Abstract: MicroRNAs (miRNAs) are a class of non-coding
RNAs that hybridize to mRNAs and induce either translation
repression or mRNA cleavage. Recently, it has been reported that
miRNAs could possibly play an important role in human diseases. By
integrating miRNA target genes, cancer genes, miRNA and mRNA
expression profiles information, a database is developed to link
miRNAs to cancer target genes. The database provides experimentally
verified human miRNA target genes information, including oncogenes
and tumor suppressor genes. In addition, fragile sites information for
miRNAs, and the strength of the correlation of miRNA and its target
mRNA expression level for nine tissue types are computed, which
serve as an indicator for suggesting miRNAs could play a role in
human cancer. The database is freely accessible at
http://ppi.bioinfo.asia.edu.tw/mirna_target/index.html.
Abstract: The hydro-mechanical model for unsaturated soils has
been presented based on the effective stress principle taking into
account effects of drying-wetting process. The elasto-plastic
constitutive equations for stress-strain relations of the soil skeleton
have been established. A plasticity model is modified from modified
Cam-Clay model. The hardening rule has been established by
considering the isotropic consolidation paths. The effect of dryingwetting
process is introduced through the ¤ç parameter. All model
coefficients are identified in terms of measurable parameters. The
simulations from the proposed model are compared with the
experimental results. The model calibration was performed to extract
the model parameter from the experimental results. Good agreement
between the results predicted using proposed model and the
experimental results was obtained.
Abstract: In this paper, the processing of sonar signals has been
carried out using Minimal Resource Allocation Network (MRAN)
and a Probabilistic Neural Network (PNN) in differentiation of
commonly encountered features in indoor environments. The
stability-plasticity behaviors of both networks have been
investigated. The experimental result shows that MRAN possesses
lower network complexity but experiences higher plasticity than
PNN. An enhanced version called parallel MRAN (pMRAN) is
proposed to solve this problem and is proven to be stable in
prediction and also outperformed the original MRAN.
Abstract: Unlike general-purpose processors, digital signal
processors (DSP processors) are strongly application-dependent. To
meet the needs for diverse applications, a wide variety of DSP
processors based on different architectures ranging from the
traditional to VLIW have been introduced to the market over the
years. The functionality, performance, and cost of these processors
vary over a wide range. In order to select a processor that meets the
design criteria for an application, processor performance is usually
the major concern for digital signal processing (DSP) application
developers. Performance data are also essential for the designers of
DSP processors to improve their design. Consequently, several DSP
performance benchmarks have been proposed over the past decade or
so. However, none of these benchmarks seem to have included recent
new DSP applications.
In this paper, we use a new benchmark that we recently developed
to compare the performance of popular DSP processors from Texas
Instruments and StarCore. The new benchmark is based on the
Selectable Mode Vocoder (SMV), a speech-coding program from the
recent third generation (3G) wireless voice applications. All
benchmark kernels are compiled by the compilers of the respective
DSP processors and run on their simulators. Weighted arithmetic
mean of clock cycles and arithmetic mean of code size are used to
compare the performance of five DSP processors.
In addition, we studied how the performance of a processor is
affected by code structure, features of processor architecture and
optimization of compiler. The extensive experimental data gathered,
analyzed, and presented in this paper should be helpful for DSP
processor and compiler designers to meet their specific design goals.
Abstract: Shipping comb is mounted on Head Stack Assembly
(HSA) to prevent collision of the heads, maintain the gap between
suspensions and protect HSA tips from unintentional contact
damaged in the manufacturing process. Failure analysis of shipping
comb in hard disk drive production processes is proposed .Field
observations were performed to determine the fatal areas on shipping
comb and their failure fraction. Root cause failure analysis (RCFA) is
applied to specify the failure causes subjected to various loading
conditions. For reliability improvement, failure mode and effects
analysis (FMEA) procedure to evaluate the risk priority is performed.
Consequently, the more suitable information design criterions were
obtained.
Abstract: The purpose of this study was to survey the effect of
organizational communication system on the conflict in physical
education offices of Isfahan province. The research methodology of
this research was a descriptive study. All employees working in
physical education offices of Isfahan province were included in the
sample for this study (N= 236). Researcher made questionnaire and
demographic questionnaire were used as investigation instruments.
Based on the result of chi square test, there is significant difference
between organizational communication system and interpersonal
conflict. The most of participants evaluate communication in an
informal way and pointed out that the communication channels were
not open. Based on the result of binomial test, interpersonal conflict
exists in physical education offices of Isfahan.
Abstract: Based on the standard finite element method, a new
finite element method which is known as nonlocal finite element
method (NL-FEM) is numerically implemented in this article to
study the nonlocal effects for solving 1D nonlocal elastic problem.
An Eringen-type nonlocal elastic model is considered. In this model,
the constitutive stress-strain law is expressed interms of integral
equation which governs the nonlocal material behavior. The new
NL-FEM is adopted in such a way that the postulated nonlocal elastic
behavior of material is captured by a finite element endowed with a
set of (cross-stiffness) element itself by the other elements in mesh.
