Abstract: This paper compares the findings of two studies conducted to determine the effectiveness of simulation-based, hands-on and feedback mechanism on students learning by answering the following questions: 1). Does the use of simulation improve students’ learning outcomes? 2). How do students perceive the instructional design features embedded in the simulation program such as exploration and scaffolding support in learning new concepts? 3.) What is the effect of feedback mechanisms on students’ learning in the use of simulation-based labs? The paper also discusses the other aspects of findings which reveal that simulation by itself is not very effective in promoting student learning. Simulation becomes effective when it is followed by hands-on activity and feedback mechanisms. Furthermore, the paper presents recommendations for improving student learning through the use of simulation-based, hands-on, and feedback-based teaching methodologies.
Abstract: Introduction: This work is aimed to represent the use of the OPTI-JET CS MD1 MR prototype for application of neutral electrolyzed oxidizing water (NEOW) in magnetic resonance rooms. Material and Methods: We produced and used OPTI-JET CS MD1 MR aerosolisator whereby was performed aerosolization. The presence of microorganisms before and after the aerosolisation was recorded with the help of cyclone air sampling. Colony formed units (CFU) was counted. Results: The number of microorganisms in magnetic resonance 3T room was low as expected. Nevertheless, a possible CFU reduction of 87% was recorded. Conclusions: The research has shown that the use of EOW for the air and hard surface disinfection can considerably reduce the presence of microorganisms and consequently the possibility of hospital infections. It has also demonstrated that the use of OPTI-JET CS MD1 MR is very good. With this research, we started new guidelines for aerosolization in magnetic resonance rooms. Future work: We predict that presented technique works very good but we must focus also on time capacity sensors, and new appropriate toxicological studies.
Abstract: Water suspensions of in-organic (metals and oxides)
and organic nano-objects (chitozan and collagen) were subjected to
the treatment of direct and alternative electrical fields. In addition to
quasi-periodical spatial patterning resonance-like performance of
spatial distributions of these suspensions has been found at low
frequencies of alternating electrical field. These resonances are
explained as the result of creation of equilibrium states of groups of
charged nano-objects with opposite signs of charges at the interparticle
distances where the forces of Coulomb attraction are
compensated by the repulsion forces induced by relatively negative
polarization of hydrated regions surrounding the nanoparticles with
respect to pure water. The low frequencies of these resonances are
explained by comparatively big distances between the particles and
their big masses with t\respect to masses of atoms constituting
molecules with high resonance frequencies. These new resonances
open a new approach to detailed modeling and understanding of
mechanisms of the influence of electrical fields on the functioning of
internal organs of living organisms at the level of cells and neurons.
Abstract: MicroRNAs are small non-coding RNA found in
many different species. They play crucial roles in cancer such as
biological processes of apoptosis and proliferation. The identification
of microRNA-target genes can be an essential first step towards to
reveal the role of microRNA in various cancer types. In this paper,
we predict miRNA-target genes for lung cancer by integrating
prediction scores from miRanda and PITA algorithms used as a
feature vector of miRNA-target interaction. Then, machine-learning
algorithms were implemented for making a final prediction. The
approach developed in this study should be of value for future studies
into understanding the role of miRNAs in molecular mechanisms
enabling lung cancer formation.
Abstract: Social networks have recently gained a growing
interest on the web. Traditional formalisms for representing social
networks are static and suffer from the lack of semantics. In this
paper, we will show how semantic web technologies can be used to
model social data. The SemTemp ontology aligns and extends
existing ontologies such as FOAF, SIOC, SKOS and OWL-Time to
provide a temporal and semantically rich description of social data.
We also present a modeling scenario to illustrate how our ontology
can be used to model social networks.
