Abstract: This study aimed to determine the possible protective effects of L‐carnitine against gentamicin‐induced nephrotoxicity. Forty male albino rats were divided into 4 groups (10 rats each); Group 1: normal control, group 2: induced nephrotoxicity (gentamicin 50 mg/kg/day S.C; 8 days), group 3: treated with L‐ carnitine (40 mg/kg/d SC for 12 days) and group 4: treated with L‐ carnitine 4 days before and for 8 days in concomitant with gentamicin. Gentamicin‐induced nephrotoxicity (group 2): caused significant increase in serum urea, creatinine, urinary N‐acetyl‐B‐D‐ glucosaminidase (NAG), gamma glutamyl transpeptidase (GGT), urinary total protein and kidney tissue malondialdehyde (MDA) with significant decrease in serum superoxide dismutase (SOD), serum catalase and creatinine clearance and marked tubular necrosis in the proximal convoluted tubules with interruption in the basement membrane around the necrotic tubule compared to the normal control group. L‐carnitine 4 days before and for 8 days in concomitant with gentamicin (group 4) offered marked decrease in serum urea, serum creatinine, urinary NAG, urinary GGT, urinary proteins and kidney tissue MDA, with marked increase in serum SOD, serum catalase and creatinine clearance with marked improvement in the tubular damage compared to gentamicin‐induced nephrotoxicity group. L‐carnitine administered for 12 days produced no change in the parameters mentioned above as compared to the normal control group. In conclusion: L‐carnitine could reduce most of the biochemical parameters and also improve the histopathological features of kidney asscociated with gentamicin induced‐nephrotoxicity.
Abstract: Riveting process is one of the important ways to keep
fastening the lap joints in aircraft structures. Failure of aircraft lap
joints directly depends on the stress field in the joint. An important
application of riveting process is in the construction of aircraft
fuselage structures. In this paper, a 3D finite element method is
carried out in order to optimize residual stress field in a riveted lap
joint and also to estimate its fatigue life. In continue, a number of
experiments are designed and analyzed using design of experiments
(DOE). Then, Taguchi method is used to select an optimized case
between different levels of each factor. Besides that, the factor which
affects the most on residual stress field is investigated. Such
optimized case provides the maximum residual stress field. Fatigue
life of the optimized joint is estimated by Paris-Erdogan law. Stress
intensity factors (SIFs) are calculated using both finite element
analysis and experimental formula. In addition, the effect of residual
stress field, geometry and secondary bending are considered in SIF
calculation. A good agreement is found between results of such
methods. Comparison between optimized fatigue life and fatigue life
of other joints has shown an improvement in the joint’s life.
Abstract: Obesity and osteoporosis are the two diseases whose
increasing prevalence and high impact on the global morbidity and
mortality, during the two recent decades, have gained a status of
major health threats worldwide. Obesity purports to affect the bone
metabolism through complex mechanisms. Debated data on the
connection between the bone mineral density and fracture prevalence
in the obese patients are widely presented in literature. There is
evidence that the correlation of weight and fracture risk is sitespecific.
This study is aimed at determining the connection between
the bone mineral density (BMD) and trabecular bone score (TBS)
parameters in Ukrainian women suffering from obesity. We
examined 1025 40-89-year-old women, divided them into the groups
according to their body mass index: Group A included 360 women
with obesity whose BMI was ≥30 kg/m2, and Group B – 665 women
with no obesity and BMI of
Abstract: The flow duration curve (FDC) is an informative
method that represents the flow regime’s properties for a river basin.
Therefore, the FDC is widely used for water resource projects such as
hydropower, water supply, irrigation and water quality management.
The primary purpose of this study is to obtain synthetic daily flow
duration curves for Çoruh Basin, Turkey. For this aim, we firstly
developed univariate auto-regressive moving average (ARMA)
models for daily flows of 9 stations located in Çoruh basin and then
these models were used to generate 100 synthetic flow series each
having same size as historical series. Secondly, flow duration curves
of each synthetic series were drawn and the flow values exceeded 10,
50 and 95% of the time and 95% confidence limit of these flows were
calculated. As a result, flood, mean and low flows potential of Çoruh
basin will comprehensively be represented.
