Abstract: MATCH project [1] entitle the development of an
automatic diagnosis system that aims to support treatment of colon
cancer diseases by discovering mutations that occurs to tumour
suppressor genes (TSGs) and contributes to the development of
cancerous tumours. The constitution of the system is based on a)
colon cancer clinical data and b) biological information that will be
derived by data mining techniques from genomic and proteomic
sources The core mining module will consist of the popular, well
tested hybrid feature extraction methods, and new combined
algorithms, designed especially for the project. Elements of rough
sets, evolutionary computing, cluster analysis, self-organization maps
and association rules will be used to discover the annotations
between genes, and their influence on tumours [2]-[11].
The methods used to process the data have to address their high
complexity, potential inconsistency and problems of dealing with the
missing values. They must integrate all the useful information
necessary to solve the expert's question. For this purpose, the system
has to learn from data, or be able to interactively specify by a domain
specialist, the part of the knowledge structure it needs to answer a
given query. The program should also take into account the
importance/rank of the particular parts of data it analyses, and adjusts
the used algorithms accordingly.
Abstract: The exploration of this paper will focus on the Cshaped
transition curve. This curve is designed by using the concept
of circle to circle where one circle lies inside other. The degree of
smoothness employed is curvature continuity. The function used in
designing the C-curve is Bézier-like cubic function. This function has
a low degree, flexible for the interactive design of curves and
surfaces and has a shape parameter. The shape parameter is used to
control the C-shape curve. Once the C-shaped curve design is
completed, this curve will be applied to design spur gear tooth. After
the tooth design procedure is finished, the design will be analyzed by
using Finite Element Analysis (FEA). This analysis is used to find
out the applicability of the tooth design and the gear material that
chosen. In this research, Cast Iron 4.5 % Carbon, ASTM A-48 is
selected as a gear material.
Abstract: This paper is to develop a fuzzy net present value (FNPV) method by taking vague cash flow and imprecise required rate of return into account for evaluating the value of the Build-Operate-Transfer (BOT) sport facilities. In order to clearly manifest a more realistic capital budgeting model based on the classical net present value (NPV) method, some uncertain financial elements in NPV formula will be fuzzified as triangular fuzzy numbers. Through the conscientious manipulation of fuzzy set theory, we will find that the proposed FNPV model is a more explicit extension of classical (crisp) model and could be more practicable for the financial managers to capture the essence of capital budgeting of sport facilities than non-fuzzy model.
Abstract: This study is designed to investigate errors emerged in written texts produced by 30 Turkish EFL learners with an explanatory, and thus, qualitative perspective. Erroneous language elements were identified by the researcher first and then their grammaticality and intelligibility were checked by five native speakers of English. The analysis of the data showed that it is difficult to claim that an error stems from only one single factor since different features of an error are triggered by different factors. Our findings revealed two different types of errors: those which stem from the interference of L1 with L2 and those which are developmental ones. The former type contains more global errors whereas the errors in latter type are more intelligible.
Abstract: In this paper, a new formulation for acoustics coupled with linear elasticity is presented. The primary objective of the work is to develop a three dimensional hp adaptive finite element method code destinated for modeling of acoustics of human head. The code will have numerous applications e.g. in designing hearing protection devices for individuals working in high noise environments. The presented work is in the preliminary stage. The variational formulation has been implemented and tested on a sequence of meshes with concentric multi-layer spheres, with material data representing the tissue (the brain), skull and the air. Thus, an efficient solver for coupled elasticity/acoustics problems has been developed, and tested on high contrast material data representing the human head.
Abstract: The contamination of 15 ground water resources
of a selected region earmarked for the emergency supply
of population has been monitored. The resources have been selected
on the basis of previous assessment of natural conditions
and the exploitation of territory in their surroundings and infiltration
area. Two resources out of 15 have been excluded from further
exploitation, because they have not met some of the 72 assessed
hygienic indicators of extended analysis. The remaining 13 resources
have been the subject of health risk analysis in relation
to the contamination by arsenic, lead, cadmium, mercury, nickel and
manganese. The risk analysis proved that all 13 resources meet
health standards with regard to the above mentioned purposefully
selected elements and may thus be included into crisis plans. Water
quality of ground resources may be assessed in the same way
with regard to other contaminants.