Abstract: The effectiveness of microchannels in enhancing heat
transfer has been demonstrated in the semiconductor industry. In
order to tap the microscale heat transfer effects into macro
geometries, overcoming the cost and technological constraints,
microscale passages were created in macro geometries machined
using conventional fabrication methods. A cylindrical insert was
placed within a pipe, and geometrical profiles were created on the
outer surface of the insert to enhance heat transfer under steady-state
single-phase liquid flow conditions. However, while heat transfer
coefficient values of above 10 kW/m2·K were achieved, the heat
transfer enhancement was accompanied by undesirable pressure drop
increment. Therefore, this study aims to address the high pressure
drop issue using Constructal theory, a universal design law for both
animate and inanimate systems. Two designs based on Constructal theory were developed to study
the effectiveness of Constructal features in reducing the pressure drop
increment as compared to parallel channels, which are commonly
found in microchannel fabrication. The hydrodynamic and heat
transfer performance for the Tree insert and Constructal fin (Cfin)
insert were studied using experimental methods, and the underlying
mechanisms were substantiated by numerical results. In technical
terms, the objective is to achieve at least comparable increment in
both heat transfer coefficient and pressure drop, if not higher
increment in the former parameter. Results show that the Tree insert improved the heat transfer
performance by more than 16 percent at low flow rates, as compared
to the Tree-parallel insert. However, the heat transfer enhancement
reduced to less than 5 percent at high Reynolds numbers. On the
other hand, the pressure drop increment stayed almost constant at 20
percent. This suggests that the Tree insert has better heat transfer
performance in the low Reynolds number region. More importantly,
the Cfin insert displayed improved heat transfer performance along
with favourable hydrodynamic performance, as compared to Cfinparallel
insert, at all flow rates in this study. At 2 L/min, the
enhancement of heat transfer was more than 30 percent, with 20
percent pressure drop increment, as compared to Cfin-parallel insert.
Furthermore, comparable increment in both heat transfer coefficient
and pressure drop was observed at 8 L/min. In other words, the Cfin
insert successfully achieved the objective of this study. Analysis of the results suggests that bifurcation of flows is
effective in reducing the increment in pressure drop relative to heat
transfer enhancement. Optimising the geometries of the Constructal
fins is therefore the potential future study in achieving a bigger stride
in energy efficiency at much lower costs.
Abstract: The exploitation of flow pulsation in micro- and
mini-channels is a potentially useful technique for enhancing cooling
of high-end photonics and electronics systems. It is thought that
pulsation alters the thickness of the hydrodynamic and thermal
boundary layers, and hence affects the overall thermal resistance
of the heat sink. Although the fluid mechanics and heat transfer
are inextricably linked, it can be useful to decouple the parameters
to better understand the mechanisms underlying any heat transfer
enhancement. Using two-dimensional, two-component particle image
velocimetry, the current work intends to characterize the heat transfer
mechanisms in pulsating flow with a mean Reynolds number of
48 by experimentally quantifying the hydrodynamics of a generic
liquid-cooled channel geometry. Flows circulated through the test
section by a gear pump are modulated using a controller to achieve
sinusoidal flow pulsations with Womersley numbers of 7.45 and
2.36 and an amplitude ratio of 0.75. It is found that the transient
characteristics of the measured velocity profiles are dependent on the
speed of oscillation, in accordance with the analytical solution for
flow in a rectangular channel. A large velocity overshoot is observed
close to the wall at high frequencies, resulting from the interaction
of near-wall viscous stresses and inertial effects of the main fluid
body. The steep velocity gradients at the wall are indicative of
augmented heat transfer, although the local flow reversal may reduce
the upstream temperature difference in heat transfer applications.
While unsteady effects remain evident at the lower frequency, the
annular effect subsides and retreats from the wall. The shear rate at
the wall is increased during the accelerating half-cycle and decreased
during deceleration compared to steady flow, suggesting that the flow
may experience both enhanced and diminished heat transfer during
a single period. Hence, the thickness of the hydrodynamic boundary
layer is reduced for positively moving flow during one half of the
pulsation cycle at the investigated frequencies. It is expected that the
size of the thermal boundary layer is similarly reduced during the
cycle, leading to intervals of heat transfer enhancement.
Abstract: A composite material with carbon fiber and polymer
matrix has been used as adherent for manufacturing adhesive joints.
In order to evaluate different fiber orientations on joint performance,
the adherents with the 0°, ±15°, ±30°, ±45° fiber orientations were
used in the single lap joint configuration. The joints with an overlap
length of 25 mm were prepared according to the ASTM 1002
specifications and subjected to tensile loadings. The structural
adhesive used was a two-part epoxy to be cured at 70°C for an hour.
First, mechanical behaviors of the adherents were measured using
three point bending test. In the test, considerations were given to
stress to failure and elastic modulus. The results were compared with
theoretical ones using rule of mixture. Then, the joints were
manufactured in a specially prepared jig, after a proper surface
preparation. Experimental results showed that the fiber orientations
of the adherents affected the joint performance considerably; the
joints with ±45° adherents experienced the worst shear strength, half
of those with 0° adherents, and in general, there was a great
relationship between the fiber orientations and failure mechanisms.
