The Comparation of Activation Nuclear Factor Kappa Beta (NFKB) at Rattus Novergicus Strain Wistar Induced by Various Duration High Fat Diet (HFD)

NFκB is a transcription factor regulating many function of the vessel wall. In the normal condition , NFκB is revealed diffuse cytoplasmic expressionsuggesting that the system is inactive. The presence of activation NFκB provide a potential pathway for the rapid transcriptional of a variety of genes encoding cytokines, growth factors, adhesion molecules and procoagulatory factors. It is likely to play an important role in chronic inflamatory disease involved atherosclerosis. There are many stimuli with the potential to active NFκB, including hyperlipidemia. We used 24 mice which was divided in 6 groups. The HFD given by et libitum procedure during 2, 4, and 6 months. The parameters in this study were the amount of NFKB activation ,H2O2 as ROS and VCAM-1 as a product of NFKB activation. H2O2 colorimetryc assay performed directly using Anti Rat H2O2 ELISA Kit. The NFKB and VCAM-1 detection obtained from aorta mice, measured by ELISA kit and imunohistochemistry. There was a significant difference activation of H2O2, NFKB and VCAM-1 level at induce HFD after 2, 4 and 6 months. It suggest that HFD induce ROS formation and increase the activation of NFKB as one of atherosclerosis marker that caused by hyperlipidemia as classical atheroschlerosis risk factor.

Application of Smooth Ergodic Hidden Markov Model in Text to Speech Systems

In developing a text-to-speech system, it is well known that the accuracy of information extracted from a text is crucial to produce high quality synthesized speech. In this paper, a new scheme for converting text into its equivalent phonetic spelling is introduced and developed. This method is applicable to many applications in text to speech converting systems and has many advantages over other methods. The proposed method can also complement the other methods with a purpose of improving their performance. The proposed method is a probabilistic model and is based on Smooth Ergodic Hidden Markov Model. This model can be considered as an extension to HMM. The proposed method is applied to Persian language and its accuracy in converting text to speech phonetics is evaluated using simulations.

Hot Workability of High Strength Low Alloy Steels

The hot deformation behavior of high strength low alloy (HSLA) steels with different chemical compositions under hot working conditions in the temperature range of 900 to 1100℃ and strain rate range from 0.1 to 10 s-1 has been studied by performing a series of hot compression tests. The dynamic materials model has been employed for developing the processing maps, which show variation of the efficiency of power dissipation with temperature and strain rate. Also the Kumar-s model has been used for developing the instability map, which shows variation of the instability for plastic deformation with temperature and strain rate. The efficiency of power dissipation increased with decreasing strain rate and increasing temperature in the steel with higher Cr and Ti content. High efficiency of power dissipation over 20 % was obtained at a finite strain level of 0.1 under the conditions of strain rate lower than 1 s-1 and temperature higher than 1050 ℃ . Plastic instability was expected in the regime of temperatures lower than 1000 ℃ and strain rate lower than 0.3 s-1. Steel with lower Cr and Ti contents showed high efficiency of power dissipation at higher strain rate and lower temperature conditions.

Achieving Fair Share Objectives via Goal-Oriented Parallel Computer Job Scheduling Policies

Fair share is one of the scheduling objectives supported on many production systems. However, fair share has been shown to cause performance problems for some users, especially the users with difficult jobs. This work is focusing on extending goaloriented parallel computer job scheduling policies to cover the fair share objective. Goal-oriented parallel computer job scheduling policies have been shown to achieve good scheduling performances when conflicting objectives are required. Goal-oriented policies achieve such good performance by using anytime combinatorial search techniques to find a good compromised schedule within a time limit. The experimental results show that the proposed goal-oriented parallel computer job scheduling policy (namely Tradeofffs( Tw:avgX)) achieves good scheduling performances and also provides good fair share performance.

