Abstract: Identifying the nature of protein-nanoparticle
interactions and favored binding sites is an important issue in
functional characterization of biomolecules and their physiological
responses. Herein, interaction of silver nanoparticles with lysozyme
as a model protein has been monitored via fluorescence spectroscopy.
Formation of complex between the biomolecule and silver
nanoparticles (AgNPs) induced a steady state reduction in the
fluorescence intensity of protein at different concentrations of
nanoparticles. Tryptophan fluorescence quenching spectra suggested
that silver nanoparticles act as a foreign quencher, approaching the
protein via this residue. Analysis of the Stern-Volmer plot showed
quenching constant of 3.73 μM−1. Moreover, a single binding site in
lysozyme is suggested to play role during interaction with AgNPs,
having low affinity of binding compared to gold nanoparticles.
Unfolding studies of lysozyme showed that complex of lysozyme-
AgNPs has not undergone structural perturbations compared to the
bare protein. Results of this effort will pave the way for utilization of
sensitive spectroscopic techniques for rational design of
nanobiomaterials in biomedical applications.
Abstract: The application of a high frequency signal injection method as speed and position observer in PMSM drives has been a research focus. At present, the precision of this method is nearly good as that of ten-bit encoder. But there are some questions for estimating position polarity. Based on high frequency signal injection, this paper presents a method to compensate position polarity for permanent magnet synchronous motor (PMSM). Experiments were performed to test the effectiveness of the proposed algorithm and results present the good performance.
Abstract: Reservoirs with high pressures and temperatures
(HPHT) that were considered to be atypical in the past are now
frequent targets for exploration. For downhole oilfield drilling tools
and components, the temperature and pressure affect the mechanical
strength. To address this issue, a finite element analysis (FEA) for
206.84 MPa (30 ksi) pressure and 165°C has been performed on the
pressure housing of the measurement-while-drilling/logging-whiledrilling
(MWD/LWD) density tool.
The density tool is a MWD/LWD sensor that measures the density
of the formation. One of the components of the density tool is the
pressure housing that is positioned in the tool. The FEA results are
compared with the experimental test performed on the pressure
housing of the density tool. Past results show a close match between
the numerical results and the experimental test. This FEA model can
be used for extreme HPHT and ultra HPHT analyses, and/or optimal
design changes.
Abstract: In today's complex global environment, emotional intelligence in educational administrations encompasses self-regard that is formed to utilize communication effectiveness. The paper is undertaken to understand the relationship between managers- emotional intelligence especially self-regard and employees to improve communication effectiveness in educational administrations of Iran. Data (N = 145) for this study were collected through questionnaires that participants were managers and employees educational administrations of Iran. The aim of this paper assess the emotional intelligence especially self-regard of managers and employees and its relationship with communication effectiveness in educational administrations of Iran. This paper explained self-regard that has a high relationship with communication especially communication effectiveness. Self-regard plays an important role in communication effectiveness. Individuals with high self-regard tend to have higher emotional intelligence and this action lead to improve communication effectiveness. The result of the paper shows a strong correspondence between self-regard and communication effectiveness in educational administrations.
Abstract: The main aim of the current study was to examine the
effect of emotional intelligence on retention. The study also aimed at
analyzing the role of job involvement, as a moderator, in the effect of
emotional intelligence on retention. Using data gathered from 241
employees working with hotels and tourism corporations listed in
Amman Stock Exchange in Jordan, emotional intelligence, job
involvement and retention were measured. Hierarchical regression
analyses were used to test the three main hypotheses. Results
indicated that retention was related to emotional intelligence.
Moreover, the study yielded support for the claim that job
involvement had a moderating effect on the relationship between
emotional intelligence and retention.
