Abstract: The main cause of Alzheimer disease (AD) was
believed to be mainly due to the accumulation of free radicals owing
to oxidative stress (OS) in brain tissue. The mechanism of the
neurotoxicity of Aluminum chloride (AlCl3) induced AD in
hippocampus Albino wister rat brain tissue, the curative & the
protective effects of Lipidium sativum group (LS) water extract were
assessed after 8 weeks by attenuated total reflection spectroscopy
ATR-IR and histologically by light microscope. ATR-IR results
revealed that the membrane phospholipid undergo free radical
attacks, mediated by AlCl3, primary affects the polyunsaturated fatty
acids indicated by the increased of the olefinic -C=CH sub-band area
around 3012 cm-1 from the curve fitting analysis. The narrowing in
the half band width (HBW) of the sνCH2 sub-band around 2852 cm-1
due to Al intoxication indicates the presence of trans form fatty acids
rather than gauch rotomer. The degradation of hydrocarbon chain to
shorter chain length, increasing in membrane fluidity, disorder, and
decreasing in lipid polarity in AlCl3 group indicated by the detected
changes in certain calculated area ratios compared to the control.
Administration of LS was greatly improved these parameters
compared to the AlCl3 group. Al influences the Aβ aggregation and
plaque formation, which in turn interferes to and disrupts the
membrane structure. The results also showed a marked increase in
the β-parallel and antiparallel structure, that characterize the Aβ
formation in Al-induced AD hippocampal brain tissue, indicated by
the detected increase in both amide I sub-bands around 1674, 1692
cm-1. This drastic increase in Aβ formation was greatly reduced in the
curative and protective groups compared to the AlCl3 group and
approached nearly the control values. These results supported too by
the light microscope. AlCl3 group showed significant marked
degenerative changes in hippocampal neurons. Most cells appeared
small, shrieked and deformed. Interestingly, the administration of LS
in curative and protective groups markedly decreases the amount of
degenerated cells compared to the non-treated group. In addition, the
intensity of congo red stained cells was decreased. Hippocampal
neurons looked more/or less similar to those of control. This study showed a promising therapeutic effect of Lipidium
sativum group (LS) on AD rat model that seriously overcome the
signs of oxidative stress on membrane lipid and restore the protein
misfolding.
Abstract: Many herbal medicinal products are considered
potential anti-hypercholesterolemic agents with encouraging safety
profiles, however only a limited amount of clinical research exists to
support their efficacy. The present study was designed to compare the
antihypercholesterolemic and antioxidant activities of the crude
ethanolic extracts of Citrus reticulata fruit peel, Zingiber officinale
rhizome and Sesamum indicum seeds. Forty-five rats were used throughout the experiment which are
extended for four weeks. These were divided into nine groups, five
rats per each group as follows; group 1 was the normal control group
(rats only fed standard normal rat diet), group 2 was the
hypercholesterolemic control group (rats fed only
hypercholesterolemic diet which contained 1% cholesterol plus 10%
saturated animal fat added to the normal rat diet), groups 3 and 4
were fed hypercholesterolemic diet in addition to Citrus reticulata
ethanolic extract at doses of (250mg/kg (group 3) and 500mg/kg
(group 4)) administered daily via oral route, groups 5 and 6 were
given hypercholesterolemic diet in addition to Zingiber officinale
ethanolic extract at doses of (250mg/kg (group 5) and 500mg/kg
(group 6)) daily through oral route, groups 7 and 8 fed on
hypercholesterolemic diet in addition to Sesamum indicum ethanolic
extract at doses of (250mg/kg (group 7) and 500mg/kg (group 8))
daily orally; and group 9 rats were given hypercholesterolemic diet in
addition to atorvastatin (0.18mg/kg) daily via oral route as a standard
reference antihypercholesterolemic drug. Blood samples from all
groups were drawn from the retro-orbital venous plexus four weeks
following treatment after overnight fasting and the lipid profile (total
cholesterol (TC), high density lipoprotein-cholesterol (HDL-C), low
density lipoprotein-cholesterol (LDL-C) and triglyceride levels) were
measured and the risk ratio (TC/HDL-C) was assessed. The
antioxidant activity of the three plants extracts was determined using
DPPH free-radical antioxidant assay. Results of in vivo and in vitro
antihypercholesterolemic and antioxidant assay respectively, revealed
that the three extracts possess comparable antioxidant and
antihypercholesterolemic activities.
