Abstract: Mycophenolic acid “MPA" is a secondary metabolite
of Penicillium bervicompactum with antibiotic and
immunosuppressive properties. In this study, fermentation process
was established for production of mycophenolic acid by Penicillium
bervicompactum MUCL 19011 in shake flask. The maximum MPA
production, product yield and productivity were 1.379 g/L, 18.6 mg/g
glucose and 4.9 mg/L.h respectively. Glucose consumption, biomass
and MPA production profiles were investigated during fermentation
time. It was found that MPA production starts approximately after
180 hours and reaches to a maximum at 280 h. In the next step, the
effects of methionine and acetate concentrations on MPA production
were evaluated. Maximum MPA production, product yield and
productivity (1.763 g/L, 23.8 mg/g glucose and 6.30 mg/L. h
respectively) were obtained with using 2.5 g/L methionine in culture
medium. Further addition of methionine had not more positive effect
on MPA production. Finally, results showed that the addition of
acetate to the culture medium had not any observable effect on MPA
production
Abstract: The main aim of this research is to study the possible
use of recycled fine aggregate made from waste rubble wall to
substitute partially for the natural sand used in the production of
cement and sand bricks. The bricks specimens were prepared by
using 100% natural sand; they were then replaced by recycled fine
aggregate at 25, 50, 75, and 100% by weight of natural sand. A series
of tests was carried out to study the effect of using recycled aggregate
on the physical and mechanical properties of bricks, such as density,
drying shrinkage, water absorption characteristic, compressive and
flexural strength. Test results indicate that it is possible to
manufacture bricks containing recycled fine aggregate with good
characteristics that are similar in physical and mechanical properties
to those of bricks with natural aggregate, provided that the percentage
of recycled fine aggregates is limited up to 50-75%.
Abstract: Basic objective of this study is to create a regression
analysis method that can estimate the length of a plastic hinge which
is an important design parameter, by making use of the outcomes of
(lateral load-lateral displacement hysteretic curves) the experimental
studies conducted for the reinforced square concrete columns. For
this aim, 170 different square reinforced concrete column tests results
have been collected from the existing literature. The parameters
which are thought affecting the plastic hinge length such as crosssection
properties, features of material used, axial loading level,
confinement of the column, longitudinal reinforcement bars in the
columns etc. have been obtained from these 170 different square
reinforced concrete column tests. In the study, when determining the
length of plastic hinge, using the experimental test results, a
regression analysis have been separately tested and compared with
each other. In addition, the outcome of mentioned methods on
determination of plastic hinge length of the reinforced concrete
columns has been compared to other methods available in the
literature.
Abstract: In this paper, we propose an algorithm to compute
initial cluster centers for K-means clustering. Data in a cell is
partitioned using a cutting plane that divides cell in two smaller cells.
The plane is perpendicular to the data axis with the highest variance
and is designed to reduce the sum squared errors of the two cells as
much as possible, while at the same time keep the two cells far apart
as possible. Cells are partitioned one at a time until the number of
cells equals to the predefined number of clusters, K. The centers of
the K cells become the initial cluster centers for K-means. The
experimental results suggest that the proposed algorithm is effective,
converge to better clustering results than those of the random
initialization method. The research also indicated the proposed
algorithm would greatly improve the likelihood of every cluster
containing some data in it.
Abstract: Using neural network we try to model the unknown function f for given input-output data pairs. The connection strength of each neuron is updated through learning. Repeated simulations of crisp neural network produce different values of weight factors that are directly affected by the change of different parameters. We propose the idea that for each neuron in the network, we can obtain quasi-fuzzy weight sets (QFWS) using repeated simulation of the crisp neural network. Such type of fuzzy weight functions may be applied where we have multivariate crisp input that needs to be adjusted after iterative learning, like claim amount distribution analysis. As real data is subjected to noise and uncertainty, therefore, QFWS may be helpful in the simplification of such complex problems. Secondly, these QFWS provide good initial solution for training of fuzzy neural networks with reduced computational complexity.
Abstract: With the advance in wireless networking, IEEE 802.16 WiMAX technology has been widely deployed for several applications such as “last mile" broadband service, cellular backhaul, and high-speed enterprise connectivity. As a result, military employed WiMAX as a high-speed wireless connection for data-link because of its point to multi-point and non-line-of-sight (NLOS) capability for many years. However, the risk of using WiMAX is a critical factor in some sensitive area of military applications especially in ammunition manufacturing such as solid propellant rocket production. The US DoD policy states that the following certification requirements are met for WiMAX: electromagnetic effects on the environment (E3) and Hazards of Electromagnetic Radiation to Ordnance (HERO). This paper discuses the Recommended Power Densities and Safe Separation Distance (SSD) for HERO on WiMAX systems deployed on solid propellant rocket production. The result of this research found that WiMAX is safe to operate at close proximity distances to the rocket production based on AF Guidance Memorandum immediately changing AFMAN 91-201.
