Abstract: Esterification of p-bromo-m-cresol led to formation of
2-(4-bromo-3-methylphenoxy)acetate (1). 2-(4-Bromo-3-methyl
phenoxy)acetohydrazide (2) is derived from Compound (1) by
hydrazination. Compound (2) was reacted with different aromatic
aldehydes to yield N-(substituted benzylidiene)-2-(4-bromo-3-methyl
phenoxy)acetamide(3a-c). Cyclization of compound (3a-c) with
thioglycolic acid yielded 2-(4-bromo-3-methylphenoxy)-N-(4-oxo-2-
arylthiazolidin-3-yl) acetamide (4a-c). The newly synthesized
compounds were characterized on the basis of spectral studies and
evaluated for antibacterial and antifungal activities.
Abstract: Alpinia galanga is rhizome, generally known as
Greater galangal and is selected for isolation of newer constituents
accountable for various therapeutic activities. Present study is
intended to isolate glycoside from Alpinia galanga rhizomes. Alpinia
galanga methanolic extract was column chromatograph and eluted
with ethyl acetate-methanol (99:1) to isolate compound β-Sitosterol
Diarabinoside. Herein, the isolation and structural elucidation of new
compound is described. Chemical investigation of methanolic extract
of rhizomes of Alpinia galanga furnished a new compound β-
Sitosterol Diarabinoside. The IR, NMR and MASS investigations of
isolated compound confirmed its structure as β-Sitosterol
Diarabinoside, which is isolated for the first time from a medicinal
plant or any synthetic source.