Abstract: This study aimed to determine the possible protective effects of L‐carnitine against gentamicin‐induced nephrotoxicity. Forty male albino rats were divided into 4 groups (10 rats each); Group 1: normal control, group 2: induced nephrotoxicity (gentamicin 50 mg/kg/day S.C; 8 days), group 3: treated with L‐ carnitine (40 mg/kg/d SC for 12 days) and group 4: treated with L‐ carnitine 4 days before and for 8 days in concomitant with gentamicin. Gentamicin‐induced nephrotoxicity (group 2): caused significant increase in serum urea, creatinine, urinary N‐acetyl‐B‐D‐ glucosaminidase (NAG), gamma glutamyl transpeptidase (GGT), urinary total protein and kidney tissue malondialdehyde (MDA) with significant decrease in serum superoxide dismutase (SOD), serum catalase and creatinine clearance and marked tubular necrosis in the proximal convoluted tubules with interruption in the basement membrane around the necrotic tubule compared to the normal control group. L‐carnitine 4 days before and for 8 days in concomitant with gentamicin (group 4) offered marked decrease in serum urea, serum creatinine, urinary NAG, urinary GGT, urinary proteins and kidney tissue MDA, with marked increase in serum SOD, serum catalase and creatinine clearance with marked improvement in the tubular damage compared to gentamicin‐induced nephrotoxicity group. L‐carnitine administered for 12 days produced no change in the parameters mentioned above as compared to the normal control group. In conclusion: L‐carnitine could reduce most of the biochemical parameters and also improve the histopathological features of kidney asscociated with gentamicin induced‐nephrotoxicity.
Abstract: Total Quality Management (TQM) refers to management methods used to enhance quality and productivity in business organizations. Total Quality Management (TQM) has become a frequently used term in discussions concerning quality. Total Quality management has brought rise in demands on the organizations policy and the customers have gained more importance in the organizations focus. TQM is considered as an important management tool, which helps the organizations to satisfy their customers. In present research critical success factors includes management commitment, customer satisfaction, continuous improvement, work culture and environment, supplier quality management, training and development, employee satisfaction and product/process design are studied. A questionnaire is developed to implement these critical success factors in implementation of total quality management in Indian industry. Questionnaires filled by consulting different industrial organizations. Data collected from questionnaires is analyzed by descriptive and importance indexes.
Abstract: Obesity and osteoporosis are the two diseases whose
increasing prevalence and high impact on the global morbidity and
mortality, during the two recent decades, have gained a status of
major health threats worldwide. Obesity purports to affect the bone
metabolism through complex mechanisms. Debated data on the
connection between the bone mineral density and fracture prevalence
in the obese patients are widely presented in literature. There is
evidence that the correlation of weight and fracture risk is sitespecific.
This study is aimed at determining the connection between
the bone mineral density (BMD) and trabecular bone score (TBS)
parameters in Ukrainian women suffering from obesity. We
examined 1025 40-89-year-old women, divided them into the groups
according to their body mass index: Group A included 360 women
with obesity whose BMI was ≥30 kg/m2, and Group B – 665 women
with no obesity and BMI of
Abstract: This paper reviews the model-based qualitative and
quantitative Operations Management research in the context of
Construction Supply Chain Management (CSCM). Construction
industry has been traditionally blamed for low productivity, cost and
time overruns, waste, high fragmentation and adversarial
relationships. The construction industry has been slower than other
industries to employ the Supply Chain Management (SCM) concept
and develop models that support the decision-making and planning.
However the last decade there is a distinct shift from a project-based
to a supply-based approach of construction management. CSCM
comes up as a new promising management tool of construction
operations and improves the performance of construction projects in
terms of cost, time and quality. Modeling the Construction Supply
Chain (CSC) offers the means to reap the benefits of SCM, make
informed decisions and gain competitive advantage. Different
modeling approaches and methodologies have been applied in the
multi-disciplinary and heterogeneous research field of CSCM. The
literature review reveals that a considerable percentage of the CSC
modeling research accommodates conceptual or process models
which present general management frameworks and do not relate to
acknowledged soft Operations Research methods. We particularly
focus on the model-based quantitative research and categorize the
CSCM models depending on their scope, objectives, modeling
approach, solution methods and software used. Although over the last
few years there has been clearly an increase of research papers on
quantitative CSC models, we identify that the relevant literature is
very fragmented with limited applications of simulation,
mathematical programming and simulation-based optimization. Most
applications are project-specific or study only parts of the supply
system. Thus, some complex interdependencies within construction
are neglected and the implementation of the integrated supply chain
management is hindered. We conclude this paper by giving future
research directions and emphasizing the need to develop optimization
models for integrated CSCM. We stress that CSC modeling needs a
multi-dimensional, system-wide and long-term perspective. Finally,
prior applications of SCM to other industries have to be taken into
account in order to model CSCs, but not without translating the
generic concepts to the context of construction industry.