Application of Neural Networks for 24-Hour-Ahead Load Forecasting

One of the most important requirements for the operation and planning activities of an electrical utility is the prediction of load for the next hour to several days out, known as short term load forecasting. This paper presents the development of an artificial neural network based short-term load forecasting model. The model can forecast daily load profiles with a load time of one day for next 24 hours. In this method can divide days of year with using average temperature. Groups make according linearity rate of curve. Ultimate forecast for each group obtain with considering weekday and weekend. This paper investigates effects of temperature and humidity on consuming curve. For forecasting load curve of holidays at first forecast pick and valley and then the neural network forecast is re-shaped with the new data. The ANN-based load models are trained using hourly historical. Load data and daily historical max/min temperature and humidity data. The results of testing the system on data from Yazd utility are reported.

A Novel Method Based on Monte Carlo for Simulation of Variable Resolution X-ray CT Scanner: Measurement of System Presampling MTF

The purpose of this work is measurement of the system presampling MTF of a variable resolution x-ray (VRX) CT scanner. In this paper, we used the parameters of an actual VRX CT scanner for simulation and study of effect of different focal spot sizes on system presampling MTF by Monte Carlo method (GATE simulation software). Focal spot size of 0.6 mm limited the spatial resolution of the system to 5.5 cy/mm at incident angles of below 17º for cell#1. By focal spot size of 0.3 mm the spatial resolution increased up to 11 cy/mm and the limiting effect of focal spot size appeared at incident angles of below 9º. The focal spot size of 0.3 mm could improve the spatial resolution to some extent but because of magnification non-uniformity, there is a 10 cy/mm difference between spatial resolution of cell#1 and cell#256. The focal spot size of 0.1 mm acted as an ideal point source for this system. The spatial resolution increased to more than 35 cy/mm and at all incident angles the spatial resolution was a function of incident angle. By the way focal spot size of 0.1 mm minimized the effect of magnification nonuniformity.

Polymerisation Shrinkage of Light−Cured Hydroxyapatite (HA)−Reinforced Dental Composites

The dental composites are preferably used as filling materials due to their esthetic appearances. Nevertheless one of the major problems, during the application of the dental composites, is shape change named as “polymerisation shrinkage" affecting clinical success of the dental restoration while photo-polymerisation. Polymerisation shrinkage of composites arises basically from the formation of a polymer due to the monomer transformation which composes of an organic matrix phase. It was sought, throughout this study, to detect and evaluate the structural polymerisation shrinkage of prepared dental composites in order to optimize the effects of various fillers included in hydroxyapatite (HA)-reinforced dental composites and hence to find a means to modify the properties of these dental composites prepared with defined parameters. As a result, the shrinkage values of the experimental dental composites were decreased by increasing the filler content of composites and the composition of different fillers used had effect on the shrinkage of the prepared composite systems.

Neural Network Ensemble-based Solar Power Generation Short-Term Forecasting

This paper presents the applicability of artificial neural networks for 24 hour ahead solar power generation forecasting of a 20 kW photovoltaic system, the developed forecasting is suitable for a reliable Microgrid energy management. In total four neural networks were proposed, namely: multi-layred perceptron, radial basis function, recurrent and a neural network ensemble consisting in ensemble of bagged networks. Forecasting reliability of the proposed neural networks was carried out in terms forecasting error performance basing on statistical and graphical methods. The experimental results showed that all the proposed networks achieved an acceptable forecasting accuracy. In term of comparison the neural network ensemble gives the highest precision forecasting comparing to the conventional networks. In fact, each network of the ensemble over-fits to some extent and leads to a diversity which enhances the noise tolerance and the forecasting generalization performance comparing to the conventional networks.

An Application for Web Mining Systems with Services Oriented Architecture

Although the World Wide Web is considered the largest source of information there exists nowadays, due to its inherent dynamic characteristics, the task of finding useful and qualified information can become a very frustrating experience. This study presents a research on the information mining systems in the Web; and proposes an implementation of these systems by means of components that can be built using the technology of Web services. This implies that they can encompass features offered by a services oriented architecture (SOA) and specific components may be used by other tools, independent of platforms or programming languages. Hence, the main objective of this work is to provide an architecture to Web mining systems, divided into stages, where each step is a component that will incorporate the characteristics of SOA. The separation of these steps was designed based upon the existing literature. Interesting results were obtained and are shown here.

