to discriminate between exosomes having different origins.
Abstract: Non-specific chronic low back pain (NSCLBP) is a common condition with no exact diagnosis and mechanism for its occurrence. Recently, different therapeutic exercises have taken into account to manage NSCLBP. So, the aim of this study has mainly been placed on comparing the effects of Pilates and Mackenzie exercises on quality of life (QOL) lumbar spine position sense (LSPS) in patients with NSCLBP. In this randomized clinical trial, 47 patients with NSCLBP were voluntarily divided into three groups of Pilates (n=16) (with mean age 37.1 ± 9.5 years, height 168.9 ± 7.4 cm, body mass 76.1 ± 5.9 k), McKenzie (n=15) (with mean age 42.7 ± 8.1 years, height 165.7 ± 6.8, body mass 74.1 ± 4.8 kg) and control (n=16) (with mean age 39.3 ± 9.8 years, height 168.1 ± 8.1 cm, body mass 74.2 ± 5.8 kg). Primary outcome included QOL and secondary was LSPS. Both variables were assessed by the WHOQOL-BREF questionnaires and electrogoniameter, respectively. The measurements were performed at baseline, following a 6-week intervention, and after a 4-week follow-up. The ANCOVA test at P < 0.05 was administrated to analyze the collected data using SPSS software. There was a statistically significant difference between experimental groups and the control group to improve QOL. But, no difference was seen regarding the effects of two exercises on LSPS (p < 0.05). Both Pilates and Mackenzie exercises demonstrated improvement in QOL after 6-week intervention and a 4-week follow-up while none of them considerably affected LSPS. Further studies are required to establish a supporting evidence for the effectiveness of two exercises on NSCLBP.
Abstract: Seamless modification of an entity for the purpose of hiding a message of significance inside its substance in a manner that the embedding remains oblivious to an observer is known as steganography. Together with today's pervasive registering frameworks, steganography has developed into a science that offers an assortment of strategies for stealth correspondence over the globe that must, however, need a critical appraisal from security breach standpoint. Microsoft Word is amongst the preferably used word processing software, which comes as a part of the Microsoft Office suite. With a user-friendly graphical interface, the richness of text editing, and formatting topographies, the documents produced through this software are also most suitable for stealth communication. This research aimed not only to epitomize the fundamental concepts of steganography but also to expound on the utilization of Microsoft Word document as a carrier for furtive message exchange. The exertion is to examine contemporary message hiding schemes from security aspect so as to present the explorative discoveries and suggest enhancements which may serve a wellspring of information to encourage such futuristic research endeavors.
Abstract: A large-scale power system (LSPS) consists of two
or more sub-systems connected by inter-connecting transmission.
Loading pattern on an LSPS always changes from time to time and
varies depend on consumer need. The serious instability problem is
appeared in an LSPS due to load fluctuation in all of the bus. Adaptive
neuro-fuzzy inference system (ANFIS)-based power system stabilizer
(PSS) is presented to cover the stability problem and to enhance
the stability of an LSPS. The ANFIS control is presented because
the ANFIS control is more effective than Mamdani fuzzy control in
the computation aspect. Simulation results show that the presented
PSS is able to maintain the stability by decreasing peak overshoot
to the value of −2.56 × 10−5 pu for rotor speed deviation Δω2−3.
The presented PSS also makes the settling time to achieve at 3.78
s on local mode oscillation. Furthermore, the presented PSS is able
to improve the peak overshoot and settling time of Δω3−9 to the
value of −0.868 × 10−5 pu and at the time of 3.50 s for inter-area
oscillation.
Abstract: We present in this work our model of road traffic
emissions (line sources) and dispersion of these emissions, named
DISPOLSPEM (Dispersion of Poly Sources and Pollutants Emission
Model). In its emission part, this model was designed to keep the
consistent bottom-up and top-down approaches. It also allows to
generate emission inventories from reduced input parameters being
adapted to existing conditions in Morocco and in the other developing
countries. While several simplifications are made, all the performance
of the model results are kept. A further important advantage of
the model is that it allows the uncertainty calculation and emission
rate uncertainty according to each of the input parameters. In the
dispersion part of the model, an improved line source model has
been developed, implemented and tested against a reference solution.