Abstract: The goal of this paper is proposing a supply chain
value dashboard in home appliance manufacturing firms to create
more value for all stakeholders via balanced scorecard approach.
Balanced scorecard is an effective approach that managers have used
to evaluate supply chain performance in many fields but there is a
lack of enough attention to all supply chain stakeholders, improving
value creation and, defining correlation between value indicators and
performance measuring quantitatively. In this research the key
stakeholders in home appliance supply chain, value indicators with
respect to create more value for stakeholders and the most important
metrics to evaluate supply chain value performance based on
balanced scorecard approach have been selected via literature review.
The most important indicators based on expert’s judgment acquired
by in survey focused on creating more value for. Structural equation
modelling has been used to disclose relations between value
indicators and balanced scorecard metrics. The important result of
this research is identifying effective value dashboard to create more
value for all stakeholders in supply chain via balanced scorecard
approach and based on an empirical study covering ten home
appliance manufacturing firms in Iran. Home appliance
manufacturing firms can increase their stakeholder's satisfaction by
using this value dashboard.
Abstract: Rapid prototyping is a new group of manufacturing
processes, which allows fabrication of physical of any complexity
using a layer by layer deposition technique directly from a computer
system. The rapid prototyping process greatly reduces the time and
cost necessary to bring a new product to market. The prototypes
made by these systems are used in a range of industrial application
including design evaluation, verification, testing, and as patterns for
casting processes. These processes employ a variety of materials and
mechanisms to build up the layers to build the part. The present work
was to build a FDM prototyping machine that could control the X-Y
motion and material deposition, to generate two-dimensional and
three-dimensional complex shapes. This study focused on the
deposition of wax material. This work was to find out the properties
of the wax materials used in this work in order to enable better
control of the FDM process. This study will look at the integration of
a computer controlled electro-mechanical system with the traditional
FDM additive prototyping process. The characteristics of the wax
were also analysed in order to optimise the model production process.
These included wax phase change temperature, wax viscosity and
wax droplet shape during processing.
Abstract: In recent years, the power system has been changed
and a flexible power pricing system such as demand response has been
sought in Japan. The demand response system works simply in the
household sector and the owner as the decision-maker, can benefit
from power saving. On the other hand, the execution of demand
response in the office building is more complex than in the household
because various people such as owners, building administrators and
occupants are involved in the decision-making process. While the
owners benefit from demand saving, the occupants are exposed to
restricted benefits of a demand-saved environment. One of the reasons
is that building systems are usually under centralized management and
each occupant cannot choose freely whether to participate in demand
response or not. In addition, it is unclear whether incentives give
occupants the motivation to participate. However, the recent
development of IT and building systems enables the personalized
control of the office environment where each occupant can control the
lighting level or temperature individually. Therefore, it can be possible
to have a system which each occupant can make a decision of whether
or not to participate in demand response in the office building. This study investigates personal responses to demand response
requests, under the condition where each occupant can adjust their
brightness individually in their workspace. Once workers participate
in the demand response, their desk-lights are automatically turned off.
The participation rates in the demand response events are compared
among four groups, which are divided by different motivation, the
presence, or absence of incentives and the method of participation. The
result shows that there are significant differences of participation rates
in demand response event between four groups. The method of
participation has a large effect on the participation rate. The “Opt-out”
groups where the occupants are automatically enrolled in a demand
response event if they do not express non-participation have the
highest participation rate in the four groups. Incentives also have an
effect on the participation rate. This study also reports on the impact of low illumination office
environment on the occupants, such as stress or fatigue. The
electrocardiogram and the questionnaire are used to investigate the
autonomic nervous activity and subjective fatigue symptoms of the
occupants. There is no big difference between dim workspace during
demand response event and bright workspace in autonomic nervous
activity and fatigue.