An example with their analytical solutions and the relevant numerical
findings for various load and boundary conditions are presented and
discussed in details. It is observed from the numerical solutions that
the torsional deformation angle decreases with increasing nonlocal
nanoscale parameter. It is also noted that the analytical solution fails
to capture the nonlocal effect in some cases where numerical
solutions handle those situation effectively which prove the
reliability and effectiveness of numerical techniques.
Abstract: Calcium is very important for communication among
the neurons. It is vital in a number of cell processes such as secretion,
cell movement, cell differentiation. To reduce the system of reactiondiffusion
equations of [Ca2+] into a single equation, two theories
have been proposed one is excess buffer approximation (EBA) other
is rapid buffer approximation (RBA). The RBA is more realistic than
the EBA as it considers both the mobile and stationary endogenous
buffers. It is valid near the mouth of the channel. In this work we have
studied the effects of different types of buffers on calcium diffusion
under RBA. The novel thing studied is the effect of sodium ions on
calcium diffusion. The model has been made realistic by considering
factors such as variable [Ca2+], [Na+] sources, sodium-calcium
exchange protein(NCX), Sarcolemmal Calcium ATPase pump. The
proposed mathematical leads to a system of partial differential equations
which has been solved numerically to study the relationships
between different parameters such as buffer concentration, buffer
disassociation rate, calcium permeability. We have used Forward
Time Centred Space (FTCS) approach to solve the system of partial
differential equations.
Abstract: Educating effective architect designers is an important
goal of architectural education. But what contributes to students-
performance, and to critical and creative thinking in architectural
design education? Besides teaching architecture students how to
understand logical arguments, eliminate the inadequate solutions and
focus on the correct ones, it is also crucial to teach students how to
focus on exploring ideas and the alternative solutions and seeking for
other right answers rather than one. This paper focuses on the
enhancing architectural design education and may provide
implications for enhancing teaching design.
Abstract: Security is an interesting and significance issue for
popular virtual platforms, such as virtualization cluster and cloud
platforms. Virtualization is the powerful technology for cloud
computing services, there are a lot of benefits by using virtual machine
tools which be called hypervisors, such as it can quickly deploy all
kinds of virtual Operating Systems in single platform, able to control
all virtual system resources effectively, cost down for system platform
deployment, ability of customization, high elasticity and high
reliability. However, some important security problems need to take
care and resolved in virtual platforms that include terrible viruses, evil
programs, illegal operations and intrusion behavior. In this paper, we
present useful Intrusion Detection Mechanism (IDM) software that not
only can auto to analyze all system-s operations with the accounting
journal database, but also is able to monitor the system-s state for
virtual platforms.
Abstract: In this paper, by constructing a special set and utilizing fixed point theory in coin, we study the existence of solution of singular two point’s boundary value problem for second-order differential equation, which improved and generalize the result of related paper.
Abstract: n-CdO/p-Si heterojunction diode was fabricated using
sol-gel spin coating technique which is a low cost and easily scalable
method for preparing of semiconductor films. The structural and
morphological properties of CdO film were investigated. The X-ray
diffraction (XRD) spectra indicated that the film was of
polycrystalline nature. The scanning electron microscopy (SEM)
images indicate that the surface morphology CdO film consists of the
clusters formed with the coming together of the nanoparticles. The
electrical characterization of Au/n-CdO/p–Si/Al heterojunction diode
was investigated by current-voltage. The ideality factor of the diode
was found to be 3.02 for room temperature. The reverse current of
the diode strongly increased with illumination intensity of 100
mWcm-2 and the diode gave a maximum open circuit voltage Voc of
0.04 V and short-circuits current Isc of 9.92×10-9 A.
Abstract: The impact of fixed speed squirrel cage type as well as
variable speed doubly fed induction generators (DFIG) on dynamic
performance of a multimachine power system has been investigated.
Detailed models of the various components have been presented and
the integration of asynchronous and synchronous generators has been
carried out through a rotor angle based transform. Simulation studies
carried out considering the conventional dynamic model of squirrel
cage asynchronous generators show that integration, as such, could
degrade to the AC system performance transiently. This article
proposes a frequency or power controller which can effectively
control the transients and restore normal operation of fixed speed
induction generator quickly. Comparison of simulation results
between classical cage and doubly-fed induction generators indicate
that the doubly fed induction machine is more adaptable to
multimachine AC system. Frequency controller installed in the DFIG
system can also improve its transient profile.
Abstract: A feeding trial was conducted to investigate the effect
of periodically use of garlic on performance and carcass
characteristics in broiler chickens. 240 1-day-old Ross broiler chicks
randomly allocated into the 10 dietary treatments (A, B, C, D, E, F,
G, H, I and J) for 6 wk. Treatment A or control group, received basal
diet (based on standards of Ross management guidelines) without
supplementation of garlic powder while B, C and D dietary
treatments were basal diet supplemented with 0.5, 1 and 3% garlic
powder, respectively for the whole time of experiment (6 weeks).
