Abstract: Glutathione S-transferase was purified from human
erythrocytes and effects of some polyphenols were investigated on
the enzyme activity. The purification procedure was performed on
Glutathione-Agarose affinity chromatography after preparation of
erythrocytes hemolysate with a yield of 81%. The purified enzyme
showed a single band on the SDS-PAGE. The effects of some
poliphenolic compounds such as catechin, dopa, dopamine, progallol
and catechol were examined on the in vitro GST activity. Catechin
was determined to be inhibitor for the enzyme, but others were not
effective on the enzyme as inhibitors or activators. IC50 value -the
concentration of inhibitor which reduces enzyme activity by 50%-
was estimated to be 10 mM. Ki constants were also calculated as 6.38
± 0,70 mM with GSH substrate, and 3.86 ± 0,78 mM with CDNB
substrate using the equations of graphs for the inhibitor, and its
inhibition type was determined as non-competitive.
Abstract: A precision CMOS chopping amplifier is adopted in this work to improve a CMOS temperature sensor high sensitive enough for intracranial temperature monitoring. An amplified temperature sensitivity of 18.8 ± 3*0.2 mV/oC is attained over the temperature range from 20 oC to 80 oC from a given 10 samples of the same wafer. The analog frontend design outputs the temperature dependent and the temperature independent signals which can be directly interfaced to a 10 bit ADC to accomplish an accurate temperature instrumentation system.
Abstract: We fabricated the inverted-staggered etch stopper
structure oxide-based TFT and investigated the characteristics of oxide
TFT under the 400 nm wavelength light illumination. When 400 nm
light was illuminated, the threshold voltage (Vth) decreased and
subthreshold slope (SS) increased at forward sweep, while Vth and SS
were not altered when larger wavelength lights, such as 650 nm, 550
nm and 450 nm, were illuminated. At reverse sweep, the transfer curve
barely changed even under 400 nm light. Our experimental results
support that photo-induced hole carriers are captured by donor-like
interface trap and it caused the decrease of Vth and increase of SS. We
investigated the interface trap density increases proportionally to the
photo-induced hole concentration at active layer.
Abstract: Changing in consumers lifestyles and food
consumption patterns provide a great opportunity in developing the
functional food sector in Malaysia. There is only a little knowledge
about whether Malaysian consumers are aware of functional food and
if so what image consumers have of this product. The objective of
this research is to determine the extent to which selected socioeconomic
characteristics and attitudes influence consumers-
awareness of functional food. A survey was conducted in the Klang
Valley, Malaysia where 439 respondents were interviewed using a
structured questionnaire. The result shows that most respondents
have a positive attitude towards functional food. For the binary
logistic estimation, the results indicate that age, income and other
factors such as concern about food safety, subscribing to cooking or
health magazines, being a vegetarian and consumers who have been
involved in a food production company significantly influence
Malaysian consumers- awareness towards functional food.
Abstract: The classification of the protein structure is commonly
not performed for the whole protein but for structural domains, i.e.,
compact functional units preserved during evolution. Hence, a first
step to a protein structure classification is the separation of the
protein into its domains. We approach the problem of protein domain
identification by proposing a novel graph theoretical algorithm. We
represent the protein structure as an undirected, unweighted and
unlabeled graph which nodes correspond the secondary structure
elements of the protein. This graph is call the protein graph. The
domains are then identified as partitions of the graph corresponding
to vertices sets obtained by the maximization of an objective function,
which mutually maximizes the cycle distributions found in the
partitions of the graph. Our algorithm does not utilize any other kind
of information besides the cycle-distribution to find the partitions. If
a partition is found, the algorithm is iteratively applied to each of
the resulting subgraphs. As stop criterion, we calculate numerically
a significance level which indicates the stability of the predicted
partition against a random rewiring of the protein graph. Hence,
our algorithm terminates automatically its iterative application. We
present results for one and two domain proteins and compare our
results with the manually assigned domains by the SCOP database
and differences are discussed.
Abstract: The source voltage of high-power fuel cell shows strong load dependence at comparatively low voltage levels. In order to provide the voltage of 750V on the DC-link for feeding electrical energy into the mains via a three phase inverter a step-up converter with a large step-up ratio is required. The output voltage of this DC/DC-converter must be stabile during variations of the load current and the voltage of the fuel cell. This paper presents the methods and results of the calculation of the efficiency and the expense for the realization for the circuits of the DC/DC-converter that meet these requirements.
Abstract: In this work, the condensation fraction and transition
temperature of neutral many bosonic system are studied within the
static fluctuation approximation (SFA). The effect of the potential
parameters such as the strength and range on the condensate fraction
was investigated. A model potential consisting of a repulsive step
potential and an attractive potential well was used. As the potential
strength or the core radius of the repulsive part increases, the
condensation fraction is found to be decreased at the same
temperature. Also, as the potential depth or the range of the attractive
part increases, the condensation fraction is found to be increased. The
transition temperature is decreased as the potential strength or the
core radius of the repulsive part increases, and it increases as the
potential depth or the range of the attractive part increases.