Abstract: On account of the concern of the fossil fuel is
depleting and its negative effects on the environment, interest in
alternative energy sources is increasing day by day. However,
considering the importance of transportation in human life, instead of
oil and its derivatives fueled vehicles with internal combustion
engines, electric vehicles which are sensitive to the environment and
working with electrical energy has begun to develop. In this study,
simulation was carried out for providing energy management and
recovering regenerative braking in fuel cell-battery hybrid electric
vehicle. The main power supply of the vehicle is fuel cell on the other
hand not only instantaneous power is supplied by the battery but also
the energy generated due to regenerative breaking is stored in the
battery. Obtained results of the simulation is analyzed and discussed.
Abstract: The present explanatory study concerns with the
relation between Diabetes Mellitus and Food Balance in the Kingdom
of Saudi Arabia during 2005-2010, using published data. Results illustrated that Saudi citizen daily protein consumption
(DPC) during 2005-2007 (g/capita/day) is higher than the average
global consumption level of protein with 15.27%, daily fat
consumption (DFC) with 24.56% and daily energy consumption
(DEC) with 16.93% and increases than recommended level by
International Nutrition Organizations (INO) with 56% for protein,
60.49% for fat and 27.37% for energy. On the other hand, DPC per
capita in Saudi Arabia decreased during the period 2008-2010 from
88.3 to 82.36 gram/ day. Moreover, DFC per capita in Saudi Arabia
decreased during the period 2008-2010 from 3247.90 to 3176.43
Cal/capita/ day, and daily energy consumption (DEC) of Saudi
citizen increases than world consumption with 16.93%, whereas
increases with 27.37% than INO. Despite this, DPC, DFC and DEC
per capita in Saudi Arabia still higher than world mean. On the other
side, results illustrated that the number of diabetic patients in Saudi
Arabia during the same period (2005-2010). The curve of diabetic
patient’s number in Saudi Arabia during 2005-2010 is regular
ascending with increasing level ranged between 7.10% in 2005 and
12.44% in 2010. It is essential to devise Saudi National programs to educate the
public about the relation of food balances and diabetes so it could be
avoided, and provide citizens with healthy dietary balances tables.
Abstract: Cortisol is essential to the regulation of the immune
system and pathological yawning is a symptom of multiple sclerosis
(MS). Electromyography activity (EMG) in the jaw muscles typically
rises when the muscles are moved – extended or flexed; and yawning
has been shown to be highly correlated with cortisol levels in healthy
people as shown in the Thompson Cortisol Hypothesis. It is likely
that these elevated cortisol levels are also seen in people with MS.
The possible link between EMG in the jaw muscles and rises in saliva
cortisol levels during yawning were investigated in a randomized
controlled trial of 60 volunteers aged 18-69 years who were exposed
to conditions that were designed to elicit the yawning response.
Saliva samples were collected at the start and after yawning, or at the
end of the presentation of yawning-provoking stimuli, in the absence
of a yawn, and EMG data was additionally collected during rest and
yawning phases. Hospital Anxiety and Depression Scale, Yawning
Susceptibility Scale, General Health Questionnaire, demographic,
and health details were collected and the following exclusion criteria
were adopted: chronic fatigue, diabetes, fibromyalgia, heart
condition, high blood pressure, hormone replacement therapy,
multiple sclerosis, and stroke. Significant differences were found
between the saliva cortisol samples for the yawners, t (23) = -4.263, p
= 0.000, as compared with the non-yawners between rest and poststimuli,
which was non-significant. There were also significant
differences between yawners and non-yawners for the EMG
potentials with the yawners having higher rest and post-yawning
potentials. Significant evidence was found to support the Thompson
Cortisol Hypothesis suggesting that rises in cortisol levels are
associated with the yawning response. Further research is underway
to explore the use of cortisol as a potential diagnostic tool as an assist
to the early diagnosis of symptoms related to neurological disorders.
Bournemouth University Research & Ethics approval granted:
JC28/1/13-KA6/9/13. Professional code of conduct, confidentiality,
and safety issues have been addressed and approved in the Ethics
submission. Trials identification number: ISRCTN61942768.
http://www.controlled-trials.com/isrctn/
Abstract: In the present study we have investigated axial
buckling characteristics of nanocomposite beams reinforced by
single-walled carbon nanotubes (SWCNTs). Various types of beam
theories including Euler-Bernoulli beam theory, Timoshenko beam
theory and Reddy beam theory were used to analyze the buckling
behavior of carbon nanotube-reinforced composite beams.
