Abstract: This study evaluated the acute toxicity and tissue
distribution of intravenously administered gold nanoparticles
(AuNPs) in male rabbits. Rabbits were exposed to single dose of
AuNPs (300 μg/ kg). Toxic effects were assessed via general
behavior, hematological parameters, serum biochemical parameters,
and histopathological examination of various rabbits’ organs.
Inductively coupled plasma–mass spectrometry (ICP-MS) was used
to determine gold concentrations in tissue samples collected at
predetermined time intervals. After one week, AuNPs exerted no
obvious acute toxicity in rabbits. However, inflammatory reactions
were observed in liver, lungs and kidneys accompanied with mild
absolute neutrophilia and significant monocytosis. The highest gold
levels were found in the spleen and liver followed by lungs, and
kidneys. These results indicated that AuNPs could be distributed
extensively to various tissues in the body, but primarily in the spleen
and liver.
Abstract: This study investigates how the site specific traffic
data differs from the Mechanistic Empirical Pavement Design
Software default values. Two Weigh-in-Motion (WIM) stations were
installed in Interstate-40 (I-40) and Interstate-25 (I-25) to developed
site specific data. A computer program named WIM Data Analysis
Software (WIMDAS) was developed using Microsoft C-Sharp (.Net)
for quality checking and processing of raw WIM data. A complete
year data from November 2013 to October 2014 was analyzed using
the developed WIM Data Analysis Program. After that, the vehicle
class distribution, directional distribution, lane distribution, monthly
adjustment factor, hourly distribution, axle load spectra, average
number of axle per vehicle, axle spacing, lateral wander distribution,
and wheelbase distribution were calculated. Then a comparative
study was done between measured data and AASHTOWare default
values. It was found that the measured general traffic inputs for I-40
and I-25 significantly differ from the default values.
Abstract: In this paper, approach to incoherent signal detection
in multi-element antenna array are researched and modeled. Two
types of useful signals with unknown wavefront were considered:
first one, deterministic (Barker code), and second one, random
(Gaussian distribution). The derivation of the sufficient statistics took
into account the linearity of the antenna array. The performance
characteristics and detecting curves are modeled and compared for
different useful signals parameters and for different number of
elements of the antenna array. Results of researches in case of some
additional conditions can be applied to a digital communications
systems.
Abstract: We present probabilistic multinomial Dirichlet
classification model for multidimensional data and Gaussian process
priors. Here, we have considered efficient computational method that
can be used to obtain the approximate posteriors for latent variables
and parameters needed to define the multiclass Gaussian process
classification model. We first investigated the process of inducing a
posterior distribution for various parameters and latent function by
using the variational Bayesian approximations and important sampling
method, and next we derived a predictive distribution of latent
function needed to classify new samples. The proposed model is
applied to classify the synthetic multivariate dataset in order to verify
the performance of our model. Experiment result shows that our model
is more accurate than the other approximation methods.
Abstract: In this study, the time-dependent behavior of damaged
reinforced concrete shear wall structures strengthened with composite
plates having variable fibers spacing was investigated to analyze their
seismic response. In the analytical formulation, the adherent and the
adhesive layers are all modeled as shear walls, using the mixed Finite
Element Method (FEM). The anisotropic damage model is adopted to
describe the damage extent of the Reinforced Concrete shear walls.
The phenomenon of creep and shrinkage of concrete has been
determined by Eurocode 2. Large earthquakes recorded in Algeria
(El-Asnam and Boumerdes) have been tested to demonstrate the
accuracy of the proposed method. Numerical results are obtained for non-uniform distributions of
carbon fibers in epoxy matrices. The effects of damage extent and the
delay mechanism creep and shrinkage of concrete are highlighted.
Prospects are being studied.
Abstract: In this paper, we propose the variational EM inference
algorithm for the multi-class Gaussian process classification model
that can be used in the field of human behavior recognition. This
algorithm can drive simultaneously both a posterior distribution of a
latent function and estimators of hyper-parameters in a Gaussian
process classification model with multiclass. Our algorithm is based
on the Laplace approximation (LA) technique and variational EM
framework. This is performed in two steps: called expectation and
maximization steps. First, in the expectation step, using the Bayesian
formula and LA technique, we derive approximately the posterior
distribution of the latent function indicating the possibility that each
observation belongs to a certain class in the Gaussian process
classification model. Second, in the maximization step, using a derived
posterior distribution of latent function, we compute the maximum
likelihood estimator for hyper-parameters of a covariance matrix
necessary to define prior distribution for latent function. These two
steps iteratively repeat until a convergence condition satisfies.