Design Process of the Fixing Pipes in the Guide Pipe Anchor System for Cable-Stayed Bridges

For the efficient and safe use of the cable-stayed bridge, a design based on the detailed local analysis of the cable anchor system is required. Also, a theoretical design process for the anchor system should be prepared and reviewed. Generally, the size of the fixing pipe in the anchor system is decided according to the specifications prepared by cable-manufacturing companies, and accordingly, there is difficulty determining the initial inner diameters of the fixing pipes. As such, there is no choice but to use the products with the existing sizes. In this study, the existing design process of the fixing pipe, is a type of guide pipe anchor in the cable anchor system, is reviewed, a formula determining the thickness of the fixing pipe is proposed, and the convenience and validity of the suggested equation is compared with the results of the existing designs to verify its convenience and validity.

Realization of Design Features for Linear Flow Splitting in NX 6

Within the collaborative research center 666 a new product development approach and the innovative manufacturing method of linear flow splitting are being developed. So far the design process is supported by 3D-CAD models utilizing User Defined Features in standard CAD-Systems. This paper now presents new functions for generating 3D-models of integral sheet metal products with bifurcations using Siemens PLM NX 6. The emphasis is placed on design and semi-automated insertion of User Defined Features. Therefore User Defined Features for both, linear flow splitting and its derivative linear bend splitting, were developed. In order to facilitate the modeling process, an application was developed that guides through the insertion process. Its usability and dialog layout adapt known standard features. The work presented here has significant implications on the quality, accurateness and efficiency of the product generation process of sheet metal products with higher order bifurcations.

Wireless Building Monitoring and Control System

The building sector is the largest energy consumer and CO2 emitter in the European Union (EU) and therefore the active reduction of energy consumption and elimination of energy wastage are among the main goals in it. Healthy housing and energy efficiency are affected by many factors which set challenges to monitoring, control and research of indoor air quality (IAQ) and energy consumption, especially in old buildings. These challenges include measurement and equipment costs, for example. Additionally, the measurement results are difficult to interpret and their usage in the ventilation control is also limited when taking into account the energy efficiency of housing at the same time. The main goal of this study is to develop a cost-effective building monitoring and control system especially for old buildings. The starting point or keyword of the development process is a wireless system; otherwise the installation costs become too high. As the main result, this paper describes an idea of a wireless building monitoring and control system. The first prototype of the system has been installed in 10 residential buildings and in 10 school buildings located in the City of Kuopio, Finland.

Nonlinear Dynamic Modeling and Active Vibration Control of a System with Fuel Sloshing

Attitude control of aerospace system with liquid containers may face to a problem associate with fuel sloshing. The sloshing phenomena can degrade the stability of control system and in the worst case, interaction between the attitude control system and fuel vibration leading to resonance. In this paper, a full process of nonlinear dynamic modeling of an aerospace launch vehicle with fuel sloshing is given. Then, a new control system based on model reference adaptive filter is proposed and its algorithm is extracted. This controller implemented on the main attitude control system. Finally, numerical simulation of nonlinear model and control system is carried out to examine the performance of the new controller. Results of simulations show that the inconvenient effects of the fuel sloshing by augmenting this control system are reduced and attitude control system performs, satisfactorily.

Optimization of the Process of Osmo – Convective Drying of Edible Button Mushrooms using Response Surface Methodology (RSM)

Simultaneous effects of temperature, immersion time, salt concentration, sucrose concentration, pressure and convective dryer temperature on the combined osmotic dehydration - convective drying of edible button mushrooms were investigated. Experiments were designed according to Central Composite Design with six factors each at five different levels. Response Surface Methodology (RSM) was used to determine the optimum processing conditions that yield maximum water loss and rehydration ratio and minimum solid gain and shrinkage in osmotic-convective drying of edible button mushrooms. Applying surfaces profiler and contour plots optimum operation conditions were found to be temperature of 39 °C, immersion time of 164 min, salt concentration of 14%, sucrose concentration of 53%, pressure of 600 mbar and drying temperature of 40 °C. At these optimum conditions, water loss, solid gain, rehydration ratio and shrinkage were found to be 63.38 (g/100 g initial sample), 3.17 (g/100 g initial sample), 2.26 and 7.15%, respectively.

