Abstract: In orthopedic surgery there are various situations in
which the surgeon needs to implement methods of cutting and
drilling the bone. With this type of procedure the generated friction
leads to a localized increase in temperature, which may lead to the
bone necrosis. Recognizing the importance of studying this
phenomenon, an experimental evaluation of the temperatures
developed during the procedure of drilling bone has been done.
Additionally the influence of the use of the procedure with / without
additional lubrication during drilling of bone has also been done. The
obtained results are presented and discussed and suggests an
advantage in using additional lubrication as a way to minimize the
appearance of bone tissue necrosis during bone drilling procedures.
Abstract: Bacterial strains capable of degradation of malathion
from the domestic sewage were isolated by an enrichment culture
technique. Three bacterial strains were screened and identified as
Acinetobacter baumannii (AFA), Pseudomonas aeruginosa (PS1),
and Pseudomonas mendocina (PS2) based on morphological,
biochemical identification and 16S rRNA sequence analysis.
Acinetobacter baumannii AFA was the most efficient malathion
degrading bacterium, so used for further biodegradation study. AFA
was able to grow in mineral salt medium (MSM) supplemented with
malathion (100 mg/l) as a sole carbon source, and within 14 days,
84% of the initial dose was degraded by the isolate measured by high
performance liquid chromatography. Strain AFA could also degrade
other organophosphorus compounds including diazinon, chlorpyrifos
and fenitrothion. The effect of different culture conditions on the
degradation of malathion like inoculum density, other carbon or
nitrogen sources, temperature and shaking were examined.
Degradation of malathion and bacterial cell growth were accelerated
when culture media were supplemented with yeast extract, glucose
and citrate. The optimum conditions for malathion degradation by
strain AFA were; an inoculum density of 1.5x 10^12CFU/ml at 30°C
with shaking. A specific polymerase chain reaction primers were
designed manually using multiple sequence alignment of the
corresponding carboxylesterase enzymes of Acinetobacter species.
Sequencing result of amplified PCR product and phylogenetic
analysis showed low degree of homology with the other
carboxylesterase enzymes of Acinetobacter strains, so we suggested
that this enzyme is a novel esterase enzyme. Isolated bacterial strains
may have potential role for use in bioremediation of malathion
contaminated.
Abstract: This paper presents an evolutionary algorithm for
solving multi-objective optimization problems-based artificial neural
network (ANN). The multi-objective evolutionary algorithm used in
this study is genetic algorithm while ANN used is radial basis
function network (RBFN). The proposed algorithm named memetic
elitist Pareto non-dominated sorting genetic algorithm-based RBFN
(MEPGAN). The proposed algorithm is implemented on medical
diseases problems. The experimental results indicate that the
proposed algorithm is viable, and provides an effective means to
design multi-objective RBFNs with good generalization capability
and compact network structure. This study shows that MEPGAN
generates RBFNs coming with an appropriate balance between
accuracy and simplicity, comparing to the other algorithms found in
literature.
Abstract: Assembly line balancing problem is aimed to divide
the tasks among the stations in assembly lines and optimize some
objectives. In assembly lines the workload on stations is different
from each other due to different tasks times and the difference in
workloads between stations can cause blockage or starvation in some
stations in assembly lines. Buffers are used to store the semi-finished
parts between the stations and can help to smooth the assembly
production. The assembly line balancing and buffer sizing problem
can affect the throughput of the assembly lines. Assembly line
balancing and buffer sizing problems have been studied separately in
literature and due to their collective contribution in throughput rate of
assembly lines, balancing and buffer sizing problem are desired to
study simultaneously and therefore they are considered concurrently
in current research. Current research is aimed to maximize
throughput, minimize total size of buffers in assembly line and
minimize workload variations in assembly line simultaneously. A
multi objective optimization objective is designed which can give
better Pareto solutions from the Pareto front and a simple example
problem is solved for assembly line balancing and buffer sizing
simultaneously. Current research is significant for assembly line
balancing research and it can be significant to introduce optimization
approaches which can optimize current multi objective problem in
future.