Abstract: The inphase/quadrature (I/Q) amplitude and phase
imbalance effects are studied in coherent optical orthogonal
frequency division multiplexing (CO-OFDM) systems. An analytical
model for the I/Q imbalance is developed and supported by
simulation results. The results indicate that the I/Q imbalance degrades the BER performance considerably.
Abstract: Results are presented from a combined experimental
and modeling study undertaken to understand the effect of fuel spray
angle on soot production in turbulent liquid spray flames. The
experimental work was conducted in a cylindrical laboratory furnace
at fuel spray cone angle of 30º, 45º and 60º. Soot concentrations
inside the combustor are measured by filter paper technique. The soot
concentration is modeled by using the soot particle number density
and the mass density based acetylene concentrations. Soot oxidation
occurred by both hydroxide radicals and oxygen molecules. The
comparison of calculated results against experimental measurements
shows good agreement. Both the numerical and experimental results
show that the peak value of soot and its location in the furnace
depend on fuel spray cone angle. An increase in spray angle enhances
the evaporating rate and peak temperature near the nozzle. Although
peak soot concentration increase with enhance of fuel spray angle but
soot emission from the furnace decreases.
Abstract: With the development of the Internet, E-commerce is
growing at an exponential rate, and lots of online stores are built up to
sell their goods online. A major factor influencing the successful
adoption of E-commerce is consumer-s trust. For new or unknown
Internet business, consumers- lack of trust has been cited as a major
barrier to its proliferation. As web sites provide key interface for
consumer use of E-Commerce, we investigate the design of web site to
build trust in E-Commerce from a design science approach. A
conceptual model is proposed in this paper to describe the ontology of
online transaction and human-computer interaction. Based on this
conceptual model, we provide a personalized webpage design
approach using Bayesian networks learning method. Experimental
evaluation are designed to show the effectiveness of web
personalization in improving consumer-s trust in new or unknown
online store.
Abstract: Lycopene, which can be extracted from plants and is
very popular for fruit intake, is restricted for healthy food development
due to its high price. On the other hand, it will get great safety
concerns, especially in the food or cosmetic application, if the raw
material of lycopene is produced by chemical synthesis. In this
project, we provide a key technology to bridge the limitation as
mentioned above. Based on the abundant bioresources of BCRC
(Bioresource Collection and Research Center, Taiwan), a promising
lycopene output will be anticipated by the introduction of fermentation
technology along with industry-related core energy. Our results
showed that addition of tween 80(0.2%) and span 20 produced higher
amount of lycopene. And piperidine, when was added at 48hr to the
cultivation medium, could promote lycopene excretion effectively
also.
Abstract: This investigation examines the effect of the sintering
temperature curve in manufactured nickel powder capillary structure
(wick) for a loop heat pipe (LHP). The sintering temperature curve is
composed of a region of increasing temperature; a region of constant
temperature and a region of declining temperature. The most important
region is that in which the temperature increases, as an index in the
stage in which the temperature increases. The wick of nickel powder is
manufactured in the stage of fixed sintering temperature and the time
between the stage of constant temperature and the stage of falling
temperature. When the slope of the curve in the region of increasing
temperature is unity (equivalent to 10 °C/min), the structure of the
wick is complete and the heat transfer performance is optimal. The
result of experiment test demonstrates that the heat transfer
performance is optimal at 320W; the minimal total thermal resistance
is approximately 0.18°C/W, and the heat flux is 17W/cm2; the internal
parameters of the wick are an effective pore radius of 3.1 μm, a
permeability of 3.25×10-13m2 and a porosity of 71%.
Abstract: This paper unifies power optimization approaches in
various energy converters, such as: thermal, solar, chemical, and
electrochemical engines, in particular fuel cells. Thermodynamics
leads to converter-s efficiency and limiting power. Efficiency
equations serve to solve problems of upgrading and downgrading of
resources. While optimization of steady systems applies the
differential calculus and Lagrange multipliers, dynamic optimization
involves variational calculus and dynamic programming. In reacting
systems chemical affinity constitutes a prevailing component of an
overall efficiency, thus the power is analyzed in terms of an active
part of chemical affinity. The main novelty of the present paper in the
energy yield context consists in showing that the generalized heat
flux Q (involving the traditional heat flux q plus the product of
temperature and the sum products of partial entropies and fluxes of
species) plays in complex cases (solar, chemical and electrochemical)
the same role as the traditional heat q in pure heat engines.