It provides improvement in accuracy over previous formulas of line
source Gaussian plume model, without being too demanding in terms
of computational resources. In the case study presented here, the
biggest errors were associated with the ends of line source sections;
these errors will be canceled by adjacent sections of line sources
during the simulation of a road network. In cases where the wind
is parallel to the source line, the use of the combination discretized
source and analytical line source formulas minimizes remarkably the
error. Because this combination is applied only for a small number
of wind directions, it should not excessively increase the calculation
time.
Abstract: 21st century has transformed the labor market
landscape in a way of posing new and different demands on
university graduates as well as university lecturers, which means that
the knowledge and academic skills students acquire in the course of
their studies should be applicable and transferable from the higher
education context to their future professional careers. Given the
context of the Languages for Specific Purposes (LSP) classroom, the
teachers’ objective is not only to teach the language itself, but also to
prepare students to use that language as a medium to develop generic
skills and competences. These include media and information
literacy, critical and creative thinking, problem-solving and analytical
skills, effective written and oral communication, as well as
collaborative work and social skills, all of which are necessary to
make university graduates more competitive in everyday professional
environments. On the other hand, due to limitations of time and large
numbers of students in classes, the frequently topic-centered syllabus
of LSP courses places considerable focus on acquiring the subject
matter and specialist vocabulary instead of sufficient development of
skills and competences required by students’ prospective employers.
This paper intends to explore some of those issues as viewed both by
LSP lecturers and by business professionals in their respective
surveys. The surveys were conducted among more than 50 LSP
lecturers at higher education institutions in Croatia, more than 40 HR
professionals and more than 60 university graduates with degrees in
economics and/or business working in management positions in
mainly large and medium-sized companies in Croatia. Various elements of LSP course content have been taken into
consideration in this research, including reading and listening
comprehension of specialist texts, acquisition of specialist vocabulary
and grammatical structures, as well as presentation and negotiation
skills. The ability to hold meetings, conduct business correspondence,
write reports, academic texts, case studies and take part in debates
were also taken into consideration, as well as informal business
communication, business etiquette and core courses delivered in a
foreign language. The results of the surveys conducted among LSP
lecturers will be analyzed with reference to what extent those
elements are included in their courses and how consistently and
thoroughly they are evaluated according to their course requirements.
Their opinions will be compared to the results of the surveys
conducted among professionals from a range of industries in Croatia
so as to examine how useful and important they perceive the same
elements of the LSP course content in their working environments.
Such comparative analysis will thus show to what extent the syllabi
of LSP courses meet the demands of the employment market when it
comes to the students’ language skills and competences, as well as
transferable skills. Finally, the findings will also be compared to the
observations based on practical teaching experience and the relevant
sources that have been used in this research. In conclusion, the ideas and observations in this paper are merely
open-ended questions that do not have conclusive answers, but might
prompt LSP lecturers to re-evaluate the content and objectives of
their course syllabi.
Abstract: This paper presents the design process of a high
performance 3-phase 3.7 kW 2-pole line start permanent magnet
synchronous motor for pumping system. A method was proposed to
study the starting torque characteristics considering line start with
high inertia load. A d-q model including cage was built to study the
synchronization capability. Time-stepping finite element method
analysis was utilized to accurately predict the dynamic and transient
performance, efficiency, starting current, speed curve and etc.
Considering the load torque of pumps during starting stage, the rotor
bar was designed with minimum demagnetization of permanent
magnet caused by huge starting current.
Abstract: The Economic Lot Scheduling Problem (ELSP) is a
valuable mathematical model that can support decision-makers to
make scheduling decisions. The basic period approach is effective for
solving the ELSP. The assumption for applying the basic period
approach is that a product must use its maximum production rate to be
produced. However, a product can lower its production rate to reduce
the average total cost when a facility has extra idle time. The past
researches discussed how a product adjusts its production rate under
the common cycle approach. To the best of our knowledge, no studies
have addressed how a product lowers its production rate under the
basic period approach. This research is the first paper to discuss this
topic. The research develops a simple fixed rate approach that adjusts
the production rate of a product under the basic period approach to
solve the ELSP. Our numerical example shows our approach can find a
better solution than the traditional basic period approach. Our
mathematical model that applies the fixed rate approach under the
basic period approach can serve as a reference for other related
researches.