Abstract: Chlorine is one of the most abundant elements in
nature, which undergoes a complex biogeochemical cycle. Chlorine
bound in some substances is partly responsible for atmospheric ozone
depletion and contamination of some ecosystems. As due to
international regulations anthropogenic burden of volatile
organochlorines (VOCls) in atmosphere decreases, natural sources
(plants, soil, abiotic formation) are expected to dominate VOCl
production in the near future. Examples of plant VOCl production are
methyl chloride, and bromide emission from (sub)tropical ferns,
chloroform, 1,1,1-trichloroethane and tetrachloromethane emission
from temperate forest fern and moss. Temperate forests are found to
emit in addition to the previous compounds tetrachloroethene, and
brominated volatile compounds. VOCls can be taken up and further
metabolized in plants. The aim of this work is to identify and
quantitatively analyze the formed VOCls in temperate forest
ecosystems by a cryofocusing/GC-ECD detection method, hence
filling a gap of knowledge in the biogeochemical cycle of chlorine.
Abstract: The one-class support vector machine “support vector
data description” (SVDD) is an ideal approach for anomaly or outlier
detection. However, for the applicability of SVDD in real-world
applications, the ease of use is crucial. The results of SVDD are
massively determined by the choice of the regularisation parameter C
and the kernel parameter of the widely used RBF kernel. While for
two-class SVMs the parameters can be tuned using cross-validation
based on the confusion matrix, for a one-class SVM this is not
possible, because only true positives and false negatives can occur
during training. This paper proposes an approach to find the optimal
set of parameters for SVDD solely based on a training set from
one class and without any user parameterisation. Results on artificial
and real data sets are presented, underpinning the usefulness of the
approach.
Abstract: In this paper, the details of an experimental method to measure the clamping force value at bolted connections due to application of wrenching torque to tighten the nut have been presented. A simplified bolted joint including a holed plate with a single bolt was considered to carry out the experiments. This method was designed based on Hooke-s law by measuring compressive axial strain of a steel bush placed between the nut and the plate. In the experimental procedure, the values of clamping force were calculated for seven different levels of applied torque, and this process was repeated three times for each level of the torque. Moreover, the effect of lubrication of threads on the clamping value was studied using the same method. In both conditions (dry and lubricated threads), relation between the torque and the clamping force have been displayed in graphs.
Abstract: Bovine viral diarrhea virus (BVDV) can cause lifelong
persistent infection. One reason for the phenomena is attributed to
BVDV infection to placenta tissue. However the mechanisms that
BVDV invades into placenta tissue remain unclear. To clarify the
molecular mechanisms, we investigated the possible means that
BVDV entered into bovine trophoblast cells (TPC). Yeast two-hybrid
system was used to identify proteins extracted from TPC, which
interact with BVDV envelope glycoprotein E2. A PGbkt7-E2 yeast
expression vector and TPC cDNA library were constructed. Through
two rounds of screening, three positive clones were identified.
Sequencing analysis indicated that all the three positive clones
encoded the same protein clathrin. Physical interaction between
clathrin and BVDV E2 protein was further confirmed by
coimmunoprecipitation experiments. This result suggested that the
clathrin might play a critical role in the process of BVDV entry into
placenta tissue and might be a novel antiviral target for preventing
BVDV infection.
Abstract: The objective of this paper was to designing a
ventilation system to enhance the performance of roof solar collector
(RSC) for reducing heat accumulation inside the house. The RSC has
1.8 m2 surface area made of CPAC monier roof tiles on the upper part
and gypsum board on the lower part. The space between CPAC
monier and gypsum board was fixed at 14 cm.
Ventilation system of modified roof solar collector (modified
RSC) consists of 9 tubes of 0.15m diameter and installed in the
lower part of RSC. Experimental result showed that the temperature
of the room, and attic temperature. The average temperature
reduction of room of house used modified RSC is about 2oC. and the
percentage of room temperature reduction varied between 0 to 10%.
Therefore, modified RSC is an interesting option in the sense that it
promotes solar energy and conserve energy.
Abstract: The main objective of this paper is to contribute the
existing knowledge transfer and IT Outsourcing literature
specifically in the context of Malaysia by reviewing the current
practices of e-government IT outsourcing in Malaysia including the
issues and challenges faced by the public agencies in transferring the
knowledge during the engagement. This paper discusses various
factors and different theoretical model of knowledge transfer starting
from the traditional model to the recent model suggested by the
scholars. The present paper attempts to align organizational
knowledge from the knowledge-based view (KBV) and
organizational learning (OL) lens. This review could help shape the
direction of both future theoretical and empirical studies on inter-firm
knowledge transfer specifically on how KBV and OL perspectives
could play significant role in explaining the complex relationships
between the client and vendor in inter-firm knowledge transfer and
the role of organizational management information system and
Transactive Memory System (TMS) to facilitate the organizational
knowledge transferring process. Conclusion is drawn and further
research is suggested.