Abstract: The security of cloud services is the concern of cloud
service providers. In this paper, we will mention different
classifications of cloud attacks referred by specialized organizations.
Each agency has its classification of well-defined properties. The
purpose is to present a high-level classification of current research in
cloud computing security. This classification is organized around
attack strategies and corresponding defenses.
Abstract: Knowledge of bone mechanical properties is important
for bone substitutes design and fabrication, and more efficient
prostheses development. The aim of this study is to characterize the
viscoelastic behavior of bone specimens, through stress relaxation
and fatigue tests performed to trabecular bone samples from bovine
femoral heads. Relaxation tests consisted on preloading the samples
at five different magnitudes and evaluate them for 1020 seconds,
adjusting the results to a KWW mathematical model. Fatigue tests
consisted of 700 load cycles and analyze their status at the end of the
tests. As a conclusion we have that between relaxation stress and
each preload there is linear relation and for samples with initial
Young´s modulus greater than 1.5 GPa showed no effects due fatigue
test loading cycles.
Abstract: Current research is targeting new molecular
mechanisms that underlie non-alcoholic fatty liver disease (NAFLD)
and associated metabolic disorders like non-alcoholic steatohepatitis
(NASH). Forty New Zealand White rabbits have been used and fed a
high protein (HP) and energy diet based on grains and containing
11.76 MJ/kg. Boron added to 3 experimental groups’ drinking waters
(30 mg boron/L) as boron compounds. Biochemical analysis
including boron levels, and nuclear magnetic resonance (NMR) based
metabolomics evaluation, and mRNA expression of peroxisome
proliferator-activated receptor (PPAR) family was performed. LDLcholesterol
concentrations alone were decreased in all the
experimental groups. Boron levels in serum and feces were increased.
Content of acetate was in about 2x higher for anhydrous borax group,
at least 3x higher for boric acid group. PPARα mRNA expression
was significantly decreased in boric acid group. Anhydrous borax
attenuated mRNA levels of PPARγ, which was further suppressed by
boric acid. Boron supplementation decreased the degenerative
alterations in hepatocytes. Except borax group other boron groups did
not have a pronounced change in tubular epithels of kidney. In
conclusion, high protein and energy diet leads hepatocytes’
degenerative changes which can be prevented by boron
supplementation. Boric acid seems to be more effective in this
situation.
Abstract: Optimal feeding, including optimal micronutrient
intake, becomes one of the ways to overcome the long-term
consequences of undernutrition. Macronutrient and micronutrient
intake were important to a rapid growth and development of young
children. The study objective was to assess macro and micronutrient
intake and its adequacy in children aged 12-23 months. This survey
was a cross-sectional study, involving 83 caregivers with children
aged 12-23 months old in Senen Sub-district, Central Jakarta selected
through simple random sampling. Data on nutrient intake was
obtained through interview using single 24-hour recall. Repeated 24-
hour recall to sub-sample was done to estimate the proportion of
nutrient inadequacy. The highest prevalence of nutrient inadequacy
was iron (52.4%), followed by vitamin C (30.9%) and zinc (28.8%).
Almost 12% children had inadequate energy intake. More than half
of children (62.6%) were anemic (25.3% were severely anemic).
Micronutrient inadequacy, especially iron, was more problematic
than macronutrient inadequacy in the study area.
Abstract: This paper discusses the forensic investigation of a
fatality-involved catastrophic structure collapse and the special
challenges faced when tasked with directing such an effort. While
this paper discusses the investigation’s findings and the outcome of
the event; this paper’s primary focus is on the challenges faced
directing a forensic investigation that requires coordinating with
governmental oversight while also having to accommodate multiple
parties’ investigative teams. In particular the challenges discussed
within this paper included maintaining on-site safety and operations
while accommodating outside investigator’s interests. In addition this
paper discusses unique challenges that one may face such as what to
do about unethical conduct of interested party’s investigative teams,
“off the record” sharing of information, and clandestinely transmitted
evidence.