Green Synthesis of Butyl Acetate, A Pineapple Flavour via Lipase-Catalyzed Reaction

Nowadays, butyl acetate, a pineapple flavor has been applied widely in food, beverage, cosmetic and pharmaceutical industries. In this study, Butyl acetate, a flavor ester was successfully synthesized via green synthesis of enzymatic reaction route. Commercial immobilized lipase from Rhizomucor miehei (Lipozyme RMIM) was used as biocatalyst in the esterification reaction between acetic acid and butanol. Various reaction parameters such as reaction time (RT), temperature (T) and amount of enzyme (E) were chosen to optimize the reaction synthesis in solvent-free system. The optimum condition to produce butyl acetate was at reaction time (RT), 18 hours; temperature (T), 37°C and amount of enzyme, 25 % (w/w of total substrate). Analysis of yield showed that at optimum condition, >78 % of butyl acetate was produced. The product was confirmed as butyl acetate from FTIR analysis whereby the presence of an ester group was observed at wavenumber of 1742 cm-1.

Decision Support System for Farm Management

The emergence of information technology has resulted in an ever-increasing demand to use computers for the efficient management and dissemination of information. Keeping in view the strong need of farmers to collect important and updated information for interactive, flexible and quick decision-making, a model of Decision Support System for Farm Management is developed. The paper discusses the use of Internet technology for the farmers to take decisions. A model is developed for the farmers to access online interactive and flexible information for their farm management. The workflow of the model is presented highlighting the information transfer between different modules.

Observers Design for Systems Modelled by Bond Graphs with Multivariable Monotone Nonlinearities

A methodology to design a nonlinear observer in a bond graph approach is proposed. The class of nonlinear observer with multivariable nonlinearities is considered. A junction structure of the bond graph observer is proposed. The proposed methodology to an electrical transformer and a DC motor including the nonlinear saturation is applied. Nonlinear observers for the transformer and DC motor based on multivariable circle criterion in the physical domain are proposed. In order to show the saturation effects on the transformer and DC motor, simulation results are obtained. Finally, the paper describes that convergence of the estimates to the true states is achieved.

Feature Extraction of Dorsal Hand Vein Pattern Using a Fast Modified PCA Algorithm Based On Cholesky Decomposition and Lanczos Technique

Dorsal hand vein pattern is an emerging biometric which is attracting the attention of researchers, of late. Research is being carried out on existing techniques in the hope of improving them or finding more efficient ones. In this work, Principle Component Analysis (PCA) , which is a successful method, originally applied on face biometric is being modified using Cholesky decomposition and Lanczos algorithm to extract the dorsal hand vein features. This modified technique decreases the number of computation and hence decreases the processing time. The eigenveins were successfully computed and projected onto the vein space. The system was tested on a database of 200 images and using a threshold value of 0.9 to obtain the False Acceptance Rate (FAR) and False Rejection Rate (FRR). This modified algorithm is desirable when developing biometric security system since it significantly decreases the matching time.

A Generalized Framework for Working with Multiagent Systems

The present paper discusses the basic concepts and the underlying principles of Multi-Agent Systems (MAS) along with an interdisciplinary exploitation of these principles. It has been found that they have been utilized for lots of research and studies on various systems spanning across diverse engineering and scientific realms showing the need of development of a proper generalized framework. Such framework has been developed for the Multi-Agent Systems and it has been generalized keeping in mind the diverse areas where they find application. All the related aspects have been categorized and a general definition has been given where ever possible.

Power Optimization Techniques in FPGA Devices: A Combination of System- and Low-Levels

This paper presents preliminary results regarding system-level power awareness for FPGA implementations in wireless sensor networks. Re-configurability of field programmable gate arrays (FPGA) allows for significant flexibility in its applications to embedded systems. However, high power consumption in FPGA becomes a significant factor in design considerations. We present several ideas and their experimental verifications on how to optimize power consumption at high level of designing process while maintaining the same energy per operation (low-level methods can be used additionally). This paper demonstrates that it is possible to estimate feasible power consumption savings even at the high level of designing process. It is envisaged that our results can be also applied to other embedded systems applications, not limited to FPGA-based.