Delamination problems were observed for many joints, which were
thought to be due to peel effects at the ends of the overlap. It was
proved that the surface preparation applied to the adherent surface
was adequate. For further explanation of the results, a numerical
work should be carried out using a possible non-linear analysis.
Abstract: While the feature sizes of recent Complementary Metal
Oxid Semiconductor (CMOS) devices decrease the influence of static
power prevails their energy consumption. Thus, power savings that
benefit from Dynamic Frequency and Voltage Scaling (DVFS) are
diminishing and temporal shutdown of cores or other microchip
components become more worthwhile. A consequence of powering off unused parts of a chip is that the
relative difference between idle and fully loaded power consumption
is increased. That means, future chips and whole server systems gain
more power saving potential through power-aware load balancing,
whereas in former times this power saving approach had only
limited effect, and thus, was not widely adopted. While powering
off complete servers was used to save energy, it will be superfluous
in many cases when cores can be powered down. An important
advantage that comes with that is a largely reduced time to respond
to increased computational demand. We include the above developments in a server power model
and quantify the advantage. Our conclusion is that strategies from
datacenters when to power off server systems might be used in the
future on core level, while load balancing mechanisms previously
used at core level might be used in the future at server level.
Abstract: Discussing the nexus between global health policy and local practices, this article addresses the recent Ebola outbreak as a role model for narrative co-constructions of epidemic risk. We will demonstrate in how far a theory-driven and methodologically rooted analysis of narrativity can help to improve mechanisms of prevention and intervention whenever epidemic risk needs to be addressed locally in order to contribute to global health. Analyzing the narrative transformation of Ebola, we will also address issues of transcultural problem-solving and of normative questions at stake. In this regard, we seek to contribute to a better understanding of a key question of global health and justice as well as to the underlying ethical questions. By highlighting and analyzing the functions of narratives, this paper provides a translational approach to refine our practices by which we address epidemic risk, be it on the national, the transnational or the global scale.
Abstract: Landfill leachates contain a number of persistent pollutants, including heavy metals. They have the ability to spread in ecosystems and accumulate in fish which most of them are classified as top-consumers of trophic chains. Fish are freely swimming organisms; but perhaps, due to their species-specific ecological and behavioral properties, they often prefer the most suitable biotopes and therefore, did not avoid harmful substances or environments. That is why it is necessary to evaluate the persistent pollutant dispersion in hydroecosystem using fish tissue metal concentration. In hydroecosystems of hybrid type (e.g. river-pond-river) the distance from the pollution source could be a perfect indicator of such a kind of metal distribution. The studies were carried out in the Kairiai landfill neighboring hybrid-type ecosystem which is located 5 km east of the Šiauliai City. Fish tissue (gills, liver, and muscle) metal concentration measurements were performed on two types of ecologically-different fishes according to their feeding characteristics: benthophagous (Gibel carp, roach) and predatory (Northern pike, perch). A number of mathematical models (linear, non-linear, using log and other transformations) have been applied in order to identify the most satisfactorily description of the interdependence between fish tissue metal concentration and the distance from the pollution source. However, the only one log-multiple regression model revealed the pattern that the distance from the pollution source is closely and positively correlated with metal concentration in all predatory fish tissues studied (gills, liver, and muscle).
Abstract: Landfill waste is a common problem as it has an
economic and environmental impact even if it is closed. Landfill
waste contains a high density of various persistent compounds such
as heavy metals, organic and inorganic materials. As persistent
compounds are slowly-degradable or even non-degradable in the
environment, they often produce sublethal or even lethal effects on
aquatic organisms. The aims of the present study were to estimate
sublethal effects of the Kairiai landfill (WGS: 55°55‘46.74“,
23°23‘28.4“) leachate on the locomotor activity of rainbow trout
Oncorhynchus mykiss juveniles using the original system package
developed in our laboratory for automated monitoring, recording and
analysis of aquatic organisms’ activity, and to determine patterns of
fish behavioral response to sublethal effects of leachate. Four
different concentrations of leachate were chosen: 0.125; 0.25; 0.5 and
1.0 mL/L (0.0025; 0.005; 0.01 and 0.002 as part of 96-hour LC50,
respectively). Locomotor activity was measured after 5, 10 and 30
minutes of exposure during 1-minute test-periods of each fish (7 fish
per treatment). The threshold-effect-concentration amounted to 0.18
mL/L (0.0036 parts of 96-hour LC50). This concentration was found
to be even 2.8-fold lower than the concentration generally assumed to
be “safe” for fish. At higher concentrations, the landfill leachate
solution elicited behavioral response of test fish to sublethal levels of
pollutants. The ability of the rainbow trout to detect and avoid
contaminants occurred after 5 minutes of exposure. The intensity of
locomotor activity reached a peak within 10 minutes, evidently
decreasing after 30 minutes. This could be explained by the
physiological and biochemical adaptation of fish to altered
environmental conditions. It has been established that the locomotor
activity of juvenile trout depends on leachate concentration and
exposure duration. Modeling of these parameters showed that the
activity of juveniles increased at higher leachate concentrations, but
slightly decreased with the increasing exposure duration. Experiment
results confirm that the behavior of rainbow trout juveniles is a
sensitive and rapid biomarker that can be used in combination with
the system for fish behavior monitoring, registration and analysis to
determine sublethal concentrations of pollutants in ambient water.
