Abstract: Since the emergence of e-Commerce, the world of
business has witnessed a radical shift in the way business activities
are conducted. However, the emergence of m-Commerce has further
pushed the boundaries of virtual commerce revolution. As a result,
there seems to be a growing blur in the distinction between e-
Commerce and m-Commerce. In addition, existing definitions for
both forms of commerce highlight characteristics (e.g. type of device
and activity conducted) that may be applicable to both concepts. The
aim of this paper is to identify the characteristics that help define and
delineate between e- and m- Commerce. The paper concludes that
characteristics of mobility, ubiquity and immediacy provide a clearer
and simpler template to distinguish between e-Commerce and m-
Commerce.
Abstract: Hot aqueous and methanol extracts of the two selected
herbal medicines such are Vellarugu chooranam (V.C) and
Amukkirai Chooranam (A.C) were examined for total phenolic and
flavonoid contents and in vitro antioxidant activity using four
different methods. The total phenolic and flavonoid contents in
methanol extract of V.C were found to be higher (44.41±1.26mg
GAE/g; 174.44±9.32mg QE/g) than in the methanol extract of A.C
(20.56±0.67mg GAE/g; 7.21±0.85mg QE/g). Hot methanol and
aqueous extracts of both medicines showed low antioxidant activity
in DPPH, ABTS, and FRAP methods and Iron chelating activity not
found at highest possible concentration. V.C contains higher
concentrations of total phenolic and flavonoid contents than A.C and
can also exert greater antioxidant activity than A.C, although the
activities demonstrated were lower than the positive control Trolox.
The in vitro antioxidant activity was not related with the total
phenolic and flavonoid contents of the methanol and aqueous extracts
of both herbal medicines (A.C and V.C).
Abstract: Immunomodulators are substances that alter immune
system via dynamic regulation of messenger molecules. It can be
divided into immunostimulant and immunosuppressant. It can help to
increase immunity of people with a low immune system, and also can
help to normalize an overactive immune system. Aim of this study is
to investigate the effects of in vitro exposure to low and high doses of
several immunomodulators which include caffeine, kaloba and
quercetin on antigen-stimulated whole blood culture cytokine
production. Whole blood samples were taken from 5 healthy males
(age: 32 ± 12 years; weight: 75.7 ± 6.1 kg; BMI: 24.3 ± 1.5 kg/m2)
following an overnight fast with no vigorous activity during the
preceding 24 h. The whole blood was then stimulated with 50 μl of
100 x diluted Pediacel vaccine and low or high dose of
immunomodulators in the culture plate. After 20 h incubation (5%
CO2, 37°C), it was analysed using the Evidence Investigator to
determine the production of cytokines including IL-2, IL-4, IL-10,
IFN-γ, and IL-1α. Caffeine and quercetin showed a tendency towards
decrease cytokine production as the doses were increased. On the
other hand, an upward trend was evident with kaloba, where a high
dose of kaloba seemed to increase the cytokine production. In
conclusion, we found that caffeine and quercetin have potential as
immunosuppressant and kaloba as immunostimulant.
Abstract: Persea declinata (Bl.) Kosterm is a member of the
Lauraceae family, widely distributed in Southeast Asia. It is from the
same genus with avocado (Persea americana Mill), which is widely
consumed as food and for medicinal purposes. In the present study,
we examined the anticancer properties of Persea declinata (Bl.)
Kosterm bark methanolic crude extract (PDM). PDM exhibited a
potent antiproliferative effect in MCF-7 human breast cancer cells,
with an IC50 value of 16.68 .g/mL after 48h of treatment. We
observed that PDM caused cell cycle arrest and subsequent apoptosis
in MCF-7 cells, as exhibited by increased population at G0/G1 phase,
higher lactate dehydrogenase (LDH) release, and DNA
fragmentation. Mechanistic studies showed that PDM caused
significant elevation in ROS production, leading to perturbation of
mitochondrial membrane potential, cell permeability, and activation
of caspases-3/7. On the other hand, real-time PCR and Western blot
analysis showed that PDM treatment increased the expression of the
proapoptotic molecule, Bax, but decreased the expression of
prosurvival proteins, Bcl-2 and Bcl-xL, in a dose-dependent manner.
These findings imply that PDM could inhibit proliferation in MCF-7
cells via cell cycle arrest and apoptosis induction, indicating its
potential as a therapeutic agent worthy of further development.
Abstract: Heavy metals are one of the major groups of
contaminants in the environment and many of them are toxic even at
very low concentration in plants and animals. However, some metals
play important roles in the biological function of many enzymes in
living organisms. Metals such as zinc, iron, and cooper are important
for survival and activity of enzymes in plants, however heavy metals
can inhibit enzyme which is responsible for defense system of plants.