Moreover, we apply the proposed algorithm with human action
classification problem using a public database, namely, the KTH
human action data set. Experimental results reveal that the proposed
algorithm shows good performance on this data set.
Abstract: For the last decade, researchers have started to focus
their interest on Multicast Group Key Management Framework. The
central research challenge is secure and efficient group key
distribution. The present paper is based on the Bit model based
Secure Multicast Group key distribution scheme using the most
popular absolute encoder output type code named Gray Code. The
focus is of two folds. The first fold deals with the reduction of
computation complexity which is achieved in our scheme by
performing fewer multiplication operations during the key updating
process. To optimize the number of multiplication operations, an
O(1) time algorithm to multiply two N-bit binary numbers which
could be used in an N x N bit-model of reconfigurable mesh is used
in this proposed work. The second fold aims at reducing the amount
of information stored in the Group Center and group members while
performing the update operation in the key content. Comparative
analysis to illustrate the performance of various key distribution
schemes is shown in this paper and it has been observed that this
proposed algorithm reduces the computation and storage complexity
significantly. Our proposed algorithm is suitable for high
performance computing environment.
Abstract: Liver segmentation from medical images poses more
challenges than analogous segmentations of other organs. This
contribution introduces a liver segmentation method from a series of
computer tomography images. Overall, we present a novel method for
segmenting liver by coupling density matching with shape priors.
Density matching signifies a tracking method which operates via
maximizing the Bhattacharyya similarity measure between the
photometric distribution from an estimated image region and a model
photometric distribution. Density matching controls the direction of
the evolution process and slows down the evolving contour in regions
with weak edges. The shape prior improves the robustness of density
matching and discourages the evolving contour from exceeding liver’s
boundaries at regions with weak boundaries. The model is
implemented using a modified distance regularized level set (DRLS)
model. The experimental results show that the method achieves a
satisfactory result. By comparing with the original DRLS model, it is
evident that the proposed model herein is more effective in addressing
the over segmentation problem. Finally, we gauge our performance of
our model against matrices comprising of accuracy, sensitivity, and
specificity.
Abstract: The practical efficient approach is suggested for
estimation of the seismoacoustic sources energy in C-OTDR
monitoring systems. This approach is represents the sequential plan
for confidence estimation both the seismoacoustic sources energy, as
well the absorption coefficient of the soil. The sequential plan
delivers the non-asymptotic guaranteed accuracy of obtained
estimates in the form of non-asymptotic confidence regions with
prescribed sizes. These confidence regions are valid for a finite
sample size when the distributions of the observations are unknown.
Thus, suggested estimates are non-asymptotic and nonparametric,
and also these estimates guarantee the prescribed estimation accuracy
in form of prior prescribed size of confidence regions, and prescribed
confidence coefficient value.
Abstract: The effects of the contact ball-lens on the soda lime
glass in laser thermal cleavage with a cw Nd-YAG laser were
investigated in this study. A contact ball-lens was adopted to generate
a bending force on the crack formation of the soda-lime glass in the
laser cutting process. The Nd-YAG laser beam (wavelength of 1064
nm) was focused through the ball-lens and transmitted to the soda-lime
glass, which was coated with a carbon film on the surface with a
bending force from a ball-lens to generate a tensile stress state on the
surface cracking. The fracture was controlled by the contact ball-lens
and a straight cutting was tested to demonstrate the feasibility.
Experimental observations on the crack propagation from the leading
edge, main section and trailing edge of the glass sheet were compared
with various mechanical and thermal loadings. Further analyses on the
stress under various laser powers and contact ball loadings were made
to characterize the innovative technology. The results show that the distributions of the side crack at the
leading and trailing edges are mainly dependent on the boundary
condition, contact force, cutting speed and laser power. With the
increase of the mechanical and thermal loadings, the region of the side
cracks might be dramatically reduced with proper selection of the
geometrical constrains. Therefore the application of the contact
ball-lens is a possible way to control the fracture in laser cleavage with
improved cutting qualities.