The presented methodology is also applied to power limits in fuel
cells as to systems which are electrochemical flow engines propelled
by chemical reactions. The performance of fuel cells is determined by
magnitudes and directions of participating streams and mechanism of
electric current generation. Voltage lowering below the reversible
voltage is a proper measure of cells imperfection. The voltage losses,
called polarization, include the contributions of three main sources:
activation, ohmic and concentration. Examples show power maxima
in fuel cells and prove the relevance of the extension of the thermal
machine theory to chemical and electrochemical systems. The main
novelty of the present paper in the FC context consists in introducing
an effective or reduced Gibbs free energy change between products p
and reactants s which take into account the decrease of voltage and
power caused by the incomplete conversion of the overall reaction.
Abstract: With today's fast lifestyles and busy schedule, nuclear
families are becoming popular. Thus, the elderly members of these
families are often neglected. This has lead to the popularity of the
concept of Community living for the aged. The elders reside at a
centre, which is controlled by the MANAGER. The manager takes
responsibility of the functioning of the centre which includes taking
care of 'residents' at the centre along with managing the daily chores
of the centre, which he accomplishes with the help of a number of
staff members and volunteers Often the Manager is not an employee
but a volunteer. In such cases especially, time is an important
constraint. A system, which provides an easy and efficient manner of
managing the working of an old age home in detail, will prove to be
of great benefit. We have developed a P.C. based organizer used to
monitor the various activities of an old age home. It is an effective
and easy-to-use system which will enable the manager to keep an
account of all the residents, their accounts, staff members, volunteers,
the centre-s logistic requirements etc. It is thus, a comprehensive
'Organizer' for Old Age Homes.
Abstract: Whereas cellular wireless communication systems are
subject to short-and long-term fading. The effect of wireless channel
has largely been ignored in most of the teletraffic assessment
researches. In this paper, a mathematical teletraffic model is proposed
to estimate blocking and forced termination probabilities of cellular
wireless networks as a result of teletraffic behavior as well as the
outage of the propagation channel. To evaluate the proposed
teletraffic model, gamma inter-arrival and general service time
distributions have been considered based on wireless channel fading
effect. The performance is evaluated and compared with the classical
model. The proposed model is dedicated and investigated in different
operational conditions. These conditions will consider not only the
arrival rate process, but also, the different faded channels models.
Abstract: The effective machine-job assignment of injection
molding machines is very important for industry because it is not
only directly affects the quality of the product but also the
performance and lifetime of the machine as well. The phase of
machine selection was mostly done by professionals or experienced
planners, so the possibility of matching a job with an inappropriate
machine might occur when it was conducted by an inexperienced
person. It could lead to an uneconomical plan and defects. This
research aimed to develop a machine selection system for plastic
injection machines as a tool to help in decision making of the user.
This proposed system could be used both in normal times and in
times of emergency. Fuzzy logic principle is applied to deal with
uncertainty and mechanical factors in the selection of both quantity
and quality criteria. The six criteria were obtained from a plastic
manufacturer's case study to construct a system based on fuzzy logic
theory using MATLAB. The results showed that the system was able
to reduce the defects of Short Shot and Sink Mark to 24.0% and
8.0% and the total defects was reduced around 8.7% per month.
Abstract: In today-s era of plasma and laser cutting, machines using oxy-acetylene flame are also meritorious due to their simplicity and cost effectiveness. The objective to devise a Computer controlled Oxy-Fuel profile cutting machine arose from the increasing demand for metal cutting with respect to edge quality, circularity and lesser formation of redeposit material. The System has an 8 bit micro controller based embedded system, which assures stipulated time response. A new window based Application software was devised which takes a standard CAD file .DXF as input and converts it into numerical data required for the controller. It uses VB6 as a front end whereas MS-ACCESS and AutoCAD as back end. The system is designed around AT89C51RD2, powerful 8 bit, ISP micro controller from Atmel and is optimized to achieve cost effectiveness and also maintains the required accuracy and reliability for complex shapes. The backbone of the system is a cleverly designed mechanical assembly along with the embedded system resulting in an accuracy of about 10 microns while maintaining perfect linearity in the cut. This results in substantial increase in productivity. The observed results also indicate reduced inter laminar spacing of pearlite with an increase in the hardness of the edge region.
