Iterative Clustering Algorithm for Analyzing Temporal Patterns of Gene Expression

Microarray experiments are information rich; however, extensive data mining is required to identify the patterns that characterize the underlying mechanisms of action. For biologists, a key aim when analyzing microarray data is to group genes based on the temporal patterns of their expression levels. In this paper, we used an iterative clustering method to find temporal patterns of gene expression. We evaluated the performance of this method by applying it to real sporulation data and simulated data. The patterns obtained using the iterative clustering were found to be superior to those obtained using existing clustering algorithms.

Remote Employment: Advantages and Challenges for Egypt-s Labor Force (After the 25thJanuary Revolution)

The growing problem of youth unemployment in Egypt after the 25th January Revolution has directed the attention of some human resource experts towards considering remote employment as a partial remedy for the unemployed youth instead of the unavailable traditional jobs, a trend which will also help with the congested offices and unsolved traffic problem in Cairo and spread a flexible work culture, but despite of that, the main issue remains unresolved for these organizations to deal with the system challenges. In the past few years, in developed countries, there has been a growing trend for many companies to shift to remote employment instead of the traditional office employment for many reasons: due to the growing technological advances that helped some employees do their work from home on a part time basis, the need for achieving an employee-s work balance in the middle of unbalanced complicated life, top management focus on employee-s productivity rather their time spent at work. The objective of this paper is to study and analyze the advantages and challenges that Egypt-s labor force will be facing in their implementation of remote or virtual employment in both government and private organizations after the 25th January revolution. Therefore, the research question will be: What are the advantages and different challenges that Egyptian organizations might face in their implementation for remote employment system and how can they manage these challenges for the system to work effectively? The study is divided into six main parts: the introduction, objective and importance of the study, research problem, methodology, experience of some countries that implemented remote employment, advantages and challenges of implementing remote employment in Egypt and then the conclusion which discuses the results and recommendations of the study.

Improving Multi-storey Building Sensor Network with an External Hub

Monitoring and automatic control of building environment is a crucial application of Wireless Sensor Network (WSN) in which maximizing network lifetime is a key challenge. Previous research into the performance of a network in a building environment has been concerned with radio propagation within a single floor. We investigate the link quality distribution to obtain full coverage of signal strength in a four-storey building environment, experimentally. Our results indicate that the transitional region is of particular concern in wireless sensor network since it accommodates high variance unreliable links. The transitional region in a multi-storey building is mainly due to the presence of reinforced concrete slabs at each storey and the fac┬©ade which obstructs the radio signal and introduces an additional absorption term to the path loss.

Strength Optimization of Induction Hardened Splined Shaft – Material and Geometric Aspects

the current study presents a modeling framework to determine the torsion strength of an induction hardened splined shaft by considering geometry and material aspects with the aim to optimize the static torsion strength by selection of spline geometry and hardness depth. Six different spline geometries and seven different hardness profiles including non-hardened and throughhardened shafts have been considered. The results reveal that the torque that causes initial yielding of the induction hardened splined shaft is strongly dependent on the hardness depth and the geometry of the spline teeth. Guidelines for selection of the appropriate hardness depth and spline geometry are given such that an optimum static torsion strength of the component can be achieved.

A Hybrid Genetic Algorithm for the Sequence Dependent Flow-Shop Scheduling Problem

Flow-shop scheduling problem (FSP) deals with the scheduling of a set of jobs that visit a set of machines in the same order. The FSP is NP-hard, which means that an efficient algorithm for solving the problem to optimality is unavailable. To meet the requirements on time and to minimize the make-span performance of large permutation flow-shop scheduling problems in which there are sequence dependent setup times on each machine, this paper develops one hybrid genetic algorithms (HGA). Proposed HGA apply a modified approach to generate population of initial chromosomes and also use an improved heuristic called the iterated swap procedure to improve initial solutions. Also the author uses three genetic operators to make good new offspring. The results are compared to some recently developed heuristics and computational experimental results show that the proposed HGA performs very competitively with respect to accuracy and efficiency of solution.

Vulnerability Assessment of Blida City

The seismic vulnerability of an urban area is of a great deal for local authorities especially those facing earthquakes. So, it is important to have an efficient tool to assess the vulnerability of existing buildings. The use of the VIP (Vulnerability Index Program) and the GIS (Geographic Information System) let us to identify the most vulnerable districts of an urban area. The use of the vulnerability index method lets us to assess the vulnerability of the center town of Blida (Algeria) which is a historical town and which has grown enormously during the last decades. In this method, three levels of vulnerability are defined. The GIS has been used to build a data base in order to perform different thematic analyses. These analyses show the seismic vulnerability of Blida.