Abstract: By the evolvement in technology, the way of
expressing opinions switched direction to the digital world. The
domain of politics, as one of the hottest topics of opinion mining
research, merged together with the behavior analysis for affiliation
determination in texts, which constitutes the subject of this paper.
This study aims to classify the text in news/blogs either as
Republican or Democrat with the minimum number of features. As
an initial set, 68 features which 64 were constituted by Linguistic
Inquiry and Word Count (LIWC) features were tested against 14
benchmark classification algorithms. In the later experiments, the
dimensions of the feature vector reduced based on the 7 feature
selection algorithms. The results show that the “Decision Tree”,
“Rule Induction” and “M5 Rule” classifiers when used with “SVM”
and “IGR” feature selection algorithms performed the best up to
82.5% accuracy on a given dataset. Further tests on a single feature
and the linguistic based feature sets showed the similar results. The
feature “Function”, as an aggregate feature of the linguistic category,
was found as the most differentiating feature among the 68 features
with the accuracy of 81% in classifying articles either as Republican
or Democrat.
Abstract: A pilot field study was conducted at the Jagjeetpur
Municipal Sewage treatment plant situated in the Haridwar town in
Uttarakhand state, India. The objectives of the present study were to
study the effect of treated wastewater on the production of various
paddy varieties (Sharbati, PR-114, PB-1, Menaka, PB1121 and PB
1509) and the emission of GHG gases (CO2, CH4 and N2O) as
compared to the same varieties grown in the control plots irrigated
with fresh water. Of late, the concept of water footprint assessment
has emerged, which explains enumeration of various types of water
footprints of an agricultural entity from its production to processing
stages. Paddy, the most water demanding staple crop of Uttarakhand
state, displayed a high green water footprint value of 2474.12 m3/
Ton. Most of the wastewater irrigated varieties displayed up to 6%
increase in production, except Menaka and PB-1121, which showed a
reduction in production (6% and 3% respectively), due to pest and
insect infestation. The treated wastewater was observed to be rich in
Nitrogen (55.94 mg/ml Nitrate), Phosphorus (54.24 mg/ml) and
Potassium (9.78 mg/ml), thus rejuvenating the soil quality and not
requiring any external nutritional supplements. A Percentage increase
of GHG gases of irrigation with treated municipal wastewater as
compared to control plots was observed as 0.4% - 8.6% (CH4), 1.1%
- 9.2% (CO2), and 0.07% - 5.8% (N2O). The variety, Sharbati,
displayed maximum production (5.5 ton/ha) and emerged as the most
resistant variety against pests and insects. The emission values of
CH4, CO2 and N2O were 729.31 mg/m2/d, 322.10 mg/m2/d and
400.21 mg/m2/d in water stagnant condition.
This study highlighted a successful possibility of reuse of
wastewater for non-potable purposes offering the potential for
exploiting this resource that can replace or reduce the existing use of
fresh water sources in agriculture sector.
Abstract: As technology-based service industries grow
drastically worldwide; companies are recognizing the importance of
market preoccupancy and have made an effort to capture a large
market to gain the upper hand. To this end, a focus on patents can be
used to determine the properties of a technology, as well as to capture
advantages in technical skills, in comparison with the firm’s
competitors. However, technology-based services largely depend not
only on their technological value but also their economic value, due
to the recognized worth that is passed to a plurality of users. Thus, it
is important to determine whether there are any competitors in the
target areas and what services they provide in any field. Despite this
importance, little effort has been made to systematically benchmark
competitors in order to identify business opportunities. Thus, this
study aims to not only identify each position of technology-centered
service companies in complex market dynamics, but also to discover
new business opportunities. For this, we try to consider both
technology and market environments simultaneously by utilizing
patent data as a representative proxy for technology and trademark
dates as an index for a firm’s target goods and services. Theoretically,
this is one of the earliest attempts to combine patent data and
trademark data to analyze corporate strategies. In practice, the
research results are expected to be used as a decision criterion to
diagnose the economic value that companies can obtain by entering
the market, as well as the technological value to be passed onto their
customers. Thus, the proposed approach can be useful to support
effective technology and business strategies in a firm.