Abstract: The aim of this work was to apply extractive
distillation for acetonitrile removal from water solutions, to validate
thermodynamic criterion based on excess Gibbs energy to entrainer
selection process for acetonitrile – water mixture separation and show
its potential efficiency at isothermal conditions as well as at isobaric
(conditions of real distillation process), to simulate and analyze an
extractive distillation process with chosen entrainers: optimize
amount of trays and feeds, entrainer/original mixture and reflux
ratios. Equimolar composition of the feed stream was chosen for the
process, comparison of the energy consumptions was carried out.
Glycerol was suggested as the most energetically and ecologically
suitable entrainer.
Abstract: Anthocyanins are natural pigments with effective UV
protection but their topical use could be limited due to their
physicochemical characteristics. An attempt to overcome such
limitations by complexation of 2 major anthocyanin-rich sources, C.
ternatea and Z. mays, has potentiated its use as topical antiinflammatory.
Cell studies indicate no cytotoxicity of the
anthocyanin complex (AC) up to 1 mg/ml tested in HaCaT and
human fore head fibroblasts by MTT. Croton oil-induced ear edema
in Wistar rats suggests an effective dose of 5 mg/cm2 of AC as a
topical anti-inflammatory in comparison to 0.5 mg/cm2 of
fluocinolone acetonide. Niosomal encapsulation of the AC
significantly prolonged the anti-inflammatory activity particularly at
8 h after topical application (p = 0.0001). The AC was not cytotoxic
and its anti-inflammatory and activity was dose-dependent and
prolonged by niosomal encapsulation. It has also shown to promote
collagen type 1 production in cell culture. Thus, AC could be a
potential candidate for topical anti-inflammatory agent from natural
resources.
Abstract: The present study was done to evaluate the presence
of tetracycline resistance genes in Lactococcus garvieae isolated
from cultured rainbow trout, West Iran. The isolates were examined
for antimicrobial resistance using disc diffusion method. Of the 49
strains tested, 19 were resistant to tetracycline (38.7%), 32 to
enrofloxacin (65.3%), 21 to erythromycin (42.8%), 20 to
chloramphenicol and trimetoprim-sulfamethoxazole (40.8%). The
strains were then characterized for their genotypic resistance profiles.
The results revealed that all 49 isolates contained at least one of the
tetracycline resistance genes. Tet (A) was found in 89.4% of
tetracycline resistant isolates and the frequency of other gene were as
follows: tet (E) 42.1%, tet (B) 47.3%, tet (D) 15.7%, tet (L) 26.3%,
tet (K) 52.6%, tet (G) 36.8%, tet (34) 21%, tet (S) 63.1%, tet (C)
57.8%, tet (M) 73.6%, tet (O) 42.1%. The results revealed high levels
of antibiotic resistance in L. garvieae strains which is a potential
danger for trout culture as well as for public health.
Abstract: In situ modified cyclohexanone-formaldehyde resins
were prepared by addition of alendronic acid during resin
preparation. Clay nanocomposites in ketonic resins were achieved by
adding clay into the flask at the beginning of the resin preparation.
The prepared resins were used for the synthesis of fire resistant
polyurethanes foam. Both phosphorous containing modifier
compound alendronic acid and nanoclay increases fire resistance of
the cyclohexanone-formaldehyde resin thus polyurethane produced
from these resins. The effect of the concentrations of alendronic acid
and clay on the fire resistance and physical properties of
polyurethanes was studied.