Abstract: Driver fatigue is an important factor in the increasing
number of road accidents. Dynamic template matching method was
proposed to address the problem of real-time driver fatigue detection
system based on eye-tracking. An effective vision based approach
was used to analyze the driver’s eye state to detect fatigue. The driver
fatigue system consists of Face detection, Eye detection, Eye
tracking, and Fatigue detection. Initially frames are captured from a
color video in a car dashboard and transformed from RGB into YCbCr
color space to detect the driver’s face. Canny edge operator was used
to estimating the eye region and the locations of eyes are extracted.
The extracted eyes were considered as a template matching for eye
tracking. Edge Map Overlapping (EMO) and Edge Pixel Count
(EPC) matching function were used for eye tracking which is used to
improve the matching accuracy. The pixel of eyeball was tracked
from the eye regions which are used to determine the fatigue state of
the driver.
Abstract: Some plants of genus Schinus have been used in the
folk medicine as topical antiseptic, digestive, purgative, diuretic,
analgesic or antidepressant, and also for respiratory and urinary
infections. Chemical composition of essential oils of S. molle and S.
terebinthifolius had been evaluated and presented high variability
according with the part of the plant studied and with the geographic
and climatic regions. The pharmacological properties, namely
antimicrobial, anti-tumoural and anti-inflammatory activities are
conditioned by chemical composition of essential oils. Taking into
account the difficulty to infer the pharmacological properties of
Schinus essential oils without hard experimental approach, this work
will focus on the development of a decision support system, in terms
of its knowledge representation and reasoning procedures, under a
formal framework based on Logic Programming, complemented with
an approach to computing centered on Artificial Neural Networks
and the respective Degree-of-Confidence that one has on such an
occurrence.
Abstract: The fatigue life of tubular joints commonly found in
offshore industry is not only dependent on the value of hot-spot stress
(HSS), but is also significantly influenced by the through-thethickness
stress distribution characterized by the degree of bending
(DoB). The determination of DoB values in a tubular joint is essential
for improving the accuracy of fatigue life estimation using the stresslife
(S–N) method and particularly for predicting the fatigue crack
growth based on the fracture mechanics (FM) approach. In the
present paper, data extracted from finite element (FE) analyses of
tubular KT-joints, verified against experimental data and parametric
equations, was used to investigate the effects of geometrical
parameters on DoB values at the crown 0°, saddle, and crown 180°
positions along the weld toe of central brace in tubular KT-joints
subjected to axial loading. Parametric study was followed by a set of
nonlinear regression analyses to derive DoB parametric formulas for
the fatigue analysis of KT-joints under axial loads. The tubular KTjoint
is a quite common joint type found in steel offshore structures.
However, despite the crucial role of the DoB in evaluating the fatigue
performance of tubular joints, this paper is the first attempt to study
and formulate the DoB values in KT-joints.
Abstract: An important problem for the CaSO4/CaSO4・1/2H2O
Chemical heat pump (CHP) is that the material is deactivated through
repetitive reaction between hydration and dehydration in which the
crystal phase of the material is transformed from III-CaSO4 to
II-CaSO4. We investigated suppression on the phase change by adding
a sulfated compound. The most effective material was MgSO4. MgSO4
doping increased the durability of CaSO4 in the actual CHP repetitive
cycle of hydration/dehydration to 3.6 times that of undoped CaSO4.
The MgSO4-doped CaSO4 showed a higher phase transition
temperature and activation energy for crystal transformation from
III-CaSO4 to II-CaSO4. MgSO4 doping decreased the crystal lattice
size of CaSO4・1/2H2O and II-CaSO4 to smaller than that of undoped
CaSO4. Modification of the crystal structure is considered to be related
to the durability change in CaSO4 resulting from MgSO4 doping.