Abstract: Biodiesel as an alternative diesel fuel is steadily gaining more attention and significance. However, there are some drawbacks while using biodiesel regarding its properties that requires it to be blended with petrol based diesel and/or additives to improve the fuel characteristics. This study analyses thermal cracking as an alternative technology to improve biodiesel characteristics in which, FAME based biodiesel produced by transesterification of castor oil is fed into a continuous thermal cracking reactor at temperatures range of 450-500°C and flowrate range of 20-40 g/hr. Experiments designed by response surface methodology and subsequent statistical studies show that temperature and feed flowrate significantly affect the products yield. Response surfaces were used to study the impact of temperature and flowrate on the product properties. After each experiment, the produced crude bio-oil was distilled and diesel cut was separated. As shorter chain molecules are produced through thermal cracking, the distillation curve of the diesel cut fitted more with petrol based diesel curve in comparison to the biodiesel. Moreover, the produced diesel cut properties adequately pose within property ranges defined by the related standard of petrol based diesel. Cold flow properties, high heating value as the main drawbacks of the biodiesel are improved by this technology. Thermal cracking decreases kinematic viscosity, Flash point and cetane number.
Abstract: Based on an indoor environmental quality (IEQ) index established by previous work that indicates the overall IEQ acceptance from the prospect of an occupant in residential buildings in terms of four IEQ factors - thermal comfort, indoor air quality, visual and aural comforts, this study develops a user-friendly IEQ calculator for iOS and Android users to calculate the occupant acceptance and compare the relative performance of IEQ in apartments. “IEQ calculator” is easy to use and it preliminarily illustrates the overall indoor environmental quality on the spot. Users simply input indoor parameters such as temperature, number of people and windows are opened or closed for the mobile application to calculate the scores in four areas: the comforts of temperature, brightness, noise and indoor air quality. The calculator allows the prediction of the best IEQ scenario on a quantitative scale. Any indoor environments under the specific IEQ conditions can be benchmarked against the predicted IEQ acceptance range. This calculator can also suggest how to achieve the best IEQ acceptance among a group of residents.
Abstract: To explore how the brain may recognise objects in its
general,accurate and energy-efficient manner, this paper proposes the
use of a neuromorphic hardware system formed from a Dynamic
Video Sensor (DVS) silicon retina in concert with the SpiNNaker
real-time Spiking Neural Network (SNN) simulator. As a first step
in the exploration on this platform a recognition system for dynamic
hand postures is developed, enabling the study of the methods used
in the visual pathways of the brain. Inspired by the behaviours of
the primary visual cortex, Convolutional Neural Networks (CNNs)
are modelled using both linear perceptrons and spiking Leaky
Integrate-and-Fire (LIF) neurons.
In this study’s largest configuration using these approaches, a
network of 74,210 neurons and 15,216,512 synapses is created and
operated in real-time using 290 SpiNNaker processor cores in parallel
and with 93.0% accuracy. A smaller network using only 1/10th of the
resources is also created, again operating in real-time, and it is able
to recognise the postures with an accuracy of around 86.4% - only
6.6% lower than the much larger system. The recognition rate of the
smaller network developed on this neuromorphic system is sufficient
for a successful hand posture recognition system, and demonstrates
a much improved cost to performance trade-off in its approach.
Abstract: Nowadays, the main goal for modern horticultural
production is an increase the quality. In recent years, the use of
organic fertilizers or biostimulants that can be applied in agriculture
to improve quali-quantitative crop yields has encountered increasing
interest. Biostimulants are gaining importance also for their possible
use in organic and sustainable agriculture, to avoid excessive
fertilizer applications. Consecutive experimental trials were carried
out in the Apulia region (southern Italy) on three herbaceous crops
(cauliflower, pepper, fennel) grown in pots under conventional and
organic fertilization systems without and with biostimulants. The aim
was to determine the effects of three biostimulants (Siapton®10L,
Micotech L, Lysodin Alga-Fert) on quali-quantitative yield
characteristics. At harvest, the quali-quantitative yield characteristics
of each crop were determined. All of the experimental data were
subjected to analysis of variance (ANOVA), and when significant
effects were detected, the means were compared using Tukey’s tests.