Abstract: Long term rainfall analysis and prediction is a
challenging task especially in the modern world where the impact of
global warming is creating complications in environmental issues.
These factors which are data intensive require high performance
computational modeling for accurate prediction. This research paper
describes a prototype which is designed and developed on grid
environment using a number of coupled software infrastructural
building blocks. This grid enabled system provides the demanding
computational power, efficiency, resources, user-friendly interface,
secured job submission and high throughput. The results obtained
using sequential execution and grid enabled execution shows that
computational performance has enhanced among 36% to 75%, for
decade of climate parameters. Large variation in performance can be
attributed to varying degree of computational resources available for
job execution.
Grid Computing enables the dynamic runtime selection, sharing
and aggregation of distributed and autonomous resources which plays
an important role not only in business, but also in scientific
implications and social surroundings. This research paper attempts to
explore the grid enabled computing capabilities on weather indices
from HOAPS data for climate impact modeling and change
detection.
Abstract: This paper is to investigate the impplementation of security
mechanism in object oriented database system. Formal methods
plays an essential role in computer security due to its powerful expressiveness
and concise syntax and semantics. In this paper, both issues
of specification and implementation in database security environment
will be considered; and the database security is achieved through
the development of an efficient implementation of the specification
without compromising its originality and expressiveness.
Abstract: This article provides empirical evidence on the effect
of domestic and international factors on the U.S. current account
deficit. Linear dynamic regression and vector autoregression models
are employed to estimate the relationships during the period from 1986
to 2011. The findings of this study suggest that the current and lagged
private saving rate and foreign current account for East Asian
economies have played a vital role in affecting the U.S. current
account. Additionally, using Granger causality tests and variance
decompositions, the change of the productivity growth and foreign
domestic demand are determined to influence significantly the change
of the U.S. current account. To summarize, the empirical relationship
between the U.S. current account deficit and its determinants is
sensitive to alternative regression models and specifications.
Abstract: The present study was designed to investigate the
cardio protective role of chronic oral administration of alcoholic
extract of Terminalia arjuna in in-vivo ischemic reperfusion injury
and the induction of HSP72. Rabbits, divided into three groups, and
were administered with the alcoholic extract of the bark powder of
Terminalia arjuna (TAAE) by oral gavage [6.75mg/kg: (T1) and
9.75mg/kg: (T2), 6 days /week for 12 weeks]. In open-chest
Ketamine pentobarbitone anaesthetized rabbits, the left anterior
descending coronary artery was occluded for 15 min of ischemia
followed by 60 min of reperfusion. In the vehicle-treated group,
ischemic-reperfusion injury (IRI) was evidenced by depression of
global hemodynamic function (MAP, HR, LVEDP, peak LV (+) & (-
) (dP/dt) along with depletion of HEP compounds. Oxidative stress
in IRI was evidenced by, raised levels of myocardial TBARS and
depletion of endogenous myocardial antioxidants GSH, SOD and
catalase. Western blot analysis showed a single band corresponding
to 72 kDa in homogenates of hearts from rabbits treated with both the
doses. In the alcoholic extract of the bark powder of Terminalia
arjuna treatment groups, both the doses had better recovery of
myocardial hemodynamic function, with significant reduction in
TBARS, and rise in SOD, GSH, catalase were observed. The results
of the present study suggest that the alcoholic extract of the bark
powder of Terminalia arjuna in rabbit induces myocardial HSP 72
and augments myocardial endogenous antioxidants, without causing
any cellular injury and offered better cardioprotection against
oxidative stress associated with myocardial IR injury.