Further research should be focused on software improvement aimed
to include more parameters of aquatic organisms’ behavior and to
investigate the most rapid and appropriate behavioral responses in
different species. In practice, this study could be the basis for the
development and creation of biological early-warning systems
(BEWS).
Abstract: The beginning of 21st century has witnessed new
advancements in the design and use of new materials for biosensing
applications, from nano to macro, protein to tissue. Traditional
analytical methods lack a complete toolset to describe the
complexities introduced by living systems, pathological relations,
discrete hierarchical materials, cross-phase interactions, and
structure-property dependencies. Materiomics – via systematic
molecular dynamics (MD) simulation – can provide structureprocess-
property relations by using a materials science approach
linking mechanisms across scales and enables oriented biosensor
design. With this approach, DNA biosensors can be utilized to detect
disease biomarkers present in individuals’ breath such as acetone for
diabetes. Our wireless sensor array based on single-stranded DNA
(ssDNA)-decorated single-walled carbon nanotubes (SWNT) has
successfully detected trace amount of various chemicals in vapor
differentiated by pattern recognition. Here, we present how MD
simulation can revolutionize the way of design and screening of DNA
aptamers for targeting biomarkers related to oral diseases and oral
health monitoring. It demonstrates great potential to be utilized to
build a library of DNDA sequences for reliable detection of several
biomarkers of one specific disease, and as well provides a new
methodology of creating, designing, and applying of biosensors.
Abstract: Prior literature in the field of adaptive and
personalized learning sequence in e-learning have proposed and
implemented various mechanisms to improve the learning process
such as individualization and personalization, but complex to
implement due to expensive algorithmic programming and need of
extensive and prior data. The main objective of personalizing
learning sequence is to maximize learning by dynamically selecting
the closest teaching operation in order to achieve the learning
competency of learner. In this paper, a revolutionary technique has
been proposed and tested to perform individualization and
personalization using modified reversed roulette wheel selection
algorithm that runs at O(n). The technique is simpler to implement
and is algorithmically less expensive compared to other revolutionary
algorithms since it collects the dynamic real time performance matrix
such as examinations, reviews, and study to form the RWSA single
numerical fitness value. Results show that the implemented system is
capable of recommending new learning sequences that lessens time
of study based on student's prior knowledge and real performance
matrix.
Abstract: The study of implicature which is one of the
discussions of pragmatics is such an interesting and challenging topic
to discuss. Implicature is such a meaning which is implied in such an
utterance which is not the same as its literal meaning. The rapid
development of information technology results social networks as
media to broadcast messages. The broadcast messages may be in the
form of jokes which contain implicature. The research applies the
pragmatic equivalent method to analyze the topics of jokes based on
the implicatures contained in them. Furthermore, the method is also
applied to reveal the purpose of creating implicature in jokes. The
findings include the kinds of implicature found in jokes which are
classified into conventional implicature and conversational
implicature. Then, in detailed analysis, implicature in jokes is divided
into implicature related to gender, culture, and social phenomena.
Furthermore, implicature in jokes may not only be used to give
entertainment but also to soften criticisms or satire so that it does not
sound rude and harsh.
Abstract: Strong anthropogenic impact has uncontrolled
consequences on the nature of the soil. Hence, up-to-date sustainable
methods of soil state improvement are essential. Investigators provide
the evidence that biochar can positively effects physical, chemical,
and biological soil properties and the abundance of mycorrhizal fungi
which are in the focus of this study. The main aim of the present
investigation is to demonstrate the effect of two types of plant growth
promoting bacteria (PGPB) inoculums along with the beech wood
biochar and mineral N additives on mycorrhizal colonization.