Polyphenol oxidase (PPO) is a copper-containing metalloenzyme
which is responsible for enzymatic browning reaction of plants.
Enzymatic browning is a major problem for the handling of
vegetables and fruits in food industry. It can be increased and
effected with many different futures such as metals in the nature and
ground. In the present work, PPO was isolated and characterized
from green leaves of red poppy plant (Papaverr hoeas). Then, the
effect of some known antibrowning agents which can form
complexes with metals and metals were investigated on the red poppy
PPO activity. The results showed that glutathione was the most
potent inhibitory effect on PPO activity. Cu(II) and Fe(II) metals
increased the enzyme activities however, Sn(II) had the maximum
inhibitory effect and Zn(II) and Pb(II) had no significant effect on the
enzyme activity. In order to reduce the effect of heavy metals, the
effects of metal-antibrowning agent complexes on the PPO activity
were determined. EDTA and metal complexes had no significant
effect on the enzyme. L-ascorbic acid and metal complexes decreased
but L-ascorbic acid-Cu(II)-complex had no effect. Glutathione–metal
complexes had the best inhibitory effect on Red poppy leaf PPO
activity.
Abstract: In Capitalism all economic activity rests upon a set of
core institutional foundations, main from which are privately owned
capital assets and profit. How these core institutional foundations are
working in former soviet countries, in particular in Travel and
Tourism Industry of Georgia?
The role of Travel and Tourism as a key pillar of economic growth
is being increasingly recognized by governments in all regions of the
world. For the last few years Georgia succeeded in the World Bank
and IFC “Doing Business” rankings. Despite of that, during decades
totally different statistical data of the tourism sector were provided by
the different State bodies; economic parameters were published few,
or not published at all.
The frequency and extent of property rights violation in Georgia
has repeatedly been the subject of concern for the last decade. Total
value of abrogated by the former Georgian Government private
property is estimated approximately in US$4-5 billion.
Thus, if economic profitability is unknown and property rights are
not protected – that means that the main institutional foundations of
capitalism in Georgia, are not working properly yet, that cause
management problems at all levels of the national Travel and
Tourism industry of Georgia.
Abstract: This paper presents an anthropometric study
conducted to 300 employees in a maquiladora industry that belongs
to the cluster of medical products as part of a research project to
pretend simulate workplace conditions under which operators
conduct their activities. This project is relevant because traditionally
performed a study to design ergonomic workspaces according to
anthropometric profile of users, however, this paper demonstrates the
importance of making decisions when the infrastructure cannot be
adapted for economic whichever put emphasis on user activity.
Abstract: Ficus deltoidea from the Moraceae family is a popular
medicinal herb in Malaysia. It possesses strong antioxidant and antiinflammatory
properties. In the present study, the anti-inflammatory
effects of F. deltoidea extract on UVB-irradiated HaCaT
Keratinocytes were investigated. HaCaT Keratinocytes were UVBirradiated
(12.5 mJ/cm3) and were treated with 0.05, 0.08 or 0.1% of
F. deltoidea extract. Cell viability following UVB irradiation was
significantly higher in the groups treated with the F. deltoidea extract
at doses of 0.05, 0.08 or 0.1% than in control group with UVB
irradiation only. Tumor necrosis factor-α (TNF-α), interleukin-1α
(IL-1α), interleukin-6 (IL-6) and cyclooxygenase (COX-2) play
primary roles in the inflammation process upon UV irradiation and
are known to be stimulated by UVB irradiation. Treatment with the
F. deltoidea extract dramatically inhibited the UV-induced TNF-α,
IL-1α, IL-6, and COX-2 expression. These results suggest that the F.
deltoidea extract inhibits the production of pro-inflammatory
cytokines and may be an effective protective agent for the treatment
of skin diseases.
Abstract: The aim of this paper is to analyze the ability to
identify and acquire knowledge from external sources at the regional
level in the Czech Republic. The results show that the most important
sources of knowledge for innovative activities are sources within the
businesses themselves, followed by customers and suppliers.
Furthermore, the analysis of relationships between the objective of
the innovative activity and the ability to identify and acquire
knowledge implies that knowledge obtained from (1) customers aims
at replacing outdated products and increasing product quality; (2)
suppliers aims at increasing capacity and flexibility of production;
and (3) competing businesses aims at growing market share and
increasing the flexibility of production and services. Regions should
therefore direct their support especially into development and
strengthening of networks within the value chain.
Abstract: The article demonstrates on a case study how it is
possible to identify MSD risk. It is based on a dissertation Risk
identification model of occupational diseases formation in relation to
the work activity that determines what risk can endanger workers who
are exposed to the specific risk factors. It is evaluated based on
statistical calculations. These risk factors are main cause of upperextremities
musculoskeletal disorders.