Abstract: Weblogs are resource of social structure to discover and track the various type of information written by blogger. In this paper, we proposed to use mining weblogs technique for identifying the trends of influenza where blogger had disseminated their opinion for the anomaly disease. In order to identify the trends, web crawler is applied to perform a search and generated a list of visited links based on a set of influenza keywords. This information is used to implement the analytics report system for monitoring and analyzing the pattern and trends of influenza (H1N1). Statistical and graphical analysis reports are generated. Both types of the report have shown satisfactory reports that reflect the awareness of Malaysian on the issue of influenza outbreak through blogs.
Abstract: We consider a cooperative game played by n players against a referee. The players names are randomly distributed among n lockers, with one name per locker. Each player can open up to half the lockers and each player must find his name. Once the game starts the players may not communicate. It has been previously shown that, quite surprisingly, an optimal strategy exists for which the success probability is never worse than 1 − ln 2 ≈ 0.306. In this paper we consider an extension where the number of lockers is greater than the number of players, so that some lockers are empty. We show that the players may still win with positive probability even if there are a constant k number of empty lockers. We show that for each fixed probability p, there is a constant c so that the players can win with probability at least p if they are allowed to open cn lockers.
Abstract: One of the basic concepts in marketing is the concept
of meeting customers- needs. Since customer satisfaction is essential
for lasting survival and development of a business, screening and
observing customer satisfaction and recognizing its underlying
factors must be one of the key activities of every business.
The purpose of this study is to recognize the drivers that effect
customer satisfaction in a business-to-business situation in order to
improve marketing activities. We conducted a survey in which 93
business customers of a manufacturer of Diesel Generator in Iran
participated and they talked about their ideas and satisfaction of
supplier-s services related to its products. We developed the measures
for drivers of satisfaction first by as investigative research (by means
of feedback from executives and customers of sponsoring firm). Then
based on these measures, we created a mail survey, and asked the
respondents to explain their opinion about the sponsoring firm which
was a supplier of diesel generator and similar products. Furthermore,
the survey required the participants to mention their functional areas
and their company features.
In Conclusion we found that there are three drivers for customer
satisfaction, which are reliability, information about product, and
commercial features. Buyers/users from different functional areas
attribute different degree of importance to the last two drivers. For
instance, people from buying and management areas believe that
commercial features are more important than information about
products. But people in engineering, maintenance and production
areas believe that having information about products is more
important than commercial aspects. Marketing experts should
consider the attribute of customers regarding information about the
product and commercial features to improve market share.
Abstract: This study evaluates the performance of horizontal
subsurface flow constructed wetland (HSSF-CW) for the removal of
chlorinated resin and fatty acids (RFAs) from pulp and paper mill
wastewater. The dimensions of the treatment system were 3.5 m x 1.5
m x 0.28 m with surface area of 5.25 m2, filled with fine sand and
gravel. The cell was planted with an ornamental plant species Canna
indica. The removal efficiency of chlorinated RFAs was in the range
of 92-96% at the hydraulic retention time (HRT) of 5.9 days. Plant
biomass and soil (sand and gravel) were analyzed for chlorinated
RFAs content. No chlorinated RFAs were detected in plant biomass
but detected in soil samples. Mass balance studies of chlorinated
RFAs in HSSF-CW were also carried out.
Abstract: Computer modeling has played a unique role in
understanding electrocardiography. Modeling and simulating cardiac
action potential propagation is suitable for studying normal and
pathological cardiac activation. This paper presents a 2-D Cellular
Automata model for simulating action potential propagation in
cardiac tissue. We demonstrate a novel algorithm in order to use
minimum neighbors. This algorithm uses the summation of the
excitability attributes of excited neighboring cells. We try to
eliminate flat edges in the result patterns by inserting probability to
the model. We also preserve the real shape of action potential by
using linear curve fitting of one well known electrophysiological
model.
Abstract: An intuitive user interface for the teleoperation of mobile rescue robots is one key feature for a successful exploration of inaccessible and no-go areas. Therefore, we have developed a novel framework to embed a flexible and modular user interface into a complete 3-D virtual reality simulation system. Our approach is based on a client-server architecture to allow for a collaborative control of the rescue robot together with multiple clients on demand. Further, it is important that the user interface is not restricted to any specific type of mobile robot. Therefore, our flexible approach allows for the operation of different robot types with a consistent concept and user interface. In laboratory tests, we have evaluated the validity and effectiveness of our approach with the help of two different robot platforms and several input devices. As a result, an untrained person can intuitively teleoperate both robots without needing a familiarization time when changing the operating robot.