Abstract: In this paper a three dimensional thermal model of
high breaking capacity fuse with unequal fuse links is proposed for
both steady-state or transient conditions. The influence of ambient
temperature and electric current on the temperature distribution
inside the fuse, has been investigated. A thermal analysis of the
unbalanced distribution of the electric current through the fuse
elements and their influence on fuse link temperature rise, has been
performed. To validate the three dimensional thermal model, some
experimental tests have been done. There is a good correlation
between experimental and simulation results.
Abstract: In the past many uneconomic solutions for limitation
and interruption of short-circuit currents in low power applications
have been introduced, especially polymer switch based on the
positive temperature coefficient of resistance (PCTR) concept.
However there are many limitations in the active material, which
consists of conductive fillers. This paper presents a significantly
improved and simplified approach that replaces the existing current
limiters with faster switching elements. Its elegance lies in the
remarkable simplicity and low-cost processes of producing the device
using polyaniline (PANI) doped with methane-sulfonic acid (MSA).
Samples characterized as lying in the metallic and critical regimes of
metal insulator transition have been studied by means of electrical
performance in the voltage range from 1V to 5 V under different
environmental conditions. Moisture presence is shown to increase the
resistivity and also improved its current limiting performance.
Additionally, the device has also been studied for electrical resistivity
in the temperature range 77 K-300 K. The temperature dependence of
the electrical conductivity gives evidence for a transport mechanism
based on variable range hopping in three dimensions.
Abstract: In recent years, the use of vector variance as a
measure of multivariate variability has received much attention in
wide range of statistics. This paper deals with a more economic
measure of multivariate variability, defined as vector variance minus
all duplication elements. For high dimensional data, this will increase
the computational efficiency almost 50 % compared to the original
vector variance. Its sampling distribution will be investigated to make
its applications possible.
Abstract: The purpose of this study is mainly to predict collision
frequency on the horizontal tangents combined with vertical curves
using artificial neural network methods. The proposed ANN models
are compared with existing regression models. First, the variables
that affect collision frequency were investigated. It was found that
only the annual average daily traffic, section length, access density,
the rate of vertical curvature, smaller curve radius before and after
the tangent were statistically significant according to related
combinations. Second, three statistical models (negative binomial,
zero inflated Poisson and zero inflated negative binomial) were
developed using the significant variables for three alignment
combinations. Third, ANN models are developed by applying the
same variables for each combination. The results clearly show that
the ANN models have the lowest mean square error value than those
of the statistical models. Similarly, the AIC values of the ANN
models are smaller to those of the regression models for all the
combinations. Consequently, the ANN models have better statistical
performances than statistical models for estimating collision
frequency. The ANN models presented in this paper are
recommended for evaluating the safety impacts 3D alignment
elements on horizontal tangents.
Abstract: Feeder is one of the airships of the Multibody Advanced Airship for Transport (MAAT) system, under development within the EU FP7 project. MAAT is based on a modular concept composed of two different parts that have the possibility to join; respectively they are the so-called Cruiser and Feeder, designed on the lighter than air principle. Feeder, also named ATEN (Airship Transport Elevator Network), is the smaller one which joins the bigger one, Cruiser, also named PTAH (Photovoltaic modular Transport Airship for High altitude),envisaged to happen at 15km altitude. During the MAAT design phase, the aerodynamic studies of the both airships and their interactions are analyzed. The objective of these studies is to understand the aerodynamic behavior of all the preselected configurations, as an important element in the overall MAAT system design. The most of these configurations are only simulated by CFD, while the most feasible one is experimentally analyzed in order to validate and thrust the CFD predictions. This paper presents the numerical and experimental investigation of the Feeder “conical like" shape configuration. The experiments are focused on the aerodynamic force coefficients and the pressure distribution over the Feeder outer surface, while the numerical simulation cover also the analysis of the velocity and pressure distribution. Finally, the wind tunnel experiment is compared with its CFD model in order to validate such specific simulations with respective experiments and to better understand the difference between the wind tunnel and in-flight circumstances.