These data show large differences in these yield characteristics
between conventional and organic crops, particularly highlighting
higher yields for the conventional crops, while variable results were
generally observed when the biostimulants were applied. In this
context, there were no effects of the biostimulants on the quantitative
yield, whereas there were low positive effects on the qualitative
characteristics, as related to higher dry matter content of cauliflower,
and higher soluble solids content of pepper. Moreover, there were
evident positive effects of the biostimulants with fennel, due to the
lower nitrate content. These latter data are in line with most of the
published literature obtained for other herbaceous crops.
Abstract: This article proposes a new method for application in
communication circuit systems that increase efficiency, PAE, output
power and gain in the circuit. The proposed method is based on a
combination of switching class-E and class-J and has been termed
class-EJ. This method was investigated using both theory and
simulation to confirm ∼72% PAE and output power of >39dBm. The
combination and design of the proposed power amplifier accrues gain
of over 15dB in the 2.9 to 3.5GHz frequency bandwidth. This circuit
was designed using MOSFET and high power transistors. The loadand
source-pull method achieved the best input and output networks
using lumped elements. The proposed technique was investigated for
fundamental and second harmonics having desirable amplitudes for
the output signal.
Abstract: A novel design technique employing CMOS Current
Feedback Operational Amplifier (CFOA) is presented. The feature of
consumption very low power in designing pseudo-OTA is used to
decreasing the total power consumption of the proposed CFOA. This
design approach applies pseudo-OTA as input stage cascaded with
buffer stage. Moreover, the DC input offset voltage and harmonic
distortion (HD) of the proposed CFOA are very low values compared
with the conventional CMOS CFOA due to the symmetrical input
stage. P-Spice simulation results are obtained using 0.18μm MIETEC
CMOS process parameters and supply voltage of ±1.2V, 50μA
biasing current. The p-spice simulation shows excellent improvement
of the proposed CFOA over existing CMOS CFOA. Some of these
performance parameters, for example, are DC gain of 62. dB, openloop
gain bandwidth product of 108 MHz, slew rate (SR+) of
+71.2V/μS, THD of -63dB and DC consumption power (PC) of
2mW.
Abstract: Paranoid ideation is a common thought process that
constitutes a defense against perceived social threats. The current
study aimed at the characterization of paranoid ideation in youths and
to explore the possible predictors involved in the development of
paranoid ideations. Paranoid ideation, shame, submission, early
childhood memories and current depressive, anxious and stress
symptomatology were assessed in a sample of 1516 Portuguese
youths. Higher frequencies of paranoid ideation were observed,
particularly in females and youths from lower socioeconomic status.
The main predictors identified relates to submissive behaviors and
adverse childhood experiences, and especially to shame feelings. The
current study emphasizes that the these predictors are similar to
findings in adults and clinical populations, and future implications to
research and clinical practice aiming at paranoid ideations are
discussed, as well as the pertinence of the study of mediating factors
that allow a wider understanding of this thought process in younger
populations and the prevention of psychopathology in adulthood.
Abstract: The paper presents a novel screening method to
indicate congenital heart diseases (CHD), which otherwise could
remain undetected because of their low level. Therefore, not
belonging to the high-risk population, the pregnancies are not subject
to the regular fetal monitoring with ultrasound echocardiography.
Based on the fact that CHD is a morphological defect of the heart
causing turbulent blood flow, the turbulence appears as a murmur,
which can be detected by fetal phonocardiography (fPCG). The
proposed method applies measurements on the maternal abdomen
and from the recorded sound signal a sophisticated processing
determines the fetal heart murmur. The paper describes the problems
and the additional advantages of the fPCG method including the
possibility of measurements at home and its combination with the
prescribed regular cardiotocographic (CTG) monitoring. The
proposed screening process implemented on a telemedicine system
provides an enhanced safety against hidden cardiac diseases.
Abstract: Toddy sediment (TS) was cultured in a PDA medium
to determine initial yeast load, and also it was undergone sun, shade,
solar, dehumidified cold air (DCA) and hot air oven (at 400, 500 and
60oC) drying with a view to preserve viability of yeast. Thereafter,
this study was conducted according to two factor factorial design in
order to determine best preservation method. Therein the dried TS
from the best drying method was taken and divided into two portions.