Process Optimization for Enhanced Production of Cell Biomass and Metabolites of Fluorescent Pseudomonad R81

The fluorescent pseudomonad strain R81 is a root colonizing rhizobacteria which promotes the growth of many plants by various mechanisms. Its broth containing siderophore (ironchelating compound) and 2,4- diacetyl phloroglucinol (DAPG) is used for preparing bioinoculant formulations for agronomical applications. Glycerol was found to be the best carbon source for improved biomass production. Splitting of nitrogen source to NH4Cl and urea had a stabilizing effect on pH during batch cultivation. Ltryptophan at 0.5 % in the medium increased the siderophore production to 850 mg/l. During batch cultivation of the strain in a bioreactor, a maximum of 4 g/l of dry cell mass, 1.8 g/l of siderophore and 20 mg/l of DAPG was achieved when glycerol was 15 g/l and C/N ratio was maintained at 12.5. In case of intermittent feeding of fresh medium during fed-batch cultivation, the dry cell mass was increased to 25 g/l with improved production of DAPG to 70 mg/l.

Assessment of Vulnerability and Risk of Taijiang Coastal Areas to Climatic Changes

This study aims to assess the vulnerability and risk of the coastal areas of Taijiang to abnormal oceanographic phenomena. In addition, this study aims to investigate and collect data regarding the disaster losses, land utilization, and other social, economic, and environmental issues in these coastal areas to construct a coastal vulnerability and risk map based on the obtained climate-change risk assessment results. Considering the indexes of the three coastal vulnerability dimensions, namely, man-made facilities, environmental geography, and social economy, this study adopted the equal weighting process and Analytic Hierarchy Process to analyze the vulnerability of these coastal areas to disasters caused by climatic changes. Among the areas with high coastal vulnerability to climatic changes, three towns had the highest coastal vulnerability and four had the highest relative vulnerability. Areas with lower disaster risks were found to be increasingly vulnerable to disasters caused by climatic changes as time progresses.

The Western Resource-Oriented Strategic Perspective Meets the Eastern Tai-Chi Thinking

This study adopts a qualitative approach, which engages in the dialectical discussion on two levels of dyad opposite views. The first level of the dyad opposite views is the Western strategic perspective and the Eastern Tai-Chi thinking. The second level of the dyad opposite views is resource-based view and resource dependence theory. This study concludes the resource-oriented actions for competitive advantage as the metaphor of Tai-Chi consisted of yin and yang. This study argues that the focal firm should adopt bridging strategy during the core competence development period because its core competence development is likely to meet its competitor’s needs of exploring strategy during the competitor’s external resource development stage. In addition, the focal firm should adopt buffering strategy during the external resource development period to prevent its competitor’s the exploiting strategy from attack during the competitor’s core competence development stage. Consequently, this study takes a significant first step toward a novel contextualize understanding of resource development based on strategic perspective and Tai-Chi thinking providing more fully sustainable strategy for competitive advantage.

Modelling and Analysis of a Robust Control of Manufacturing Systems: Flow-Quality Approach

This paper proposes a modeling method of the laws controlling manufacturing systems with temporal and non temporal constraints. A methodology of robust control construction generating the margins of passive and active robustness is being elaborated. Indeed, two paramount models are presented in this paper. The first utilizes the P-time Petri Nets which is used to manage the flow type disturbances. The second, the quality model, exploits the Intervals Constrained Petri Nets (ICPN) tool which allows the system to preserve its quality specificities. The redundancy of the robustness of the elementary parameters between passive and active is also used. The final model built allows the correlation of temporal and non temporal criteria by putting two paramount models in interaction. To do so, a set of definitions and theorems are employed and affirmed by applicator examples.

Investigating Relationship between Product Features and Supply Chain Integration

This paper addresses integration issues in supply chain, and tries to investigate how different aspects of integration are linked with some product features. Integration in this study is interpreted as "internal", "upstream" (supply), and "downstream" (demand). Two features of product innovative and quality are considered. To examine the relationships between supply chain integrations – as mentioned above, and product features, this research follows the survey method in automotive industry.The results imply that supply chain upstream integration has a higher impact on product quality, comparing to internal and supply chain downstream integrations. It is also found that the influence of supply chain downstream integration on product innovation is greater than other variables. In brief, this study mainly tackles the importance of specific level of supply chain integrations and its effects on two product features.