Generalized differential quadrature (GDQ) method was utilized to
discretize the governing differential equations along with four
commonly used boundary conditions. The material properties of the
nanocomposite beams were obtained using molecular dynamic (MD)
simulation corresponding to both short-(10,10) SWCNT and long-
(10,10) SWCNT composites which were embedded by amorphous
polyethylene matrix. Then the results obtained directly from MD
simulations were matched with those calculated by the mixture rule
to extract appropriate values of carbon nanotube efficiency
parameters accounting for the scale-dependent material properties.
The selected numerical results were presented to indicate the
influences of nanotube volume fractions and end supports on the
critical axial buckling loads of nanocomposite beams relevant to
long- and short-nanotube composites.
Abstract: Different countries have introduced different schemes
and policies to counter global warming. The rationale behind the
proposed policies and the potential barriers to successful
implementation of the policies adopted by the countries were
analyzed and estimated based on different models. It is argued that
these models enhance the transparency and provide a better
understanding to the policy makers. However, these models are
underpinned with several structural and baseline assumptions. These
assumptions, modeling features and future prediction of emission
reductions and other implication such as cost and benefits of a
transition to a low-carbon economy and its economy wide impacts
were discussed. On the other hand, there are potential barriers in the
form political, financial, and cultural and many others that pose a
threat to the mitigation options.
Abstract: This paper reports the viability of developing Zn-27Al
alloy matrix hybrid composites reinforced with alumina, graphite and
fly ash (solid waste bye product of coal in thermal power plants).
This research work was aimed at developing low cost-high
performance Zn-27Al matrix composite with low density. Alumina
particulates (Al2O3), graphite added with 0, 2, 3, 4 and 5 wt% fly ash
were utilized to prepare 10wt% reinforcing phase with Zn-27Al alloy
as matrix using two-step stir casting method. Density measurement,
estimated percentage porosity, tensile testing, micro hardness
measurement and optical microscopy were used to assess the
performance of the composites produced. The results show that the
hardness, ultimate tensile strength, and percent elongation of the
hybrid composites decrease with increase in fly ash content. The
maximum decrease in hardness and ultimate tensile strength of
13.72% and 15.25% respectively were observed for composite grade
containing 5wt% fly ash. The percentage elongation of composite
sample without fly ash is 8.9% which is comparable with that of the
sample containing 2wt% fly ash with percentage elongation of 8.8%.
The fracture toughness of the fly ash containing composites was
however superior to those of composites without fly ash with 5wt%
fly ash containing composite exhibiting the highest fracture
toughness. The results show that fly ash can be utilized as
complementary reinforcement in ZA-27 alloy matrix composite to
reduce cost.
Abstract: A repairable mechanical system (as agricultural
tractor) is subject to deterioration or repeated failure and needs a
repair shops and also operator’s capability for the repair and
maintenance operations. Data are based on field visits and interviews
with 48MF 285 tractor operators from 14 villages collected in north
of Khouzestan province. The results showed that most operators were
lack the technical skill to service and repair tractors due to
insufficient training, specific education and work experience.
Inadequate repair and maintenance facilities, such as workshops,
mechanics and spare parts depots cause delays in repair work in the
survey areas. Farmers do not keep accurate service records and most
of them disregard proper maintenance and service of their tractors,
such as changing engine oil without following the manufacturer’s
recommendations. Since, Repair and maintenance facilities should be
established in village areas to guarantee timely repair in case of
breakdowns and to make spare parts available at low price. The
operators should keep service records accurately and adhere to
maintenance and service schedules according to the manufacturer’s
instructions. They should also be encouraged to do the service and
maintain their tractors properly.