Abstract: The hydrolysis kinetics of polycrystalline lithium hydride (LiH) in argon at various low humidities was measured by gravimetry and Raman spectroscopy with ambient water concentration ranging from 200 to 1200 ppm. The results showed that LiH hydrolysis curve revealed a paralinear shape, which was attributed to two different reaction stages that forming different products as explained by the 'Layer Diffusion Control' model. Based on the model, a novel two-stage rate equation for LiH hydrolysis reactions was developed and used to fit the experimental data for determination of Li2O steady thickness Hs and the ultimate hydrolysis rate vs. The fitted data presented a rise of Hs as ambient water concentration cw increased. However, in spite of the negative effect imposed by Hs increasing, the upward trend of vs remained, which implied that water concentration, rather than Li2O thickness, played a predominant role in LiH hydrolysis kinetics. In addition, the proportional relationship between vsHs and cw predicted by rate equation and confirmed by gravimetric data validated the model in such conditions.
Abstract: As days go by, we hear more and more about HIV,
Ebola, Bird Flu and other dreadful viruses which were unknown a
few decades ago. In both detecting and fighting viral diseases
ordinary methods have come across some basic and important
difficulties. Vaccination is by a sense introduction of the virus to the
immune system before the occurrence of the real case infection. It is
very successful against some viruses (e.g. Poliomyelitis), while
totally ineffective against some others (e.g. HIV or Hepatitis-C). On
the other hand, Anti-virus drugs are mostly some tools to control and
not to cure a viral disease. This could be a good motivation to try
alternative treatments. In this study, some key features of possible
physical-based alternative treatments for viral diseases are presented.
Electrification of body parts or fluids (especially blood) with micro
electric signals with adjusted current or frequency is also studied. The
main approach of this study is to find a suitable energy field, with
appropriate parameters that are able to kill or deactivate viruses. This
would be a lengthy, multi-disciplinary research which needs the
contribution of virology, physics, and signal processing experts. It
should be mentioned that all the claims made by alternative cures
researchers must be tested carefully and are not advisable at the time
being.
Abstract: The research study evaluated the performance of
irrigation system by using special scientific tools like Remote
Sensing and GIS technology, so that proper measurements could be
taken for the sustainable agriculture and water management.
Different performance evaluation parameters had been calculated for
the purposed data was gathered from field investigation and different
government and private organizations. According to the calculations,
organic matter ranges from 0.19% (low value) to 0.76% (high value).
In flat irrigation system for wheat yield ranges from 3347.16 to
5260.39 kg/ha, while the total water applied to wheat crop ranges
from 252.94 to 279.19 mm and WUE ranges from 13.07 to 18.37
kg/ha/mm. For rice yield ranges from 3347.47 to 5433.07 kg/ha with
total water supplied to rice crop ranges from 764.71 to 978.15 mm
and WUE ranges from 3.49 to 5.71 kg/ha/mm. Similarly, in raised
bed system wheat yield ranges from 4569.13 to 6008.60 kg/ha, total
water supplied ranges from 158.87 to 185.09 mm and WUE ranges
from 27.20 to 33.54 kg/ha/mm while in rice crop, yield ranges from
5285.04 to 6716.69 kg/ha, total water supplied ranges from 600.72 to
755.06 mm and WUE ranges from 6.41 to 10.05 kg/ha/mm. Almost
51.3% water saving is observed in bed irrigation system as compared
to flat system. Less water supplied to beds is more affective as its
WUE value is higher than flat system where more water is supplied
in both the seasons. Similarly, RWS values show that maximum
water deficit while minimum area is getting adequate water supply.
Greater yield is recorded in bed system as plant per square meter is
more in bed system in comparison of flat system Thus, the integration
of GIS tools to regularly compute performance indices could provide
irrigation managers with the means for managing efficiently the
irrigation system.
Abstract: β-Glucosidase is an important enzyme for production
of ethanol from lignocellulose. With hydrolytic activity on
cellooligosaccharides, especially cellobiose, β-glucosidase removes
product inhibitory effect on cellulases and forms fermentable sugars.
In this study, β-glucosidase encoding gene (BGL1) from traditional
starter yeast Saccharomycosis fibuligera BMQ908 was cloned and
expressed in Pichia pastoris. BGL1 of S. fibuligera BMQ 908 shared
98% nucleotide homology with the closest GenBank sequence
(M22475) but identity in amino-acid sequences of catalytic domains.
Recombinant plasmid pPICZαA/BGL1 containing the sequence
encoding BGL1 mature protein and α-factor secretion signal was
constructed and transformed into methylotrophic yeast P. pastoris by
electroporation. The recombinant strain produced single extracellular
protein with molecular weight of 120 kDa and cellobiase activity of
60 IU/ml. The optimum pH of the recombinant β-glucosidase was 5.0
and the optimum temperature was 50°C.