Abstract: We have developed a new computer program in
Fortran 90, in order to obtain numerical solutions of a system
of Relativistic Magnetohydrodynamics partial differential equations
with predetermined gravitation (GRMHD), capable of simulating
the formation of relativistic jets from the accretion disk of matter
up to his ejection. Initially we carried out a study on numerical
methods of unidimensional Finite Volume, namely Lax-Friedrichs,
Lax-Wendroff, Nessyahu-Tadmor method and Godunov methods
dependent on Riemann problems, applied to equations Euler in
order to verify their main features and make comparisons among
those methods. It was then implemented the method of Finite
Volume Centered of Nessyahu-Tadmor, a numerical schemes that
has a formulation free and without dimensional separation of
Riemann problem solvers, even in two or more spatial dimensions,
at this point, already applied in equations GRMHD. Finally, the
Nessyahu-Tadmor method was possible to obtain stable numerical
solutions - without spurious oscillations or excessive dissipation -
from the magnetized accretion disk process in rotation with respect
to a central black hole (BH) Schwarzschild and immersed in a
magnetosphere, for the ejection of matter in the form of jet over a
distance of fourteen times the radius of the BH, a record in terms
of astrophysical simulation of this kind. Also in our simulations,
we managed to get substructures jets. A great advantage obtained
was that, with the our code, we got simulate GRMHD equations in
a simple personal computer.
Abstract: Given the importance of ports as links in the global
supply chains and because they are key elements to induce
competitiveness in their hinterlands, the number of studies devoted to
port governance, management and operations has increased in the last
decades. Some of these studies address the port governance model as
an element to improve coordination among the actors of the portlogistics
chain and to generate a better port performance. In this
context, the present study analyzes the governance of Port of Santos
through individual interviews with port managers, based on a
conceptual model that considers the key dimensions associated with
port governance. The results reinforce the usefulness of the applied
model and highlight some existing improvement opportunities in the
port studied.
Abstract: The demand of high quality services has fueled
dimensional research and development in wireless communications
and networking. As a result, different wireless technologies like
Wireless LAN, CDMA, GSM, UMTS, MANET, Bluetooth and
satellite networks etc. have emerged in the last two decades. Future
networks capable of carrying multimedia traffic need IP convergence,
portability, seamless roaming and scalability among the existing
networking technologies without changing the core part of the
existing communications networks. To fulfill these goals, the present
networking systems are required to work in cooperation to ensure
technological independence, seamless roaming, high security and
authentication, guaranteed Quality of Services (QoS). In this paper, a
conceptual framework for a cooperative network (CN) is proposed
for integration of heterogeneous existing networks to meet out the
requirements of the next generation wireless networks.
Abstract: The effect of a 3-dimensional (3D) blade on the turbine
characteristics of Wells turbine for wave energy conversion has been
investigated experimentally by model testing under steady flow
conditions in this study, in order to improve the peak efficiency and
stall characteristics. The aim of use of 3D blade is to prevent flow
separation on the suction surface near the tip. The chord length is
constant with radius and the blade profile changes gradually from the
mean radius to tip. The proposed blade profiles in the study are
NACA0015 from the hub to mean radius and NACA0025 at the tip.
The performances of Wells turbine with 3D blades has been compared
with those of the original Wells turbine, i.e., the turbine with
2-dimensional (2D) blades. As a result, it was concluded that although
the peak efficiency of Wells turbine can be improved by the use of the
proposed 3D blade, its blade does not overcome the weakness of
stalling.
Abstract: Due to the importance of ports to trade and economic
development of the regions in which they are inserted, in recent
decades the number of studies devoted to this subject has increased.
Part of these studies considers the ports as business agglomerations
and focuses on port governance. This is an important approach since
the port performance is the result of activities performed by actors
belonging to the port-logistics chain, which need to be properly
coordinated. This coordination takes place through a port governance
model. Given this context, this study aims to analyze the governance
model of the port of Santos from the perspective of port customers.
To do this, a closed-ended questionnaire based on a conceptual model
that considers the key dimensions associated with port governance
was applied to the international freight forwarders that operate in the
port. The results show the applicability of the considered model and
highlight improvement opportunities to be implemented at the port of
Santos.