Abstract: Transportation of long turbine blades from one place
to another is a difficult process. Hence a feasibility study of
modularization of wind turbine blade was taken from structural
standpoint through finite element analysis. Initially, a non-segmented
blade is modeled and its structural behavior is evaluated to serve as
reference. The resonant, static bending and fatigue tests are simulated
in accordance with IEC61400-23 standard for comparison purpose.
The non-segmented test blade is separated at suitable location based
on trade off studies and the segments are joined with an innovative
double strap bonded joint configuration. The adhesive joint is
modeled by adopting cohesive zone modeling approach in ANSYS.
The developed blade model is analyzed for its structural response
through simulation. Performances of both the blades are found to be
similar, which indicates that, efficient segmentation of the long blade
is possible which facilitates easy transportation of the blades and on
site reassembling. The location selected for segmentation and
adopted joint configuration has resulted in an efficient segmented
blade model which proves the methodology adopted for segmentation
was quite effective. The developed segmented blade appears to be the
viable alternative considering its structural response specifically in
fatigue within considered assumptions.
Abstract: Background: Worldwide, at least 2.8 million people
die each year as a result of being overweight or obese, and 35.8
million (2.3%) of global DALYs are caused by overweight or
obesity. Obesity is acknowledged as one of the burning public
health problems reducing life expectancy and quality of life. The
body composition analysis of the university population is essential
in assessing the nutritional status, as well as the risk of developing
diseases associated with abnormal body fat content so as to make
nutritional recommendations. Objectives: The main aim was to
determine the prevalence of obesity and overweight in University
students using Anthropometric analysis and BIA methods. Material
and Methods: In this cross-sectional study, 283 university students
participated. The body composition analysis was undertaken by
using mainly: i) Anthropometric Measurement: Height, Weight,
BMI, waist circumference, hip circumference and skin fold
thickness, ii) Bio-electrical impedance was used for analysis of
body fat mass, fat percent and visceral fat which was measured by
Tanita SC-330P Professional Body Composition Analyzer. The
data so collected were compiled in MS Excel and analyzed for
males and females using SPSS 16. Results and Discussion: The
mean age of the male (n= 153) studied subjects was 25.37 ±2.39
years and females (n=130) was 22.53 ±2.31. The data of BIA
revealed very high mean fat per cent of the female subjects i.e.
30.3±6.5 per cent whereas mean fat per cent of the male subjects
was 15.60±6.02 per cent indicating a normal body fat range. The
findings showed high visceral fat of both males (12.92±3.02) and
females (16.86±4.98). BMI, BF% and WHR were higher among
females, and BMI was higher among males. The most evident
correlation was verified between BF% and WHR for female
students (r=0.902; p
Abstract: A field study was conducted to evaluate the efficacy of
safflower plant for phytoremediation of contaminated soils. The
experiment was performed on an agricultural fields contaminated by
the Non-Ferrous-Metal Works near Plovdiv, Bulgaria. Field
experiments with randomized complete block design with five
treatments (control, compost amendments added at 20 and 40 t/daa,
and vermicompost amendments added at 20 and 40 t/daa) were
carried out. The quality of safflower seeds and oil (heavy metals and
fatty acid composition) were determined. Tested organic amendments
significantly influenced the chemical composition of safflower seeds
and oil. The compost and vermicompost treatments significantly
reduced heavy metals concentration in safflower seeds and oils, but
the effect differed among them. Addition of vermicompost and
compost leads to an increase in the content of palmitic acid and
linoleic acid, and a decrease in the stearic and oleic acids compared
with the control. A significant increase in the quantity of saturated
acids was observed in the variants with 20 t/daa of compost and 20
t/daa of vermicompost (9.1 and 8.9% relative to the control).