Abstract: A solar receiver is designed for operation under
extremely uneven heat flux distribution, cyclic weather, and cloud
transient cycle conditions, which can include large thermal stress and
even receiver failure. In this study, the effect of different oil velocity
on convection coefficient factor and impact of wind velocity on local
Nusselt number by Finite Volume Method will be analyzed. This
study is organized to give an overview of the numerical modeling
using a MATLAB software, as an accurate, time efficient and
economical way of analyzing the heat transfer trends over stationary
receiver tube for different Reynolds number. The results reveal when
oil velocity is below 0.33m/s, the value of convection coefficient is
negligible at low temperature. The numerical graphs indicate that
when oil velocity increases up to 1.2 m/s, heat convection coefficient
increases significantly. In fact, a reduction in oil velocity causes a
reduction in heat conduction through the glass envelope. In addition,
the different local Nusselt number is reduced when the wind blows
toward the concave side of the collector and it has a significant effect
on heat losses reduction through the glass envelope.
Abstract: Background: Maintaining the correct body balance is
essential in the prevention of falls in the elderly, which is especially
important for women because of postmenopausal osteoporosis and
the serious consequences of falls. One of the exercise methods which
is very popular among adults, and which may affect body balance in
the positive way is the Pilates method. The aim of the study was to
evaluate the effect of regular Pilates exercises on the ability to
maintain body balance in static conditions in adult healthy women.
Material and methods: The study group consisted of 20 healthy
women attending Pilates twice a week for at least 1 year. The control
group consisted of 20 healthy women physically inactive. Women in
the age range from 35 to 50 years old without pain in musculoskeletal
system or other pain were only qualified to the groups. Body balance
was assessed using MatScan VersaTek platform with Sway Analysis
Module based on Matscan Clinical 6.7 software (Tekscan Inc.,
U.S.A). The balance was evaluated under the following conditions:
standing on both feet with eyes open, standing on both feet with eyes
closed, one-leg standing (separately on the right and left foot) with
eyes open. Each test lasted 30 seconds. The following parameters
were calculated: estimated size of the ellipse of 95% confidence, the
distance covered by the Center of Gravity (COG), the size of the
maximum shift in the sagittal and frontal planes and load distribution
between the left and right foot, as well as between rear- and forefoot.
Results: It was found that there is significant difference between the
groups in favor of the study group in the size of the confidence
ellipse and maximum shifts of COG in the sagittal plane during
standing on both feet, both with the eyes open and closed (p
Abstract: The purposes of hydraulic gate are to maintain the
functions of storing and draining water. It bears long-term hydraulic
pressure and earthquake force and is very important for reservoir and
waterpower plant. The high tensile strength of steel plate is used as
constructional material of hydraulic gate. The cracks and rusts,
induced by the defects of material, bad construction and seismic
excitation and under water respectively, thus, the mechanics
phenomena of gate with crack are probing into the cause of stress
concentration, induced high crack increase rate, affect the safety and
usage of hydroelectric power plant. Stress distribution analysis is a
very important and essential surveying technique to analyze
bi-material and singular point problems. The finite difference
infinitely small element method has been demonstrated, suitable for
analyzing the buckling phenomena of welding seam and steel plate
with crack. Especially, this method can easily analyze the singularity
of kink crack. Nevertheless, the construction form and deformation
shape of some gates are three-dimensional system. Therefore, the
three-dimensional Digital Image Correlation (DIC) has been
developed and applied to analyze the strain variation of steel plate with
crack at weld joint. The proposed Digital image correlation (DIC)
technique is an only non-contact method for measuring the variation of
test object. According to rapid development of digital camera, the cost
of this digital image correlation technique has been reduced.
Otherwise, this DIC method provides with the advantages of widely
practical application of indoor test and field test without the restriction
on the size of test object. Thus, the research purpose of this research is
to develop and apply this technique to monitor mechanics crack
variations of weld steel hydraulic gate and its conformation under
action of loading. The imagines can be picked from real time
monitoring process to analyze the strain change of each loading stage.
The proposed 3-Dimensional digital image correlation method,
developed in the study, is applied to analyze the post-buckling
phenomenon and buckling tendency of welded steel plate with crack.
Then, the stress intensity of 3-dimensional analysis of different
materials and enhanced materials in steel plate has been analyzed in
this paper. The test results show that this proposed three-dimensional
DIC method can precisely detect the crack variation of welded steel
plate under different loading stages. Especially, this proposed DIC
method can detect and identify the crack position and the other flaws
of the welded steel plate that the traditional test methods hardly detect
these kind phenomena. Therefore, this proposed three-dimensional
DIC method can apply to observe the mechanics phenomena of
composite materials subjected to loading and operating.