Abstract: Yttrium oxide (Y2O3) films have been successfully
deposited with yttrium-ethylenediamine tetraacetic acid (EDTA·Y·H)
complexes prepared by various milling techniques. The effects of the
properties of the EDTA·Y·H complex on the properties of the
deposited Y2O3 films have been analyzed. Seven different types of the
raw EDTA·Y·H complexes were prepared by various commercial
milling techniques such as ball milling, hammer milling, commercial
milling, and mortar milling. The milled EDTA·Y·H complexes
exhibited various particle sizes and distributions, depending on the
milling method. Furthermore, we analyzed the crystal structure,
morphology and elemental distribution profile of the metal oxide films
deposited on stainless steel substrate with the milled EDTA·Y·H
complexes. Depending on the milling technique, the flow properties of
the raw powders differed. The X-ray diffraction pattern of all the
samples revealed the formation of Y2O3 crystalline phase, irrespective
of the milling technique. Of all the different milling techniques, the
hammer milling technique is considered suitable for fabricating dense
Y2O3 films.
Abstract: Violet Sr–Al–O:Eu2+ phosphor particles were
synthesized from a metal–ethylenediaminetetraacetic acid (EDTA)
solution of Sr, Al, Eu, and particulate alumina via spray drying and
sintering in a reducing atmosphere. The crystal structures and emission
properties at 85–300 K were investigated. The composition of the
violet Sr–Al–O:Eu2+ phosphor particles was determined from various
Sr–Al–O:Eu2+ phosphors by their emission properties’ dependence
on temperature. The highly crystalline SrAl12O19:Eu2+ emission phases
were confirmed by their crystallite sizes and the activation energies for
the 4f5d–8S7/2 transition of the Eu2+ ion. These results showed that the
material identification for the violet Sr–Al–O:Eu2+ phosphor was
accomplished by the low-temperature luminescence measurements.
Abstract: The knowledge of biodiesel density over large ranges
of temperature and pressure is important for predicting the behavior
of fuel injection and combustion systems in diesel engines, and for
the optimization of such systems. In this study, cottonseed oil was
transesterified into biodiesel and its density was measured at
temperatures between 288 K and 358 K and pressures between 0.1
MPa and 30 MPa, with expanded uncertainty estimated as ±1.6 kg⋅m-
3. Experimental pressure-volume-temperature (pVT) cottonseed data
was used along with literature data relative to other 18 biodiesels, in
order to build a database used to test the correlation of density with
temperarure and pressure using the Goharshadi–Morsali–Abbaspour
equation of state (GMA EoS). To our knowledge, this is the first that
density measurements are presented for cottonseed biodiesel under
such high pressures, and the GMA EoS used to model biodiesel
density. The new tested EoS allowed correlations within 0.2 kg·m-3
corresponding to average relative deviations within 0.02%. The built
database was used to develop and test a new full predictive model
derived from the observed linear relation between density and degree
of unsaturation (DU), which depended from biodiesel FAMEs
profile. The average density deviation of this method was only about
3 kg.m-3 within the temperature and pressure limits of application.
These results represent appreciable improvements in the context of
density prediction at high pressure when compared with other
equations of state.
Abstract: Background: Bleeding during first half of pregnancy
mostly originates from placenta, some abort, others are at risk of
complications. Objective: Study was done to know perinatal outcome
with bleeding up to 20 weeks in singleton pregnancy. Material
Methods: Subjects were 1020, equal controls managed over 2 years,
435 had viable pregnancy at admission, 135 excluded, 300 followed
for perinatal outcome, 99 (19.52% up to 10 weeks), 201 (39.18% of
11-20 weeks). Results: Hypertensive disorders occurred in 24% cases
of bleeding within 10 weeks, 22% 11-20 weeks 14.79% controls,
placenta previa 4% in 10 weeks, 0.9% 11-20 weeks, 0.97% controls,
prelabor rupture of membranes in 16%, 7.45% controls. 20% up to 10
weeks, 35% 11-20 weeks, 18% controls had fetal growth restriction,
34.34% up to 10 weeks 30.35% of 11-20 weeks 17.17% controls had
preterm births, perinatal mortality rate in study was 118.62, in
controls 68.16 (Uneventful pregnancy in 13.52% study, 46.11%
controls). Conclusion: Once bleeding occurs, one third continue
pregnancy, maternal neonatal outcome gets affected with variations
in cases of bleeding within first 10 weeks & 11-20 weeks.