Abstract: The main objective of this study was to identify
factors and conditions that motivated and encouraged students
towards the math class and the factors that made this class an
attractive and lovely one. To do this end, questionnaires consisting of
15 questions were distributed among 85 math teachers working in
schools of Zahedan. Having collected and reviewed these
questionnaires, it was shown that doing activity in math class
(activity of students while teaching) and previous math teachers'
behaviors have had much impact on encouraging the students
towards mathematics. Separation of educational classroom of
mathematics from the main classroom (which is decorated with crafts
created by students themselves with regard to math book including
article, wall newspaper, figures and formulas), peers, size and
appearance of math book, first grade teachers in each educational
level, among whom the Elementary first grade teachers had more
importance and impact, were among the most influential and
important factors in this regard. Then, school environment, family,
conducting research related to mathematics, its application in daily
life and other courses and studying the history of mathematics were
categorized as important factors that would increase the students’
interest in mathematics.
Abstract: Red River Gum (Eucalyptus camaldulensis) is a tree
of the genus Eucalyptus widely distributed in Algeria and in the
world. The value of its aromatic secondary metabolites offers new
perspectives in the pharmaceutical industry. This strategy can
contribute to the sustainable development of our country. Preliminary
tests performed on the essential oil of Eucalyptus camendulensis
showed that this oil has antibacterial activity vis-à-vis the bacterial
strains (Enterococcus feacalis, Enterobacter cloaceai, Proteus
microsilis, Escherichia coli, Klebsiella pneumonia, and Pseudomonas
aeruginosa) and antifungic (Fusarium sporotrichioide and Fusarium
graminearum). The culture medium used was nutrient broth Muller
Hinton. The interaction between the bacteria and the essential oil is
expressed by a zone of inhibition with diameters of MIC indirectly
expression of. And we used the PDA medium to determine the fungal
activity. The extraction of the aromatic fraction (essentially oilhydrolat)
of the fresh aerian part of the Eucalyptus camendulensis
was performed by hydrodistillation. The average essential oil yield is
0.99%. The antimicrobial and fungal study of the essential oil and
hydrosol showed a high inhibitory effect on the growth of pathogens.
Abstract: The lactic acid bacteria (LAB) were isolated from
10 samples of fermented foods (Sa-tor-dong and Bodo) in South
locality of Thailand. The 23 isolates of lactic acid bacteria were
selected, which were exhibited a clear zone and growth on MRS
agar supplemented with CaCO3. All of lactic acid bacteria were
tested on morphological and biochemical. The result showed that
all isolates were Gram’s positive, non-spore forming but only
10 isolates displayed catalase negative. The 10 isolates including
BD1 .1, BD 1.2, BD 2.1, BD2.2, BD 2.3, BD 3.1, BD 4.1, BD 5.2,
ST 4.1 and ST 5.2 were selected for inhibition activity
determination. Only 2 strains (ST 4.1 and BD 2.3) showed
inhibition zone on agar, when using Escherichia coli sp. as target
strain. The ST 4.1 showed highest inhibition zone on agar, which
was selected for probiotic property testing. The ST4.1 isolate
could grow in MRS broth containing a high concentration of
sodium chloride 6%, bile salts 7%, pH 4-10 and vary temperature
at 15-45°C.
Abstract: Natural antimicrobials are used to preserve foods that
can be found in plants, animals, and microorganisms. Antimicrobial
substances are natural or artificial agents that produced by
microorganisms or obtained semi/total chemical synthesis are used at
low concentrations to inhibit the growth of other microorganisms.
Food borne pathogens and spoilage microorganisms are inactivated
by the use of antagonistic microorganisms and their metabolites.
Yeasts can produce toxic proteins or glycoproteins (toxins) that cause
inhibition of sensitive bacteria and yeast species. Antimicrobial
substance producing phenotypes belonging different yeast genus
were isolated from different sources. Toxins secreted by many yeast
strains inhibiting the growth of other yeast strains. These strains show
antimicrobial activity, inhibiting the growth of mold and bacteria.
The effect of antimicrobial agents produced by yeasts can be
extremely fast, and therefore may be used in various treatment
procedures. Rapid inhibition of microorganisms is possibly caused by
microbial cell membrane lipopolysaccharide binding and in
activation (neutralization) effect. Antimicrobial agents inhibit the
target cells via different mechanisms of action.
Abstract: The objectives of this study are to find out the
approaches to promote healthy recreation activities for elderly
tourists and develop Bang Nam Phueng Floating Market to be a
health tourism attraction. The research methodology was to analyze
internal and external situations according to MP-MF and the MCSTEPS
principles.