Abstract: We investigate relaxation dynamics of a quantum
dipole emitter (QDE), e.g., a molecule or quantum dot, located near a
metal nanoparticle (MNP) exhibiting a dipolar localized surface
plasmon (LSP) resonance at the frequency of the QDE radiative
transition. It is shown that under the condition of the QDE-MNP
characteristic relaxation time being much shorter than that of the
QDE in free-space but much longer than the LSP lifetime. It is also
shown that energy dissipation in the QDE-MNP system is relatively
weak with the probability of the photon emission being about 0.75, a
number which, rather surprisingly, does not explicitly depend on the
metal absorption characteristics. The degree of entanglement
measured by the concurrency takes the maximum value, while the
distances between the QDEs and metal ball approximately are equal.
Abstract: Semiconductor crystals smaller than about 10 nm,
known as quantum dots, have properties that differ from large
samples, including a band gap that becomes larger for smaller
particles. These properties create several applications for quantum
dots. In this paper new shapes of quantum dot arrays are used to
enhance the photo physical properties of gold nano-particles. This
paper presents a study of the effect of nano-particles shape, array, and
size on their absorption characteristics.
Abstract: In the context of large volume Big Divisor (nearly)
SLagy D3/D7 μ-Split SUSY [1], after an explicit identification
of first generation of SM leptons and quarks with fermionic superpartners
of four Wilson line moduli, we discuss the identification of
gravitino as a potential dark matter candidate by explicitly calculating
the decay life times of gravitino (LSP) to be greater than age of
universe and lifetimes of decays of the co-NLSPs (the first generation
squark/slepton and a neutralino) to the LSP (the gravitino) to be
very small to respect BBN constraints. Interested in non-thermal
production mechanism of gravitino, we evaluate the relic abundance
of gravitino LSP in terms of that of the co-NLSP-s by evaluating
their (co-)annihilation cross sections and hence show that the former
satisfies the requirement for a potential Dark Matter candidate. We
also show that it is possible to obtain a 125 GeV light Higgs in our
setup.
Abstract: Article is devoted to the problem of Kazakhstan people national values in the conditions of the Republic of Kazakhstan independence. Formation of ethnos national values is viewed as the mandatory constituent of this process in contemporary conditions. The article shows the dynamics of forming socialspiritual basis of Kazakhstan people-s national values. It depicts peculiarities of interethnic relations in poly-ethnic and multiconfessional Kazakhstan. The study reviews in every detail various directions of the state social policy development in the sphere of national values. It is aimed to consolidation of the society to achieve the shared objective, i.e. building democratic and civilized state. The author discloses peculiarities of ethnos national values development using specific sources. It is underlined that renewal and modernization of Kazakhstan society represents new stage in the national value development, and its typical feature is integration process based on peoples- friendship, cultural principles of interethnic communication.
Abstract: In this study, we are interested in the economic lot
scheduling problem (ELSP) that considers manufacturing of the
serviceable products and remanufacturing of the reworked products. In
this paper, we formulate a mathematical model for the ELSP with
reworks using the basic period approach. In order to solve this
problem, we propose a search algorithm to find the cyclic multiplier ki
of each product that can be cyclically produced for every ki basic
periods. This research also uses two heuristics to search for the optimal
production sequence of all lots and the optimal time length of the basic
period so as to minimize the average total cost. This research uses a
numerical example to show the effectiveness of our approach.
Abstract: LSP routing is among the prominent issues in MPLS
networks traffic engineering. The objective of this routing is to
increase number of the accepted requests while guaranteeing the
quality of service (QoS). Requested bandwidth is the most important
QoS criterion that is considered in literatures, and a various number
of heuristic algorithms have been presented with that regards. Many
of these algorithms prevent flows through bottlenecks of the network
in order to perform load balancing, which impedes optimum
operation of the network. Here, a modern routing algorithm is
proposed as MIRAD: having a little information of the network
topology, links residual bandwidth, and any knowledge of the
prospective requests it provides every request with a maximum
bandwidth as well as minimum end-to-end delay via uniform load
distribution across the network. Simulation results of the proposed
algorithm show a better efficiency in comparison with similar
algorithms.
Abstract: In this paper the problem of face recognition under variable illumination conditions is considered. Most of the works in the literature exhibit good performance under strictly controlled acquisition conditions, but the performance drastically drop when changes in pose and illumination occur, so that recently number of approaches have been proposed to deal with such variability. The aim of this work is to introduce an efficient local appearance feature extraction method based steerable pyramid (SP) for face recognition. Local information is extracted from SP sub-bands using LBP(Local binary Pattern). The underlying statistics allow us to reduce the required amount of data to be stored. The experiments carried out on different face databases confirm the effectiveness of the proposed approach.