Abstract: A Multi-dimensional computational fluid dynamics
(CFD) two-phase model was developed with the aim to simulate
the in-core coolant circuit of a pressurized heavy water reactor
(PHWR) of a commercial nuclear power plant (NPP). Due to the
fact that this PHWR is a Reactor Pressure Vessel type (RPV),
three-dimensional (3D) detailed modelling of the large reservoirs of
the RPV (the upper and lower plenums and the downcomer) were
coupled with an in-house finite volume one-dimensional (1D) code
in order to model the 451 coolant channels housing the nuclear fuel.
Regarding the 1D code, suitable empirical correlations for taking into
account the in-channel distributed (friction losses) and concentrated
(spacer grids, inlet and outlet throttles) pressure losses were used.
A local power distribution at each one of the coolant channels
was also taken into account. The heat transfer between the coolant
and the surrounding moderator was accurately calculated using a
two-dimensional theoretical model. The implementation of subcooled
boiling and condensation models in the 1D code along with the use
of functions for representing the thermal and dynamic properties of
the coolant and moderator (heavy water) allow to have estimations
of the in-core steam generation under nominal flow conditions for a
generic fission power distribution. The in-core mass flow distribution
results for steady state nominal conditions are in agreement with the
expected from design, thus getting a first assessment of the coupled
1/3D model. Results for nominal condition were compared with
those obtained with a previous 1/3D single-phase model getting more
realistic temperature patterns, also allowing visualize low values of
void fraction inside the upper plenum. It must be mentioned that the
current results were obtained by imposing prescribed fission power
functions from literature. Therefore, results are showed with the aim
of point out the potentiality of the developed model.
Abstract: In this study, static and dynamic responses of a typical
reinforced concrete solid slab, designed to British Standard (BS 8110:
1997) and under self and live loadings for dance halls are reported.
Linear perturbation analysis using finite element method was
employed for modal, impulse loading and frequency response
analyses of the slab under the aforementioned loading condition.
Results from the static and dynamic analyses, comprising of the slab
fundamental frequencies and mode shapes, dynamic amplification
factor, maximum deflection, stress distributions among other
valuable outcomes are presented and discussed. These were gauged
with the limiting provisions in the design code with a view of
justifying valid optimization objective function for the structure that
can ensure both adequate strength and economical section for large
clear span slabs. This is necessary owing to the continued increase in
cost of erecting building structures and the squeeze on public finance
globally.
Abstract: Polycyclic Aromatic Hydrocarbons (PAHs) are
formed mainly because of incomplete combustion of organic
materials during industrial, domestic activities or natural occurrence.
Their toxicity and contamination of terrestrial and aquatic ecosystem
have been established. However, with limited validity index, previous
research has focused on PAHs isomer pair ratios of variable
physicochemical properties in source identification. The objective of
this investigation was to determine the empirical validity of Pearson
Correlation Coefficient (PCC) and Cluster Analysis (CA) in PAHs
source identification along soil samples of different land uses.
Therefore, 16 PAHs grouped, as Endocrine Disruption Substances
(EDSs) were determined in 10 sample stations in top and sub soils
seasonally. PAHs was determined the use of Varian 300 gas
chromatograph interfaced with flame ionization detector. Instruments
and reagents used are of standard and chromatographic grades
respectively. PCC and CA results showed that the classification of
PAHs along pyrolitic and petrogenic organics used in source
signature is about the predominance PAHs in environmental matrix.
Therefore, the distribution of PAHs in the studied stations revealed
the presence of trace quantities of the vast majority of the sixteen
PAHs, which may ultimately inhabit the actual source signature
authentication. Therefore, factors to be considered when evaluating
possible sources of PAHs could be; type and extent of bacterial
metabolism, transformation products/substrates, and environmental
factors such as salinity, pH, oxygen concentration, nutrients, light
intensity, temperature, co-substrates, and environmental medium are
hereby recommended as factors to be considered when evaluating
possible sources of PAHs.