As for the results of this study the researcher found that the
healthy recreational activities for elderly tourists could be divided in
7 groups; travelling Bang Nam Phueng Floating Market activity,
homestay relaxation, arts center platform activity, healthy massage
activity, paying homage to a Buddha image activity, herbal joss-stick
home activity, making local desserts and food activity.
Abstract: The construction of a new airport or the extension of
an existing one requires massive investments and many times public
private partnerships were considered in order to make feasible such
projects. One characteristic of these projects is uncertainty with
respect to financial and environmental impacts on the medium to long
term. Another one is the multistage nature of these types of projects.
While many airport development projects have been a success, some
others have turned into a nightmare for their promoters.
This communication puts forward a new approach for airport
investment risk assessment. The approach takes explicitly into
account the degree of uncertainty in activity levels prediction and
proposes milestones for the different stages of the project for
minimizing risk. Uncertainty is represented through fuzzy dual theory
and risk management is performed using dynamic programming. An
illustration of the proposed approach is provided.
Abstract: Azadirachta excelsa or locally known as sentang are
frequently used as a traditional medicine by diabetes patients in
Malaysia. However, less attention has been given to their toxicity
effect. Thus, the study is an attempt to examine the protective effect
of A. excelsa on the pancreas and to determine possible toxicity
mediated by the extract. Diabetes was induced experimentally in rats
by high-fat-diet for 16 weeks followed by intraperitoneal injection of
streptozotocin at dosage of 35 mg/kg of body weight. Declination of
the fasting blood glucose level was observed after continuous
administration of A. excelsa for 14 days twice daily. This is due to the
refining structure of the pancreas. However, surprisingly, the plant
extract reduced the leukocytes, erythrocytes, hemoglobin, MCHC and
lymphocytes. In addition, the rat treated with the plant extract
exhibited increment in AST and eosinocytes level. Overall, the
finding shows that A. excelsa possesses antidiabetic activity by
improving the structure of pancreatic islet of Langerhans but
involved in ameliorating of hematology and biochemical parameters.
Abstract: This paper analyzes innovation trends in South Korea
by means of the number of patent applications filed by residents and
nonresidents during the period 1965 to 2012. Making use of patent
data released by the World Intellectual Property Organization
(WIPO), we search for the presence of multiple structural changes in
patent application series in this country. These changes may suggest
that firms’ innovative activity has been modified as a result of
implementing some science, technology and innovation (STI)
policies. Accordingly, the new regulations implemented in this
country in the last decades have influenced its innovative activity.
The question conducting this research is thus how STI policies in
South Korea have influenced its innovation activity. The results
confirm the existence of multiple structural changes in the series of
patent applications resulting from alternative STI policies
implemented during these years.
Abstract: Enzyme activity was evaluated in the intestine of
juvenile dourado (Salminus brasiliensis) fed with diets containing 0,
10 or 20% of lyophilized bovine colostrum (LBC) inclusion for either
30 or 60 days. The intestinal enzymes acid and alkaline phosphatase
(ACP and ALP, respectively), non-specific esterase (NSE), lipase
(LIP), dipeptidyl aminopeptidase IV (DAP IV) and leucine
aminopeptidase (LAP) were studied using histochemistry in four
intestinal segments (S1, S2, S3 and posterior intestine). Weak
proteolitic activity was observed in all intestinal segments for DAP
IV and LAP. The activity of NSE and LIP was also weak in all
intestines, except for the moderate activity of NSE in the S2 of 20%
LBC group after 30 days and in the S1 of 0% LBC group after 60
days. The ACP was detected only in the S2 and S3 of the 10% LBC
group after 30 days. Moderate and strong staining was observed in
the first three intestinal segments for ALP and weak activity in the
posterior intestine. The activity of DAP IV, LAP and ALP were also
present in the cytoplasm of the enterocytes. In the present results,
bovine colostrum feeding did not cause alterations in activity of
intestinal enzymes.
Abstract: Bureaucracy reform program drives Indonesian
government to change their management to enhance their
organizational performance. Information technology became one of
strategic plan that organization tried to improve. Knowledge
management system is one of information system that supporting
knowledge management implementation in government which
categorized as people perspective, because this system has high
dependency in human interaction and participation. Strategic plan for
developing knowledge management system can be determine using
some of information system strategic methods. This research
conducted to define type of strategic method of information system,
stage of activity each method, strength and weakness. Literature
review methods used to identify and classify strategic methods of
information system, differentiate method type, categorize common
activities, strength and weakness. Result of this research are
determine and compare six strategic information system methods,
Balanced Scorecard and Risk Analysis believe as common strategic
method that usually used and have the highest excellence strength.