Safflower is a plant which is tolerant to heavy metals and can be
successfully used in the phytoremediation of heavy metal
contaminated soils. The processing of seeds to oil and using the
obtained oil for nutritional purposes will greatly reduce the cost of
phytoremediation.
Abstract: In this paper, an analytical simplified method for
calculating elasto-plastic stresses strains of notched bodies subject to
non-proportional loading paths is discussed. The method was based
on the Neuber notch correction, which relates the incremental elastic
and elastic-plastic strain energy densities at the notch root and the
material constitutive relationship. The validity of the method was
presented by comparing computed results of the proposed model
against finite element numerical data of notched shaft. The
comparison showed that the model estimated notch-root elasto-plastic
stresses strains with good accuracy using linear-elastic stresses. The
prosed model provides more efficient and simple analysis method
preferable to expensive experimental component tests and more
complex and time consuming incremental non-linear FE analysis.
The model is particularly suitable to perform fatigue life and fatigue
damage estimates of notched components subjected to nonproportional
loading paths.
Abstract: Egg yolk oil is a natural source of bioactive
compounds such as unsaturated fatty acids, oil soluble vitamins,
pigments and others. Bioactive compound content in egg yolk oil
depends from its content in eggs, from which oil was extracted. Many
studies show that bioactive compound content in egg is correlated to
the content of these compounds in hen feed, but there is also an
opinion that hen housing systems also have influence on egg
chemical content. The aim of this study was to determine which
factor, laying hen housing system or hen diet, has a primary influence
on bioactive compound content in egg yolk oil. The egg yolk oil was
extracted from eggs obtained from 4 different hen housing systems:
cage, barn and two groups of free range. All hens were fed with
commercially produced compound feed except one group of free
range hens which get free diet – pastured hens. Extracted egg yolk
oils were analyzed for fatty acids, oil soluble vitamins and β-carotene
content. α-tocopherol, ergocalcipherol and polyunsaturated fatty acid
content in egg yolk oil was higher from eggs obtained from all
housing systems where hens were fed with commercial compound
feed. β-carotene and retinol content in egg yolk oils from free range
free diet eggs was significantly (p>0.05) higher that from other eggs
because hens have access to green forage. Hen physical activity in
free range housing systems decreases content of some bioactive
compound in egg yolk oil.
Abstract: Breast cancer is considered as a substantial health
concern and practicing mammography screening [MS] is important in
minimizing its related morbidity. So it is essential to have a better
understanding of breast cancer screening behaviors of women and
factors that influence utilization of them. The aim of this study is to
identify the factors that are linked to MS behaviors among the
Egyptian women. A cross-sectional descriptive design was carried
out to provide a snapshot of the factors that are linked to MS
behaviors. A convenience sample of 311 women was utilized and all
eligible participants admitted to the Women Imaging Unit who are 40
years of age or above, coming for mammography assessment, not
pregnant or breast feeding and who accepted to participate in the
study were included. A structured questionnaire was developed by
the researchers and contains three parts; Socio-demographic data;
Motivating factors associated with MS; and association between MS
and model of behavior change. The analyzed data indicated that most
of the participated women (66.6%) belonged to the age group of 40-
49.A high proportion of participants (58.1%) of group having
previous MS influenced by their neighbors to practice MS, whereas
32.7 % in group not having previous MS were influenced by family
members which indicated significant differences (P
Abstract: Turkish migrants constitute the largest group among
people with migration background living in Germany. Turkish
women’s labor market participation is of significant importance for
their social and economic integration to the German society. This
paper thus aims to investigate their labor market positions. Turkish
migrant women participate less in the labor market compared to men,
and are responsible for most of the housework, child care, and elderly
care. This is due to their traditional roles in the family, educational
level, insufficient knowledge of German language, and insufficient
professional experience. We strongly recommend that wide-reaching
integration policies for women are formulated, so as to encourage
participation of not only migrant women but also their husbands,
fathers and/or brothers, and natives.