Birds in group E, F and G were fed control diet supplemented with
0.5, 1 and 3% garlic powder, respectively just in their starter diet (0-
21d). Birds in three other treatments (H, I and J) received control diet
for the first 21 days and 0.5, 1 and 3% of garlic powder was added to
their finisher diets, respectively. 1 and 3% supplemented groups in
finisher period had better performance as compared with other
groups. Since present study conducted in optimum and antiseptic
conditions, it seems that better or more responses could be expected
in performance if the raising conditions would not be healthy.
Abstract: Geographic Profiling has successfully assisted investigations for serial crimes. Considering the multi-cluster feature of serial criminal spots, we propose a Multi-point Centrography model as a natural extension of Single-point Centrography for geographic profiling. K-means clustering is first performed on the data samples and then Single-point Centrography is adopted to derive a probability distribution on each cluster. Finally, a weighted combinations of each distribution is formed to make next-crime spot prediction. Experimental study on real cases demonstrates the effectiveness of our proposed model.
Abstract: The objective of this work was to examine the changes
in non destructive properties caused by carbonation of CEM II
mortar. Samples of CEM II mortar were prepared and subjected to
accelerated carbonation at 20°C, 65% relative humidity and 20% CO2
concentration. We examined the evolutions of the gas permeability,
the thermal conductivity, the thermal diffusivity, the volume of the
solid phase by helium pycnometry, the longitudinal and transverse
ultrasonic velocities. The principal contribution of this work is that,
apart of the gas permeability, changes in other non destructive
properties have never been studied during the carbonation of cement
materials. These properties are important in predicting/measuring the
durability of reinforced concrete in CO2 environment. The
carbonation depth and the porosity accessible to water were also
reported in order to explain comprehensively the changes in non
destructive parameters.
Abstract: It is not a secret that, IT management has become
more and more and integrated part of almost all organizations. IT
managers posses an enormous amount of knowledge within both
organizational knowledge and general IT knowledge. This article
investigates how IT managers keep themselves updated on IT
knowledge in general and looks into how much time IT managers
spend on weekly basis searching the net for new or problem solving
IT knowledge. The theory used in this paper is used to investigate the
current role of IT managers and what issues they are facing.
Furthermore a research is conducted where 7 IT managers in medium
sized and large Danish companies are interviewed to add further
focus on the role of the IT manager and to focus on how they keep
themselves updated. Beside finding substantial need for more
research, IT managers – generalists or specialists – only have limited
knowledge resources at hand in updating their own knowledge –
leaving much initiative to vendors.
Abstract: Real options theory suggests that managerial flexibility embedded within irreversible investments can account for a significant value in project valuation. Although the argument has become the dominant focus of capital investment theory over decades, yet recent survey literature in capital budgeting indicates that corporate practitioners still do not explicitly apply real options in investment decisions. In this paper, we explore how real options decision criteria can be transformed into equivalent capital budgeting criteria under the consideration of uncertainty, assuming that underlying stochastic process follows a geometric Brownian motion (GBM), a mixed diffusion-jump (MX), or a mean-reverting process (MR). These equivalent valuation techniques can be readily decomposed into conventional investment rules and “option impacts", the latter of which describe the impacts on optimal investment rules with the option value considered. Based on numerical analysis and Monte Carlo simulation, three major findings are derived. First, it is shown that real options could be successfully integrated into the mindset of conventional capital budgeting. Second, the inclusion of option impacts tends to delay investment. It is indicated that the delay effect is the most significant under a GBM process and the least significant under a MR process. Third, it is optimal to adopt the new capital budgeting criteria in investment decision-making and adopting a suboptimal investment rule without considering real options could lead to a substantial loss in value.
Abstract: This paper proposes the authentication method using
ESA algorithm instead of using CAVE algorithm in the CDMA
mobile communication systems including IS-95 and CDMA2000 1x.
And, we analyze to apply ESA mechanism on behalf of CAVE
mechanism without the change of message format and air interface in
the existing CDMA systems. If ESA algorithm can be used as the
substitution of CAVE algorithm, security strength of authentication
algorithm is intensified without protocol change. An algorithm
replacement proposed in this paper is not to change an authentication
mechanism, but to configure input of ESA algorithm and to produce
output. Therefore, our proposal can be the compatible to the existing
systems.
Abstract: This paper presents an exploration into the structure of the corporate governance network and interlocking directorates in the Czech Republic. First a literature overview and a basic terminology of the network theory is presented. Further in the text, statistics and other calculations relevant to corporate governance networks are presented. For this purpose an empirical data set consisting of 2 906 joint stock companies in the Czech Republic was examined. Industries with the highest average number of interlocks per company were healthcare, and energy and utilities. There is no observable link between the financial performance of the company and the number of its interlocks. Also interlocks with financial companies are very rare.