Abstract: In this paper, a simulated annealing algorithm has been developed to optimize machining parameters in turning operation on cylindrical workpieces. The turning operation usually includes several passes of rough machining and a final pass of finishing. Seven different constraints are considered in a non-linear model where the goal is to achieve minimum total cost. The weighted total cost consists of machining cost, tool cost and tool replacement cost. The computational results clearly show that the proposed optimization procedure has considerably improved total operation cost by optimally determining machining parameters.
Abstract: We present a non standard Euclidean vehicle
routing problem adding a level of clustering, and we revisit the use
of self-organizing maps as a tool which naturally handles such
problems. We present how they can be used as a main operator
into an evolutionary algorithm to address two conflicting
objectives of route length and distance from customers to bus stops
minimization and to deal with capacity constraints. We apply the
approach to a real-life case of combined clustering and vehicle
routing for the transportation of the 780 employees of an
enterprise. Basing upon a geographic information system we
discuss the influence of road infrastructures on the solutions
generated.
Abstract: The intelligent fuzzy input estimator is used to estimate
the input force of the rigid bar structural system in this study. The
fuzzy Kalman filter without the input term and the fuzzy weighting
recursive least square estimator are two main portions of this method.
The practicability and accuracy of the proposed method were verified
with numerical simulations from which the input forces of a rigid bar
structural system were estimated from the output responses. In order to
examine the accuracy of the proposed method, a rigid bar structural
system is subjected to periodic sinusoidal dynamic loading. The
excellent performance of this estimator is demonstrated by comparing
it with the use of difference weighting function and improper the
initial process noise covariance. The estimated results have a good
agreement with the true values in all cases tested.
Abstract: The aim of this contribution is to present a new
approach in modeling the electrical activity of the human heart. A
recurrent artificial neural network is being used in order to exhibit a
subset of the dynamics of the electrical behavior of the human heart.
The proposed model can also be used, when integrated, as a
diagnostic tool of the human heart system.
What makes this approach unique is the fact that every model is
being developed from physiological measurements of an individual.
This kind of approach is very difficult to apply successfully in many
modeling problems, because of the complexity and entropy of the
free variables describing the complex system. Differences between
the modeled variables and the variables of an individual, measured at
specific moments, can be used for diagnostic purposes. The sensor
fusion used in order to optimize the utilization of biomedical sensors
is another point that this paper focuses on. Sensor fusion has been
known for its advantages in applications such as control and
diagnostics of mechanical and chemical processes.
Abstract: Saffron (Crocus sativus) is cultivated as spices,
medicinal and aromatic plant species. At autumn season, heavy
rainfall can cause flooding stress and inhibits growth of saffron. Thus
this research was conducted to study the effect of silver ion (as an
ethylene inhibitor) on growth of saffron under flooding conditions.
The corms of saffron were soaked with one concentration of nano
silver (0, 40, 80 or 120 ppm) and then planting under flooding stress
or non flooding stress conditions. Results showed that number of
roots, root length, root fresh and dry weight, leaves fresh and dry
weight were reduced by 10 day flooding stress. Soaking saffron
corms with 40 or 80 ppm concentration of nano silver rewarded the
effect of flooding stress on the root number, by increasing it.
Furthermore, 40 ppm of nano silver increased root length in stress.
Nano silver 80 ppm in flooding stress, increased leaves dry weight.
Abstract: Proteomics is one of the largest areas of research for
bioinformatics and medical science. An ambitious goal of proteomics
is to elucidate the structure, interactions and functions of all proteins
within cells and organisms. Predicting Protein-Protein Interaction
(PPI) is one of the crucial and decisive problems in current research.
Genomic data offer a great opportunity and at the same time a lot of
challenges for the identification of these interactions. Many methods
have already been proposed in this regard. In case of in-silico
identification, most of the methods require both positive and negative
examples of protein interaction and the perfection of these examples
are very much crucial for the final prediction accuracy. Positive
examples are relatively easy to obtain from well known databases. But
the generation of negative examples is not a trivial task. Current PPI
identification methods generate negative examples based on some
assumptions, which are likely to affect their prediction accuracy.
Hence, if more reliable negative examples are used, the PPI prediction
methods may achieve even more accuracy. Focusing on this issue, a
graph based negative example generation method is proposed, which
is simple and more accurate than the existing approaches. An
interaction graph of the protein sequences is created. The basic
assumption is that the longer the shortest path between two
protein-sequences in the interaction graph, the less is the possibility of
their interaction. A well established PPI detection algorithm is
employed with our negative examples and in most cases it increases
the accuracy more than 10% in comparison with the negative pair
selection method in that paper.
Abstract: Urbanization and regionalization are two different
approaches when it comes to economical structures and development,
infrastructure and mobility, quality of life and living, education,
social cohesion and many other topics. At first glance, the structures
associated with urbanization and regionalization seems to be
contradicting. This paper discusses possibilities of transfer and
cooperation between rural and urban structures. An empirical
investigation contributed to reveal scenarios of supposable forms of
exchange and cooperation of remote rural areas and big cities.