Simulation of Climate Variability for Assessing Impacts on Yield and Genetic Change of Thai Soybean

This study assessed the effects of climate change on Thai soybeans under simulation situations. Our study is focused on temperature variability and effects on growth, yield, and genetic changes in 2 generations of Chiang Mai 60 cultivars. In the experiment, soybeans were exposed to 3 levels of air temperature for 8 h day-1 in an open top chamber for 2 cropping periods. Air temperature levels in each treatment were controlled at 30-33°C (± 2.3) for LT-treatment, 33-36°C ( ± 2.4) for AT-treatment, and 36-40 °C ( ± 3.2) for HT-treatment, respectively. Positive effects of high temperature became obvious at the maturing stage when yield significantly increased in both cropping periods. Results in growth indicated that shoot length at the pre-maturing stage (V3-R3) was more positively affected by high temperature than at the maturing stage. However, the positive effect on growth under high temperature was not found in the 2nd cropping period. Finally, genetic changes were examined in phenotype characteristics by the AFLPs technique. The results showed that the high temperature factor clearly caused genetic change in the soybeans and showed more alteration in the 2nd cropping period.

Determination of a Fair Price for Blood Transportation by Applying the Vehicle Routing Problem: A Case for National Blood Center, Thailand

The National Blood Center, Thai Red Cross Society is responsible for providing blood to hospitals all over the country. When any hospital needs blood, it will have to send the vehicle to pick up at the NBC. There are a lot of vehicles to pick up blood at the NBC every day. Each vehicle is usually empty for inbound trip and a little loaded for outbound. The NBC realized such waste or loss and there have been the third party offered to distribute blood and charge for fee. This paper proposes to apply the vehicle routing problem (VRP) for estimating the fair price. The idea is tested with the real data during seven-day period of 6 – 12 July 2010 to estimate the fair price for transporting blood in Bangkok Metropolitan Region.

A Simplified and Effective Algorithm Used to Mine Similar Processes: An Illustrated Example

The running logs of a process hold valuable information about its executed activity behavior and generated activity logic structure. Theses informative logs can be extracted, analyzed and utilized to improve the efficiencies of the process's execution and conduction. One of the techniques used to accomplish the process improvement is called as process mining. To mine similar processes is such an improvement mission in process mining. Rather than directly mining similar processes using a single comparing coefficient or a complicate fitness function, this paper presents a simplified heuristic process mining algorithm with two similarity comparisons that are able to relatively conform the activity logic sequences (traces) of mining processes with those of a normalized (regularized) one. The relative process conformance is to find which of the mining processes match the required activity sequences and relationships, further for necessary and sufficient applications of the mined processes to process improvements. One similarity presented is defined by the relationships in terms of the number of similar activity sequences existing in different processes; another similarity expresses the degree of the similar (identical) activity sequences among the conforming processes. Since these two similarities are with respect to certain typical behavior (activity sequences) occurred in an entire process, the common problems, such as the inappropriateness of an absolute comparison and the incapability of an intrinsic information elicitation, which are often appeared in other process conforming techniques, can be solved by the relative process comparison presented in this paper. To demonstrate the potentiality of the proposed algorithm, a numerical example is illustrated.

Artificial Accelerated Ageing Test of Silicone Rubber Housing Material for Lightning Arrester

This paper presents the experimental results of silicone rubber housing material for 24kV lightning arrester under artificial accelerated ageing test based on IEC 61109 specifications. Specimens having inclined and alternated shed made of HTV silicone rubber with ATH content and having leakage distance 625 mm were tested continuously 1000 hrs in artificial salt fog chamber. After 1000 hrs of salt fog ageing test, obviously surface erosion was observed on trunk between the upper large shed and the lower small shed near the energized end. Decreasing in hydrophobicity and increasing in hardness were measured on tested specimen comparing with new specimen. Chemical analysis by ATR-FTIR confirmed the observation results.