Abstract: Non-linear dynamic time history analysis is
considered as the most advanced and comprehensive analytical
method for evaluating the seismic response and performance of
multi-degree-of-freedom building structures under the influence of
earthquake ground motions. However, effective and accurate
application of the method requires the implementation of advanced
hysteretic constitutive models of the various structural components
including masonry infill panels. Sophisticated computational research
tools that incorporate realistic hysteresis models for non-linear
dynamic time-history analysis are not popular among the professional
engineers as they are not only difficult to access but also complex and
time-consuming to use. In addition, commercial computer programs
for structural analysis and design that are acceptable to practicing
engineers do not generally integrate advanced hysteretic models
which can accurately simulate the hysteresis behavior of structural
elements with a realistic representation of strength degradation,
stiffness deterioration, energy dissipation and ‘pinching’ under cyclic
load reversals in the inelastic range of behavior. In this scenario,
push-over or non-linear static analysis methods have gained
significant popularity, as they can be employed to assess the seismic
performance of building structures while avoiding the complexities
and difficulties associated with non-linear dynamic time-history
analysis. “Push-over” or non-linear static analysis offers a practical
and efficient alternative to non-linear dynamic time-history analysis
for rationally evaluating the seismic demands. The present paper is
based on the analytical investigation of the effect of distribution of
masonry infill panels over the elevation of planar masonry infilled
reinforced concrete [R/C] frames on the seismic demands using the
capacity spectrum procedures implementing nonlinear static analysis
[pushover analysis] in conjunction with the response spectrum
concept. An important objective of the present study is to numerically
evaluate the adequacy of the capacity spectrum method using
pushover analysis for performance based design of masonry infilled
R/C frames for near-field earthquake ground motions.
Abstract: An early diagnosis of bone metastasis is very
important for making a right decision on a subsequent therapy. One
of the most important steps to be taken initially, for developing a new
radiopharmaceutical is the measurement of organ radiation exposure
dose. In this study, the dosimetric studies of a novel agent for
SPECT-imaging of the bone metastasis, 111In-(4-
{[(bis(phosphonomethyl))carbamoyl]methyl}7,10bis(carboxymethyl)
-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (111In-BPAMD)
complex, have been carried out to estimate the dose in human organs
based on the data derived from mice. The radiolabeled complex was
prepared with high radiochemical purity in the optimal conditions.
Biodistribution studies of the complex was investigated in the male
Syrian mice at the selected times after injection (2, 4, 24 and 48 h).
The human absorbed dose estimation of the complex was made based
on data derived from the mice by the radiation absorbed dose
assessment resource (RADAR) method. 111In-BPAMD complex was prepared with high radiochemical
purity >95% (ITLC) and specific activities of 2.85 TBq/mmol. Total
body effective absorbed dose for 111In-BPAMD was 0.205
mSv/MBq. This value is comparable to the other 111In clinically used
complexes. The results show that the dose with respect to the critical
organs is satisfactory within the acceptable range for diagnostic
nuclear medicine procedures. Generally, 111In-BPAMD has
interesting characteristics and it can be considered as a viable agent
for SPECT-imaging of the bone metastasis in the near future.
Abstract: In this article, we used the residual correction method
to deal with transient thermoelastic problems with a hollow spherical
region when the continuum medium possesses spherically isotropic
thermoelastic properties. Based on linear thermoelastic theory, the
equations of hyperbolic heat conduction and thermoelastic motion
were combined to establish the thermoelastic dynamic model with
consideration of the deformation acceleration effect and non-Fourier
effect under the condition of transient thermal shock. The approximate
solutions of temperature and displacement distributions are obtained
using the residual correction method based on the maximum principle
in combination with the finite difference method, making it easier and
faster to obtain upper and lower approximations of exact solutions.
The proposed method is found to be an effective numerical method
with satisfactory accuracy. Moreover, the result shows that the effect
of transient thermal shock induced by deformation acceleration is
enhanced by non-Fourier heat conduction with increased peak stress.
The influence on the stress increases with the thermal relaxation time.
Abstract: Abstract—[Tris (1,10-phenanthroline) lanthanum(III)]
trithiocyanate is a new compound that has shown high ability for
stopping the synthesis of DNA and also acting as a photosensitizer.
Nowadays, the radiation dose assessment resource (RADAR) method
is known as the most common method for absorbed dose calculation.
177Lu was produced by (n, gamma) reaction in a research reactor.
177Lu-PL3 was prepared in the optimized condition. The
radiochemical yield was checked by ITLC method. The
biodistribution of the complex was investigated by intravenously
injection to wild-type rats via their tail veins. In this study, the
absorbed dose of 177Lu-PL3 to human organs was estimated by
RADAR method. 177Lu was prepared with a specific activity of 2.6-3
GBq.mg-1 and radionuclide purity of 99.98 %. Final preparation of
the radiolabelled complex showed high radiochemical purity of >
99%. The results show that liver and spleen have received the highest
absorbed dose of 1.051 and 0.441 mSv/MBq, respectively. The
absorbed dose values for these two dose-limiting tissues suggest
more biological studies special in tumor-bearing animals.