Abstract: Second generation military Filipino Amerasians
comprise a formidable contemporary segment of the estimated
250,000-plus biracial Amerasians in the Philippines today. Overall,
they are a stigmatized and socioeconomically marginalized diaspora;
historically, they were abandoned or estranged by U.S. military
personnel fathers assigned during the century-long Colonial, Post-
World War II and Cold War Era of permanent military basing (1898-
1992). Indeed, U.S. military personnel are assigned in smaller
numbers in the Philippines today. This inquiry is an outgrowth of two
recent small sample studies. The first surfaced the impact of the U.S.
military prostitution system on formation of the ‘Derivative
Amerasian Family Construct’ on first generation Amerasians; a
second, qualitative case study suggested the continued effect of the
prostitution systems' destructive impetuous on second generation
Amerasians. The intent of this current qualitative, multiple-case study
was to actively seek out second generation sex industry toilers. The
purpose was to focus further on this human phenomenon in the postbasing
and post-military prostitution system eras. As background, the
former military prostitution apparatus has transformed into a modern
dynamic of rampant sex tourism and prostitution nationwide. This is
characterized by hotel and resorts offering unrestricted carnal access,
urban and provincial brothels (casas), discos, bars and pickup clubs,
massage parlors, local barrio karaoke bars and street prostitution. A
small case study sample (N = 4) of female and male second
generation Amerasians were selected. Sample formation employed a
non-probability ‘snowball’ technique drawing respondents from the
notorious Angeles, Metro Manila, Olongapo City ‘AMO Amerasian
Triangle’ where most former U.S. military installations were sited
and modern sex tourism thrives. A six-month study and analysis of
in-depth interviews of female and male sex laborers, their families
and peers revealed a litany of disturbing, and troublesome
experiences. Results showed profiles of debilitating human poverty,
history of family disorganization, stigmatization, social
marginalization and the ghost of the military prostitution system and
its harmful legacy on Amerasian family units. Emerging were testimonials of wayward young people ensnared in a maelstrom of
deep economic deprivation, familial dysfunction, psychological
desperation and societal indifference. The paper recommends that
more study is needed and implications of unstudied psychosocial and
socioeconomic experiences of distressed younger generations of
military Amerasians require specific research. Heretofore apathetic or
disengaged U.S. institutions need to confront the issue and formulate
activist and solution-oriented social welfare, human services and
immigration easement policies and alternatives. These institutions
specifically include academic and social science research agencies,
corporate foundations, the U.S. Congress, and Departments of State,
Defense and Health and Human Services, and Homeland Security
(i.e. Citizen and Immigration Services) It is them who continue to
endorse a laissez-faire policy of non-involvement over the entire
Filipino Amerasian question. Such apathy, the paper concludes,
relegates this consequential but neglected blood progeny to the status
of humiliating destitution and exploitation. Amerasians; thus, remain
entrapped in their former colonial, and neo-colonial habitat.
Ironically, they are unwitting victims of a U.S. American homeland
that fancies itself geo-politically as a strong and strategic military
treaty ally of the Philippines in the Western Pacific.
Abstract: The influence of cultivation factors such as content of ammonium sulfate, glucose and water in the culture medium and particle size of dry orange waste, on their bioconversion for pectinase production was studied using complete factorial design. A polygalacturonase (PG) was isolated using ion exchange chromatography under gradient elution 0-0,5 m/l NaCl (column equilibrate with acetate buffer pH 4,5), subsequently by sephadex G75 column chromatography was applied and the molecular weight was obtained about 51,28 KDa. Purified PG enzyme exhibits a pH and temperature optima of activity at 5 and 35°C respectively. Treatment of apple juice by purified enzyme extract yielded a clear juice, which was competitive with juice yielded by pure Sigma Aldrich Aspergillus niger enzyme.
Abstract: Cole-Cole parameters of 40 post-menopausal women
are compared with their DEXA bone mineral density measurements.
Impedance characteristics of four extremities are compared; left and
right extremities are statistically same, but lower extremities are
statistically different than upper ones due to their different fat
content. The correlation of Cole-Cole impedance parameters to bone
mineral density (BMD) is observed to be higher for dominant arm.