The Loess Regression Relationship Between Age and BMI for both Sydney World Masters Games Athletes and the Australian National Population

Thousands of masters athletes participate quadrennially in the World Masters Games (WMG), yet this cohort of athletes remains proportionately under-investigated. Due to a growing global obesity pandemic in context of benefits of physical activity across the lifespan, the BMI trends for this unique population was of particular interest. The nexus between health, physical activity and aging is complex and has raised much interest in recent times due to the realization that a multifaceted approach is necessary in order to counteract the obesity pandemic. By investigating age based trends within a population adhering to competitive sport at older ages, further insight might be gleaned to assist in understanding one of many factors influencing this relationship.BMI was derived using data gathered on a total of 6,071 masters athletes (51.9% male, 48.1% female) aged 25 to 91 years ( =51.5, s =±9.7), competing at the Sydney World Masters Games (2009). Using linear and loess regression it was demonstrated that the usual tendency for prevalence of higher BMI increasing with age was reversed in the sample. This trend in reversal was repeated for both male and female only sub-sets of the sample participants, indicating the possibility of improved prevalence of BMI with increasing age for both the sample as a whole and these individual sub-groups.This evidence of improved classification in one index of health (reduced BMI) for masters athletes (when compared to the general population) implies there are either improved levels of this index of health with aging due to adherence to sport or possibly the reduced BMI is advantageous and contributes to this cohort adhering (or being attracted) to masters sport at older ages.

The Establishment of Cause-System of Poor Construction Site Safety and Priority Analysis from Different Perspectives

Construction site safety in China has aroused comprehensive concern all over the world. It is imperative to investigate the main causes of poor construction site safety. This paper divides all the causes into four aspects, namely the factors of workers, object, environment and management and sets up the accident causes element system based on Delphi Method. This is followed by the application of structural equation modeling to examine the importance of each aspect of causes from the standpoints of different roles related to the construction respectively. The results indicate that all the four aspects of factors are in need of improvement, and different roles have different ideas considering the priority of those factors. The paper has instructive significance for the practitioners to take measures to improve construction site safety in China accordingly.

Evaluation of Some Prominent Biomarkers in Rural Type – 2 Diabetes Mellitus Cases in Kanyakumari District, Tamil Nadu, India

Life is beautiful. But, it is decided by genes, environment and the individual and shattered by the natural and / or the invited problems. Most of the global rural helpless masses are struggling for their survival since; they are neglected in all aspects of life including health. Amidst a countless number of miserable diseases in man, diabetes is becoming a dreaded killer and ramifying the entire globe in a jet speed. Diabetes control continues as a Herculean task to the scientific community and the modern society in the 21st century also. T2DM is not pertaining to any age and it can develop even during the childhood. This multifactorial disease abruptly changes the activities of certain vital biomarkers in the present rural T2DM cases. A remarkable variation in the levels of biomarkers like AST, ALT, GGT, ALP, LDH, HbA1C, C- peptide, fasting sugar, post-prandial sugar, sodium, potassium, BUN, creatinine and insulin show the rampant nature of T2DM in this physically active rural agrarian community.

An Enhanced Tool for Implementing Dialogue Forms in Conversational Applications

Natural Language Understanding Systems (NLU) will not be widely deployed unless they are technically mature and cost effective to develop. Cost effective development hinges on the availability of tools and techniques enabling the rapid production of NLU applications through minimal human resources. Further, these tools and techniques should allow quick development of applications in a user friendly way and should be easy to upgrade in order to continuously follow the evolving technologies and standards. This paper presents a visual tool for the structuring and editing of dialog forms, the key element of driving conversation in NLU applications based on IBM technology. The main focus is given on the basic component used to describe Human – Machine interactions of that kind, the Dialogue Manager. In essence, the description of a tool that enables the visual representation of the Dialogue Manager mainly during the implementation phase is illustrated.

Characteristics Analysis of Thermal Resistance of Cryogenic Pipeline in Vacuum Environment

If an unsteady heat transfer or heat impulse happens in part of the cryogenic pipeline system of large space environment simulation equipment while running in vacuum environment, it will lead to abnormal flow of the cryogenic fluid in the pipeline. When the situation gets worse, the cryogenic fluid in the pipeline will have phase change and a gas block which results in the malfunction of the cryogenic pipeline system. Referring to the structural parameter of a typical cryogenic pipeline system and the basic equation, an analytical model and a calculation model for cryogenic pipeline system can be built. The various factors which influence the thermal resistance of a cryogenic pipeline system can be analyzed and calculated by using the qualitative analysis relation deduced for thermal resistance of pipeline. The research conclusion could provide theoretical support for the design and operation of a cryogenic pipeline system