Abstract: Steel made pipelines with different diameters are used
for transmitting oil and gas which in many cases are buried in soil
under the sea bed or immersed in sea water. External corrosion of
pipes is an important form of deterioration due to the aggressive
environment of sea water. Corrosion normally results in pits. Hence,
using the finite element method, namely ABAQUS software, this
paper estimates the amount of pressure capacity reduction of a pipecontaining
a semi-elliptical pitting corrosion and the rate of corrosion
during the pipeline life of 25 years.
Abstract: In this research work, a novel parallel manipulator
with high positioning and orienting rate is introduced. This
mechanism has two rotational and one translational degree of
freedom. Kinematics and Jacobian analysis are investigated.
Moreover, workspace analysis and optimization has been performed
by using genetic algorithm toolbox in Matlab software. Because of
decreasing moving elements, it is expected much more better
dynamic performance with respect to other counterpart mechanisms
with the same degrees of freedom. In addition, using couple of
cylindrical and revolute joints increased mechanism ability to have
more extended workspace.
Abstract: In the territories where high-intensity
earthquakes are frequent is paid attention to the solving of the
seismic problems. In the paper are described two
computational model variants based on finite element method
of the construction with different subsoil simulation (rigid or
elastic subsoil) is used. For simulation and calculations
program system based on method final elements ANSYS was
used. Seismic responses calculations of residential building
structure were effected on loading characterized by
accelerogram for comparing with the responses spectra
method.
Abstract: The process of laser absorption in the skin during
laser irradiation was a critical point in medical application
treatments. Delivery the correct amount of laser light is a critical
element in photodynamic therapy (PDT). More amounts of laser
light able to affect tissues in the skin and small amount not able to
enhance PDT procedure in skin. The knowledge of the skin tone
laser dependent distribution of 635 nm radiation and its penetration
depth in skin is a very important precondition for the investigation of
advantage laser induced effect in (PDT) in epidermis diseases
(psoriasis). The aim of this work was to estimate an optimum effect
of diode laser (635 nm) on the treatment of epidermis diseases in
different color skin. Furthermore, it is to improve safety of laser in
PDT in epidermis diseases treatment. Advanced system analytical
program (ASAP) which is a new approach in investigating the PDT,
dependent on optical properties of different skin color was used in
present work. A two layered Realistic Skin Model (RSM); stratum
corneum and epidermal with red laser (635 nm, 10 mW) were used
for irradiative transfer to study fluence and absorbance in different
penetration for various human skin colors. Several skin tones very
fair, fair, light, medium and dark are used to irradiative transfer. This
investigation involved the principles of laser tissue interaction when
the skin optically injected by a red laser diode. The results
demonstrated that the power characteristic of a laser diode (635 nm)
can affect the treatment of epidermal disease in various color skins.
Power absorption of the various human skins were recorded and
analyzed in order to find the influence of the melanin in PDT
treatment in epidermal disease. A two layered RSM show that the
change in penetration depth in epidermal layer of the color skin has a
larger effect on the distribution of absorbed laser in the skin; this is
due to the variation of the melanin concentration for each color.
Abstract: Array signal processing involves signal enumeration and source localization. Array signal processing is centered on the ability to fuse temporal and spatial information captured via sampling signals emitted from a number of sources at the sensors of an array in order to carry out a specific estimation task: source characteristics (mainly localization of the sources) and/or array characteristics (mainly array geometry) estimation. Array signal processing is a part of signal processing that uses sensors organized in patterns or arrays, to detect signals and to determine information about them. Beamforming is a general signal processing technique used to control the directionality of the reception or transmission of a signal. Using Beamforming we can direct the majority of signal energy we receive from a group of array. Multiple signal classification (MUSIC) is a highly popular eigenstructure-based estimation method of direction of arrival (DOA) with high resolution. This Paper enumerates the effect of missing sensors in DOA estimation. The accuracy of the MUSIC-based DOA estimation is degraded significantly both by the effects of the missing sensors among the receiving array elements and the unequal channel gain and phase errors of the receiver.