Abstract: Swarm principles are increasingly being used to design controllers for the coordination of multi-robot systems or, in general, multi-agent systems. This paper proposes a two-dimensional Lagrangian swarm model that enables the planar agents, modeled as point masses, to swarm whilst effectively avoiding each other and obstacles in the environment. A novel method, based on an extended Lyapunov approach, is used to construct the model. Importantly, the Lyapunov method ensures a form of practical stability that guarantees an emergent behavior, namely, a cohesive and wellspaced swarm with a constant arrangement of individuals about the swarm centroid. Computer simulations illustrate this basic feature of collective behavior. As an application, we show how multiple planar mobile unicycle-like robots swarm to eventually form patterns in which their velocities and orientations stabilize.
Abstract: Logistics is part of the supply chain processes that
plans, implements, and controls the efficient and effective forward
and reverse flow and storage of goods, services, and related
information between the point of origin and the point of consumption
in order to meet customer requirements. This research aims to
investigate the current status and future direction of the use of
Information Technology (IT) for logistics, focusing on Supply Chain
Management (SCM) and E-Commerce adoption in Malaysia.
Therefore, this research stresses on the type of technology being
adopted, factors, benefits and barriers affecting the innovation in
SCM and E-Commerce technology adoption among Logistics
Service Providers (LSP). A mailed questionnaire survey was
conducted to collect data from 265 logistics companies in Johor. The
research revealed a high level of SCM technology adoption among
LSP as they had adopted SCM technology in various business
processes while they perceived a high level of benefits from SCM
adoption.
Abstract: The steam cracking reactions are always accompanied with the formation of coke which deposits on the walls of the tubular reactors. The investigation has attempted to control catalytic coking by the applying aluminum, zinc and ceramic coating like aluminum-magnesium by thermal spray and pack cementation method. Rate of coke formation during steam cracking of naphtha has been investigated both for uncoated stainless steel (with different alloys) and metal coating constructed with thermal Spray and pack cementation method with metal powders of Aluminum, Aluminum-Magnesium, zinc, silicon, nickel and chromium. The results of the study show that passivating the surface of SS321 with a coating of Aluminum and Aluminum-Magnesium can significantly reduce the rate of coke deposition during naphtha pyrolysis. SEM and EDAX techniques (Philips XL Series) were used to examine the coke deposits formed by the metal-hydrocarbon reactions. Our objective was to separate the different stages by identifying the characteristic morphologies.
Abstract: The paper reviews the relationship between spatial
and transportation planning in the Southern African Development
Community (SADC) region of Sub-Saharan Africa. It argues that
most urbanisation in the region has largely occurred subsequent to
the 1950s and, accordingly, urban development has been
profoundly and negatively affected by the (misguided) spatial and
institutional tenets of modernism. It demonstrates how a
considerable amount of the poor performance of these settlements
can be directly attributed to this. Two factors in particular about the
planning systems are emphasized: the way in which programmatic
land-use planning lies at the heart of both spatial and transportation
planning; and the way on which transportation and spatial planning
have been separated into independent processes. In the final
section, the paper identifies ways of improving the planning
system. Firstly, it identifies the performance qualities which
Southern African settlements should be seeking to achieve.
Secondly, it focuses on two necessary arenas of change: the need to
replace programmatic land-use planning practices with structuralspatial
approaches; and it makes a case for making urban corridors
a spatial focus of integrated planning, as a way of beginning the
restructuring and intensification of settlements which are currently
characterised by sprawl, fragmentation and separation
Abstract: In this paper, we first give the representation of the general solution of the following least-squares problem (LSP): Given matrices X ∈ Rn×p, B ∈ Rp×p and A0 ∈ Rr×r, find a matrix A ∈ Rn×n such that XT AX − B = min, s. t. A([1, r]) = A0, where A([1, r]) is the r×r leading principal submatrix of the matrix A. We then consider a best approximation problem: given an n × n matrix A˜ with A˜([1, r]) = A0, find Aˆ ∈ SE such that A˜ − Aˆ = minA∈SE A˜ − A, where SE is the solution set of LSP. We show that the best approximation solution Aˆ is unique and derive an explicit formula for it. Keyw