Experiment has been set up in laboratory conditions with containers
filled with arable soil from the protection zone of the main water
source “Brezova nad Svitavou”. Lactuca sativa (lettuce) has been
selected as a model plant. Based on the obtained data, it can be
concluded that mycorrhizal colonization increased as the result of
combined influence of biochar and PGPB inoculums amendment. In
addition, correlation analyses showed that the numbers of main
groups of cultivated bacteria were dependent on the degree of
mycorrhizal colonization.
Abstract: One of the global combinatorial optimization
problems in machine learning is feature selection. It concerned with
removing the irrelevant, noisy, and redundant data, along with
keeping the original meaning of the original data. Attribute reduction
in rough set theory is an important feature selection method. Since
attribute reduction is an NP-hard problem, it is necessary to
investigate fast and effective approximate algorithms. In this paper,
we proposed two feature selection mechanisms based on memetic
algorithms (MAs) which combine the genetic algorithm with a fuzzy
record to record travel algorithm and a fuzzy controlled great deluge
algorithm, to identify a good balance between local search and
genetic search. In order to verify the proposed approaches, numerical
experiments are carried out on thirteen datasets. The results show that
the MAs approaches are efficient in solving attribute reduction
problems when compared with other meta-heuristic approaches.
Abstract: Prosecution of sexual violence in international
criminal law requires not only an understanding of the mechanisms
employed to prosecute sexual violence but also a critical analysis of
the factors facilitating perpetuation of such crimes in armed conflicts.
The extrapolations laid out in this essay delve into the jurisprudence
of international criminal law pertaining to sexual and gender based
violence followed by the core question of this essay – has the
entrenchment of sexual violence as international crimes in the Rome
Statute been successful to address such violence in armed conflicts?
Abstract: Strong anthropogenic impact has uncontrolled
consequences on the nature of the soil. Hence, up-to-date sustainable
methods of soil state improvement are essential. Investigators provide
the evidence that biochar can positively effects physical, chemical,
and biological soil properties and the abundance of mycorrhizal fungi
which are in the focus of this study. The main aim of the present
investigation is to demonstrate the effect of two types of plant growth
promoting bacteria (PGPB) inoculums along with the beech wood
biochar and mineral N additives on mycorrhizal colonization.
Experiment has been set up in laboratory conditions with containers
filled with arable soil from the protection zone of the main water
source “Brezova nad Svitavou”. Lactuca sativa (lettuce) has been
selected as a model plant. Based on the obtained data, it can be
concluded that mycorrhizal colonization increased as the result of
combined influence of biochar and PGPB inoculums amendment. In
addition, correlation analyses showed that the numbers of main
groups of cultivated bacteria were dependent on the degree of
mycorrhizal colonization.
Abstract: To maintain a healthy balanced loyalty, whether to art
or society, posits a debatable issue. The artist is always on the look
out for the potential tension between those two realms. Therefore,
one of the most painful dilemmas the artist finds is how to function in
a society without sacrificing the aesthetic values of his/her work. In
other words, the life-long awareness of failure which derives from the
concept of the artist as caught between unflattering social realities
and the need to invent genuine art forms becomes a fertilizing soil for
the artists to be tackled. Thus, within the framework of this dilemma,
the question of the responsibility of the artist and the relationship of
the art to politics will be illuminating. To a larger extent, however, in
drama, this dilemma is represented by the fictional characters of the
play. The present paper tackles the idea of the amorality of the artist in
selected plays by Tom Stoppard. However, Stoppard’s awareness of
his situation as a refugee has led him to keep at a distance from
politics. He tried hard to avoid any intervention into the realms of
political debate, especially in his earliest work. On the one hand, it is
not meant that he did not interest in politics as such, but rather he
preferred to question it than to create a fixed ideological position. On
the other hand, Stoppard’s refusal to intervene in politics is ascribed
to his feeling of gratitude to Britain where he settled. As a result,
Stoppard has frequently been criticized for a lack of political
engagement and also for not leaning too much for the left when he
does engage. His reaction to these public criticisms finds expression
in his self-conscious statements which defensively stressed the
artifice of his work. He, like Oscar Wilde thinks that the
responsibility of the artist is devoted to the realm of his/her art.
Consequently, his consciousness for the role of the artist is truly
reflected in his two plays, Artist Descending a Staircase (1972) and
Travesties (1974).