Abstract: We investigated oxidative DNA damage caused by
radio frequency radiation using 8-oxo-7, 8-dihydro-2'-
deoxyguanosine (8-oxodG) generated in mice tissues after exposure
to 900 MHz mobile phone radio frequency in three independent
experiments. The RF was generated by a Global System for Mobile
Communication (GSM) signal generator. The radio frequency field
was adjusted to 25 V/m. The whole body specific absorption rate
(SAR) was 1.0 W/kg. Animals were exposed to this field for 30 min
daily for 30 days. 24 h post-exposure, blood serum, brain and spleen
were removed and DNA was isolated. Enzyme-linked
immunosorbent assay (ELISA) was used to measure 8-oxodG
concentration. All animals survived the whole experimental period.
The body weight of animals did not change significantly at the end of
the experiment. No statistically significant differences observed in
the levels of oxidative stress. Our results are not in favor of the
hypothesis that 900 MHz RF induces oxidative damage.
Abstract: Researchers have been applying tional intelligence (AI/CI) methods to computer games. In this research field, further researchesare required to compare AI/CI
methods with respect to each game application. In th
our experimental result on the comparison of three evolutionary algorithms – evolution strategy, genetic algorithm, and their hybrid
applied to evolving controller agents for the CIG 2007 Simulated Car Racing competition. Our experimental result shows that, premature
convergence of solutions was observed in the case of ES, and GA outperformed ES in the last half of generations. Besides, a hybrid
which uses GA first and ES next evolved the best solution among the whole solutions being generated. This result shows the ability of GA in
globally searching promising areas in the early stage and the ability of ES in locally searching the focused area (fine-tuning solutions).
Abstract: It well recognized that one feature that makes a
successful company is its ability to successfully align its business goals with its information communication technologies platform.
Enterprise Resource Planning (ERP) systems contribute to achieve better performance by integrating various business functions and
providing support for information flows. However, the technological
systems complexity is known to prevent the business users to exploit in an efficient way the Enterprise Resource Planning Systems (ERP).
This paper aims to investigate the role of training in improving the
usage of ERP systems. To this end, we have designed an instrument
survey to employees of a Norwegian multinational global provider of
technology solutions. Based on the analysis of collected data, we have delineated a training model that could be high relevance for
both researchers and practitioners as a step towards a better
understanding of ERP system implementation.
Abstract: The aim of this study was to compare the solubility of selected volatile organic compounds in water and silicon oil using the simple static headspace method. The experimental design allowed equilibrium achievement within 30 – 60 minutes. Infinite dilution activity coefficients and Henry-s law constants for various organics representing esters, ketones, alkanes, aromatics, cycloalkanes and amines were measured at 303K. The measurements were reproducible with a relative standard deviation and coefficient of variation of 1.3x10-3 and 1.3 respectively. The static determined activity coefficients using shaker flasks were reasonably comparable to those obtained using the gas liquid - chromatographic technique and those predicted using the group contribution methods mainly the UNIFAC. Silicon oil chemically known as polydimethysiloxane was found to be better absorbent for VOCs than water which quickly becomes saturated. For example the infinite dilution mole fraction based activity coefficients of hexane is 0.503 and 277 000 in silicon oil and water respectively. Thus silicon oil gives a superior factor of 550 696. Henry-s law constants and activity coefficients at infinite dilution play a significant role in the design of scrubbers for abatement of volatile organic compounds from contaminated air streams. This paper presents the phase equilibrium of volatile organic compounds in very dilute aqueous and polymeric solutions indicating the movement and fate of chemical in air and solvent. The successful comparison of the results obtained here and those obtained using other methods by the same authors and in literature, means that the results obtained here are reliable.
Abstract: Despite the recent surge of research in control of
worm propagation, currently, there is no effective defense system
against such cyber attacks. We first design a distributed detection
architecture called Detection via Distributed Blackholes (DDBH).
Our novel detection mechanism could be implemented via virtual
honeypots or honeynets. Simulation results show that a worm can be
detected with virtual honeypots on only 3% of the nodes. Moreover,
the worm is detected when less than 1.5% of the nodes are infected.
We then develop two control strategies: (1) optimal dynamic trafficblocking,
for which we determine the condition that guarantees
minimum number of removed nodes when the worm is contained and
(2) predictive dynamic traffic-blocking–a realistic deployment of
the optimal strategy on scale-free graphs. The predictive dynamic
traffic-blocking, coupled with the DDBH, ensures that more than
40% of the network is unaffected by the propagation at the time
when the worm is contained.