With the post-menopausal population, ANOVA tests of the dominant
arm characteristic frequency, as a predictor for DEXA classified
osteopenic and osteoporic population around lumbar spine, is
statistically very significant. When used for total lumbar spine
osteoporosis diagnosis, the area under the Receiver Operating Curve
of the characteristic frequency is 0.830, suggesting that the Cole-Cole
plot characteristic frequency could be a useful diagnostic parameter
when integrated into standard screening methods for osteoporosis.
Moreover, the characteristic frequency can be directly measured by
monitoring frequency driven angular behavior of the dominant arm
without performing any complex calculation.
Abstract: Electrostatic interaction energy (ΔEEDL) is a part of the Extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) theory, which, together with van der Waals (ΔEVDW) and acid base (ΔEAB) interaction energies, has been extensively used to investigate the initial adhesion of bacteria to surfaces. Electrostatic or electrical double layer interaction energy is considerably affected by surface potential; however it cannot be determined experimentally and is usually replaced by zeta (ζ) potential via electrophoretic mobility. This paper focusses on the effect of ionic concentration as a function of pH and the effect of mineral grain size on ζ potential. It was found that both ionic strength and mineral grain size play a major role in determining the value of ζ potential for the adhesion of P. putida to hematite and quartz surfaces. Higher ζ potential values lead to higher electrostatic interaction energies and eventually to higher total XDLVO interaction energy resulting in bacterial repulsion.
Abstract: In this paper, relationship between different properties
of IC concrete and water cement ratio, obtained from a
comprehensive experiment conducted on IC using local materials
(Burnt clay chips- BC) is presented. In addition, saturated SAP was
used as an IC material in some cases. Relationships have been
developed through regression analysis. The focus of this analysis is
on developing relationship between a dependent variable and an
independent variable. Different percent replacements of BC and
water cement ratios were used. Compressive strength, modulus of
elasticity, water permeability and chloride permeability were tested
and variations of these parameters were analyzed with respect to
water cement ratio.
Abstract: Photovoltaic (PV) power generation systems, mainly
small scale, are rapidly being deployed in Jordan. The impact of these
systems on the grid has not been studied or analyzed. These systems
can cause many technical problems such as reverse power flows and
voltage rises in distribution feeders, and real and reactive power
transients that affect the operation of the transmission system. To
fully understand and address these problems, extensive research,
simulation, and case studies are required. To this end, this paper
studies the cloud shadow effect on the power generation of a ground
mounted PV system installed at the test field of the Renewable
Energy Center at the Applied Science University.
Abstract: This study presents three different approaches to
estimate bubble point pressures for the binary system of CO2 and
ethyl palmitate fatty acid ethyl ester. The first method involves the
Peng-Robinson (PR) Equation of State (EoS) with the conventional
mixing rule of Van der Waals. The second approach involves the PR
EOS together with the Wong Sandler (WS) mixing rule, coupled with
the UNIQUAC GE model. In order to model the bubble point
pressures with this approach, the volume and area parameter for ethyl
palmitate were estimated by the Hansen group contribution method.
The last method involved the Peng-Robinson, combined with the
Wong-Sandler method, but using NRTL as the GE model. Results
using the Van der Waals mixing rule clearly indicated that this
method has the largest errors among all three methods, with errors in
the range of 3.96-6.22%. The PR-WS-UNIQUAC method exhibited
small errors, with average absolute deviations between 0.95 to 1.97
percent. The PR-WS-NRTL method led to the least errors, where
average absolute deviations ranged between 0.65-1.7%.
Abstract: One of the most critical decision points in the design of a
face recognition system is the choice of an appropriate face representation.
Effective feature descriptors are expected to convey sufficient, invariant
and non-redundant facial information. In this work we propose a set of
Hahn moments as a new approach for feature description. Hahn moments
have been widely used in image analysis due to their invariance, nonredundancy
and the ability to extract features either globally and locally.
To assess the applicability of Hahn moments to Face Recognition we
conduct two experiments on the Olivetti Research Laboratory (ORL)
database and University of Notre-Dame (UND) X1 biometric collection.
Fusion of the global features along with the features from local facial
regions are used as an input for the conventional k-NN classifier. The
method reaches an accuracy of 93% of correctly recognized subjects for
the ORL database and 94% for the UND database.