Abstract: Esterification of p-bromo-m-cresol led to formation of
2-(4-bromo-3-methylphenoxy)acetate (1). 2-(4-Bromo-3-methyl
phenoxy)acetohydrazide (2) is derived from Compound (1) by
hydrazination. Compound (2) was reacted with different aromatic
aldehydes to yield N-(substituted benzylidiene)-2-(4-bromo-3-methyl
phenoxy)acetamide(3a-c). Cyclization of compound (3a-c) with
thioglycolic acid yielded 2-(4-bromo-3-methylphenoxy)-N-(4-oxo-2-
arylthiazolidin-3-yl) acetamide (4a-c). The newly synthesized
compounds were characterized on the basis of spectral studies and
evaluated for antibacterial and antifungal activities.
Abstract: Kigelia africana (Lam.) Benth. (Bignoniaceae) is a
reputed traditional remedy for various human ailments such as skin
diseases, microbial infections, melanoma, stomach troubles,
metabolic disorders, malaria and general pains. In spite of the fruit
being widely used for purposes related to its antibacterial and
antifungal properties, the chemical constituents associated with the
activity have not been fully identified. To elucidate the active
principles, we evaluated the antimicrobial activity of fruit extracts
and purified fractions against Staphylococcus aureus, Enterococcus
faecalis, Moraxella catarrhalis, Escherichia coli, Candida albicans
and Candida tropicalis. Shade-dried fruits were powdered and
extracted with hydroalcoholic (1:1) mixture by soaking at room
temperature for 72 h. The crude extract was further fractionated by
column chromatography, with successive elution using hexane,
dichloromethane, ethyl acetate, acetone and methanol. The
dichloromethane and ethyl acetate fractions were combined and
subjected to column chromatography to furnish a wax and oil from
the eluates of 20% and 40% ethyl acetate in hexane, respectively. The
GC-MS and GC×GC-MS results revealed that linoleic acid, linolenic
acid, palmitic acid, arachidic acid and stearic acid were the major
constituents in both oil and wax. The crude hydroalcoholic extract
exhibited the strongest activity with MICs of 0.125-0.5 mg/mL,
followed by the ethyl acetate (MICs = 0.125-1.0 mg/mL),
dichloromethane (MICs = 0.250-2.0 mg/mL), hexane (MICs = 0.25-
2.0 mg/mL), acetone (MICs = 0.5-2.0 mg/mL) and methanol (MICs =
1.0-2.0 mg/mL), whereas the wax (MICs = 2.0-4.0 mg/mL) and oil
(MICs = 4.0-8.0 mg/mL) showed poor activity. The study concludes
that synergistic interactions of chemical constituents could be
responsible for the antimicrobial activity of K. africana fruits, which
needs a more holistic approach to understand the mechanism of its
antimicrobial activity.
Abstract: The objective of this study is to analyze the
prophylactic usage of low molecular weight heparin (LMWH) along
pregnancy and the correlation between their usage and month/week
of pregnancy, in the Department of Gynecology and Obstetrics, at
Clinical Hospital in Tetovo. A retrospective study was undertaken
during 01 January – 31 December 2012. Over of one year, the total
number of patients was 4636. Among the 1447 (32.21%) pregnant
women, 298 (20.59%) of them were prescribed LMWH. The majority
of patients given LMWH, 119 (39.93%) were diagnosed
hypercoagulable. The age group with the highest attendance was 25-
35, 141 patients (47.32%). For 195 (65.44%) patients, this was their
first pregnancy. Earliest stage of using LMWH was the second month
of pregnancy 4 (1.34%) cases. The most common patients were 70
women along the seventh month (23.49%), followed by 68 in the
ninth month of pregnancy (22.81%). Women in the 28th gestational
week, were found to be the most affected, a total of 55 (78.57%) were
in that week. Clexane 2000 and Fraxiparine 0.3 were the most
common for which low molecular weight heparin was prescribed.
The number of patients which received Clexane 2000 was 84
(28.19%), followed by those with Fraxiparine 0.3 81 (27.18%). The
administration of LMWH is associated with long hospitalization
(median 14,6 days).