Abstract: One of the main consequences of the ubiquitous usage of Internet as a means to conduct business has been the progressive internationalization of contracts created to support such transactions. As electronic commerce becomes International commerce, the reality is that commercial disputes will occur creating such questions as: "In which country do I bring proceedings?" and "Which law is to be applied to solve disputes?" The decentralized and global structure of the Internet and its decentralized operation have given e-commerce a transnational element that affects two questions essential to any transaction: applicable law and jurisdiction in the event of dispute. The sharing of applicable law and jurisdiction among States in respect of international transactions traditionally has been based on the use of contact factors generally of a territorial nature (the place where real estate is located, customary residence, principal establishment, place of shipping goods). The characteristics of the Internet as a new space sometimes make it difficult to apply these rules, and may make them inoperative or lead to results that are surprising or totally foreign to the contracting parties and other elements and circumstances of the case.
Abstract: Chatter vibration has been a troublesome problem for a
machine tool toward the high precision and high speed machining.
Essentially, the machining performance is determined by the dynamic
characteristics of the machine tool structure and dynamics of cutting
process. Therefore the dynamic vibration behavior of spindle tool
system greatly determines the performance of machine tool. The
purpose of this study is to investigate the influences of the machine
frame structure on the dynamic frequency of spindle tool unit through
finite element modeling approach. To this end, a realistic finite
element model of the vertical milling system was created by
incorporated the spindle-bearing model into the spindle head stock of
the machine frame. Using this model, the dynamic characteristics of
the milling machines with different structural designs of spindle head
stock and identical spindle tool unit were demonstrated. The results of
the finite element modeling reveal that the spindle tool unit behaves
more compliant when the excited frequency approaches the natural
mode of the spindle tool; while the spindle tool show a higher dynamic
stiffness at lower frequency that may be initiated by the structural
mode of milling head. Under this condition, it is concluded that the
structural configuration of spindle head stock associated with the
vertical column of milling machine plays an important role in
determining the machining dynamics of the spindle unit.
Abstract: Obesity is frequent attendant phenomenon of patients
with endocrinological disease. Between BMI and endocrinological
diseases is close correlation. In thesis we focused on the allocation of
hormone concentration – PTH and TSH, CHOL a mineral element Ca
in a blood serum. The examined group was formed by 100
respondents (women) aged 36 – 83 years, who were divided into two
groups – control group (CG), group with diagnosed endocrine disease
(DED). The concentration of PTH and TSH, Ca and CHOL was
measured through the medium of analyzers Cobas e411 (Japan);
Cobas Integra 400 (Switzerland). At individuals was measured body
weight as well as stature and thereupon from those data we
enumerated BMI. On the basis of Student T-test in biochemical
parameter of PTH and Ca we found out significantly meaningful
difference (p
Abstract: The bromination of five selected pharmaceuticals
(metoprolol, naproxen, amoxicillin, hydrochlorotiazide and
phenacetin) in ultrapure water and in three water matrices (a
groundwater, a surface water from a public reservoir and a secondary
effluent from a WWTP) was investigated. The apparent rate
constants for the bromination reaction were determined as a function
of the pH, and the sequence obtained for the reaction rate was
amoxicillin > naproxen >> hydrochlorotiazide ≈ phenacetin ≈
metoprolol. The proposal of a kinetic mechanism, which specifies the
dissociation of bromine and each pharmaceutical according to their
pKa values and the pH allowed the determination of the intrinsic rate
constants for every elementary reaction. The influence of the main
operating conditions (pH, initial bromine dose, and the water matrix)
on the degradation of pharmaceuticals was established. In addition,
the presence of bromide in chlorination experiments was
investigated. The presence of bromide in wastewaters and drinking
waters in the range of 10 to several hundred μg L-1 accelerated
slightly the oxidation of the selected pharmaceuticals during chorine
disinfection.