One portion was mixed with 3: 7 ratio of TS: rice flour and the
mixture was divided in to two again. While one portion was kept
under in house condition the other was in a refrigerator. Same
procedure was followed to the rest portion of TS too but it was at the
same ratio of corn flour. All treatments were vacuum packed in triple
laminate pouches and the best preservation method was determined
in terms of leavening index (LI). The TS obtained from the best
preservation method was used to make foods (bread and hopper) and
organoleptic properties of it were evaluated against same of ordinary
foods using sensory panel with a five point hedonic scale.
Results revealed that yeast load or fresh TS was 58×106 CFU/g.
The best drying method in preserving viability of yeast was DCA
because LI of this treatment (96%) is higher than that of other three
treatments. Organoleptic properties of foods prepared from best
preservation method are as same as ordinary foods according to Duo
trio test.
Abstract: This paper examines the system protection for cyber-physical
systems (CPS). CPS are particularly characterized by their
networking system components. This means they are able to adapt to
the needs of their users and its environment. With this ability, CPS
have new, specific requirements on the protection against anti-counterfeiting,
know-how loss and manipulation. They increase the
requirements on system protection because piracy attacks can be
more diverse, for example because of an increasing number of
interfaces or through the networking abilities. The new requirements
were identified and in a next step matched with existing protective
measures. Due to the found gap the development of new protection
measures has to be forced to close this gap. Moreover a comparison
of the effectiveness between selected measures was realized and the
first results are presented in this paper.
Abstract: This paper presents the results of an experimental
study undertaken to evaluate the local bond stress-slip response of
short embedment of reinforcing bars in normal concrete (NC) and
high performance fiber reinforced cement composites (HPFRCC)
blocks. Long embedment was investigated as well to gain insights on
the distribution of strain, slip, bar stress and bond stress along the bar
especially in post-yield range. A total of 12 specimens were tested,
by means of pull-out of the reinforcing bars from concrete blocks. It
was found that the enhancement of local bond strength can be
reached up to 50% and ductility of the bond behavior was improved
significantly if HPFRCC is used. Also, under a constant strain at
loaded end, HPFRCC has delayed yielding of bars at other location
from the loaded end. Hence, the reduction of bond stress was slower
for HPFRCC in comparison with NC. Due to the same reason, the
total slips at loaded end for HPFRCC was smaller than NC as
expected. Test results indicated that HPFRCC has better bond slip
behavior which makes it a suitable material to be employed in
anchorage zone such as beam-column joints.
Abstract: The fatigue life of tubular joints commonly found in
offshore industry is not only dependent on the value of hot-spot stress
(HSS), but is also significantly influenced by the through-thethickness
stress distribution characterized by the degree of bending
(DoB). The determination of DoB values in a tubular joint is essential
for improving the accuracy of fatigue life estimation using the stresslife
(S–N) method and particularly for predicting the fatigue crack
growth based on the fracture mechanics (FM) approach. In the
present paper, data extracted from finite element (FE) analyses of
tubular KT-joints, verified against experimental data and parametric
equations, was used to investigate the effects of geometrical
parameters on DoB values at the crown 0°, saddle, and crown 180°
positions along the weld toe of central brace in tubular KT-joints
subjected to axial loading. Parametric study was followed by a set of
nonlinear regression analyses to derive DoB parametric formulas for
the fatigue analysis of KT-joints under axial loads. The tubular KTjoint
is a quite common joint type found in steel offshore structures.
However, despite the crucial role of the DoB in evaluating the fatigue
performance of tubular joints, this paper is the first attempt to study
and formulate the DoB values in KT-joints.
Abstract: Mass media campaigns against obesity are often
designed to impact large audiences. This usually means that their
audience is defined based on general demographic characteristics like
age, gender, occupation etc., not taking into account psychographics
like behavior, motivations, wants, etc. Using psychographics, as the
base for the audience segmentation, is a common practice in case of
successful campaigns, as it allows developing more relevant
messages. It also serves a purpose of identifying key segments, those
that generate the best return on investment. For a health campaign,
that would be segments that have the best chance of being converted
into healthy lifestyle at the lowest cost. This paper presents the
limitations of the demographic targeting, based on the findings from
the reception study of IMSS (Mexican Social Security Institute) antiobesity
TV commercials and proposes mothers as the first level of
segmentation, in the process of identifying the key segment for these
campaigns.